Dyak012230.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila yakuba
Gene Symbol
su(Hw)
Assembly
GCA_016746365.1
Location
NC:18106567-18110779[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0013 0.082 13.8 1.9 1 20 218 237 218 239 0.94
2 12 4.2e-06 0.00026 21.7 0.4 3 23 290 311 288 311 0.93
3 12 0.37 23 6.1 0.0 1 23 317 339 317 339 0.94
4 12 8.3e-07 5e-05 23.9 2.4 1 21 346 366 346 367 0.95
5 12 9.4e-06 0.00057 20.6 1.0 2 23 379 400 378 400 0.96
6 12 0.00043 0.026 15.4 6.3 1 23 411 433 411 433 0.99
7 12 0.00012 0.0075 17.1 0.9 1 23 439 461 439 461 0.97
8 12 2.8e-05 0.0017 19.1 0.4 1 23 467 489 467 489 0.98
9 12 2.4e-06 0.00015 22.5 2.5 1 23 495 517 495 517 0.98
10 12 5.8e-06 0.00035 21.2 1.0 1 23 521 543 521 543 0.97
11 12 0.0002 0.012 16.4 0.3 1 21 551 571 551 575 0.92
12 12 2e-06 0.00012 22.7 0.4 3 23 596 617 594 617 0.97

Sequence Information

Coding Sequence
ATGAGTGCCTCCAAGGAGGGCAAGGACAAGAAGGGCAAGCTGTTGGGTGTGGAGAACATTTCGCCGCCCAAGGATAAGCGTCCGAGCACCAGGATGAAGCTTTTAAATGACGTGGGAGCTGGTGAGGATGCCGAGCCAACCACCACCACATCACGAACGCCCTCCAACAAGCAGGAAAAGCGTGGCATTGTCGCTGGATCGCGCATCAAAATACTCAATGAAGAAATACTGGGCACTCCAAAAGCTGAGAAACGGGGCGCCAGCAAGAGCACAGCTCCGACTGCCTCCACTGTAAAGATTCTAAATGAAAAGAAGACCCCCAGTGCCACCGTGACAGCCGTGGAAACGGCCAAGATCAAGACGTCTCCCAgtaaaagaaagaaaatggaaCACTATGTACTTCAGGCTGTGAAATCAGAAAATACCAAGGCGGACACCACGGTTACCGTAGTCACCGAGGAAGATGAGACCATTGATTTTATTCTAGCAGATGATGAGGAAGTGGTGCCGGGCAGAATTGAGAACAACAACGGCCAGGAGATCGTTGTCACCGAGGATGACGAGGATATAGGCgaggatggggatgaggaCGGTGAAGATTCATCGGGAAAGGGCAACTCTAGCCAGACGAAAATCAAGGAGATCGTGGAGCACGTGTGCGGCAAGTGCTACAAGACCTTCCGTCGGGTTCAGAGTCTAAAAAAGCATCTGGAGTTCTGTCGCTATGACAGCGGTTATCATCTGCGCAAGGCCGACATGCTAAAGAACCTGGAGAAGATCGAGAAGGATGCCGTAGTGATGGAGAAAAAGGACatctgcttctgctgcagcGAAAGTTACGACACCTTCCATCTGGGTCACATTAACTGTCCCGACTGCCCCAAGTCGTTCAAGACACAGACCAGTTACGAACGCCACATATTCATCACTCACTCCGAGTTCAGCGATTTTCCTTGCTCCATTTGCAACGCCAACTTGCGCAGCGAGGCTTTGTTGGCGCTCCACGAGGAACAGCACAAGTCACGCGGCAAGCCGTATGCATGCAAGATCTGCGGCAAGGACTTCACCCGCTCCTACCACTTGAAGCGCCACCAGAAGTACTCATCGTGCTCATCGAACGAGACCGATACGATGAGCTGCAAGGTGTGCGATCGCGTCTTTTATAGGCTGGACAATCTGCGATCGCATTTGAAGCAGCATTTGGGCACACAGGTGGTGAAGAAGCCGGAGTACATGTGCCACACGTGCAAGAATTGTTTCTACAGCCTGTCCACGCTAAACATCCACATACGCACTCATACGGGTGAGAAACCATTCGACTGCGATCTTTGCGACAAGAAGTTCTCTGCATTGGTGGCCCTTAAGAAGCATCGACGCTATCACACTGGCGAAAAACCGTACAGTTGCACTGTGTGCAACCAAGCATTTGCCGTGAAGGAAGTGCTCAATCGGCACATGAAGCGTCACACTGGAGAGCGTCCGCACAAGTGCGATGAATGCGGCAAGAGTTTTATCCAGGCCACTCAGCTGCGCACCCATTCCAAAACCCATATTCGTCCCTTTGCCTGCGATCAGTGCgatgaaaaattcaaaacagaGAAACAACTTGAGCGCCATGTCAAGACCCATTCTCGCACAAAACGCCCCGTCTTCTCCTGCGCCGAATGCAAGCGTAATTTCCGCACCCCAGCATTGCTCAAGGAGCACATGGACGAGGGAAAGCACAGCCcacaacaacaacgggcATCAAAGCGCTCGTCCACCAAACTTATGGAACGCACGGATTGCGCCATTTGCGATAAGAACTTTGACAGCAGCGATACCCTGCGACGGCACATACGCACCGTGCACGAATGCGATCCGGATGACATTTTCGGTGTTGAGCCGCAGACATCAAAGCGTGCAAAGAAGGTCATCGAATCGGAGGAGGTTGTACCAGTGGCGTTGAACTCTTCGGCGGGCTCGTTAATTTCCAGCCAAACGGATGGCAATGGCGTTGTGGTGCGTGAATTCCTGGTGGATGAAGCCGATGGCGAGGCCCAGACCATTACCCTAGAAAACGAAACATACACAATTCTGCCCTTGGACGGGGCCATCGAGGGAGAGCAGCTGACGGATGAGGCTGCCGTTAAACCTGAGACCAAAAAGGAGGAGACGCAGGTCTCGCCGGTGGTCAAGAAGGAGCAGCGTAAATCCCTGGCCGCCAGTCTGGCCGCTGCTATCGCCGATAATCTGGAAGAAGCGTCGAGCGAGGATGACTTCAGTGGAGAAATCCTAACGGAGGAGGACATAAAGCTCAAAGAAAACGTGGGTAAACTTATTGACATGCTAGTGGATCCCCCGATCTTGAAGAAATACGGCTGGCCCAATGCCCCCGAGGAGACGGTGCTCTGCAAAGTGATCGAGAACTGTGGCCACGACCTGACCAAAGGTGGCGAAAACTACGCTGAGCTCGACTACGGTAGCCGCATGCGAGAGTATTGCAAACTGCTCTTTACCGTGGTCATTCACAACGATTCCATCAAGTCGCTGCTCAATAATTTCCCCATTGACGATGTCATCGAGTATGTACTGGGAGATGAGGACCAGGAGGAAGGGGGTTTGGGCAAAGACAATGATGACAACGAGTCAAATTCCGATTATGAAGATGATGATGCGGAGTCGGACACAGGCGCAtctaaaaaaaaggaaattagAGAGAAGCGTGACAAAAAGGAAGTTTCGGCCAATTCCGAGAAGAAGGAGATCATAGCGAAGGCTGTGGATAAGGATAACTCAGAGGAGACTAAAAAGGAAGTGGTCAcagaaaataagaaaaaatcgATCCCATTGGAAGCCGAAAAAGAGAAGGTTTGA
Protein Sequence
MSASKEGKDKKGKLLGVENISPPKDKRPSTRMKLLNDVGAGEDAEPTTTTSRTPSNKQEKRGIVAGSRIKILNEEILGTPKAEKRGASKSTAPTASTVKILNEKKTPSATVTAVETAKIKTSPSKRKKMEHYVLQAVKSENTKADTTVTVVTEEDETIDFILADDEEVVPGRIENNNGQEIVVTEDDEDIGEDGDEDGEDSSGKGNSSQTKIKEIVEHVCGKCYKTFRRVQSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLALHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSKTHIRPFACDQCDEKFKTEKQLERHVKTHSRTKRPVFSCAECKRNFRTPALLKEHMDEGKHSPQQQRASKRSSTKLMERTDCAICDKNFDSSDTLRRHIRTVHECDPDDIFGVEPQTSKRAKKVIESEEVVPVALNSSAGSLISSQTDGNGVVVREFLVDEADGEAQTITLENETYTILPLDGAIEGEQLTDEAAVKPETKKEETQVSPVVKKEQRKSLAASLAAAIADNLEEASSEDDFSGEILTEEDIKLKENVGKLIDMLVDPPILKKYGWPNAPEETVLCKVIENCGHDLTKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEEGGLGKDNDDNESNSDYEDDDAESDTGASKKKEIREKRDKKEVSANSEKKEIIAKAVDKDNSEETKKEVVTENKKKSIPLEAEKEKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00486704;
90% Identity
iTF_00591825; iTF_00504819; iTF_00607899; iTF_00539789; iTF_00592520; iTF_00596783;
80% Identity
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