Basic Information

Insect: Drosophila tropicalis
Gene Symbol: prg
Assembly: GCA_018151085.1
Location: JAECWH010000378.1:3636220-3638060[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.36 28 5.5 1.4 1 23 220 243 220 243 0.94

2 9 0.0005 0.039 14.5 0.8 1 23 249 272 249 272 0.98

3 9 1.2e-06 9.1e-05 22.7 2.3 1 23 278 300 278 300 0.98

4 9 5.8e-10 4.5e-08 33.1 1.7 1 23 306 328 306 328 0.99

5 9 9.7e-07 7.5e-05 23.0 1.3 1 23 334 356 334 356 0.98

6 9 4.9e-05 0.0038 17.7 0.7 1 23 362 384 362 384 0.98

7 9 2.5e-05 0.0019 18.6 2.1 1 23 444 466 444 466 0.96

8 9 1.9e-05 0.0015 18.9 0.5 1 23 471 494 471 494 0.92

9 9 1 80 4.0 3.3 1 23 498 520 498 520 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.36	28	5.5	1.4	1	23	220	243	220	243	0.94
2	9	0.0005	0.039	14.5	0.8	1	23	249	272	249	272	0.98
3	9	1.2e-06	9.1e-05	22.7	2.3	1	23	278	300	278	300	0.98
4	9	5.8e-10	4.5e-08	33.1	1.7	1	23	306	328	306	328	0.99
5	9	9.7e-07	7.5e-05	23.0	1.3	1	23	334	356	334	356	0.98
6	9	4.9e-05	0.0038	17.7	0.7	1	23	362	384	362	384	0.98
7	9	2.5e-05	0.0019	18.6	2.1	1	23	444	466	444	466	0.96
8	9	1.9e-05	0.0015	18.9	0.5	1	23	471	494	471	494	0.92
9	9	1	80	4.0	3.3	1	23	498	520	498	520	0.98

Sequence Information

Coding Sequence: ATGCTTAATTTAGCCACAGAAGGAACAGATACCAGGGCTTGGAGCACTGCAATTGAGCCTTCGACTAGATCCGAAGAGGATTGCGATGCACGCTGCCGTCTGTGCCACCAAGCTGCAGGAACCGCAGTAAACATATTTGAGAATGATGTGGATTTCGGTAGCATGGGTAGCATAGCAAATCTCTGCCAGAATTTATACGGCGTGCAGTACGAACGCCATGAATTGCTACCGGAAAGGATATGTTCACGGTGCCTGGAGTTATTGGAGGATTCCTACATGCACCGCAAGGGCATGGAGGAGCGGGAGCTAGCCTTGCTCGCGGAACTTGGCGAGATGCTAAAACAGGATGCCAAATATCGTCCTGGTCTCAATGGCAATCCTGGTAATTTTGAGCCGGAAGAAGGCTGCATTATAGTGGATGTAGATCCTGATAAGCTGTCGGAGACAAGCGAAGATGAATTGTATGATGATGACGATGATGAGAATGGAGAAGAAGTCGAAGATGAGGAGGATGACGAGGAGGAGGACGAGAACATGCAAGCACAGAATGGCGATGAAATGGAGATGCCATTGGGCATGGACGCAGCCCAGATGGCCTTGATGGGAGCGGCGAATCTGTCACAGGACGCGACCATGGACTCACGTCCTAAATGTGCCTATTTGTGTCAGTTTTGCGATCTGGGCTTTACCTTAGAATCTGATTGTCAGCAGCACGAGAAAACAGCTCACGATGCAGCTGCTCCATATAGTTGCAGCTATTGTAACTTGCGTATGACAACTAGACCTCAATTGATTACCCATATTAAGACATTGCATGACGCTGACCGACCCTATGTCTGTGCACATTGTCGCAAGAGCTTCGTGCGACGCTCTGACTTAAAGAAGCACACTATAGTTCATACAGGCGTGCGTCCCTATACCTGCAGTGTGTGCGGCAAGAGCTTTTCCCGCAACACCAATCTGACCAAACATATGCGCATTCACAGCGGTGTAAAGCCATTCGTGTGCCAGCAGTGTCCACGCTCTTTCCAAACGTCTTCGGAGATGATGAAGCATATGCGTTCTCATGCTGAGATCAAACCTTTTCAGTGTCAGCGCTGTCCGTATTCATCATCGCGTAAGGACAAACTGGTGGCCCATCAGCAAGTGCACAATAAACGTGACGTTGAGCAGCAGCAACAACAGGGCCAGGCTCAGCTGCAGCCACAAATGCAACCACAACTGCAGCCCCAACTCCAACCGCACATGCTACAAAATTTTCTTTACCAACAGACCGACTTTACTCCGACTAAAGTCAAACCTTCTGGCCAGTCTAAATCATCACGTAATTTTCATTGTGATATCTGCGACAGGAGTTTTCAGCGCGAAAGAGATCTACAGCGGCATCGGGCTCTTCACATGGATACGCTCTTCTCCTGTAAGATCTGTCAACAGGGTTTCAATCGTCGGGAACAATTGCAACGTCATGAGCTTGAGGCTCATGGCCCTAGCTACACCTGTGGCGTTTGTTGCATTAGTTTTCTGCATCAAACGGAACTGGAGAATCATTTTAAAGTTCATCAACTTCAACATCAAATGGCCAAAAGTACTCAGGAGGCTATGAACGTGGCTGCCGTGCAGACAGCTGCAGCCAATGTTCTACCCATTCCCGTTTCCATGCCAATAATGCCCGTGGAGCAGGTGCAACTACGTCCTTCAGCCGCAGATATTCATTTTTATAGCAACATGATACCCACAATGAATTTAGGCTTCTATAATGAAACCCGACCGGAAGAGTAA
Protein Sequence: MLNLATEGTDTRAWSTAIEPSTRSEEDCDARCRLCHQAAGTAVNIFENDVDFGSMGSIANLCQNLYGVQYERHELLPERICSRCLELLEDSYMHRKGMEERELALLAELGEMLKQDAKYRPGLNGNPGNFEPEEGCIIVDVDPDKLSETSEDELYDDDDDENGEEVEDEEDDEEEDENMQAQNGDEMEMPLGMDAAQMALMGAANLSQDATMDSRPKCAYLCQFCDLGFTLESDCQQHEKTAHDAAAPYSCSYCNLRMTTRPQLITHIKTLHDADRPYVCAHCRKSFVRRSDLKKHTIVHTGVRPYTCSVCGKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTSSEMMKHMRSHAEIKPFQCQRCPYSSSRKDKLVAHQQVHNKRDVEQQQQQGQAQLQPQMQPQLQPQLQPHMLQNFLYQQTDFTPTKVKPSGQSKSSRNFHCDICDRSFQRERDLQRHRALHMDTLFSCKICQQGFNRREQLQRHELEAHGPSYTCGVCCISFLHQTELENHFKVHQLQHQMAKSTQEAMNVAAVQTAAANVLPIPVSMPIMPVEQVQLRPSAADIHFYSNMIPTMNLGFYNETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618604;
90% Identity: iTF_00523864;
80% Identity: -