Basic Information

Insect: Drosophila paulistorum
Gene Symbol: su(Hw)
Assembly: GCA_018152135.1
Location: JAECXG010000499.1:2547885-2553246[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00064 0.049 14.2 2.2 1 20 263 282 263 284 0.94

2 12 2.6e-06 0.00021 21.7 0.4 3 23 335 356 333 356 0.93

3 12 1.2 94 3.9 0.0 1 23 362 384 362 384 0.91

4 12 5.2e-07 4e-05 23.9 2.4 1 21 391 411 391 412 0.95

5 12 5.3e-06 0.00041 20.7 0.8 2 23 424 445 423 445 0.96

6 12 0.0001 0.0077 16.7 5.3 1 23 456 478 456 478 0.99

7 12 7.7e-05 0.006 17.1 0.9 1 23 484 506 484 506 0.97

8 12 9e-06 0.00069 20.0 0.7 1 23 512 534 512 534 0.98

9 12 1.9e-06 0.00015 22.1 2.2 1 23 540 562 540 562 0.97

10 12 2.2e-05 0.0017 18.8 0.5 1 23 566 588 566 588 0.96

11 12 2.4e-05 0.0018 18.7 0.3 1 21 596 616 596 620 0.93

12 12 7.3e-06 0.00057 20.3 0.4 3 23 640 661 638 661 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00064	0.049	14.2	2.2	1	20	263	282	263	284	0.94
2	12	2.6e-06	0.00021	21.7	0.4	3	23	335	356	333	356	0.93
3	12	1.2	94	3.9	0.0	1	23	362	384	362	384	0.91
4	12	5.2e-07	4e-05	23.9	2.4	1	21	391	411	391	412	0.95
5	12	5.3e-06	0.00041	20.7	0.8	2	23	424	445	423	445	0.96
6	12	0.0001	0.0077	16.7	5.3	1	23	456	478	456	478	0.99
7	12	7.7e-05	0.006	17.1	0.9	1	23	484	506	484	506	0.97
8	12	9e-06	0.00069	20.0	0.7	1	23	512	534	512	534	0.98
9	12	1.9e-06	0.00015	22.1	2.2	1	23	540	562	540	562	0.97
10	12	2.2e-05	0.0017	18.8	0.5	1	23	566	588	566	588	0.96
11	12	2.4e-05	0.0018	18.7	0.3	1	21	596	616	596	620	0.93
12	12	7.3e-06	0.00057	20.3	0.4	3	23	640	661	638	661	0.97

