Dwil013656.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila willistoni
Gene Symbol
Rreb1
Assembly
GCA_018902025.1
Location
JAFEWB010000698.1:5185591-5192042[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.005 0.41 11.3 0.6 1 21 243 263 243 265 0.96
2 13 0.00029 0.024 15.2 0.2 1 23 275 297 275 297 0.98
3 13 0.74 60 4.5 1.1 1 13 303 315 303 316 0.91
4 13 1.4 1.1e+02 3.7 0.3 2 23 346 368 345 368 0.92
5 13 2.1 1.7e+02 3.1 6.2 2 19 374 391 374 393 0.97
6 13 0.0072 0.59 10.8 0.1 1 23 565 587 565 587 0.97
7 13 1.1e-05 0.00087 19.7 0.7 1 23 597 619 597 619 0.99
8 13 0.00072 0.059 14.0 2.0 1 23 625 648 625 648 0.97
9 13 1.3 1.1e+02 3.7 0.3 1 16 922 937 922 939 0.89
10 13 7.4e-05 0.0061 17.1 0.3 2 23 1340 1361 1339 1361 0.97
11 13 0.12 10 6.9 6.3 1 23 1367 1390 1367 1390 0.97
12 13 0.0073 0.59 10.8 0.5 3 23 1620 1640 1618 1640 0.96
13 13 0.0012 0.094 13.3 4.8 1 23 1646 1668 1646 1668 0.99

Sequence Information

Coding Sequence
ATGCTAGCAACAACAACAACAACAACAACATCCACTGATATGGAACGTCAACGTAGAGATTCCACAACCTCAGAATCCTCATTGGAACATCTTGATCTTGGCCGCACACCAAAGAAATTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGCCGCCGCTGCTAGCGCCAGCATTGTAATCGATGGCCCAGCCGATGCCAATTCACTGCGCAAGAAATTTCGCTTGAACCACAGCAATAGCAGCAGTCTAATCAATGGCGAACTATCCGAATCGGGTTTCGTCGATGGCAGCGCACACAGTGGCTATCTAATTGGCAATAGTCATGCCTCTGCCGTTATTAGTGCTGCTGCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGGGCTCCTCTTCGCCTCAAGGCCTTTGCATGTCATCGTCCAGTGCTGGCGGCGATGAGCACATGAAATATGTATGCCCCATCTGTGAGGTTGTCTCGGCCACGCCCCATGAGTTTACCAATCACATCCGATGTCATAATTATGCCAATGGCGATACCGAAAATTTCACCTGTCGCATTTGCTCCAAGGTACTATCCTCAGCCTCATCTTTGGATAGGCATGTTCTGGTACATACAGGTGAACGACCCTTTAATTGTCGCTACTGCCACCTGACATTTACCACAAATGAAGTGGAAGTATCCATCACTAGTACACCAGATGTTGCCGCTCTATTGGCTGGCGCCTCGAGATCAGCATCACCCGCAACTCCACTGATAAGTTGTCCCGTCTGTTTATCCGAATTCGAATCCCTGCCCAGTTTATGCCAACATTTGGATCAACAACATTCCGATATATTGGCCAAATGTCGTGAGTGTGAAGTCATCTTTTCGAGTCACAAGCAACTGCAGAAACATTGCTGTCGCGGTGGCTCATCGTCCAGTGGTTTGCCGCCCCTCCTAAGAGCGAGTAGCTCACCATTGCATGGCGAACAAGAGGATGACGACGACGTCGACCGCGATGATGATGATGATCGAGAGATGCGACGTGATGGCATGGACACTGACCATCGCGATGAAGTCAAGGTGGAAAAAGAAGCCGAAGCCGAGGCCAAGCAGCGTGACGATTTCTTTCATCATTTGTATTTGAAGAGCAAAACCGAACATGCCCATATGTCCGAGGATAACAATGAGTTGGTCACATCGCCACCATCGCCCATTAAGCATGAACCGAATGATAGCAAAGATTTGGCCGATATACAAAGCATCCTGAACATGACCAGTTCGAGTTGTACATCCAGTTTTCTGCGCAACTTTGAGCAATCGGTCAATACGCCATGCTCGTCGAGTCAATACAGTCTGGATGGCCGGGATCAGGAGGAGGAGGCCCAAGATGTCTTCACCTCGGAATTCCGTCGCATGAAATTGCGTGGCGAATTCCCCTGCAAATTGTGTACGGCAGTTTTTCCCAATTTGCGTGCTCTCAAGGGGCACAATCGGGTGCATTTGGGTGCAGTTGGACCCGCTGGTCCCTTCCGTTGCAACATGTGTCCCTATGCCGTGTGCGACAAGGCCGCCCTGGTGCGGCACATGCGCACCCATAATGGGGATCGTCCGTATGAGTGTGCCGTCTGCAATTACGCCTTCACCACCAAGGCGAATTGTGAGCGCCATTTGAGGAATCGTCATGGCAAAACCAGTCGTGAGGATGTCAAACGTGCCATTGTCTACCATCCGGCCGAGGATGCCAGTTGCGGTGAGGGTGAGGGTAAATCCCGTTTAAATGACACCGATGAGAGTTATCGTTCGGCATCGCCGCCACCGCTAGAGGTGACTGCTGCCTCCCAACTGAAGCATATGCTGATGAACGATGGCCCAGGAGTGACGCAAAGTGTGCAACCGCCACCACTTAAGATCCAGGTTAAGAGCCTGGATCAGTTAGTGGAGAAGCAAACACCCGCCATTAAGGCGACACCATCGCCAGCAGCAAGTGCTATTGATCTCTCAATGGATGTGCTAGATCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTCCGCAATCTAATGTTTCAACAATCCTCTGGATTTCCCTTCTTTAACTTCATGACACCACCAGCTCCGCCGCCACAATCAACATCGTCTGCTGGCTCGGCCGTTGGAGAGAAATTGCCACCGTCAAGTGCCATGCAGCAGCAGCAACAACAAATGAGCCCCTCGAGCAATCGTCTGTCCCTGCTGCCCGGTGGTCCAGTCAAAATGGTCATCAAGAATGGTGTCCTAATGCCCAAACAGAAGCAACGTCGCTATCGCACCGAACGTCCCTTTGCCTGTGAGCATTGCTCGGCAAGATTTACATTGCGTTCGAATATGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCACACCCATTTCGGAGCAGGTGAAATATGCCATATTGGCCCAACAATTGAAGGCACACAAGAACACGGATTTGTTGCAACAGGCATTGGCCCATGGATCGAGCAGTGTGGCAGCAGCAGCGGCAGCTTCATCTCACTTGATGAACTTCAATTATGCCTTGGCCAATGGAAACGCCAATGTCAATGGCAACAGTAATGGAAATGCTCATGGAAATGGTCATAGTTTGGCCATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACAAGCAGCTCACGATGTGGATATGGACAAAAAGCTGGTGGTAATTGTGGATGATGAGCAGCAATCGCATGGCAAAGATTTGCCACAAACCATTGAGAACATGGCCAGTAACGAGGCAGCCAAAAAGGTGGCCGAAACCATTTTAGAGCAGGCCATCAAAGCTGGCAAACCCATAAGCCATGAAGTGGAACCAACTTCCACTACAGTTGCCAGTAGCCATCAGGCGCCATCCACAATGAAGTCGATGATTGCTCAGGTTGAGTCCGTGGCCAAGTCACTGAAAGATGTGGCCAGTTCACCATTCAATAAAGATGAATCTCCACTCTCCGATTTGGTGCCGGTGTCCAAGCTAGTGGACAATGCCACAAGCAATCAATCGATGCAAAGTTTCACCAGTTATTTTCGTCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCTCGGGCAGCGCCAGCGAGAGTAATAACTCCGGCACCGAAGATGTCACCAGCAGCAGTAGCAGTGGCCAAGAGCCCAAAAAGAAATCCGCCTACAGTCTGGCCCCCAATCGTGTCTCGTGTCCCTATTGCCAGCGTATGTTCCCCTGGAGCAGTTCCCTGAGACGGCACATTTTGACCCACACCGGGCAGAAGCCATTCAAATGCTCTCACTGCCCATTGCTCTTTACCACCAAGAGCAATTGTGATCGTCATTTGTTGAGGAAGCATGGCAATGTCGAATCGGCCATGTCCGTGTATGTGCCCACCGAGGATGTGAATGAACCGATACCAGTGCCCAAATCAGTGGAAGAAATCGAATTGGAGGAACAACGTAAGCGCCAAGAGGCCGAGCGCGAGAAGATCGAATTGGAACGAGAACGGGAGCGAGAGCGTGAACTTGAGCGTGAGCGAGAACGTGAAAGGCAATTGGAACGAGAGAGGGAAAAGGAGAGAGAACGTGAGCGAGAACGAGAATTGGAGTTGGAGCGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAGTAACGAGTTGGCCAATGGCGATTTGCCCTTCAAGTGCCATCTGTGTGAATGTTCGTTTAGCGAGCGTTTACAGTGCTTGGATCACATTAAGCAAGCGCATGCCCATGAATTTGCCTTGCTCTTGGCCAAGGGGGCTATCGAAACGGATGAACCCACCCAGGGAGCAAACGCAGCAGCGACGGCGGCGGCGGCGACAGTGCAGCCAACTGCTCCCCAATCCGATGATGAAGGATCTTTGGGCATGGCCGGCAATGGTCGTGGTGGTTCTGGTAAATATCCCGATTATAGCAATCGCAAAGTGATTTGCGCTTTTTGTGTTCGTCGATTCTGGTCCACTGAGGATTTGCGTCGTCATATGCGTACCCATTCGGGTGAGAGGCCATTTCAGTGTGAGATTTGCCTGCGTAAATTCACATTGAAGCATAGCATGTTGCGGCACATGAAGAAGCATAGTGGACGTTCCCATAATGCTGGAGAGATGCAAGGTGGCTCCGATTGTTCGGATGATGAGCAAATTATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATTGGGACTACGTCTACCGAAATTGCATGAGCTACTGGACAAGGCGAACGAGTGGCGAGCCAGTCGTTTGGGCGAGCACAAAGAGAATTTGGGCGAGCAACAACACCGTGCAACAACACCGGGAGCAACTCCATCTGCTGTGGCTGGTTCAACCGATCTCATTGGCAATCTATTGGGCATCAGCGATCAGGGTATATTGAACAAATTGCTCTCGTCCGCCGATGAGGCAGCCAAATTTCTGGGAGTGGACAAGTAA
Protein Sequence
MLATTTTTTTSTDMERQRRDSTTSESSLEHLDLGRTPKKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAAAASASIVIDGPADANSLRKKFRLNHSNSSSLINGELSESGFVDGSAHSGYLIGNSHASAVISAAAXXXXXXXXXXXXXXXXXXXXXXXSGSSSPQGLCMSSSSAGGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNEVEVSITSTPDVAALLAGASRSASPATPLISCPVCLSEFESLPSLCQHLDQQHSDILAKCRECEVIFSSHKQLQKHCCRGGSSSSGLPPLLRASSSPLHGEQEDDDDVDRDDDDDREMRRDGMDTDHRDEVKVEKEAEAEAKQRDDFFHHLYLKSKTEHAHMSEDNNELVTSPPSPIKHEPNDSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCGEGEGKSRLNDTDESYRSASPPPLEVTAASQLKHMLMNDGPGVTQSVQPPPLKIQVKSLDQLVEKQTPAIKATPSPAASAIDLSMDVLDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRNLMFQQSSGFPFFNFMTPPAPPPQSTSSAGSAVGEKLPPSSAMQQQQQQMSPSSNRLSLLPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVTPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAAAAAASSHLMNFNYALANGNANVNGNSNGNAHGNGHSLAIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQAAHDVDMDKKLVVIVDDEQQSHGKDLPQTIENMASNEAAKKVAETILEQAIKAGKPISHEVEPTSTTVASSHQAPSTMKSMIAQVESVAKSLKDVASSPFNKDESPLSDLVPVSKLVDNATSNQSMQSFTSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGQEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVNEPIPVPKSVEEIELEEQRKRQEAEREKIELERERERERELERERERERQLEREREKERERERERELELERXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSNELANGDLPFKCHLCECSFSERLQCLDHIKQAHAHEFALLLAKGAIETDEPTQGANAAATAAAATVQPTAPQSDDEGSLGMAGNGRGGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGEMQGGSDCSDDEQIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLGLRLPKLHELLDKANEWRASRLGEHKENLGEQQHRATTPGATPSAVAGSTDLIGNLLGISDQGILNKLLSSADEAAKFLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00571406;
90% Identity
-
80% Identity
-