Dtro002032.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila tropicalis
Gene Symbol
Hivep1
Assembly
GCA_018151085.1
Location
JAECWH010000574.1:10529181-10537215[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00013 0.01 16.3 0.5 1 23 189 211 189 211 0.98
2 8 0.00021 0.016 15.7 3.3 1 21 217 237 217 241 0.90
3 8 0.0044 0.34 11.5 0.1 1 19 648 666 648 669 0.93
4 8 2.1e-06 0.00017 21.9 2.0 1 23 1380 1402 1380 1402 0.99
5 8 8.3e-06 0.00064 20.1 3.2 1 23 1408 1432 1408 1432 0.92
6 8 2.1e-05 0.0016 18.8 3.6 2 23 1875 1896 1875 1896 0.98
7 8 0.00062 0.048 14.2 1.2 1 23 1902 1926 1902 1926 0.91
8 8 0.002 0.15 12.6 2.7 1 23 1947 1971 1947 1971 0.92

Sequence Information

Coding Sequence
ATGGAAAATGAAACATCTACAGCAACGACAACAACAAAGCATTATAAGAGCACAGCCAAACAATATAAAACACAAAAAAAATTTAAACGTTTGGCCAGTTCAACTGAAGCAGAAAGTGCCAGCAGTACGACCAGCAATAGCAGTAATCAAAGTACTGGTGGTGCTGGTGGTGCAAGTGGCGCTGGTGGCATCTGTGATGCCATGCGTACAACAAGTCTATCTTCAAATAGCTCGCTCTCACCCCAGCCAATAATTGTGAATGGAGGGCAAACCGCAGCAGCAACATTGAGTGAATTCAGTGCCAATCATCTTAATAATCATCATCAGCATCAGCATCATGAGGATATGATGAGTAATAATAATATGATAAGCGGTAAAAGTGCTGGCATTTTTAGTGCGAATCATCCACCAAGGACACGTACACCGCTCAGTCAAACTAATGGCACCACTGGCTTAGGTTTAACACCGGCAACATTTGCCCAACATCAACAGCAGACGCAACCAACAGCAGCCCCAGCAACGGCATCACCATCAGTGCCAACAACTGGCGAAAAGCCTGGCCGTTACACTTGTCCATATTGCAATTTGATTTGTGCCAAACCATCAGTACTGCAAAAGCATATACGAGCCCATACCAATGAGCGTCCATATCCCTGTAATACCTGCGGCATTGCCTTCAAGACCAAAAGCAATCTCTATAAGCATTGTCGCTCCCGATCGCATGCAGCTCGTGCCAGGGGTATAGAAGTCCCAGTCGATGCAGATGATGGTCTATCCGATCAGGATGTAGACAATGAGCTAAGCAACAGTAGCTCCGAAGTGCCTAGTCGCTCTGGTTCACCGTACGAAGAGCTGAATATAACATCATCGCCCTCGCCCTCACCATCTACATTGTCGGCTGCCAAAAGTGCCTACTTGCAACAGCAGCAGCATATGCAACAATTGCCATTGGGTTCACCGGCAGCTGGTACATTGCCACCATTACAGGATAATCTATTGCATACATCAACGGCCAATACATCAGCCCAGCAACCACCTGTCAATTCCTTGCCATCAGCTAATCGAAGTACATTTGCCAGTGCCAGCGGTGGCATGCAGGTGAATGTGGAAAAGGTGCAAGAGCATATATCGAAATTGATATCACAAAATGAGGCCATAGTTGAGAATAAGGAGATTTTGTTGCAAAAGAAATATCCCAAGCAATTGAATCGTTCTCGGAGTTTTAATAATGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATCGCCTTTAAATATGCAACAATTGCAGTATCGTCAAGATCCGGCAACACCCATCAGTAAATTGGAATTACCAAATGCCAATAATAATCATGTGATGCCCTTGAATTTGTCCAGCAAGGCTAAGCCAAATAATATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATCAACGACAACGACTCCACTTGTTGCTCCTGTGGCCAGCACTTCCAAATCGGCGACAGCGGCAAATGTTAATAATTCCATTATTAAGAATCTTTTGCTCAATGCACGCGGTTTGGCTGTGCCCATTGGCGAAGGCGACGATGCTGTCTATTCGTGTCCCATTTGCACTAATGAATTCCGCAGTGCGGATGAATTGAAGTTGCATAACAGTACATATTGTCAGGATGCCAGCTCAAGTGCTCCCATGAGTCCGGCCTCATCGCCAAGTACAAAATACTTTCGTTCCAATTCGATTACGCTGAGTTTGGCAGAGGTTAAGTCACATATGGCCAACTCGAAGAATCCTTTATCATTGGCTAAATTGGCATGGTCACAGTTAAAGACAAAGCCAAGTAGTTTGGTCTTGAGTCGTCTAAGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTTGTTGTCGATTCTTTACGCTTTGTGGATACTCCTTTGCCCTCGCCTGGTCCTTTGCTTGGCAAAACTCCTCTGGTGGATTACAATCAACAAAGTGCCTCGAGACTGGGCTCCCAAGATGCTCAAGTCGTGATAACTAAAATGCATGAGGATCGTCAATTTGAAAATGATGCCAAAAGACCAAAAATGAGTAATGATTCATTTAATTTTCCCACCTTAATGTTTGCCAGCGGCAGCAGCAACCATAACAACAACAACAACTTGGAACCGCAATCTAGTAAAGAGGAACGCCTAAGACGTTTCACCTCGTCAGGTGGCTCAATGATTCCACTCTCCGAGTGTCCGGAATTGGATAAAAGTCCCAAAATCATACGTACACCGCTTTTATCCGGTGGCAGTTTTCAAGAAATGTCACCCAGCAAGGAACGCAAATTGCTGTCAACAACAACGAGTGCTCAACACTTTCAATTTCCACCAATTAATTCCATCACCGCCTTCAATCCATTGACATTGCCACCTATGTCCATAGAGAAACCTTCACCATCATCATCAGCTGGTATACCCTATGTGCCGGGTATACCAGGACCGAGTAGCCTAACGCCACAAATGAATTTATTGCCACCGCCGCCACAACAATTGCAATTGCCATTGCCAGGACAACGACAACGTAGTCCGAATCGTAAGCAACCGAGTCCATTGCTCGGTGGTGCTCTCTCCCCCTTTGGTGGAGTGCAAAATGTGCCCAGTGAGTTCAGCCGACAGCCACCAACACCAGCACAGAGGAATGCAATGCAATGGAATAAGGATGTGGCAGCTAAAAAGGCTCCATTCAATTTTTTAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGAACCCCTCACGCCTCTGCACATAGAAACGCCCAATGGCAATGCAGAGGAAATGCAGCCTCAAGCCTTACCAGCCAAGACTAAATTTTTACGTCCCACCAGTTTGCCACTGAAACCGGGAACATTTACGCCAAAACGTCATCATGGCATCACTCCAACGGCCAATACATTGCCTCTGATATCACCAGAGACGCCACGGCCATCGAAATCATGTGTTCAACTCTATTTAAATGGCCATGCCTATACGTATTTGGGCTTGAAGTGCAGTACAAAAATGTTTTACTGTACAGTAAATTGTCCGCAACCTTCGTATGTGGCTGATATGCATAAGCTGTCCATGTATAGTGTTTGGCAAGTCTGTGAGGAGAATCAACCGCACCCATTGGGCTTTAAGTTGAAGCAAGTGATGTCTCTCTATGATTCACGGCAAAGGATGTTGGGTAATGGTTCCTCAACCACCTCTATGGCAGGAAAGTTGAGCTATACCCAGGTCTATTCACAGCAAACTGTTAGCACAGTATCAACTTCAAAGCCTAGCAGTTCGTTTTATCAGCATCCGTTGAAACAATTGCCAGCACCACCATCGATAACCAATGCCACATCCCCCGCAATCACATCCACAGTGGGTGCTTTGAGTGAGGCCAATGTCGCGGCCAAGGCGGCAAGTGAAGATGCGGCAACGGCCAAGAAACTACAAGAGGGACAACAGTTGGTTGGTGGCTATGAATCGCATGAGGATTACACTTATATACGGGGACGTGGACGCGGACGTTACGTATGCTCGGAATGTGGCATACGCTGCAAGAAGCCATCGATGCTTAAAAAGCATATACGTACCCACACAGATGTGCGTCCATTTACCTGCAGTTTATGCAATTTTAGCTTCAAGACCAAAGGAAATCTCACCAAGCATATGCAATCGAAAACTCATTTCAAGAAATGCAGCGGCGGTGAATTTCTGGATGCCGATGTGGACTTTGATCAGCAGAGTTCCACTTCGGCTGGTGGACGAACTTCATCAATGGCTGGTGAATCGGACTCCGATGATTTCAGTGACAATGAATCGGAGAGTAGTGATACTGATGAATCCAAGTCACGTTTGAAAGAGCATGAGGCGGCCCGGTGTCTGCTCTCGCTATCCATGACTCCACCAATACCACAAAGTGTCTCACCATATTCACAAACTCAAGATGCTTCACAACCTGCACCAGCGGCGAGTCCGGCTAATAGCATTGGCTCGACAGGATCACAACCGAAGCGTTTGGTTTGTTCATTTACATCGCCAAAGCCGCCATTTGATTATCAGAAACAGGAACAGTATTATTCCAATCCAGAGGAATCCAAACCGAAAGGAAGTTTGGCCAGCGATGAGAGTGCTCCAATGGATTTGACCAAGCCACGGCCAAGCTCTAGCTCCAACTCCATCAACAATTCCAATCATCAGCCAAGCAGCAATCACCTTCAACATCATCATCCGGCTATGCAAGATTTGCCCAAATCTCAGGCCCAACAGATAAGGGAAGTGATTTTCGGGACATCGGCCAATGAGAGTGGTTTCATGAAGACTTTAATATCGGTTTCCGATAAAGTGCGTATATCAGCAGAAATGGAAGAGCAAGTGAAACTGAATGCAGCCGGAAATGAAGGTGAAGATTTGCTATTTCAAACATATATAAAGGAACAGGCTCTGCAACATGCCAAAATGAAGCAGAGTCAATTTAGTCGTAATTATCAAATAAATGTGACAACTACCAGTACGACTAGTTCAAGCTGTAGTCGTCCTGTGATGAGTATCATAGAATTGCCCACCATAGAGGTAAATGAGGTGAAGACACCAGATGAGAATCCACCGGCAGCCACACCTACAAGAGCAGTAACTCCTCCTCCTTCTCTTCCTGCTCCTGCCATAGAAGCCATTGAAAATGATGAAATGGAAACACCATCTGAGGAAAAGAAAAACGATGATCAGCCTGTAACAACAACCACAACGGATGTTCCCCCACATAATGCCAATTTGCCAGCAGCTGTGCAACAACCAGATGCCACAGATTTCAAAGGCGTACTCACTAGTACCTCTTCCACGGCTACATCCGCTTCCAGTGGACCATCAACGCCACTTACACGTCCTGTGATCCGGGGTGAGGATAAATTCAAGCCTGCTGATCTACCTGTTAGTAGTACTGTGAGCAATGCCTCTGCATTTCCTCAACGTGTGGTGGCTCCACCACCGCCACCCATTGCCAGCGATGCTCGCCCTACCTGCAACATTTGCCAGAAAACTTTCCAACGCCAGCATCAACTCACTCTCCATATGAATATCCATTATATGGAACGCAAATTTAAATGCGAACCTTGCAGCATTTCGTTTCGCACTCAGGGTCATCTCCAGAAACACGAACGTTCCGAGGCCCATAAGAATAAAGTGATGATGACATCGACTTTTGGTGTGCCAACCACCTCAAATCCGCGACCATTTGAGTGTACCGACTGTAAGATAGCCTTTCGAATTCATGGCCATTTGGCCAAGCACTTGAGATCAAAGACTCATGTCCAGAAATTGGAGTGCCTGCAGAAATTGCCATTCGGTACCTATGCAGAGATCGAACGGGCTGGCATCAGTCTAACCGAAATCGATACAAGCGATTGTGAAAATTCGTTAATCTCATTGAAATTGTTGGCACAGAAGCTACTCGAAAAGGACCCGAATAAGCTAAGTGGTTACACATCCCCCTCGGGCATGGCACAGGATAGTGCCTCCGAAGATGGATTCAGTGCGGCAAATAGTGCTGCTGCCTCGGCCATTGCCTCATTGGATAATGATAGTGCTGGCAATACACCGCAGCGAGCTAGTTCCATGTCCGAGGATGAGACAGTGACCACTCAACAGAGTTTAAAACGTCGTCTGCCCGCCACTAGTTTCAGCAGCAATGGCGAAGAGAGTGACAATCCTCAGGAGAATGGTGGTGGCAATGAGAAGCGCGCAAGATCTCAGGACTTAACTACAGCCACTGTAGCAGCAAGCAACTGA
