Dwil012583.1
Basic Information
- Insect
- Drosophila willistoni
- Gene Symbol
- Hivep1
- Assembly
- GCA_018902025.1
- Location
- JAFEWB010000695.1:707371-715096[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.00013 0.011 16.3 0.5 1 23 212 234 212 234 0.98 2 8 0.00021 0.017 15.7 3.3 1 21 240 260 240 264 0.90 3 8 0.0044 0.36 11.5 0.1 1 19 612 630 612 633 0.93 4 8 2.1e-06 0.00018 21.9 2.0 1 23 1350 1372 1350 1372 0.99 5 8 8.3e-06 0.00068 20.1 3.2 1 23 1378 1402 1378 1402 0.92 6 8 2.1e-05 0.0017 18.8 3.6 2 23 1860 1881 1860 1881 0.98 7 8 0.00062 0.051 14.2 1.2 1 23 1887 1911 1887 1911 0.91 8 8 0.002 0.16 12.6 2.7 1 23 1932 1956 1932 1956 0.92
Sequence Information
- Coding Sequence
- ATGGTTGTCGATGGTGACCATCAACAAACAACAACAACAGCAACAACAGATGTTGGCAATATCAATAGCATCGAATCGGCCGGCACAATTGCCGCCGTCGCTGCCGATTGGACCCAAAATTCAAGATATTTGCATAAGAAATTTAAACGTTTGGCCAGTTCAACTGAAGCTGAAAGTGCCAGCAGTACAACCAGCAATAGCAGTAATCAAAGTACTGGTGCTGCTGGTGGTCCAAGTGGCCCTGGTGGCATCTGTGATGCCATGCGTACCACAAGTCTATCATCAAATAGCTCACTCTCACCCCAGCCAATAATTGTGAATGGAGGGCAAACCGCAGCAGCAACATTGAGTGAATTCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATGAGGATATGATCAGTAATAATAATATGATTAGCGTTAAAAGTGCTGGCATTTTTAATGCGAATCATCCACCAAGCCCACGTACACCGCTTAGTCAAAGTAATGGCACCACTGGCTTAGGTTTAACACCGGCAACATTTGCCCAACATCAGCAACAGACACAACCAACAGCGGCCCCAGCAGCAACGGCACCACCATCAGTGCCAACAACTGGCGAAAAGCCAGGCCGTTACACTTGTCCATATTGCAATTTGATTTGTGCCAAGCCATCAGTACTGCAAAAGCATATACGTGCCCATACCAATGAGCGTCCATATCCTTGTAATACCTGCGGCATTGCCTTCAAGACCAAAAGCAATCTCTACAAGCATTGTCGCTCCCGATCGCATGCGGCTCGTGCCAGGGGTATAGAAGTCCCAGTCGATGCAGATGATGGTCTATCCGATCAGGATGTAGACAATGAGCTAAGCAACAGTAGCTCCGAATTGTTGCCGCCGCCATCACGTGCTAATGCCACAACGGCAACAGTTCCACTGGCAGCACCTGTCAATTCCTTGCCATCAGCTAATCGAAGTACATTTGCCAGTGCCAGCGGTGGCATGCAAGTGAATGTGGAAAAGGTGCAAGAGCATATATCGAAATTGATATCACAGAATGAGGCCATAGTTGAGAATAAGGAGATTCTATTGCAAAAGAAATATCCCAAGCAATTGAATCGTTCGCGTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATCGCCTTTAAATATGCAACAATTGCAATATCGTCAAGATCCGGCAACACCCATCAGTAAATTGGAAATACCAAATGCCAACAATAATCATGTGATGCCCTTGAATTTGTCCAGCAAGGCTAAGCCAAATAATATAGCCACACTAGCAGCAGCCGCACCACCCGCACCAGCAACAATTGTTGTTCCATCAACGGCAACGACTCCACTTGTTGCTCCTGTGGCCAGCACTTCCAAATCGGCAACTGCGGCAAATGTCAATAATTCCATTATTAAGAATCTTTTGCTCAATGCACGCGGTTTGGCTGTGCCCATTGGTGAGGGCGATGATGCTGTCTATTCGTGTCCCATTTGCACTAATGAATTCCGCAGTGCGGATGAATTAAAATTGCATAACAGTACCTATTGCCAGGATGCCAGTTCAAGTGCACCCATGAGTCCGGCCTCATCGCCAAGTACGAAATATTTTCGTTCCAATTCGATTACGCTGAGTTTGGCAGAGGTTAAGTCACATATGGCCAATTCAAAGAATCCATTGTCATTGGCTAAATTGGCATGGTCACAGTTAAAGACAAAGCCAAGTAGTTTGGTCTTGAGTCGTTTAAGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTTGTCGTCGATTCTTTACGCTTTGTGGATACTCCTTTACCCTCGCCGGGTCCTTTGCTTGGTAAAACTCCTCTGGTGGATTATAATCAACAAAGTGCCTCAAGACTGGGCTCCCAAGATGCTCAAGTAGTGATAACTAAAATGCATGAGGATCGTCAATTTGAAAATGATGCCAAAAGACCAAAAATGAGTAATGATTCATTTAATTTTCCCACCTTAATGTTTGCCAGCAGCGGCAGCAGCAATCACAACAACAACAACAACATGGAACCACAATCTAGTAAAGAGGAACGCCTAAGACGTTTCACCTCTTCAGGTGGCTCAATGATTCCACTCTCCGAGTGTCCGGAATTGGATAAAAGTCCCAAAATTATACGTACACCACTTTTATCCGGTGGCAGCTTTCAAGAAATGTCACCCAGCAGCAAGGAACGCAAATTGCTGACAACAACGACAACAACGAGTGCTCAACATTTTCAATTTCCACCAATTAATTCCATCACCGCCTTCAATCCATTGACATTGCCACCCATGACAATAGAGAAATCATCGTTATCATCATCATCATCATCAGGTGGTATACCCTATGTGCCGGGTATACCAGGACCGAGTAGCCTAACGCCACAAATGAATTTATTGCCACCGCCGCCACAACAATTGCAGTTGCCATTGCCAGGACAACGACAACGTAGTCCAAATCGTAAGCAACCAAGTCCATTGCTCGGTGGTGCTCTCTCCCCCTTTGGCGGAGTCCAAAATGTGCCCAGTGAGTTTAGCCGACAGCCACCAACACCAGCACAGAGGAATGCCATGCAATGGAATAAGGATGTGGCAGCCAAAAAGGCTCCATTCAATTTTTTAAGAATGGCCGATAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTAATTTTGATAATCTGCAGGCGACAACAAGCAACACCAACAACAAGGAACCCCTAACGCCTCTGCACATAGAAACGCCCAATGGCAATGCAGAGGAGATGCAGCCTCAAACCTTGCCAGCCAAGACGAAATTTTTACGTCCCACTAGTTTGCCACTGAAACCGGGAACATTTACGCCAAAACGTCATCATGGCATCACACCAACGGCCAATACATTGCCTCTGATATCACCAGAGACGCCACGGCCATCGAAATCATGTGTTCAACTCTATTTAAATGGCCATGCCTATACGTATTTGGGTTTAAAATGTAGTACGAAAATGTTTTACTGTACAGTGAATTGTCCGCAACCTTCGTATGTGGCCGATATGCATAAGCTGTCCATGTACAGTGTTTGGCAAGTCTGTGAGGAGAATCAGCCGCATCCTTTGGGCTTCAAATTGAAGCAAGTGATGTCGCTCTATGATTCGCGTCAAAGGATGTTGGGTAATGGTTGCTCAACCACCTCAATGGCCGGGAAATTGAGCTATACTCAGGTCTATTCACAGCAAACTGTTAGCACAGTATCAACAACAAAGCCAAGTAGTTCGTTCTATCAGCATCCATTGAAGCAATTGCCAGCACCGCCATCGCTAACCAATACCTCAAGCACATCTCCTGCAATCACATCCACAGTGGGTGCTTTGAGTGAGGCCAATGTGGCGGCCAAGGCGGCAAGTGAAGATGCGGCAACGGCCAAGAAATTGCAAGAGGGACAACAATTGGTTGGTGGCTATGAATCGCATGAGGATTACACTTATATACGGGGACGTGGACGCGGACGTTATGTGTGCTCGGAATGTGGCATACGCTGCAAGAAGCCATCGATGCTTAAAAAGCATATACGTACCCATACAGATGTGCGTCCATTTACCTGCAGTTTATGCAATTTTAGCTTCAAGACCAAGGGAAATCTTACGAAGCATATGCAATCGAAAACTCATTTCAAGAAATGCAGCGGCGGTGAATTTCTTGATGCCGATGTGGACTTTGATCAGCAATCATCCACTTCGGCTGGTGGACGAACTTCATCAATGGCTGGTGAATCGGATTCCGATGATTATAGTGACAATGAATCGGAAAGTAGTGATACTGATGAATCCAAGTCACGTTTGAAAGAGCATGAGGCGGCCCGGTGTCTGCTCTCGCTATCCATGACTCCACCAATACCACAAAGTGTCTCACCATATTCACAAACTCAAGATGCTTCACAGCCAGCACCAGCGGCGAGTCCAGCTAATAGCATTGGTTCCACAGGATCACAACCGAAGCGTTTGGTTTGTTCATTTACATCGCCAAAGCCGCCATTTGATTATCAGAAACAGGAACAGTATTATTCCAATCCAGAGGAATCCAAACCGAAAGGAAGTTTGGCTAGCGATGAGAGTGCTCCAATGGATTTGACCAAGCCACGGCCAAGCTCTAGCTCCAACAACTCCATCAACAATTCCAATCATCAGCCAAGCAGCAATCATCAACATCATCATCACCATCCTCATCATCAGGCTATGCAAGATTTGCCCAAATCTCAGGCCCAACAGATAAGGGAAGTGATTTTCGGGACATCGGCCAATGAGAGTGGATTCATGAAGACTTTAATATCGGTTTCCGATAAAGTGCGTATATCAGCAGAAATGGAAGAGCAAGTGAAACTGAATGCAGCCGAAAATGAAGGTGAAGATTTGCTACTTCAAACCTATATAAAGGAGCAGGCTCTGCAGCATGCAAAAATGAAGCAGAGTCAATTTAGTCGCAGTTATCAAATAAATGTGACAACTACCAGTACGACTAGTTCAAGCAGTAGTCGTCCTGTGATGAGTATCAAAGAATTGCCCACCATAGAGGTTAATGAGGTGAAGACACCAGATGAGAGTCCCCCGACAGCCACAACCACAAGAGCGGTAACTCCTCCTCCTCATTCTGCTGCTGCTCCTGCTCCCGCCTTAGAAGCCATTGAAAGTGAGGAAATGGAAACGCCAGCTGAGGAAAAGAAAAACGATGAACAGCCTGTAACATCAACAACAGCAACTGCAGCAACAACAACAACGGATATTCCTACACATAATGCCAATTTACCAGCAGCTGTGCAACAACCAGATGCTACAGATTTTAAAGGCGTACTCACTAGTAGCTCTTCCACGGTTACATCCACTTCCAGTGGACCAACGACGCCACTCACACGTCCAGTGATTCGGGGTGATGATAAATTCAAGCCTGCCGATTTACCTGTTAGTAGTACGGTGAGCAATGCCTCTGCATTTCCTCAACGTGTGGTGGCTCCACCACCGCCACCCATTGCCAGCGATGCTCGCCCTACCTGCAACATTTGCCAGAAAACTTTCCAGCGCCAGCATCAACTCACTCTCCATATGAATATCCATTATATGGAACGCAAATTTAAATGTGAACCCTGCAGCATTTCGTTTCGCACTCAGGGCCATCTCCAGAAACACGAACGTTCCGAGGCCCATAAGAATAAAGTGATGATGACATCGACTTTTGGTGTGCCAACCACCTCAAATCCGCGACCCTTCGAGTGTACCGACTGTAAGATAGCCTTTCGAATTCATGGCCATTTGGCCAAGCACCTGAGATCAAAGACTCATGTCCAGAAATTGGAATGCCTACAGAAATTGCCATTCGGCACCTATGCAGAGATCGAACGGGCTGGCATTAGTCTAACCGAAATCGATACAAGCGATTGTGAAAATTCGTTAATCTCATTGAAATTGCTGGCCCAAAAGCTGCTTGAAAAGGACCCGAATAAGCTAAGTGGTTACACATCCCCCTCGGGTATGGCCCAGGACAGTGCCTCCGAAGATGGTTTCAGTGCGGCAAATAGTGCTGCTGCCTCGGCAATTGCCTCATTGGATAATGATAGCGCTGGCAATACACCGCAGCGAGCTAGTTCCATGTCCGAGGATGAGACAGTGACCACTCAGCAGAGCCTAAAACGTCGTCTGCCCGCCACTAGTTTCAGCAGCAATGGCGAAGAGAGTGACAATCCTCAGGAAAATGGTGGTGGTGGCAATGAAAAGCGCGCAAGACCTCAGGACTTAACTGCAGCCACTGCAGCAGCAAGCAACTGA
