Basic Information

Insect: Drosophila willistoni
Gene Symbol: prg
Assembly: GCA_018902025.1
Location: JAFEWB010000714.1:9428904-9430738[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.21 17 6.2 2.5 1 23 219 242 219 242 0.95

2 8 0.0005 0.041 14.5 0.8 1 23 248 271 248 271 0.98

3 8 1.2e-06 9.6e-05 22.8 2.3 1 23 277 299 277 299 0.98

4 8 5.8e-10 4.8e-08 33.2 1.7 1 23 305 327 305 327 0.99

5 8 9.7e-07 7.9e-05 23.0 1.3 1 23 333 355 333 355 0.98

6 8 4.5e-05 0.0037 17.8 2.1 1 23 442 464 442 464 0.96

7 8 1.9e-05 0.0016 19.0 0.5 1 23 469 492 469 492 0.92

8 8 1 85 4.1 3.3 1 23 496 518 496 518 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.21	17	6.2	2.5	1	23	219	242	219	242	0.95
2	8	0.0005	0.041	14.5	0.8	1	23	248	271	248	271	0.98
3	8	1.2e-06	9.6e-05	22.8	2.3	1	23	277	299	277	299	0.98
4	8	5.8e-10	4.8e-08	33.2	1.7	1	23	305	327	305	327	0.99
5	8	9.7e-07	7.9e-05	23.0	1.3	1	23	333	355	333	355	0.98
6	8	4.5e-05	0.0037	17.8	2.1	1	23	442	464	442	464	0.96
7	8	1.9e-05	0.0016	19.0	0.5	1	23	469	492	469	492	0.92
8	8	1	85	4.1	3.3	1	23	496	518	496	518	0.98

Sequence Information

Coding Sequence: ATGCTTAATTTAGCCACGGAAGGAACGGATACCCCGGCCTTTAGCACTGCAAATGGACCTTCGACTAGTGCGGAAGAGGATAACAATGCACGGTGCCGTCTGTGCCACCAAGCGGCAGAGACCGCGGTGAACATTTTTGAGAATGATGTGGATTTCGGTAGCATGGGTAGCATAGCAAATCTCTGCCAGAATTTATACGGCGTGCAGTATGAACGCCATGAATTGCTACCGGAAAGGATATGTTCACGTTGCCTGGAGTTACTTGAGGATTTCTATATGCACCGCAAGGGCATGGAACAGCGGGAGCTAGCCTTACTGGCGGAACTTGGCGAGATGCTGAAACAAGATGCCAAATATCGTCCTGGTCTCAATGGCAATCCTGGTATTTTTGAACCGGAAGAAGGATGCATTATTGTGGATGTCGATCCTGATAAGCTGTCGGAGACAAGCGAAGATGAATTGTATGATGATGACGATGATGAGAATGGAGAAGTCGAAGATGAGGAGGATGAAGAGGAGGAGGACGAGAACATGCAAGCACAAAATGGCGATGAAATGGAGATGCCTTTGGGGATGGACGCCGCGCAGATGGCCTTGATGGGAGCGGCGAATCTATCACAAGACGCGACCATGGACTCACGGCCCAAATGTGCCTATTTGTGCCAGTTTTGCGATTTGGGCTTTACTTTACAATCTGATTGTCAGCAGCACGAAAAGACATCTCATGATGCAGCTGCTCCATATAGTTGCAGCTATTGTAACTTGCGTATGACAACTAGACCTCAATTGATTACCCATATTAAGACACTTCATGATGCTGACCGACCCTATGTCTGTGCCCATTGTCGCAAGAGCTTCGTGCGACGCTCAGATTTAAAGAAACACACTATAGTTCATACTGGCGTGCGTCCCTATACCTGCAGTGTGTGCGGCAAGAGCTTTTCCCGCAACACTAATCTGACCAAACATATGCGCATTCACAGCGGTGTAAAGCCATTTGTGTGCCAGCAATGTCCACGCTCTTTCCAAACGTCTTCGGAGATGATGAAGCATATGCGTTCCCATGCTGAGATCAAACCTTTCCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATGCTACAAAATTATCTTTACCAACAAACCGACTTTACTCCGAATAAAGTTAAACCTCCTGCACAGTCAAAATCATCACGTAATTTTCATTGTGATGTCTGCGACAGGAGTTTTCAGCGCGAAAGAGATCTACAGCGGCATCGGGCTCTTCACATGGATACGCTCTTCTCCTGTAAAATCTGTCAACAGGGTTTCAATCGTCGCGAACAGCTGCAACGTCATGAGCTTGAGGCTCATGGCCCTAGCTACACCTGTGGCGTTTGTTGCATTAGTTTTTTGCATCAAACGGAACTGGAGAATCATTTTAAAGTTCATCAACTTCAACATCAGATGGCCAAAAGTACTCAGGAGGCTATGAATGTGGCTGCCGTGCAGACAGCTGCAGGCAATGTTCTACCCATTCCCGTTTCCATGCCAATGATGCCCGTGGAGCAGGCACAACTACGTCCTTCAGCCGCAGATATTCATTTTTATAGCAACATGATACCCACTATGAATTTAGGCTTCTATAATGAAACCCGACCGGAAGAATAA
Protein Sequence: MLNLATEGTDTPAFSTANGPSTSAEEDNNARCRLCHQAAETAVNIFENDVDFGSMGSIANLCQNLYGVQYERHELLPERICSRCLELLEDFYMHRKGMEQRELALLAELGEMLKQDAKYRPGLNGNPGIFEPEEGCIIVDVDPDKLSETSEDELYDDDDDENGEVEDEEDEEEEDENMQAQNGDEMEMPLGMDAAQMALMGAANLSQDATMDSRPKCAYLCQFCDLGFTLQSDCQQHEKTSHDAAAPYSCSYCNLRMTTRPQLITHIKTLHDADRPYVCAHCRKSFVRRSDLKKHTIVHTGVRPYTCSVCGKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTSSEMMKHMRSHAEIKPFQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLQNYLYQQTDFTPNKVKPPAQSKSSRNFHCDVCDRSFQRERDLQRHRALHMDTLFSCKICQQGFNRREQLQRHELEAHGPSYTCGVCCISFLHQTELENHFKVHQLQHQMAKSTQEAMNVAAVQTAAGNVLPIPVSMPMMPVEQAQLRPSAADIHFYSNMIPTMNLGFYNETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00571350; iTF_00612251; iTF_00523864;
90% Identity: iTF_00571350;
80% Identity: -