Basic Information

Insect: Drosophila vulcana
Gene Symbol: hang
Assembly: GCA_008042555.1
Location: VNJP01011428.1:88898-98727[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.23 32 5.9 1.0 3 23 408 429 407 429 0.93

2 19 0.75 1e+02 4.3 3.1 3 22 537 556 535 556 0.89

3 19 0.0005 0.068 14.2 3.3 1 22 681 702 681 704 0.90

4 19 0.058 7.8 7.8 0.1 2 21 716 735 715 736 0.93

5 19 0.00058 0.079 14.0 0.2 2 23 866 888 865 888 0.95

6 19 0.0017 0.23 12.6 0.1 1 23 896 919 896 919 0.96

7 19 1.4e-05 0.0018 19.2 0.1 2 23 1008 1029 1007 1029 0.97

8 19 0.00024 0.033 15.3 2.9 2 23 1113 1135 1112 1135 0.97

9 19 0.019 2.6 9.3 0.2 2 23 1144 1166 1143 1166 0.95

10 19 0.00067 0.09 13.9 0.2 1 23 1179 1202 1179 1202 0.97

11 19 0.0001 0.014 16.4 1.1 1 23 1264 1286 1264 1286 0.99

12 19 0.0016 0.22 12.6 0.9 1 23 1294 1317 1294 1317 0.96

13 19 0.64 86 4.5 0.3 2 19 1325 1342 1325 1343 0.93

14 19 2.7e-05 0.0036 18.2 1.4 3 23 1430 1450 1429 1450 0.98

15 19 0.0042 0.57 11.3 0.1 1 23 1485 1507 1485 1507 0.97

16 19 0.0005 0.067 14.3 0.6 2 23 1597 1619 1596 1619 0.93

17 19 0.46 62 4.9 0.1 2 20 1639 1657 1638 1659 0.91

18 19 0.0055 0.75 11.0 0.4 3 23 1674 1694 1674 1694 0.98

19 19 8.5e-05 0.012 16.7 2.1 1 23 1888 1910 1888 1910 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.23	32	5.9	1.0	3	23	408	429	407	429	0.93
2	19	0.75	1e+02	4.3	3.1	3	22	537	556	535	556	0.89
3	19	0.0005	0.068	14.2	3.3	1	22	681	702	681	704	0.90
4	19	0.058	7.8	7.8	0.1	2	21	716	735	715	736	0.93
5	19	0.00058	0.079	14.0	0.2	2	23	866	888	865	888	0.95
6	19	0.0017	0.23	12.6	0.1	1	23	896	919	896	919	0.96
7	19	1.4e-05	0.0018	19.2	0.1	2	23	1008	1029	1007	1029	0.97
8	19	0.00024	0.033	15.3	2.9	2	23	1113	1135	1112	1135	0.97
9	19	0.019	2.6	9.3	0.2	2	23	1144	1166	1143	1166	0.95
10	19	0.00067	0.09	13.9	0.2	1	23	1179	1202	1179	1202	0.97
11	19	0.0001	0.014	16.4	1.1	1	23	1264	1286	1264	1286	0.99
12	19	0.0016	0.22	12.6	0.9	1	23	1294	1317	1294	1317	0.96
13	19	0.64	86	4.5	0.3	2	19	1325	1342	1325	1343	0.93
14	19	2.7e-05	0.0036	18.2	1.4	3	23	1430	1450	1429	1450	0.98
15	19	0.0042	0.57	11.3	0.1	1	23	1485	1507	1485	1507	0.97
16	19	0.0005	0.067	14.3	0.6	2	23	1597	1619	1596	1619	0.93
17	19	0.46	62	4.9	0.1	2	20	1639	1657	1638	1659	0.91
18	19	0.0055	0.75	11.0	0.4	3	23	1674	1694	1674	1694	0.98
19	19	8.5e-05	0.012	16.7	2.1	1	23	1888	1910	1888	1910	0.98

