Basic Information

Insect: Drosophila villosipedis
Gene Symbol: hang
Assembly: GCA_035043025.1
Location: JAWNNF010000024.1:11018911-11031277[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.34 21 5.7 1.0 3 23 480 501 479 501 0.93

2 17 0.43 27 5.3 3.2 3 22 608 627 606 627 0.89

3 17 0.00072 0.046 14.1 3.3 1 22 738 759 738 761 0.90

4 17 0.083 5.3 7.6 0.1 2 21 773 792 772 793 0.93

5 17 0.00084 0.054 13.9 0.2 2 23 934 956 933 956 0.95

6 17 0.0024 0.15 12.4 0.1 1 23 964 987 964 987 0.96

7 17 0.00018 0.012 15.9 0.2 2 23 1075 1096 1074 1096 0.97

8 17 0.00035 0.022 15.1 2.9 2 23 1196 1218 1195 1218 0.97

9 17 0.027 1.7 9.1 0.2 2 23 1227 1249 1226 1249 0.95

10 17 0.0016 0.1 13.0 0.3 1 23 1262 1285 1262 1285 0.97

11 17 0.00015 0.0096 16.2 1.1 1 23 1343 1365 1343 1365 0.99

12 17 0.0023 0.15 12.5 0.9 1 23 1373 1396 1373 1396 0.96

13 17 0.082 5.2 7.6 0.4 2 19 1404 1421 1404 1422 0.94

14 17 0.0019 0.12 12.8 0.3 3 23 1529 1549 1528 1549 0.98

15 17 0.0013 0.081 13.3 0.1 1 23 1584 1606 1584 1606 0.97

16 17 0.00071 0.046 14.1 0.6 2 23 1692 1714 1691 1714 0.93

17 17 0.0077 0.49 10.8 0.3 3 23 1770 1790 1770 1790 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.34	21	5.7	1.0	3	23	480	501	479	501	0.93
2	17	0.43	27	5.3	3.2	3	22	608	627	606	627	0.89
3	17	0.00072	0.046	14.1	3.3	1	22	738	759	738	761	0.90
4	17	0.083	5.3	7.6	0.1	2	21	773	792	772	793	0.93
5	17	0.00084	0.054	13.9	0.2	2	23	934	956	933	956	0.95
6	17	0.0024	0.15	12.4	0.1	1	23	964	987	964	987	0.96
7	17	0.00018	0.012	15.9	0.2	2	23	1075	1096	1074	1096	0.97
8	17	0.00035	0.022	15.1	2.9	2	23	1196	1218	1195	1218	0.97
9	17	0.027	1.7	9.1	0.2	2	23	1227	1249	1226	1249	0.95
10	17	0.0016	0.1	13.0	0.3	1	23	1262	1285	1262	1285	0.97
11	17	0.00015	0.0096	16.2	1.1	1	23	1343	1365	1343	1365	0.99
12	17	0.0023	0.15	12.5	0.9	1	23	1373	1396	1373	1396	0.96
13	17	0.082	5.2	7.6	0.4	2	19	1404	1421	1404	1422	0.94
14	17	0.0019	0.12	12.8	0.3	3	23	1529	1549	1528	1549	0.98
15	17	0.0013	0.081	13.3	0.1	1	23	1584	1606	1584	1606	0.97
16	17	0.00071	0.046	14.1	0.6	2	23	1692	1714	1691	1714	0.93
17	17	0.0077	0.49	10.8	0.3	3	23	1770	1790	1770	1790	0.98

