Basic Information

Insect: Drosophila virilis
Gene Symbol: -
Assembly: GCA_007989325.2
Location: CM017605.2:29429055-29432868[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.1 5.4e+02 1.1 1.9 3 16 57 70 56 72 0.84

2 14 3.9 2.3e+02 2.2 1.1 1 23 165 191 165 191 0.76

3 14 0.00021 0.013 15.6 0.7 1 23 197 220 197 220 0.97

4 14 0.00035 0.021 15.0 4.6 1 23 225 248 225 248 0.96

5 14 0.00037 0.022 14.9 4.5 1 23 253 275 253 275 0.98

6 14 4.7 2.8e+02 2.0 5.7 2 23 282 305 281 305 0.90

7 14 0.00041 0.025 14.7 1.0 3 23 315 336 314 336 0.95

8 14 0.022 1.3 9.3 0.3 1 23 342 365 342 365 0.95

9 14 0.094 5.6 7.3 0.2 5 23 381 400 376 400 0.89

10 14 2.6e-05 0.0015 18.5 0.4 1 23 429 451 429 451 0.98

11 14 2.4e-06 0.00014 21.8 4.2 1 23 457 479 457 479 0.97

12 14 7.7e-06 0.00045 20.2 0.1 2 23 486 507 486 507 0.97

13 14 0.001 0.062 13.5 0.9 1 23 514 536 514 536 0.99

14 14 0.00067 0.04 14.1 5.0 1 23 542 565 542 565 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.1	5.4e+02	1.1	1.9	3	16	57	70	56	72	0.84
2	14	3.9	2.3e+02	2.2	1.1	1	23	165	191	165	191	0.76
3	14	0.00021	0.013	15.6	0.7	1	23	197	220	197	220	0.97
4	14	0.00035	0.021	15.0	4.6	1	23	225	248	225	248	0.96
5	14	0.00037	0.022	14.9	4.5	1	23	253	275	253	275	0.98
6	14	4.7	2.8e+02	2.0	5.7	2	23	282	305	281	305	0.90
7	14	0.00041	0.025	14.7	1.0	3	23	315	336	314	336	0.95
8	14	0.022	1.3	9.3	0.3	1	23	342	365	342	365	0.95
9	14	0.094	5.6	7.3	0.2	5	23	381	400	376	400	0.89
10	14	2.6e-05	0.0015	18.5	0.4	1	23	429	451	429	451	0.98
11	14	2.4e-06	0.00014	21.8	4.2	1	23	457	479	457	479	0.97
12	14	7.7e-06	0.00045	20.2	0.1	2	23	486	507	486	507	0.97
13	14	0.001	0.062	13.5	0.9	1	23	514	536	514	536	0.99
14	14	0.00067	0.04	14.1	5.0	1	23	542	565	542	565	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCAAGGTGCGATTTCgaaaatggcaacaactaTTGGCTGGACATGTTCCATCCAACGCGTTGGCAGAGCGAGATGGCGCAAATACGCTTGGAGTTTGTCAACTGGAAGTTACAGATATCACCAAACGATGGACTGCCACAAAAAATTTGCAGCGATTGCTTTACAAAATTCTGCTCCATATACACATTTCGCATGGCCTGCCAGGACGCACAGTTAAAGTTGTcgaatatttttgataaaatcGATGCGAATTCGCTCTATGATAAAAACGACGAGGACAATATTGAGGTGGATGTGGATGAAATAGTAACagaaacaacgacaacaacacaaaacacTGCCAATATTGAGGCCAACACGCAAACACCCATAGAAATCTTTGTGGAAACGATTAGCATCAACGAATCTGAATCCTTACAGCCAGATGAGGAAACCGATTTAGCTTCTGATTACAACACATTAAACATAAGCTATGCTTGTAAATTTTGTCACAAGCCACAGGAAAGCTATGAGCTGCAGCACCTATTACTCGAGCACATCAGTAACGCACACGATCCGGATCAGCCATACAACTGTCCGGAGTGCACAGAGTGCTTCCAAGATGCCGCCTCACGTACGGTGCATATGAAGAGCGTTCATGTCGTTAAGCATCACACCTGTGAGGTGTGCGGCAAAAAGTACGGAGATCGTCATAATCTCGACCATCATATTGAGAAATATCACTCGGAAACGGATTTCGAGTGCAGCCTGTGCGAGAAACGTTTCTTTACGCGCAAAAGCCTGCACTACCACATGAACTGGCACAATCCGGAGCGCCAGCTCAGATGTCGCCACAGCGGCTGCGACAGGCTGTTTATCAACCAACGACATCTCAAGTGTCACGAGGCAACGCACTCAACGGGCCCCCGCAAGAGCGAATACTGCGGCTTCTGTGGTAAAGCTTTCATACACGTTAAAACTCTACGTTGGCACATCTATCGACAGCATGGCGGAGAGAAGCCTTTTAAATGCGCCAACTGCACTGAGGTTTTTGGCTCCTATGCGGAAAAGCGCTTACACATGCTGGAGCAGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAATGCATGTTTCAGTCCTGTCGCCAGGAGTTCGACACCGAACGGGAGCTCATCCAGCACATGAGCGTTGAGCATGTGCAGCGCGAACCCTCCACTCCGATAATTGCGAATAATAAACGCGTGCTCCAGTGCAAACGGGAGCGACAGTATACGGGCCTCTTCCAGTGCGGCAGCTGTACGCAACGTTTCAACATGAAGTCCGCCCTGGAGCGGCACATGGCTGTCCATTCCGCTGACCGGCTGCATGCCTGTCCGCACTGCTCCAAGCGGTACAAGCGTGCCCAGGACCTGAAGTGGCACATGAAGACGCACGCCAATGAGAAGCCCAATGTGTGCGATGTGTGCGGCAAGGCGTTTGCCCTGAAATATGTGCTCACCCAGCATATGCGCAGTCATGAGGTTCTTGAGAAGAACTTCAAGTGCGAGACCTGCGGACGGGCCTATCTCTTTGAGAAGTCTCTGCGTCTGCATCAACGCGTTCACACGGGCAACACCTACTACAAGTGCGATCTGTGCCAGGAGCGTTTTGTCACTCACATcaaatttaaaaCTCATATGAAAAAGACACATGATAGCAGCCAGTCGAATGCCAAAGATACGCTGGATGATTTGATCAACATTGTGATTTCCTGA
Protein Sequence: METCRTCARCDFENGNNYWLDMFHPTRWQSEMAQIRLEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDANSLYDKNDEDNIEVDVDEIVTETTTTTQNTANIEANTQTPIEIFVETISINESESLQPDEETDLASDYNTLNISYACKFCHKPQESYELQHLLLEHISNAHDPDQPYNCPECTECFQDAASRTVHMKSVHVVKHHTCEVCGKKYGDRHNLDHHIEKYHSETDFECSLCEKRFFTRKSLHYHMNWHNPERQLRCRHSGCDRLFINQRHLKCHEATHSTGPRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCANCTEVFGSYAEKRLHMLEQHTENLTHQERSECMFQSCRQEFDTERELIQHMSVEHVQREPSTPIIANNKRVLQCKRERQYTGLFQCGSCTQRFNMKSALERHMAVHSADRLHACPHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKTHDSSQSNAKDTLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00531129;
80% Identity: -