- Protein Sequence
- MVVDGDHQQTTTTATTDVGNINSIESAGTIAAVAADWTQNSRYLHKKFKRLASSTEAESASSTTSNSSNQSTGAAGGPSGPGGICDAMRTTSLSSNSSLSPQPIIVNGGQTAAATLSEFXXXXXXXXXXXXXXXHEDMISNNNMISVKSAGIFNANHPPSPRTPLSQSNGTTGLGLTPATFAQHQQQTQPTAAPAATAPPSVPTTGEKPGRYTCPYCNLICAKPSVLQKHIRAHTNERPYPCNTCGIAFKTKSNLYKHCRSRSHAARARGIEVPVDADDGLSDQDVDNELSNSSSELLPPPSRANATTATVPLAAPVNSLPSANRSTFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSPLNMQQLQYRQDPATPISKLEIPNANNNHVMPLNLSSKAKPNNIATLAAAAPPAPATIVVPSTATTPLVAPVASTSKSATAANVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICTNEFRSADELKLHNSTYCQDASSSAPMSPASSPSTKYFRSNSITLSLAEVKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVVDSLRFVDTPLPSPGPLLGKTPLVDYNQQSASRLGSQDAQVVITKMHEDRQFENDAKRPKMSNDSFNFPTLMFASSGSSNHNNNNNMEPQSSKEERLRRFTSSGGSMIPLSECPELDKSPKIIRTPLLSGGSFQEMSPSSKERKLLTTTTTTSAQHFQFPPINSITAFNPLTLPPMTIEKSSLSSSSSSGGIPYVPGIPGPSSLTPQMNLLPPPPQQLQLPLPGQRQRSPNRKQPSPLLGGALSPFGGVQNVPSEFSRQPPTPAQRNAMQWNKDVAAKKAPFNFLRMADNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFNFDNLQATTSNTNNKEPLTPLHIETPNGNAEEMQPQTLPAKTKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVADMHKLSMYSVWQVCEENQPHPLGFKLKQVMSLYDSRQRMLGNGCSTTSMAGKLSYTQVYSQQTVSTVSTTKPSSSFYQHPLKQLPAPPSLTNTSSTSPAITSTVGALSEANVAAKAASEDAATAKKLQEGQQLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSLCNFSFKTKGNLTKHMQSKTHFKKCSGGEFLDADVDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYSQTQDASQPAPAASPANSIGSTGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKGSLASDESAPMDLTKPRPSSSSNNSINNSNHQPSSNHQHHHHHPHHQAMQDLPKSQAQQIREVIFGTSANESGFMKTLISVSDKVRISAEMEEQVKLNAAENEGEDLLLQTYIKEQALQHAKMKQSQFSRSYQINVTTTSTTSSSSSRPVMSIKELPTIEVNEVKTPDESPPTATTTRAVTPPPHSAAAPAPALEAIESEEMETPAEEKKNDEQPVTSTTATAATTTTDIPTHNANLPAAVQQPDATDFKGVLTSSSSTVTSTSSGPTTPLTRPVIRGDDKFKPADLPVSSTVSNASAFPQRVVAPPPPPIASDARPTCNICQKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTSPSGMAQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETVTTQQSLKRRLPATSFSSNGEESDNPQENGGGGNEKRARPQDLTAATAAASN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00612302;
- 90% Identity
- -
- 80% Identity
- -