Sequence Information

Coding Sequence: ATGGACAACTCTGGGCGAAGTCCATCCCATGACCATCCCACCATAAAATGGTATACCGATGGATCACTCACGAATCAGGGCACTGGCCTTGGAGTGGTGGGTCCTCGGGTATTCTACCATGAATCCCTGGGAACGCATaccagcatatttcaggctgagATCACATCGGTGGATCGTCTGTCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCATGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCATTGGCTGGAGACGGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAGCACTattgagcaacagcaacaacagcagcagcagcagcagcacgattTAAAAATGGATTCAGCGACGTCTGCAGCGGAAAAGGCGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCGAGTcccaagcaacagcagcaagcacagcaacaacagtcgcagcaACATTCTCAGCAACAGCATGCAACAGGGGCAAGATCAACAACGAAAACATCAGCTGCGGCGGCGTCGGTGGCAGAGTCGCAACAAACATTGCAAACCCTTTTATTGCAGGCgcccacagcagcagcggcagcagcgacattGGCAACGTCgtcaacacagcaacagcaacagcagcgcaagtatcaacagcagctgcagcagcaacgtggcaagcagcagcaacatcagtatcatcaacagcagcagcggcagagTCGCGTTCGTCAACCgcgacgacagcaacaagcgGCAACGAGCAAATTCAGGAGCAAGTTGTATGTGCCATTGGATATATCGGTGCCAGCACTGCCAGAGCTgttgccgccaccgccgccagctgttgctgatgcagcgtcgttgccattgccgctgtcgctgccacTTGATTTCAGCCAGAATCCGAATCCAAATCCCAATCcaaaacaaaatctaaatCAGAGATATACAAGTAGCGTTTTAGTGCCGCAGCCGCAGACGCCGCCGATGCCGCTGCCCCCGCCAGTTGCAACAATGAGCAGCAACGAGGCTGCCATTGGtggtgcaactgcaactgcaaccgcaGTCACGACTCCATTGCTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCCAGGACGATACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTAAATACCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCGGCTGCATCGCTGCCGGCCAGCGCCGTTGCAAATGTGGCCGCCGCTGGCGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGACTCACCAAATAATACGCCAATCACCAAACCGACACCGGCCCTTGCCGCCGCCTTGGAAATACAGCgtgcagcggcggcggcagcggcaaccgCTGAGGCTACGCGTGCCGCTGCCGGTGGCAATATATCGGCGCAAAAGTATCGACAGGTGGTGATGAACACGTTCAGCAAATGCGAAAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAGCTGTTGTCGCACGACAAGATCGACTTCATACAGGAGAACAGCGAGTTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTACTTCAGCACGTACAAGAACTTTATGGCGCACGTACGCAAAAAGTATCCGTTGCTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCACCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTTTATGCCAAtgtcaatgccaatgccaatgccccATCCACTTCCACTGCAGCCGCAACGACTGCTgtacaccagcagcagcagttgatgaCAGCAAACgaaacagcagcgacaacaacatcaacaacatcaacggATCGTCCGGAAAAGTTGCGTGCCAAGGAGCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTTCGCACAAAGCACGAATTTCGCACCCATGTCTACGACAAGCATGCAGATGTTCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCCGTTGATCGTCGAAGACACTACAATAACATGGATTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCGAAACTGGAGACGCATCAGCGTTTCCTCGACCATGTCTATCAGGATCATTTGGGTGGGGTGAGCAGTGATAATGCATCGTCCACGGCGACGACCAGCGGCTTGGATCATTCGTCCGGCAAGCGCAGTTTGCTGGGCGCCCTTGGCATCGGCATTGTCAGTCAATCATCCAATGATGAGtcgcgcagcagcaacagcaacaaccacaacaataacaataataacaacagtaacaacaacaacaataatgcacCTTTAACTTCGACTCCTAAACTACCAATCGtcacaggagcagcaacagctggtggaggaggaggagcagcagcaaccagtgGCAGTCGAGATGCACCCAAATCACAGTATTTCTCACGAATGCCACAGGTCTGTCCGATCTGTGGCCAGCAgtacaacaactataacaatgTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCAGAGACATATAAGTGTGTCCGCTGCGGATTGGGCTATCCCCGGATCTCCTATCTGCGGGAGCACATGATCAATGTGCATGGCGTTGACAAGAATCGGCATTCGGGCGGCTTTGAATATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACAGGACGATATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgatgatgatgacgatgaaggCGGTAACATTGCCAAAAAGATGAGACTCGAtgatagcagcaacaacagcagcagcatcaacatgaGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTTAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGTTGCCAATCGCATGACGCCCAAATCGCtgacaataacagcaacgcCACCGCTGGAGacaacgacgtcaacaacaactgcagctggagttgcagcagtggcagcatcatcatcaggaGCAGTTgcctcaacagcaacagcatcaggaTCAGGCTCATCATCCGGCAACTTGCCGCCAGCAATGGTGCATCAGACGGCACAGGAGCAGGCGGTATTCCGTCGCAGCCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGCATTTGTCAGCGCAGATTCAGTTCGAAGAAATCGTATCGCTACCACATGCTCACCGACCACCAGGTGCACAATGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTTGCCTACGAGAAGGGGCTCAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATTAAAGACGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACCGTCTACAGTTCCGAGCTGGaattgcagcagcacaagcgCAGCGTACACAAGTCACACGCCAGTGATTCATCATCAACTGcagctggtggtgctggtgctgctggcaaATCATCATTGAAATCTGCTACTGCAACTACCTCATCGACAGCTGAGCTAGTCGCAGACACATCATCCTCCTCGGGCACGGGGGCTGCGGCCATTTTGCTGCCACTTTACTGGTACCAGTGCAAATATTGTCCATCCAATTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGTGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcagcagcagcaacaacaacagcagcagcagcagcaacaacagctgcagctgcaacatcaTCAGCGACTCATCTTTAAGCACAAAACGggagatgatgatgacgaggaggaggacgatGATCAGTTGCTGCTAATGGACGAtggcggtggcggcagcaATGATAGCAATGTTGGCaatgcatcagcagcagcggcagcagcagcagcagcagtcacaatAAATACGAGCACAATGAAGATACGCATTCCGGAGGTTGCATGCACCATTTGCGGTGCCCGTTTCACCGATCAGGAAATATTCACCAAGCACATACAGAAACACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCGATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGGTTGAGCACCAGAACGAGAATGGGGAATACGCGTGCGATTTGTGCACCAAGACGTTCCCGCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCAACCAACGACGGCGAAGCGACAACGctgaacaacagcagcaacaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCGGTGGGCCTGATGcccaatcagcagcaacaccagaaacaacaacagcagcagcaacagcagcagcaaaatcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAATGCGAATACTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAACCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGACGTGTCGCCGTTGCGGCGATCTACAATTTGATACCAAAGAGCAGTGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCCACCAAGCCACCagcaccggcagcagcagcagccaataaaactgcagcggcagcagcagcagcaacaacaacaacaacagcggcaacaacaccaacagttGCCTACGGAGCAACACATGCAGCTGCtaagtcagcagcagcagcagcaacggcggcGACGAAGTCAACGACAACAGTAGCAAAAAAACTGAAGGCTaaacaagagcagcaggaGGATGATGACCTGCAGCTGGATGATGAGAAGCTaacgaagcagcagcaacaggaggaggaggaggatgataGTGATATGGATGATGATAGCGATAGTGGCAATGATGAGGAGGGCAGCACCAGtgctgacgatgatgataatgatgacgatgatgatgaggagggcgatgtcgatgacgacgatgatgatgatgacgaagaagaagacaacgacaatggtgaaaatgttgttgcacagcagcaaatactgcaacaacagccccaaaatacaaacaccaataacaacaacaacaacaacaacagcagcagcgctatTGAAAATGACGATGATCTCATTGAGGAGGTGATCGAGGACGATGGCATTGTCGAGCAGCTGGacgtcgatgatgatgaggaagacgatgatgacgatgacgacgatgacggcgatgatgatgatgatgatgatggcgaagacgatgacgacatcgatgaggatgaggatgaggatgatcAGCCGAGACGTCACAATTTCGACTACTCGCGCACCGCCAGCGCCAAGCTAAATGGCAACGGTGGCAAACAGTCTGTGACAAAATCAAAGACACAGccacagttgcaacaacagttgcagacACAGCCAATGTTGGTCATGCACAGTAGTAGCAGTCGCCACGTGAATGATGGCGAGGAGGAGGTGGATGATAtggatgatgatgttgatgacgatgatgttgTGGGTGAAGCGATGACCATTGATGATATTATTGAAGAGGATGATGGTGTGGATGATGACGATGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgatgatgacgacgaagatgatgatgacgacgatgaggatgatgatgttgaGGAGGGCatggacgatgatgatgatgatgatggggaCGACGACGATGCCGATTTCAACAACACCAATATTGGCAACGGTGTTGGCCGTGTGGGTCGAGAAGatgctgatggtgatggtgatggggatggtgatggtgatgttgatgttgatggtgGTACATCATCATCTGAGAGCGAGTCGACAACAACATCGCATTCAACTGGAGATACTTCAGACACATATTAA
Protein Sequence: MDNSGRSPSHDHPTIKWYTDGSLTNQGTGLGVVGPRVFYHESLGTHTSIFQAEITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRHWLETDKTKQQTLLGYLDLNRAENGSTIEQQQQQQQQQQHDLKMDSATSAAEKASAANILDGIPQLKKRKSLTVYVSPSPKQQQQAQQQQSQQHSQQQHATGARSTTKTSAAAASVAESQQTLQTLLLQAPTAAAAAATLATSSTQQQQQQRKYQQQLQQQRGKQQQHQYHQQQQRQSRVRQPRRQQQAATSKFRSKLYVPLDISVPALPELLPPPPPAVADAASLPLPLSLPLDFSQNPNPNPNPKQNLNQRYTSSVLVPQPQTPPMPLPPPVATMSSNEAAIGGATATATAVTTPLLMPPLPAVPIKDEPQDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATRAAAGGNISAQKYRQVVMNTFSKCENGGFDYDNPEQYQQLLSHDKIDFIQENSEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVYANVNANANAPSTSTAAATTAVHQQQQLMTANETAATTTSTTSTDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASSTATTSGLDHSSGKRSLLGALGIGIVSQSSNDESRSSNSNNHNNNNNNNSNNNNNNAPLTSTPKLPIVTGAATAGGGGGAAATSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDDEGGNIAKKMRLDDSSNNSSSINMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAVANRMTPKSLTITATPPLETTTSTTTAAGVAAVAASSSGAVASTATASGSGSSSGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVHNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSHASDSSSTAAGGAGAAGKSSLKSATATTSSTAELVADTSSSSGTGAAAILLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQQQQLQLQHHQRLIFKHKTGDDDDEEEDDDQLLLMDDGGGGSNDSNVGNASAAAAAAAAAVTINTSTMKIRIPEVACTICGARFTDQEIFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVEHQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQIPTNDGEATTLNNSSNNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQQQQQQQQQQNQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLQFDTKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPPAPAAAAANKTAAAAAAATTTTTAATTPTVAYGATHAAAKSAAAAATAATKSTTTVAKKLKAKQEQQEDDDLQLDDEKLTKQQQQEEEEDDSDMDDDSDSGNDEEGSTSADDDDNDDDDDEEGDVDDDDDDDDEEEDNDNGENVVAQQQILQQQPQNTNTNNNNNNNNSSSAIENDDDLIEEVIEDDGIVEQLDVDDDEEDDDDDDDDDGDDDDDDDGEDDDDIDEDEDEDDQPRRHNFDYSRTASAKLNGNGGKQSVTKSKTQPQLQQQLQTQPMLVMHSSSSRHVNDGEEEVDDMDDDVDDDDVVGEAMTIDDIIEEDDGVDDDDVVGVGGGVVEDDDDDDDEDDDDDDEDDDVEEGMDDDDDDDGDDDDADFNNTNIGNGVGRVGREDADGDGDGDGDGDVDVDGGTSSSESESTTTSHSTGDTSDTY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00596083;
90% Identity: iTF_00486003;
80% Identity: -