Protein Sequence
MENETSTATTTTKHYKSTAKQYKTQKKFKRLASSTEAESASSTTSNSSNQSTGGAGGASGAGGICDAMRTTSLSSNSSLSPQPIIVNGGQTAAATLSEFSANHLNNHHQHQHHEDMMSNNNMISGKSAGIFSANHPPRTRTPLSQTNGTTGLGLTPATFAQHQQQTQPTAAPATASPSVPTTGEKPGRYTCPYCNLICAKPSVLQKHIRAHTNERPYPCNTCGIAFKTKSNLYKHCRSRSHAARARGIEVPVDADDGLSDQDVDNELSNSSSEVPSRSGSPYEELNITSSPSPSPSTLSAAKSAYLQQQQHMQQLPLGSPAAGTLPPLQDNLLHTSTANTSAQQPPVNSLPSANRSTFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSPLNMQQLQYRQDPATPISKLELPNANNNHVMPLNLSSKAKPNNXXXXXXXXXXXXXXXXXXXXXXXXSTTTTPLVAPVASTSKSATAANVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICTNEFRSADELKLHNSTYCQDASSSAPMSPASSPSTKYFRSNSITLSLAEVKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVVDSLRFVDTPLPSPGPLLGKTPLVDYNQQSASRLGSQDAQVVITKMHEDRQFENDAKRPKMSNDSFNFPTLMFASGSSNHNNNNNLEPQSSKEERLRRFTSSGGSMIPLSECPELDKSPKIIRTPLLSGGSFQEMSPSKERKLLSTTTSAQHFQFPPINSITAFNPLTLPPMSIEKPSPSSSAGIPYVPGIPGPSSLTPQMNLLPPPPQQLQLPLPGQRQRSPNRKQPSPLLGGALSPFGGVQNVPSEFSRQPPTPAQRNAMQWNKDVAAKKAPFNFLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEPLTPLHIETPNGNAEEMQPQALPAKTKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVADMHKLSMYSVWQVCEENQPHPLGFKLKQVMSLYDSRQRMLGNGSSTTSMAGKLSYTQVYSQQTVSTVSTSKPSSSFYQHPLKQLPAPPSITNATSPAITSTVGALSEANVAAKAASEDAATAKKLQEGQQLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSLCNFSFKTKGNLTKHMQSKTHFKKCSGGEFLDADVDFDQQSSTSAGGRTSSMAGESDSDDFSDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYSQTQDASQPAPAASPANSIGSTGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKGSLASDESAPMDLTKPRPSSSSNSINNSNHQPSSNHLQHHHPAMQDLPKSQAQQIREVIFGTSANESGFMKTLISVSDKVRISAEMEEQVKLNAAGNEGEDLLFQTYIKEQALQHAKMKQSQFSRNYQINVTTTSTTSSSCSRPVMSIIELPTIEVNEVKTPDENPPAATPTRAVTPPPSLPAPAIEAIENDEMETPSEEKKNDDQPVTTTTTDVPPHNANLPAAVQQPDATDFKGVLTSTSSTATSASSGPSTPLTRPVIRGEDKFKPADLPVSSTVSNASAFPQRVVAPPPPPIASDARPTCNICQKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTSPSGMAQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETVTTQQSLKRRLPATSFSSNGEESDNPQENGGGNEKRARSQDLTTATVAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00618612; iTF_00571359;
90% Identity
iTF_00571359;
80% Identity
-