Dwil016090.1
Basic Information
- Insect
- Drosophila willistoni
- Gene Symbol
- -
- Assembly
- GCA_018902025.1
- Location
- JAFEWB010000715.1:5576688-5582527[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00036 0.029 14.9 2.0 1 23 158 180 158 180 0.97 2 13 0.48 40 5.1 1.7 3 23 188 209 186 209 0.94 3 13 0.001 0.085 13.5 2.4 1 23 366 388 366 388 0.98 4 13 0.0012 0.094 13.3 1.9 3 23 765 785 764 785 0.92 5 13 0.046 3.8 8.3 1.4 1 23 791 814 791 814 0.98 6 13 1.3 1.1e+02 3.7 1.6 2 23 851 872 850 873 0.92 7 13 0.0041 0.33 11.6 0.8 1 23 894 917 894 917 0.97 8 13 0.00092 0.076 13.6 0.7 1 23 1187 1210 1187 1210 0.90 9 13 0.061 5 7.9 7.4 1 23 1222 1244 1222 1244 0.98 10 13 1.3e-05 0.0011 19.5 2.2 1 23 1249 1272 1249 1272 0.97 11 13 0.0064 0.52 11.0 4.6 1 23 1285 1310 1285 1310 0.95 12 13 0.00028 0.023 15.3 0.8 1 23 1315 1337 1315 1337 0.97 13 13 3.1e-05 0.0025 18.3 0.2 1 23 1344 1367 1344 1367 0.97
Sequence Information
- Coding Sequence
- ATGCCAATGCCAAGTCAAATCAAGAGAAGAAGCAACGAAAGGGCGAAAGCGGAGCTTCAGTTCATCAAGTCCAATGCAAATTACGAATACGTTTGTCGCTGCTGTCTCAAATCGGACGCGGATTTCATTCAACTGGATACGTTGATGGTATCACGAAACTTGGAGGGAAATGATGAATCGGATAAAATCCCTTTATTGCGTTGCTTACTCTTTTGCATACGCACGGATAATAAACCCGATTTGCCACAATTAATCTGCACGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCTTTGCCGTAAACTATGTTCAGATAAGCCAACACATTCGCGGCTTGGAGTGCAGCTTAATGGCAATTTTAGACATGAGACGGCGCCAAAGGAAGTCCCTTCACCAGACAGCAAGGCGAGATCGCAGAAGTCGGGCAATATCCGCCATGAATGCAAAATTTGTGGCACAGTGGTACACAATCGTATGGAACTTAAGCAGCACATACGTCTGCACAGAGATACAATCATTCAGAATTGCTCGATGTGCATTTTTAGTACGATAAAGCAGAGCCATCTAATGGAACACTATCGAGTGATGCACAATCTAACAACAGCTCAGGCGGAAGATCGCATTAATTTGGAACAACTTGAACAAAAACTGCAAGAAGGTCCTAAAGTTTGCACTCTAGAGGATATTGAAATGCTTATACCGACTGTATTGACACCCGAGGATTATGCTCAGCCAAAAAGTGAATACAATATTGAGCCACACTCGATGCCCAATAAGGAGACAAGTGCGAATAATGTTAGCATTGGCACGGAATTCCTTGTCATGCCTGATGGATCACTACAACAAGTGAATGGTGGTGGAGTCCTTTTTGAATATATCGATGACAGCAAACGTAATGTGGCACCCACGAGCAATTTAAATTTACAAACTCTTCTTGGAAATGACAACCTATCCCTCGATCCCATGGATATAGATATTAATGACCTTATTGTGGAGGAAAATCTACCGCAAATAAAAACCAAGCCAAGACCTGGAAAAATGGCAGCTGCTACTTTCAAGCACAAGTGCACAATTTGTATGAAATCATTTCCCACTTTGGCCCGCTTAAAATCTCATCAATTAACCCACAGTAATTTACCCAAATTTCATTGCGATCAGTGTAATTTCTTTTCGCTGCTTAGCTCTGATCTTGCCTATCATCATAAAGTAATGCATCAGGAGCCGCCGACACCGGCCCCGGTCCCAGCCCCGGCTCAAACATCGACTGTAGAACAGGGTGAGATATTATCATGTGATCTGTGCCTGTTCGAGACAAGGATATCAAATGAGCTGTATGACCATTATACTGACAAACACATGGTTCGTCCCACAGAGGTGCAATTACGCCCCTGTTGGTCTGGTGGCGCGGAGACAGTGGTAAACACGGCAATCCCTCAATTGCCGACGGATCAAGGGCAAAATATTGTTAATCCTTATCCAGTGCCTGTACAGCAAATTCTTCCACAAACCGCCACAAATATTATTGCGCAGCAGCCGGCACAGGCGAATACAACAGCAACTATAACACCAATGGGCGATATTAGTGTGGTTGTTGATGCAACACCATTATTTTTCCCCAATGGCACGCAAACAGCTGTGACTACAGTTGTCCCACTAGCACCACCACCACCACCACCACCTGCACCAGCACCACCATTGCAAGCTTCCACAGTTCCTTCAGCTATTGTGGATAATAGCAATATCAATTGTACCAACACCACCACCAACACATATGTTGAAGCATTTCCAGAAATCTCAGCCAACGAGAATCTTGTCCAGACAACTGAGCAGACAACTATTCCGCCAATCCCGAATCCAAATTTACCAACAACTTTTGGCGATATGCAAGACTTTATCGATAATACAGATGTGGCAGCCATATGCACCATACCAGCGGATGGTATGCCCGTTGTTGATGGCGATGATATAGTTATTGATAATAATAATATAAGCTTAGATTTTGATGCCGAAAATCTCTTTGGTGAATTCGAAGAGGAGGAAGAGGGTGGTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGAGACATTTGCAAAAACCATATTGCATCTATTGCAACAAAAAGTTTACCAGCCAATACAAATTCGAGAATCATATGTTTGTTCATAGGGGTCTGGCTCCCTATCGATGTGAATTGTGCACAAATCTTTACAATATGAAACGTCTACTTATACGGCATTACAAGACCGTACACAAACGCATGCCCACCCGCGATATGGTCCAGGCAAAGGGAGATAAAATAACAGTAGCTCGTTCTAATAAGGAAACCATTCAGGTTGATGTCAATAAAGATCCAATGCTTATGTGCGCCAAATGTCCATTTGAGTGTGAGTCGGATGCGGATATGAAAAAGCATTTAAATGCTCATCATGGCATAAATGATGGTGTTTCCGTACATGCCAATGAAGTGTTTATTATACGTAAATTGCCATTTGAGTGCCCACGTTGTATACGTTCGTTTGCTGCCAAAAGGACACTAACACGTCATTTACAACGTAGTCACCTGGTGGACACCATAATTGAGCTAACAGGTCCAGCCGCAACAATACCATCACCAAGCCAAACCGAAACCAATGCGGTGGCAAACGAAATCGTGCCATTGAACAATGCCGTAGATGCCACCGCAGAAAAGGAAGCTGACACACCGGTAGCGGCTCCTGTTCCTGATGACACAGCGATGGTTCCCGTTGCTGCTGACACATCGATGGGGGCTGCTGCTGCTGCTAATGCTGGAATAGATGGAATAAATGTCACCGAATGCGAAACCACCGATACACTCGTTCAAAGTGAGAAAGAGGCTGAAGGTGAAGCTGCTGCTGCAACAGTGGAAGAAAATGAACCTGCGGCTTTATCAACAGCCAATTCGGAACCATCTACTTTGGAAGTAAAGCCAACTGAAGTTACTACTGCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACAATTTTTAATACACCAACACACTTCGATTTCGATTATGATTTTATGGGTGATAGTACATCTACGCCCAATGGTAACATCAATACCCCAAATCCCGATTCTAACAATACCAATCCCAGCAGTACTACCACTACTACAAACAATAACAATAATAACAACAACAACAACACTACTACAACAGATGGTTATACACCAGCAGCCGAAGAGCTTCCCAGTCATGTACTCAATGGCAGTGACAAGTTATTAACTGCCGCCACCATGGAGCCATCACCCATTAAGGACGGACGAACGCGTCTTCCACGCACCCCGATTTTTGTATGCAAATTGTGCAATAAGACATTTGATGAACTAAGTAAACTCGTTAAACATGAAACCGAAATGCATTCTGGCGGAGAGCCGCGTCGAGTTGCCTTCCAGCACAAGTGTTCCACATGTCATGCAACGTTTCGTACCCTTACATTGCTAAAGTTTCACATGAAACGACATTTGGCACGCCGATTTCAATGCAACCGCTGTCCCAAGTGCTTTATCAAGAAGCCGGAATTGGAGCGACATATCTTAATGAAGCACGCAGAAAAACATGACACGAGCAGCAAAGATAAAGCCTTCAGATGCTCATTGAATGGTTGTACGAAGACGTTTAATTTTAAACATCATATGGTTCGTCATCAAAATGCCGTGCATCTGAAGGTTCGTCATATCTGCAATATTTGTGAAAAAGAGATGATAAATAGTTTCAATTTGAGAGTTCATATGCGGATTCACAGGGGCAATGGACAGTCGTACAAGTGTCCGAATTGTGATAAAACCTACGTGCGACGCGGACCGCTTCGTCTACATGCTCGTCAAGCCCATCAACTTGAGCTAACTGAAAGCGATTGGGCCGGAATGTTATGCAATAATGTTCGCTCCAACAGTTTGCACGTGAAAAAGCCTTCACGTAAAAAGAAAACTTCAGAGGCACCAGCCGGCGACTAA
- Protein Sequence
- MPMPSQIKRRSNERAKAELQFIKSNANYEYVCRCCLKSDADFIQLDTLMVSRNLEGNDESDKIPLLRCLLFCIRTDNKPDLPQLICTXXXXXXXXXXXXXXXXXXXXXXLCRKLCSDKPTHSRLGVQLNGNFRHETAPKEVPSPDSKARSQKSGNIRHECKICGTVVHNRMELKQHIRLHRDTIIQNCSMCIFSTIKQSHLMEHYRVMHNLTTAQAEDRINLEQLEQKLQEGPKVCTLEDIEMLIPTVLTPEDYAQPKSEYNIEPHSMPNKETSANNVSIGTEFLVMPDGSLQQVNGGGVLFEYIDDSKRNVAPTSNLNLQTLLGNDNLSLDPMDIDINDLIVEENLPQIKTKPRPGKMAAATFKHKCTICMKSFPTLARLKSHQLTHSNLPKFHCDQCNFFSLLSSDLAYHHKVMHQEPPTPAPVPAPAQTSTVEQGEILSCDLCLFETRISNELYDHYTDKHMVRPTEVQLRPCWSGGAETVVNTAIPQLPTDQGQNIVNPYPVPVQQILPQTATNIIAQQPAQANTTATITPMGDISVVVDATPLFFPNGTQTAVTTVVPLAPPPPPPPAPAPPLQASTVPSAIVDNSNINCTNTTTNTYVEAFPEISANENLVQTTEQTTIPPIPNPNLPTTFGDMQDFIDNTDVAAICTIPADGMPVVDGDDIVIDNNNISLDFDAENLFGEFEEEEEGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKITVARSNKETIQVDVNKDPMLMCAKCPFECESDADMKKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIELTGPAATIPSPSQTETNAVANEIVPLNNAVDATAEKEADTPVAAPVPDDTAMVPVAADTSMGAAAAANAGIDGINVTECETTDTLVQSEKEAEGEAAAATVEENEPAALSTANSEPSTLEVKPTEVTTAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTIFNTPTHFDFDYDFMGDSTSTPNGNINTPNPDSNNTNPSSTTTTTNNNNNNNNNNTTTTDGYTPAAEELPSHVLNGSDKLLTAATMEPSPIKDGRTRLPRTPIFVCKLCNKTFDELSKLVKHETEMHSGGEPRRVAFQHKCSTCHATFRTLTLLKFHMKRHLARRFQCNRCPKCFIKKPELERHILMKHAEKHDTSSKDKAFRCSLNGCTKTFNFKHHMVRHQNAVHLKVRHICNICEKEMINSFNLRVHMRIHRGNGQSYKCPNCDKTYVRRGPLRLHARQAHQLELTESDWAGMLCNNVRSNSLHVKKPSRKKKTSEAPAGD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00571373;
- 90% Identity
- -
- 80% Identity
- -