Basic Information

Insect: Drosophila villosipedis
Gene Symbol: ham
Assembly: GCA_035043025.1
Location: JAWNNF010000023.1:11161525-11186000[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.54 35 5.0 0.0 2 21 316 335 315 338 0.87

2 9 0.0081 0.52 10.8 0.1 1 23 345 368 345 368 0.92

3 9 1.7e-07 1.1e-05 25.5 1.7 1 23 374 397 374 397 0.96

4 9 3.2e-07 2.1e-05 24.6 1.5 1 23 403 425 403 425 0.97

5 9 8.2e-05 0.0052 17.0 3.8 1 23 431 453 431 453 0.97

6 9 0.0018 0.12 12.8 2.0 2 21 461 480 460 481 0.94

7 9 6.3e-09 4.1e-07 30.0 1.3 1 23 974 996 974 996 0.99

8 9 3.4e-07 2.2e-05 24.5 0.9 1 23 1002 1025 1002 1025 0.97

9 9 4.3e-05 0.0027 17.9 6.8 1 23 1031 1053 1031 1053 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.54	35	5.0	0.0	2	21	316	335	315	338	0.87
2	9	0.0081	0.52	10.8	0.1	1	23	345	368	345	368	0.92
3	9	1.7e-07	1.1e-05	25.5	1.7	1	23	374	397	374	397	0.96
4	9	3.2e-07	2.1e-05	24.6	1.5	1	23	403	425	403	425	0.97
5	9	8.2e-05	0.0052	17.0	3.8	1	23	431	453	431	453	0.97
6	9	0.0018	0.12	12.8	2.0	2	21	461	480	460	481	0.94
7	9	6.3e-09	4.1e-07	30.0	1.3	1	23	974	996	974	996	0.99
8	9	3.4e-07	2.2e-05	24.5	0.9	1	23	1002	1025	1002	1025	0.97
9	9	4.3e-05	0.0027	17.9	6.8	1	23	1031	1053	1031	1053	0.98