Sequence Information

Coding Sequence: atgggaatgggaatgggccTGGTCCAGGCTGGTGATTATTGCACCTGGTGGCCAGCAGAAATGATGATCACCTCACAGGATCGACTGTCGCTGCATATATGCCACGCCTGCATCAGTTACCTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGACAAAGCAGCGCCAGTGGCTGGACACCAGCAACAAGAGCAAGCTCTTCAACTACCTGGACCTGAACAGTGCCGAAAACGGTGGAACCTCCTCCGatcaccagcaccagcagcagcagcattcgCAGCCGCATCAACCGCAATCGGAGAATGAGCTCGACGCGGAGAAGGCGACGGCAGCGGCCACAACGGCCGCCAACATATTGGATGGCATATCCACGCTGAAGAAACGCAAATCTTTAACAGTCTATGTGAGTCCTAAACCGCAGCAGCTGCCACAGCATCAattgcagcagttgcagccaCCGTCCGGCAGATTGACGGCCACGGCGACGTCCGGCACCAACGCGCAGCAAACGTTGCAGACCCTTCTCCTGCAGCCCAAACTGTACTTGCCACTGGATATAGCGGTGCCACCACTGCCACCGCTGCCATCAGTGGCTCCTGGACCgattgctgcttctgcttctgctcctgcgcCGCCTGCCCCTGCTGCCGTTCCTGCTGCTGAACAGCCGCTGCTTTCGGGATTCTCCGGTCTAACCGGAATTGCTggtgtgggtggtggtggaaTGGAGAGTTTGTCGTTGTCGCTGCCACTTGATTTCAGCCAAAGTTGCAGCAGCGGTCACGTCCAACAGTCGGGTTTGCTGCCTCTGGCCCCGGCCACAGCCACAGTCACGGCTACGGCAACGTCCACGTCCAATCCTCCGGGCATCGCGTCAGCCACTGCCacttctggctctggctcggCAACTGCATCAGCATCCGTGTCCACGGCTCCGTTGCTCATGCCGCCGCTGCCAGCGTTGCCCATCAAAGATGAGCCCATTGACACGGACGATGACTACCAGATGAAGATGATAGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAGCGTTCCGAGCACGAGGGTGATATGCCATTGATGGCCTCGGACTACGACTATACGGCCCAGCATGGCGTTAATGCCCATTCTTTGGCCGCCGGACTGCCACCGAATGCGGTGGCCAATGTGGCCGCCGCCGGGGATTCCAAGGTGGCCAGCTGCCGGGCCTGTAGCCTGCAGTTCTCCACCCGAGCCAATGCCCGACGGCATGAACGCAATCTGCACCCGAACCTCTTCCAGCTCTCCACGGACTCGCTGCACAATACGACAGTGACGAAGCCAACGCCAGCTCTGGCCGCCGCATTGGAAATCCAacgggcggcagcagcagcggccaccGCAGAGGCGAATCGTGCTGTGGGCGCTGCCGGCGGTAATATCACTCCCCAGAAATACCGTCAGGTGGTGATGAATGCGTTCATCAAGTGCGAGGGCGGCGGCTATGACTATGACAATCCGGAGCAGTATCGTCCACTGCTCAGCCACGACAAGGTGGAGTTCATCGAACAGAACGAGGAGTTCCTTGAGCAATACCAGACGATgacctgccgctgctgcagcaagTACTTTAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGCTGCTGCCGCGCAATTTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCATCTCAAGAAGCGCAACTGCATAAATCTCTACAGGGTTTTGAATACGCTGCGCGGCAAGACACCAGTACTTCCCATCTCTGCCACGGACGCGGACgcggatgtggatgcggatgcaGCAGCCGCTTCGGGTGCTGACGATGGAGCCACCGCTGTAGCGGTGGCAGATGCCGGCGCTGGCGTTGTCACAATGGCCAGTCCCACGGTGACCATTAGCGGCGAGACCACCGGCACCACTCCCAGCGGCGGTGAACGCCCGGAGAAGCTGCGCGCCAAGGAACTGCTGGTGAACAAGCTATACGAATGCAAGCTCTGCCCCAAGGGTTTCCGCACCAAGCACGAGTTTCGTACCCATGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAACTCTATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGACAGGCGACGGCACTACAACAACATGGACTGCATTGTGCGACTGCGTTGCATGACGTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGATCACGTCTATCAGGATCATTTGGGCGGGGTGGGCGGTGGCGGTGCCAGCAGTGATAATGCCTCCACAACAGGCAGCGGCCTGGCCAGAAGCAACAGCATGGAGCATTCGCCGGGCAAGAGGAGTTTGCTCGGTGCCCTGGGCATTGGCGTTGGTTCATCGGCGGAAGAGTCGCGCAGCAGCAGTGTGGCACCCACACTGACATCCACGCCCAAGCCAGCGGGTGGCACAACCACAACAACTGCCTCCGCGCCCAGTTCGGCGAATCGTGGTGATGCGGCCGCACCCAAATCCCAATACTTTTCGCGAATGCCGCAGGTGTGTCCCATTTGCGGACAGCAGTACAATAACTACAACAACGTGCTGCGCCACATGGAATCGAAGCATCCCAACAAGCTGCCCGAGACATACAAGTGCGTGCGTTGCGGCCTGGGCTATCCAAGGATATCGTATCTGCGGGAGCACATGATCAATGTGCATGGCGTGGACAAGAACCGGCACTCTGGTGGCTTCGAGTACATCGTGAACGCTGATGCCGTGAAGCTGGCGGATGGCAGCACGCCGAATGTGTACACGGGTCGCTACGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACCCTCGACGAagacgaggaggaggcagcagcaggcagcgtGGCCAAAAAGATCCGTTTGGatgacagcagcaacaacagcagcttGACCGGCGTCGCCAGCAgtcagcagcagaaggaatGCCCCATTTGCAATGCCGTGTTTAGCAATAACATTGGCCTCTCCAATCACATGCGCTCCCATTACACAGCTGCCAGTGTGGTGACCGCTGCTCTGGCGGCCGCCAATCGCATGACACCCAAATCACTGACCATCACAGCAACTCCAGCAACGGCAGCGGACGCAAGTCCAGAGGCATCTAACGCGGCAAtggccgccagcagcagcagcagcaatgttGTGCCGCCGGCAATGGCCAATCAAACGCCCCAGGAGCAGGCCGTATTCCGACGAAGTTTGGATCAGGCGGCCGACCGTCGCTTCCGGCGAATGCGTTGCCGGATTTGCCAGCGGCGCTTCAGTTCGAAGAAGTCCTATCGCTACCACATGCTGACGGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCCGAGTTCGCCTACGAGAAGGGTCTGAAGGTGCATCTGTTCAAGGTGCACGGTCGGGCGATCAAGGACGAGATGATCATCAAGCAATTCGAGTGCGAAGTCTGCTCGATTGTATACAGCTCGGAgatggagctgcagcagcacaagCGGAGTGTTCACAAGCTAACCTCTGcctcggcatcggcatcggcctctgcttctgcctcagcatcggcatcggcatccaCTTCCTCGAAGATGGAGGACGACGTTCTGATGGATGAAGAAGGCAAGCCAGCAGCCGATCTGTCCACCCTTTCCGCCAACGCATCGGGACTGGGAGTGGGTACGCCGCTGTACTGGTATCAGTGCAAGTACTGCCCCTCGAACTTCAACACCAACAAGAAGCTGGCCATTCACATCAACTCGCACGACGAGTTTGATTCGAATGATTATTCCTGCAAGGATTGTGGCAACGTCTATAGCGGACGCAAGAGTCTATGGGTGCATCGCTACAAGAAGCATCCACAGGTGCCAGACCCGGCCGAGTGCTCGCTGTGCCGCAAGATCTTCTTCGATCGCCAGATGCTGGACAATCACACGCCCACCTGCAACCGCAAGCCAATCACCTCGACGGGtgcccaccagcagcaggattcgctgcagcagcagcaggcggcacTGCAACGTGCTGTTTTCCGGCACAAGACGGGtgacgatgacgaggaggaggatgatgggcagcagcagctggaggagggcGGCGATAGCAATGGGGGCGCAACAGCGTCGGGAAGCGCCGCTGTGGCAGCGCCTCCTGCTGCCCCGCCTGCACTGAAGATCCGCATACCGGAGGTGGCCTGCACCATTTGCGGCGCACGGTTTACCGATCAGGAGCACTTCAGCAAGCACATCCAGAAGCACGAACAGGAGCTGTATGTGGACAATCCGCTGGCGGCGATGTTTGACGATGGGCCGGCGGATGCCGGTCAGTTCCAGGTTGAGCGGCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCGCAAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCACActaccagcaacaacaacaacaacagcaacagctcgATGCTGCACCTCCGCGAGCTGCATGCAGTGGGGCTGATGcccaaccagcagcagcagcagcaacagcagagccacaacagccactcgagcagcagcaacaacatcaacatgaaccacagcggcggcagcagcagcagcaaatcgATGAAGCGGAAGCGTGAACTCAAATGCGAATACTGCGCCTCCACCttcatcagcaacaacaatctgCGCCGCCACATGTACGAGCTGCACAAGCACGAGGTAAGCAATCTCCCAGAGCCGCCGGTCATCTTGGTGGACGATCATCTCCAGTGTAGACGCTGTCAGCTCAGTTTCGAGACGAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCGAAGGTGGTGCGTCCATTCTGTCCCTTCCAGTGGGGCTGCGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTAATGAACCACATCAACAACCATCTTAAGGAGGAGGCGATGGCAGGAGGAGCACAAAAAGGGGATGAAAGCGATGACCTGGACGAGGAGGATAGCTCCGGCGAGGAGGAAGAAAGTTCAGGCACGGGAGACGATGAGGACGATGACTCcgatgatgacgaggaggaagatgaCGAGGGCGATGGAGGCGAAGtggcagtggcagtggcactgTCGCCATCGCAACCGCTGATGAATGGCAATGGCAAGGCCAAGTCGAAAATGCCGCCACTGATTATGCACAGTtccgacgatgaggaggaggatgatggCGTTATGCCCATCGATGACATTATCGAAGAGGAATTcgacgaggaggatgatgCCATGCCAGATGCCGATATCCAGGATGTGGATGATGCCATCGAGGAGGTGGATGACGATGATTTGGATGAGGGGGATGACGTGGAGatgatggaggaggaggaggaggaggtggtatCGGCAGCCTCCTCATCGGAGAGCGAGTCCACGTCAACGACCACGTCCAATTCGCACTCGCATTCACATTCCACGGGTGAGCGGCGTAAGAAGAGGGCTGACGATCAGTTGAATGATCCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTTGATTCCCAGGAGCTACTCCAGAGCCACATCAAAAGCCATTTTCTCAATGGGCCAAAGCtcacagccgcagcagcagtagccacaacagcagcagccggcagCAGCGCGGCGGCCTCGTCAAGATCGGCAACGGCGCCGGCAACAGCAAAGACGAAGCCTGACTCCAAGTCAGCGCTGCTggccaacaataacaacaataagagCAGCAAGactgttgcagcagcagctgcagctgccacaAACTGA
Protein Sequence: MGMGMGLVQAGDYCTWWPAEMMITSQDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDTSNKSKLFNYLDLNSAENGGTSSDHQHQQQQHSQPHQPQSENELDAEKATAAATTAANILDGISTLKKRKSLTVYVSPKPQQLPQHQLQQLQPPSGRLTATATSGTNAQQTLQTLLLQPKLYLPLDIAVPPLPPLPSVAPGPIAASASAPAPPAPAAVPAAEQPLLSGFSGLTGIAGVGGGGMESLSLSLPLDFSQSCSSGHVQQSGLLPLAPATATVTATATSTSNPPGIASATATSGSGSATASASVSTAPLLMPPLPALPIKDEPIDTDDDYQMKMIDESDDMVDPTMFLERSEHEGDMPLMASDYDYTAQHGVNAHSLAAGLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSLHNTTVTKPTPALAAALEIQRAAAAAATAEANRAVGAAGGNITPQKYRQVVMNAFIKCEGGGYDYDNPEQYRPLLSHDKVEFIEQNEEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNTLRGKTPVLPISATDADADVDADAAAASGADDGATAVAVADAGAGVVTMASPTVTISGETTGTTPSGGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGGASSDNASTTGSGLARSNSMEHSPGKRSLLGALGIGVGSSAEESRSSSVAPTLTSTPKPAGGTTTTTASAPSSANRGDAAAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDEDEEEAAAGSVAKKIRLDDSSNNSSLTGVASSQQQKECPICNAVFSNNIGLSNHMRSHYTAASVVTAALAAANRMTPKSLTITATPATAADASPEASNAAMAASSSSSNVVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSEMELQQHKRSVHKLTSASASASASASASASASASTSSKMEDDVLMDEEGKPAADLSTLSANASGLGVGTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAHQQQDSLQQQQAALQRAVFRHKTGDDDEEEDDGQQQLEEGGDSNGGATASGSAAVAAPPAAPPALKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTSNNNNNSNSSMLHLRELHAVGLMPNQQQQQQQQSHNSHSSSSNNINMNHSGGSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVILVDDHLQCRRCQLSFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEAMAGGAQKGDESDDLDEEDSSGEEEESSGTGDDEDDDSDDDEEEDDEGDGGEVAVAVALSPSQPLMNGNGKAKSKMPPLIMHSSDDEEEDDGVMPIDDIIEEEFDEEDDAMPDADIQDVDDAIEEVDDDDLDEGDDVEMMEEEEEEVVSAASSSESESTSTTTSNSHSHSHSTGERRKKRADDQLNDPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKLTAAAAVATTAAAGSSAAASSRSATAPATAKTKPDSKSALLANNNNNKSSKTVAAAAAAATN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00478146;
90% Identity: -
80% Identity: -