Dvil007357.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila villosipedis
Gene Symbol
RREB1
Assembly
GCA_035043025.1
Location
JAWNNF010000024.1:5518846-5525788[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.036 2.3 8.7 0.8 1 21 265 285 265 287 0.93
2 13 0.00034 0.021 15.1 0.2 1 23 297 319 297 319 0.98
3 13 0.00025 0.016 15.5 7.2 1 23 325 347 325 347 0.98
4 13 0.24 15 6.2 1.7 2 20 576 594 576 596 0.93
5 13 0.016 1 9.8 0.2 1 23 744 766 744 766 0.97
6 13 1.2e-05 0.00079 19.6 0.7 1 23 776 798 776 798 0.99
7 13 0.00083 0.053 13.9 2.0 1 23 804 827 804 827 0.97
8 13 0.003 0.19 12.1 2.0 1 23 1105 1128 1105 1128 0.95
9 13 8.7e-05 0.0055 17.0 0.3 2 23 1524 1545 1523 1545 0.97
10 13 0.15 9.3 6.8 6.3 1 23 1551 1574 1551 1574 0.97
11 13 9.4 6e+02 1.1 3.4 1 23 1692 1715 1692 1715 0.78
12 13 0.0085 0.54 10.7 0.5 3 23 1778 1798 1776 1798 0.96
13 13 0.0013 0.086 13.2 4.8 1 23 1804 1826 1804 1826 0.99

Sequence Information

Coding Sequence
ATGCTcgccacacagcagcagcagcagcagcaacaacaacaacagcaacaagcaactgcagcatcagcagcaacacatgAGGATGCTCGGGATTTGGGGTTAATGGAGACGCGACAACGTCGCGATTCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCCAAaaagttgagcagcagcagtggcgcACCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGCAAACTGCGacagcaacaccaccagcagcagcaacagttgccactcTCCGatgaggagcaacagcagcagcagcagcaacagctgttggaCTCATCAGCTCAGCGACCGCGTCACAAGCAGCGACGCAGCgccgttgctgccgctgccagcgCCAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCTGAATCGGGCTTCGTCGATGGCAGCGCCCTCAGTGGCTATCtgcttggcagcagcaacaacaacaacaacaacaataataataataacagcaacaacaacaacaacaatatcagtaatagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcagcgtcggcaGCGCAGCATGCGCCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCCGGTGATGAGCACATGAAATATCTGTGCCCCATTTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAggcgtcgcagcagcagcagcagcaacagcagcagcactcgcaacagcagcagtcgacacaacagcagcaacaggcacagtcgcagcaacaacagcagcgacgccagcagcatgcaggtggagctggagcagctggtTCGGTATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcagtccaaccacaacaacaacaacaataacaatagccacaaaacgaacaacaacaataacaacaacaacaacaatgaggaTGAGCTTGAGCTGGAGGATGAGCAGCTAGTGCTGAGCAGCAAACAGCGACGCCACAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGCCGGATGATGATTCGGATGTGGACAGCGCTGATAGCGTTGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATCGCATTcaccgccgctgctgctgcagagcTGCCCGGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAATGTGAGGTGATCTTTGCCACACATCGGCAGCTGCAGGCGCACAGCTGTCGAGGACTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAGCTGGaggagcagcaccagcagcagcagcagcacgaggAGGAccacgaacagcagcagcacaagcaggaggaacaggagcaggctGAACAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTGCTTCCCTCACCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAACATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGACGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGCATGAAACTGCGTGGTGAGTTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCCGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTGCGGCACATGCGCACCCACAACGGTGATCGGCCCTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGACATGGCAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCGCGGACCGAGCCCGATATCCTGACGGAGTTCAGCGGCTATCGTTGTGCAACACCCACGGAGCACAGCTCATCGGCTAGCTCCTCGTCACAGCTGAAGCACATGTTGCTGGCGGAGCCGACGCCGGCCGTAAAGgtagctgcaacaacagctgcagcagcagcagcaacaacaacatcgctGCCACAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCGGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCCCAGCTACTGGCCGAGCAACGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcagcaacagcagcagcaacaacaacagcagcaacagcagcagcagcaacaattgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAACTTCATGCTTCAGCAATCACCCGGTTTTCCTTTCTTTGGTTTTATggcgccaccgccaccaacaacggcagcggcagcggcagcagcagcagcagcaacagcagcagcagacaagtcaatgacaacaaatccaacagcagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCAGTGCCACTGGCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGCCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGGCAcgtgaagcagcagcatccacagtTCTATGCGCAGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTCCATCCTCGAGTGCTGCCCAAGCGGCAGCCGCTGctcacgcagcagcagccgccgccgctgcagcaATGAGTAAtctcagccagcagcaacagttgcagcagcagcagcaacagttgcagcattcgcattcacatcaCGTCCATGCGCCAATCTCGGAGCAGgtgaaatatgcaattttgGCGCAGCAATTGAAGGCGCGCAAGGATACCGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGTTGCATTttagctacaacaacaacaataacaacggcaacggcaacagcatcagcagcagcaagcagcagcaacaacagttgtgCAACAACACTGGCAACTCTTTGGTGCTGGACGACGATGAGCCGCCCAAGCTGATCATTGACGAGGATGACGAGGATGTGGATGGCgaggacgatgaggatgaggaggaggagcaggaatttgatgttgatgaggaggagcaggaggatgAGGAGATGGACTTGGACGatgagcatcagcagcagccgcacgaggacgatgacgatgatgatattgatgatgatgatgcagcagcatcagcagctgctgcagcagaggagtcgcagcaacaattgcagccaaCCAAGGACAAGCTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCTGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCAGCCGCCGAGAAGCAGCCGCATCCTCAATCGGAGTCCATCGGCGGCAATAAGCCGGCAACGCCAACCACAATGAAAACGATGATTGCACAAGCGGAATCGGTTGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTCGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCATATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaatGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAACCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGTTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAAttggaacgggaacgggaacgggaacacCAACAGTTGATACAACAGTTGCGCCAACAAATGGCCgccgctgcagcggctgctgtcgctgtggCCGCCGTTGCTGCACCAGCGCATCCACCACCGCCAGACCAATCGCCACCAGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAGTTCTCATTCGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTGCACGCACACGAGTTCGccctgctgctggccaagggAGCCATCGAAACGGATGCCCAgctgcagcaccaacagcagcagcagcagcaacagttgccagcgACTGGCGGCGCTCCGCATTCGGATGatgaggctgctgctgtcggcaCCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGCCACATGCGCACCCATTCCGGTGAGCGGCCCTTCCAGTGCGAGATCTGCCTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGATCATCAATCCGATTGCTCCGAAGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaataacaacaacaacaacacttgccagaacaacaacaataataacaacaataacaacaacaatagcaatagcaagcAGGTGCTGCGCGAGCTGCTGGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagccgcagcagcagcagcagcagctgctgtggccAGTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence
MLATQQQQQQQQQQQQQATAASAATHEDARDLGLMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHHQQQQQLPLSDEEQQQQQQQQLLDSSAQRPRHKQRRSAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGSSNNNNNNNNNNNSNNNNNNISNSSSSSAVAQSAAAAAASAAQHAPSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQHSQQQQSTQQQQQAQSQQQQQRRQQHAGGAGAAGSVSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNNSHKTNNNNNNNNNNEDELELEDEQLVLSSKQRRHKAALNNNNIIRDEEHENRPDDDSDVDSADSVAQVITSTPDVATLLASGGTSPTHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESELEEQHQQQQQHEEDHEQQQHKQEEQEQAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTEPDILTEFSGYRCATPTEHSSSASSSSQLKHMLLAEPTPAVKVAATTAAAAAATTTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQQQQQQQQQQQQQQQQQLFGAGDAAAQYMQQLLRNFMLQQSPGFPFFGFMAPPPPTTAAAAAAAAAATAAADKSMTTNPTAAAAGATAATIAAMPLSLPVPLAAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRHRSGHHVMRERAPSSSAAQAAAAAHAAAAAAAAAMSNLSQQQQLQQQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNNNNGNGNSISSSKQQQQQLCNNTGNSLVLDDDEPPKLIIDEDDEDVDGEDDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQPHEDDDDDDIDDDDAAASAAAAAEESQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKAAAEKQPHPQSESIGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIQQLRQQMAAAAAAAVAVAAVAAPAHPPPPDQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQQQQLPATGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSEDEQLLPCSPPSTPTPTNNNNNNNNNTCQNNNNNNNNNNNNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
-