Sequence Information

Coding Sequence: ATGTTATTCGATCGTTATGTTATATCAGGCTCTAACGGTGACGATTACGATCCGAGCGTCGTGCgccatcatcaccatcatcatcaccacTTGGATCTCAGCAGTGGAGCGCCGGCATTTGCACCATTGCCGCCGGCGCATCTAACCTCCGGTCAGACGAGGCCCGAGGAATCGTTTGGTCGCCACCTGCCGCCAACGATATCCCCGCCACCAGCAACcctccagcagcaacagcagcagcagcagttgcaacaacagcaacagctgcaacattcACCGCCCACGCTGCCACCTGCCTCAGCGTCCGCCTCCAACGGTTCCAGCATGGAGCATCTGTTCAATGACAAGGCGCAGACGGAACGCTTTCTGCTGGAGATGGCGCGTCTTCGCGAACCCGTCTGTGATCTGGATATACGTGATACTGGCGTCTATGCCAAGACACATCTGCCCCGAGGCACCCGCTATGGACCCTTCCCCATGCGACTCTGCCAGCAGCCCAGCGATCGACACTTGGCCTGGGAGGTGAGTGCCGGCCCATTGTTTCACGGTTGGCTGGAACCCTCATCGGATGCTAATTTAAGGAATTTCATCATTGCCGGCTAtCTGTGGTACGAGACGAAACGGGACGTAAATGCTGGCGCTGAAATTGTTGTCGATGCCCGTCCGAAAACCCCGTACGATATCGGcgacagtttcagtttcaacgGGGCAGGGGCTGCCGGCGGCGCGGGCAGTGCAACATCGGCGGGGgccagcagcacagcagccgctgcagcggcagcagcagcagcaactgcaatggcagcggcagcaacatccagcaacaacaacaacaatggttcGTTGCCAGGCGATGATCGCAGCGATCGTGATAATGGCTTTTATAGCGGAGACGAGAAGAAAGGCGACAACGATTTCACGGACGACGAGAACGGTTTCGATATACGCTGTGAGGTGTGTGATAATGTCTATACGGATTTAGAACGACTGGACGATCATTTAGTGGGCGCACATCATTTCAAGCGCGGAGAATTCCCCTGCGAGCTTTGTGCCCAGCGTTTCAGCCATCGTCCTTTGCTAATCAAGCACGGAGCCATCGCCCATAATAATATACGCAAATATTCCTGCGAGAACTGTTCAAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCATCCGTGTCCGGAGTGCGGTAAAACCTTTGCCACATCATCGGGCCTCAAGCAGCATCAGCACATCCACTCATCGGTTAAGCCGTTCGCCTGTGAGGTGTGCTTCaaggcgtatacgcaattctCCAATCTGTGCCGCCACAAGCGGATGCACGCCGACTGTCGCATGCAGATCAAGTGCAAGAAGTGCAACACGAGCTTCAGCACGGTCACCTCGCTGTCGAAGCATAAGAAGTTCTGCGATACCTCGGACAGTTTtcgcagccagcagcagagtcGCCTGCAACACGCCCACGATCGCCACCatcaccagcatcagcatcagcatcatcatcagcagcagcagcaactgtcgCAGCATACGCAGCCGCCGTCACTTCTGTTGCCACCCGGTGCCCATCAGCGACTTGCCGCCGAGACGTCAAATTCGGCCATGGCCACGCCAccaaataacatatttatgatGCATCCGACACCGTCGTTCTTTGCTGGCTTTCCCAATTACGGGCTGCATGGTTTATTTCCCGGCTTCCAGCAGGCTGGCAATTTTCCGCTATCACACATGTTTCCCAATTCGCAGCTGGGCGATATGAGTCGCGGCATGCCGCCAATTGTCTCCCCAACTGCGGCATTCCAACAGCGGCTGCAGTCAGCGATGAGCATGAAAACCGAATCGCCACGTTTGAAACGCGACTCCAGCACACCGGAGCGTAAGCCCATCAAATCGGAGCTGCATCCCTCCGACGAGGAGTCCAATTCGCTCAGCTACGAAGAGCTCAAGCTGAATTCGAGCAAGTTGCAGCAGGAGTCGGGCAAGGTGAAGCGGGAACTTAAATCGGAGGCCAGTTGCACCCAGCAAGCCGACGAGGACACCGATCATAATAATAGTGACAATGATAACGATAATGATATTGAAAATGATAGGAAATCGATTGACATTGTTAGCACTCCGCCGCCAGCGGAAACGCAAATGAAGACCGAACCGGAAACGGCGGATGTGGACAAGAGCAGCGCTGAGCTGCCGCTAGATTTGTCCATCAGTCGCAAGCGTCGCAGTTCGCTGTGCGCTGCCTCCACGCCCGCCCCGCCCTCCATATCTCTGTCGAGTCGCGAGCCATCGCCCGAGCTGGACGCCGATGAGGACGAGGAAGAGGATGAGGACGAAGTGGAGCTGCTGGCGCCGCCGGCAAAGCAACCAAAGCACAGTTCCGGCGAATCGAGCACTTCCCGTCAGTCGTACAAGGGCAGCAGTCCGGTGCCAAGTGCGAGTGCCTCTCCCGGACCAACACCTTCACCATCGCCACCCATCAGCACTGGCGGCGAGTTGAGCAGCATGTCGGAGAGTGCCGCTGCGaatgcaacggcaacggcaacggcatcggcagctgccgcagccgcagcagcagcggccgccTCAGCGATGGCCTGTCCCCGGCAACTGCatccgcagctgctgctggaggagcTCTACCGCTCGCGATTCCCAACGCAGCCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGTCACTAAAGTCGTCAGCGATGGGTGCCGCACATGCGCCCATCAGTGGCGGCGGCTCGCGTCATCTGCCGTTTCCGCCCGAGCATAATTTCCATGAGGCACTCCGTGCCGCTGGCTTGGCGGCCGCTGCCGCCCGTCCGCCGACAGCGTGCAACGCCAGTGGCAAGCTGAAGGATCGCTATACGTGCAAATTCTGTGGCAAGGTGTTTCCACGTTCCGCGAATCTAACACGGCATCTGCGCACCCACACTGGCGAACAGCCGTACACGTGCAAGTATTGCGATCGTGCCTTCAGCATCTCATCGAATCTGCAGCGTCATGTGCGCAACATCCACAACAAGGAGCGACCATTTCGCTGCCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCACCTAAAGAAGCATGAGGCAGATGCTGGCGGCTTCGAGTACAACGATTCGCCCAGTTCGAATGAGGCAAATGATCGCGATGAGGCCTGCTTCGATGATATCCGTTCGTTTATGAAACGCGTCTATACGCCCACCAGTTTGGGCGGGGCGGATGGTGATACGGAGGAGTATGCGGGCAGTGATGATCAGTTGTCCGTTTCTACGCGTCAGTCTGCCAACTTTGACAAAGAGCTGCTCTCAAAtggcaacatcatcaacatcaacaacaacaatagcagcaacaataacaacaacaacaatagcaacaacaacaatagcaacagcagcagcaacaatcagaCTTTAAATACATCGGAAACAATTGCCGTGAGCACCTAA
Protein Sequence: MLFDRYVISGSNGDDYDPSVVRHHHHHHHHLDLSSGAPAFAPLPPAHLTSGQTRPEESFGRHLPPTISPPPATLQQQQQQQQLQQQQQLQHSPPTLPPASASASNGSSMEHLFNDKAQTERFLLEMARLREPVCDLDIRDTGVYAKTHLPRGTRYGPFPMRLCQQPSDRHLAWEVSAGPLFHGWLEPSSDANLRNFIIAGYLWYETKRDVNAGAEIVVDARPKTPYDIGDSFSFNGAGAAGGAGSATSAGASSTAAAAAAAAAATAMAAAATSSNNNNNGSLPGDDRSDRDNGFYSGDEKKGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFPCELCAQRFSHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDTSDSFRSQQQSRLQHAHDRHHHQHQHQHHHQQQQQLSQHTQPPSLLLPPGAHQRLAAETSNSAMATPPNNIFMMHPTPSFFAGFPNYGLHGLFPGFQQAGNFPLSHMFPNSQLGDMSRGMPPIVSPTAAFQQRLQSAMSMKTESPRLKRDSSTPERKPIKSELHPSDEESNSLSYEELKLNSSKLQQESGKVKRELKSEASCTQQADEDTDHNNSDNDNDNDIENDRKSIDIVSTPPPAETQMKTEPETADVDKSSAELPLDLSISRKRRSSLCAASTPAPPSISLSSREPSPELDADEDEEEDEDEVELLAPPAKQPKHSSGESSTSRQSYKGSSPVPSASASPGPTPSPSPPISTGGELSSMSESAAANATATATASAAAAAAAAAAASAMACPRQLHPQLLLEELYRSRFPTQPFHFLGQMGGRPGFESLKSSAMGAAHAPISGGGSRHLPFPPEHNFHEALRAAGLAAAAARPPTACNASGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDRDEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRQSANFDKELLSNGNIININNNNSSNNNNNNNSNNNNSNSSSNNQTLNTSETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01327310;
90% Identity: iTF_00513601;
80% Identity: -