Sequence Information

Coding Sequence: ATGTCCAGGCAACAGAAATTCATAGATAACTCAATATTAAAAATTGGACGAGCAGTCAAGATGAATACCTCCAAGGAGGGTCAAAAATGGGAGAAAGAGACTGTATTGAAAATCGTGGATGTCGATGAACTTAGATCGCCGACCAAGGACAATAAACGCCCGTCTACACGTATGAAATTGCTGAACGATGTAACAGGATCGACCAAAACTTCGTCAAGTGGAAAGCCGGAAAAGCGTTCAGCAGCAGCAGGAGGAGGTGCAGTCATTAAAATACTCAACGATGATACGAACACACCCGTCAGAGCAGAGAAACGCACAAGCGGCGGCAGCAAAAAGACAGTAAGTCCCACTGTGCCGGCACCGGCGGCTGTGAAGATTCTTAACGATAAGCGATTCGCCTCACCAGTCATGGAAACGGTAAAGATTAAGGCCAATCCTAGCAAGAAAAAGAAAATGGATCACTATGTCCTCGAATCGGTTAAAAATGAAAACAGTAAAGCTCCGCCGGACGTCACAGCCAAAGTTGTCGTCCAGAACGATGATGAAGATGATGAGGACGATGATGGCGCCATTGCCTTTATTCTCGCCGACGTCGACGATGATGAGGAGGGTGATGACCAGGATGCGGTGGCACGTAATAATGGCACCAAAATTGTGGTATCCCGCGACGAAGACAAGGACGATGACGATGAGGATGACGATGACGAGGAAGGCGATGAGAGTCAAGTGGTCACTGGTGGCCATACTACATCGGCCAATCAGAATAGCATCAAAGAAATTGTGGAGCATGTCTGCGGCAAATGCTACAAGACGTTCCGTCGCGTCAAGAGTCTGAAAAAACATTTGGAATTCTGTCGCTATGACAGTGGCTATCATCTTCGCAAGGCGGATATGTTAAAGAACATTGAGAAGATCGAAAAGGATGCGGTGGTCATGGAGAAAAAGGATATCTGTTTCTGTTGCAATGAAAGCTACGACACCTTCCATCTGGGTCATATCAATTGCCCGGATTGCCCAAAGTCCTTTAAGACACAGACCAGCTATGAGCGGCACATATTCATCACTCACTCTGAGTTCAATACGTTTCCCTGTTCCATTTGCAATGCAAATTTACGCAGCGGACCCCTTCTGACGCTGCACGAGGAGCAGCATAAGAATCGCGGCAAGCCCTATGCTTGCAAGATCTGTGGCAAGGATTTCACAAGGTCCTATCATCTAAAGCGACATCAGAAATACTCATCATGCTCGGCCAACGAGACGGACACAATGAGCTGTAAGGTGTGCGATCGTGTATTCTATCGCCTAGATAATTTACGCTCCCATCTGAAGCTGCATCTGGGCACTCAGGTGGTTAAGAAGCCGGAATACATGTGTCATGTGTGCAAGAATTGCTTCTACAGTTTATCCACACTCAACATTCATATACGTACACATACGGGCGAGAAACCCTTCGATTGTGATTTGTGCGACAAGAAGTTCTCTGCTCTGGTGGCCCTTAAGAAGCATCGACGCTATCACACTGGCGAAAAGCCCTACAGCTGCACAGTGTGTAATCAATCCTTTGCCGTAAAGGAAGTCCTCAATCGTCATATGAAGCGGCACACGGGCGAACGTCCACACAAGTGCAACGAGTGCGGCAAAAGCTTCATTCAGGCCACACAATTGCGCACCCATTCCAAGGTTCATTTGCGTCCGTATGCCTGTGACTTGTGCGATGAGAAATTTAAAACCGAGAAGCAATTGGAACGGCACGTCAAGGATCACTCGCGCCAGAAACGAGCCTCGTTCACTTGCTCCGAATGTAAGCGAAACTTTCGTACTGCTGATTTGCTCAAGGAGCACATGGACGCTGGCGATCATACACCTAAGCCTCAACGCGCCAAGCGCAGTAGCACCAAAATCACTGGGCGCACCGATTGCGCCATTTGTGACAAGAACTTCGATAGCACCGATACCTTGCGTAAGCACATACGCACCGTACACGAATGTGATCCGGATGACATCTTTGGCGTAGATCCACCGGCTCCGAAGCAAAAGAAGAAAGACGACAAGTCCACTGAACTAGTGGATGCAGCTGACGAGGAATCGGCAGTGGGTATAGCCCTTAATCCTGCAACCGATTCGCTCGAAGGCAACGGTGTGGTGGTGCGGGAATTCCTCTTGGATGAGGGCGATGGTACCGCTCAAACAATTGTGCTCGAGAATGAGACCTACACCATACTGCCACTGGAAGGAGAAATCGATGGCGGAGAGGAACCAGCGGGAAGGAAACCCAAGGCAGAATCAAAGAAGAAATCATCTCAGGTTTCGCCTGTCGTTAAGAAGGAGCAACGTAAATCCTTGGCTGCCAGTCTGGCTGAGGCCATTGCTGATAAAGTGGATGAAGAGGACTTTACCGGCGAAGTGCTAACCGAAGAGGATGTCAAGCTGAAGGAGAATGTGGCCAAACTGATTGATATGCTAGTGGATCCACCGATATTAAAGAAATACGGCTGGCCCAACACCTCGGAGGAGACGGTGCTTTGCAAGGTCATCGAGAATTGTGGACACGACTTGACCAAGGGTGGCGATAACTACGCAGAAATGGAATATGGCTCACGTATGCGTGAATACTGCAAACTTCTCTTCACTGTGGTGATTCACAATGATTCCATAAAGTCCTTGCTCAACAATTTCCCCATTGACGACGTTATTGAATATGTGCTGGGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTAAGAAGTCAATCAAAAAGTCTGAGGCCGTCATGAAAGTTAAGATTTAA
Protein Sequence: MSRQQKFIDNSILKIGRAVKMNTSKEGQKWEKETVLKIVDVDELRSPTKDNKRPSTRMKLLNDVTGSTKTSSSGKPEKRSAAAGGGAVIKILNDDTNTPVRAEKRTSGGSKKTVSPTVPAPAAVKILNDKRFASPVMETVKIKANPSKKKKMDHYVLESVKNENSKAPPDVTAKVVVQNDDEDDEDDDGAIAFILADVDDDEEGDDQDAVARNNGTKIVVSRDEDKDDDDEDDDDEEGDESQVVTGGHTTSANQNSIKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNIEKIEKDAVVMEKKDICFCCNESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTFPCSICNANLRSGPLLTLHEEQHKNRGKPYACKICGKDFTRSYHLKRHQKYSSCSANETDTMSCKVCDRVFYRLDNLRSHLKLHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKVHLRPYACDLCDEKFKTEKQLERHVKDHSRQKRASFTCSECKRNFRTADLLKEHMDAGDHTPKPQRAKRSSTKITGRTDCAICDKNFDSTDTLRKHIRTVHECDPDDIFGVDPPAPKQKKKDDKSTELVDAADEESAVGIALNPATDSLEGNGVVVREFLLDEGDGTAQTIVLENETYTILPLEGEIDGGEEPAGRKPKAESKKKSSQVSPVVKKEQRKSLAASLAEAIADKVDEEDFTGEVLTEEDVKLKENVAKLIDMLVDPPILKKYGWPNTSEETVLCKVIENCGHDLTKGGDNYAEMEYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKSIKKSEAVMKVKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600464;
90% Identity: iTF_00612226; iTF_00618568; iTF_00523841; iTF_00503409;
80% Identity: -