Dwil009274.1
Basic Information
- Insect
- Drosophila willistoni
- Gene Symbol
- su(Hw)
- Assembly
- GCA_018902025.1
- Location
- CM032166.1:25877518-25880653[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00061 0.05 14.2 2.2 1 20 243 262 243 264 0.94 2 12 2.5e-06 0.00021 21.7 0.4 3 23 315 336 313 336 0.93 3 12 1.2 95 3.9 0.0 1 23 342 364 342 364 0.91 4 12 5e-07 4.1e-05 23.9 2.4 1 21 371 391 371 392 0.95 5 12 5.1e-06 0.00042 20.8 0.8 2 23 404 425 403 425 0.96 6 12 9.5e-05 0.0078 16.8 5.3 1 23 436 458 436 458 0.99 7 12 7.4e-05 0.0061 17.1 0.9 1 23 464 486 464 486 0.97 8 12 8.6e-06 0.0007 20.0 0.7 1 23 492 514 492 514 0.98 9 12 1.9e-06 0.00015 22.1 2.2 1 23 520 542 520 542 0.97 10 12 2.1e-05 0.0017 18.8 0.5 1 23 546 568 546 568 0.96 11 12 2.3e-05 0.0019 18.7 0.3 1 21 576 596 576 600 0.93 12 12 7e-06 0.00057 20.3 0.4 3 23 620 641 618 641 0.97
Sequence Information
- Coding Sequence
- ATGAATACCTCCAAGGAGGGTCAAAAATGGGAGAAAGAGACTGTAGTGAAAATCGTGGATCTCGATGAAGTTAGATCGCCGACCAAGGACAATAAACGCCCGTCTACACGTATGAAATTGCTGAACGATGTAACAGGATCGACCAAAACTGCGTCAAGTGGAAAGCCGGAAAAGCGTTCTGCAGCAGCAGGAGGAGGTGCAGTCATTAAAATACTCAACGATGATACAAACACACCCGTTAGAGCAGAGAAACGCACAAGCGGAGGCAGCAAAAAGACAATTAGTCCCACTGTGCCGGCACCAGCGGCTGTAAAGATTCTTAACGATAAGCGATTCGCCTCACCAGTCATGGAAACGGTAAAGATTAAGGCCAATCCCAGCAAGAAAAAGAAAATGGATCACTATGTACTCGAATCGGTTAAAAATGAAAACAGTAAAGCTCCGCCGGACGTCACAGCCAAAGTTGTCGTCCAGAACGATGACGAAGATGATGATGACGATGATGGAGCCATTGCCTTTATTCTGGCCGACGTCGACGAGGATGAGGAGGGTGATGACCAGGAGGCGGTGGCACGTAATAATGGCACAAAAATTGTGGTATCCCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGCGATGAGAGTCGAGTGGTCACTGGTGGCCACAATACATCGGGCAATCAGAATAGCATCAAGGAAATTGTGGAGCATGTCTGCGGCAAATGCTACAAGACATTCCGTCGCGTGAAGAGTCTGAAAAAACATTTGGAATTCTGTCGCTATGACAGTGGCTATCATCTTCGCAAGGCGGATATGTTAAAGAACATTGAGAAGATCGAAAAGGATGCGGTGGTCATGGAGAAGAAAGATATATGTTTCTGTTGCAACGAAAGCTACGACACTTTCCATCTGGGTCATATCAATTGCCCGGATTGCCCAAAGTCTTTTAAGACACAGACCAGCTATGAGCGGCACATATTCATCACTCACTCTGAGTTCAATACGTTTCCCTGTTCCATTTGCAATGCAAATTTACGCAGCGGACCTCTTCTGACGCTGCACGAGGAGCAGCACAAGAATCGCGGCAAGCCCTATGCTTGCAAGATCTGTGGCAAGGATTTCACAAGGTCCTATCATCTAAAGCGACATCAGAAATACTCATCATGCTCGGCCAACGAGACGGACACCATGAGCTGTAAGGTGTGTGATCGTGTATTCTACCGCCTAGACAATTTACGCTCCCATCTGAAGCTGCATCTGGGCACTCAAGTGGTTAAGAAGCCGGAGTACATGTGTCATGTGTGCAAGAATTGCTTCTACAGCTTATCCACACTCAACATTCATATACGTACACATACGGGCGAGAAACCCTTCGATTGTGATTTGTGCGATAAGAAGTTCTCTGCTTTGGTGGCCCTGAAGAAGCATCGACGCTATCACACTGGCGAAAAGCCCTACAGCTGCACAGTGTGTAATCAATCCTTTGCTGTAAAGGAAGTCCTTAATCGTCACATGAAACGGCACACTGGCGAACGTCCACACAAGTGCAACGAGTGCGGTAAAAGCTTCATTCAGGCCACACAATTGCGCACCCATTCCAAGGTTCATTTGCGTCCGTATGCCTGTGATTTGTGCGATGAGAAATTTAAAACCGAGAAGCAATTGGAACGCCACGTCAAGGATCATTCACGACAGAAACGAGCCTCGTTCACTTGCTCCGAATGTAAGCGAAACTTTCGTACTGCTGATTTGCTCAAAGAGCACATGGACGCTGGCGATCATACACCTAAGCCTCAACGCGCCAAGCGCAGTAGCACCAAAATCACTGGACGCACCGATTGCGCCATTTGTGACAAGAATTTCGATAGCACCGATACCCTGCGTAAGCACATACGCACCGTGCACGAATGTGATCCGGACGACATCTTTGGCGTAGATCCACCGGCCGCGAAGCAAAAGAAGAAAGACGACAAGTCTACTGAACTGGTGGATGCAGCAGACGAGGAATCGTCAGTGGGTATAGACCTTAATCCTGCAACCGATTCGCTCGAAGGCAATGGTGTTGTGGTGCGTGAATTCCTCTTGGATGAGGGCGATGGCACCGCTCAAACAATTGTGCTCGAGAATGAGACTTACACCATACTGCCACTGGAAGGCGAAATTGAAGGTGGAGAGGAACCAGCGGGCAGGAAACCCAAAGCAGAATCAAAGAAGAAATCATCCCAGGTTTCGCCTGTCGTTAAGAAGGAACAACGTAAATCCTTGGCTGCCAGTCTGGCTGAGGCCATTGCTGATAAGGTCGATGAAGAGGACTTTACCGGCGAAGTGCTAACCGAAGAGGATGTCAAGCTAAAGGAGAATGTGGCCAAACTGATTGATATGCTAGTGGATCCACCGATATTAAAGAAATACGGCTGGCCCAACACCTCGGAGGAGACGGTGCTTTGCAAGGTCATCGAGAATTGTGGACACGACTTGACCAAGGGTGGCGACAACTATGCAGAAATGGAATATGGCTCACGTATGCGTGAATACTGCAAACTTCTCTTCACTGTAGTCATTCACAATGATTCCATAAAGTCCTTGCTCAACAATTTTCCCATTGACGACGTTATTGAATACGTTCTGGGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTAAGAAGTCAATCAAAAAGTCTGAGGCCGTCGTGAAAGTTAGGATTTAA
- Protein Sequence
- MNTSKEGQKWEKETVVKIVDLDEVRSPTKDNKRPSTRMKLLNDVTGSTKTASSGKPEKRSAAAGGGAVIKILNDDTNTPVRAEKRTSGGSKKTISPTVPAPAAVKILNDKRFASPVMETVKIKANPSKKKKMDHYVLESVKNENSKAPPDVTAKVVVQNDDEDDDDDDGAIAFILADVDEDEEGDDQEAVARNNGTKIVVSRXXXXXXXXXXXXXXXGDESRVVTGGHNTSGNQNSIKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNIEKIEKDAVVMEKKDICFCCNESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTFPCSICNANLRSGPLLTLHEEQHKNRGKPYACKICGKDFTRSYHLKRHQKYSSCSANETDTMSCKVCDRVFYRLDNLRSHLKLHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKVHLRPYACDLCDEKFKTEKQLERHVKDHSRQKRASFTCSECKRNFRTADLLKEHMDAGDHTPKPQRAKRSSTKITGRTDCAICDKNFDSTDTLRKHIRTVHECDPDDIFGVDPPAAKQKKKDDKSTELVDAADEESSVGIDLNPATDSLEGNGVVVREFLLDEGDGTAQTIVLENETYTILPLEGEIEGGEEPAGRKPKAESKKKSSQVSPVVKKEQRKSLAASLAEAIADKVDEEDFTGEVLTEEDVKLKENVAKLIDMLVDPPILKKYGWPNTSEETVLCKVIENCGHDLTKGGDNYAEMEYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKSIKKSEAVVKVRI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00600464;
- 90% Identity
- iTF_00571314;
- 80% Identity
- -