Basic Information

Gene Symbol
hang
Assembly
GCA_018150405.1
Location
JAECWK010000126.1:12279912-12289177[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.21 19 5.7 1.0 3 23 474 495 473 495 0.93
2 19 0.26 25 5.4 3.2 3 22 603 622 601 622 0.89
3 19 0.00044 0.042 14.1 3.3 1 22 722 743 722 745 0.90
4 19 0.66 62 4.1 0.2 2 23 757 779 756 779 0.94
5 19 0.00051 0.048 13.9 0.2 2 23 915 937 914 937 0.95
6 19 0.0015 0.14 12.5 0.1 1 23 945 968 945 968 0.96
7 19 1.2e-05 0.0011 19.0 0.1 2 23 1059 1080 1058 1080 0.97
8 19 0.00021 0.02 15.1 2.9 2 23 1165 1187 1164 1187 0.97
9 19 0.017 1.6 9.2 0.2 2 23 1196 1218 1195 1218 0.95
10 19 0.0016 0.15 12.4 0.1 1 23 1231 1254 1231 1254 0.97
11 19 9.2e-05 0.0087 16.3 1.1 1 23 1310 1332 1310 1332 0.99
12 19 0.0014 0.13 12.5 0.9 1 23 1340 1363 1340 1363 0.96
13 19 0.56 53 4.4 0.3 2 19 1371 1388 1371 1389 0.93
14 19 1.9e-05 0.0018 18.4 0.4 3 23 1494 1514 1493 1514 0.98
15 19 0.0037 0.35 11.2 0.1 1 23 1551 1573 1551 1573 0.97
16 19 4.5e-05 0.0043 17.2 0.6 2 23 1665 1687 1664 1687 0.93
17 19 0.34 32 5.0 0.0 3 20 1708 1725 1706 1727 0.91
18 19 0.0049 0.46 10.8 0.4 3 23 1742 1762 1742 1762 0.98
19 19 7.5e-05 0.0071 16.5 2.1 1 23 2065 2087 2065 2087 0.98

Sequence Information

Coding Sequence
ATGAACAACATATTATCGAAAAGGGAATGGAATGAAATGGAGGAGGCGGCGGCGGAAAGGATCACGTCGCAGGACCGATTGTCCTTGCAGATCTGCCACGCCTGCATCAGCTACCTCAACTCGTGGCAGAGCTTCAAGAATCGCTCCCTCATCTCGCAGACCAAGCAGCGCCAATGGCTGGAGGCGAACAACAGCAGCAAGAGCAAGTTGCTCAACTACCTGGACCTGAACAGTGCAGAGAATGGCTCTGATCCACACCAGCACCAACAACAACAACAACACCAGCAGCAGCAGCATCAGGATGAAACGGACAGGAGCCCGACGATGTCAGGAGCAGCAACAGCCTCGGCGGCTGCCATTTTGGATGGCATACCCGCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCTAAACCGCAACAGTTGGCACAGTTGCCACCACCACCACCACCACCACTTCTACTACCACCACCACCACCATCGTTGTCGTCGTCGTCGTCGATGAACAGCAGCAGCAGCAACAGCGCCGCCCAGCAGCCCAGTCTGCAGACCCTGCTCCTGCAAGTGCCAGGCGCAGCAGTGGCCAGCTCTTCCGCCACAGTCACAGCTTCCCTATCCGCTTCCTCCTCCCAGCCGCATCGGGATCGGGAGCAGCACAGGCACTATCGCAGGCATCACCATCACTCGCAGCAGCAGCAGTTGCACTTCCAGCGTGGCAGGCATCACCATCATTACCACCACCAGCAGACGCACCATCACCAGACGCATCCGCAGGCCCAGCGCCGCCAGAGGCAGCTACGTCCAGGGATACAAGGACGCACCACGTCCGCCACCGCTTCCTCGCTGCGGAAATTCAAGCCGAAGCTGTATTTGCCGCTGGATATAACAGTGCCACCACTGCCACCGCTTCCAGTGACTGCTGCTCCTTCTGTTTCTGCTGCTCCTGCTCCAGCTCCAGCTCCTCCACCACCCCCACCTCCGCCGCCTCCACCTTCGGCAGTGGCTAGTGGCAGGGAGAGCTTGCCTTTAGATTTCAGCCAAGCTGGCTGCATCAGCGGTGCCCTGCACCTGCAGCAACAGACCACTGTGGCTAGTACTGCAACCGCAACTTGCACATCCGCCTCTGCATCCGCTTCCGCATCTGCTCCATTGCTCATGCCGCCACTGCCAGCGGTGCCCATTAAGGATGAGCCCATAGACACGGATGACGACTACCAGATGAAGTCGATCGACGAGTCCGATGACATGGTAGACCCCACAATGTTCCTAGAGCGTTCTGAGCTCGAGGGCGATATGCCCTTGATGACCTCCGACTATGACTACACGGCCCAGCATGCCGCCTCTGCGGCCGCCAACCTGCCACCAAATGCAGTGGCCAATGTGGCCGCCGCCGGGGACTCAAAGGTGGCTAGCTGCCGGGCCTGCAGCCTGCAGTTCTCCACGCGCGCCAATGCCCGACGCCACGAGCGCAACCTGCACCCGAATCTGTTCCAGCTCTCCACCGACTCGCCCCACAACACGCCCATTACCAAGCCCACGCCCGCCCTGGCCGCCGCTTTGGAAATCCAGCGGGCAGCGGCCGAAGCAGCCACCGCCGAGGCCAACCGGGCAGCCGGAGCAGCTGGTGGGAACATCTCCACGCAAAAGTATCGGCAGGTGGTGATGAACGCCTTCATCAAGTGCGAGGGCGGCGGCTACGACTACGAGAATCCGGAGCAGTACCGCATCCACCTCACCCGCGACAAGGTGGAGTTCATCGAGCAGAACGAAGAATTCCTGGAGCAATACCAGACGATGACGTGCCGCTGCTGCAACAAGTACTTCTCCACCTACAAAAACTTTATGGCCCACGTGCGCAAGAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCAAAGGCCCTGTTCATCTCGCATCTGAAGAAGAGGAACTGCATCAACCTGTATCGGGTGCTCAACGCCATCAGGGACAGGGCAGCCGCCAAAGATGGAGCTCTGGGGGAGGCGGGTGATGGCAGAGTCGCCCACCTGGACGCCGCTTCCAGTCCCAGTGTCGCCGCCGATATAATCTCCAGCACTCCCGGATCGGAGCGGCCGGAAAAGTTGCGGGCCAAGGAGCTGCTGGTCAACAAGCTGTACGAGTGCAAGCTGTGTCCCAAGGGCTTCCGCACCAAGCACGAGTTCCGCACCCACGTCTACGACAAGCACGCCGATGTCCAGCGCAAGGACAGCAACTCTACCCAGTGCAACTTTTGCGGCTTGGACATTGCCGATCCGGTGGACAGGCGGCGGCACTACAACAATATGCACTGCATCGTCCGCCTGCGCTGCATGACCTGCGACGCCAAGCTGGAGACGCACCAGCGCTTCCTCGACCACGTCTACCAGGACCATTTGGGCGGCGTGGGCGGTGGCGGCGGCACTGGAGGCGGCGGCGTTAGCAGCGACAACGCCTCCACCACGGGCAACAGCATGGAGCACTCGCCGGGCAAGCGCAGTCTGCTCGGTGCCCTGGGCATTGGCGTCGGCTCCTCAGCGGAGGAGTCGCGCAGCAGCAGCGGCGCTCTCGGGCCGTTGACCTCCACACCCAAACCGGGTGGTGGTTCCGGTTCCGCCTCTGGATCTGGCCAGCAAACCTCCAATCCTACTGGTGCTCCTCCTGGTGGCGGCAATGGCTCGGCCCCCAAGTCCCAGTACTTCTCCCGCATGCCGCAGGTCTGCCCCATTTGCGGCCAGCAGTACAACAACTACAACAACGTGCTCCGCCACATGGAATCGAAGCATCCGAACAAGCTGCCCGAGACGTACAAGTGCGTGAGGTGCGGCCTGGGCTATCCGAGGATCTCCTACCTGCGGGAGCACATGATCAACGTGCATGGCGTGGACAAGAATCGGCATTCCGGCGGCTTCGAGTATATCGTGAATGCGGATGCCGTGAAGCTGGCGGATGGCAGTACTCCCAATGTCTACACTGGTCGCTACGACTACGTCATGAAGGACCTCATGTCGATAACAAATGGTGGGACCCTCGATGACGACGAGGACGAGCCGGGCAGCGTGGCCAAGAAGATGCGCCTGGACGACAGCAGCAACAACAGCAGCCTGGCAGGAGTGGGCGTGTCCAGCCAGCAGCAGCAGCAGCAGAAGGAGTGTCCCATCTGCAACGCCGTCTTCAGCAACAACATTGGACTGTCCAACCATATGCGCTCCCACTACACGGCCTCCAATGCGGTGAACGCGGCCCTGACAGCGGCCAATCGCATGACGCCCAAATCCCTGACCATAACAGCTACACCATCGGCGCCGGCGGCGACGGATACCACCATGGAGCTTCTGACTGGCTCCTCGGCCCCGGCTACCTCGGCTCCCGCCGTTCCTCCAGCCATGGCCAATCAGACGCCGCAGGAGCAGGCGGTATTCCGGCGCAGTCTGGACCAGGCGGCCGACCGTCGCTTCCGCAGGATGCGCTGCCGCATCTGCCAGCGGCGGTTCAGCTCGAAGAAGTCCTACCGCTACCACATGCTCACCGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAATGCGGAGTTCGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGCAGGGCCATCAAGGACGAGATGATTGTGAAGCAGTTCGAGTGCGAGGTGTGCTCCATTGTCTACAGCTCGGAGCTGGAGCTGCAGCAGCACAAGCGCAGTGTCCACAAAATGTCTGCCGCCTCCTCTGCCTCTGCCGGGGGCGCTGCGGCCAAACTCGAGGACGACAGCCTGTTCCTGGAGGACAGCACTCTCAAGCCGGCCGCCGGCGACCTGACGGATGCTTCGATGAACGCCTCGGGAGCCGGAGGCCTGGCCACGCCCTTGTACTGGTATCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATCCACATCAACTCCCACGACGAGTTCGATTCGAACGATTACTCCTGCAAGGATTGCGGCAATGTCTACAGCGGACGCAAGAGCCTATGGGTTCATCGCTACAAGAAGCATCCGCAGGTGCCAGATCCGGCAGAGTGCTCGCTGTGCCGCAAGATCTTCTTCGATCGCCAGATGCTGGACAACCACACGCCCACCTGCAACCGGAAGCCGATCACCTCGACGGGCGCCCACCAGCAGCACCAGTTGCAGCAGCAGCAGATGCAGGAGGCACTGCACCAGCAGCACATCGCGCTCCAGAAACAGGTTGGCCTGCACTCGGGCGTGTTCCGGCACAAGACCGGCGACGATGACGACGAAGAGGACGAGGACGAGCAGCACCTGGGCGACACAGCCGTAGAAAGTGGTGCAGTCGGTCCGGCATCGGTGCCGGCTCCTGCCGCTCCGGCTGCCGCTCCAGCTGCGGCGGCTGCCTCGATCAAGATACGCATTCCAGAGGTGGCGTGCACCATATGCGGGGCCCGTTTCACCGACCAGGAGATGTTCACCAAGCACATCCAGAAGCACGAACAGGAGCTGTACGTGGACAATCCCCTGGCGGCGATGTTCGACGATGGGCCGCCAGATGCCGGCCAGTTTCAGGTGGAGCTGGAGAAGCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTTCCGCAGGTCATTGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCGACGGCGAAGCGACACATTTGACCAACAACAATCACACCACCAGCAACAACAACAACAACAGCAGCTCGATGCTACACCTCCGCGAGCTGCATGCGGTGGGTCTGATGCCCAACAACCAACAACACCAGATGCAGGACCAATCGCAACAGTCACATCTCGCCCAGCAGCAGCAGCACCACCACCACCAGTACCAGCCGGGCAACGCGAATCCGAACAAGTCGATGAAACGGAAGCGTGAACTCAAATGCGAATACTGCCCCTCCACCTTCATCAGCAACAACAATCTGCGCCGGCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTACCGGAGCCACCGGTCATCGTGGTGGACGATCATTTAGCCTGCCGCCGGTGCGATCTCACCTTCGCCACCAAGGAGCTGTGGATCGATCACAAGCTGGCGGACGCCAAGGTGGTCCGGCCGTTCTGCCCCTTCCAGTGGGGCTGTGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTCATGAATCACATCAACAACCATCTCAAGGAGGAGGTAATTGTGCCGGTGGCCACCAAAGGGGCGGTGGACAGGGTGGCGGCGAAGCCACACGAGGCGGAGGAGGGAACGGAGGCGGCAGCAGCAGAATCCAACAGGGCCGGGGCAAAGGAGGAAGCGGCCCTGGATAAATCGAAGGCGGATATCCAGTCTCAGTCCCAGGCCAAGGCCGGGCAGCCGGACAGCGATGACTTGGACGAGGATAGCTCCGGCGAGGAGGAGGAGACCTCGGGCACGGGCGATGACGAGGGCGACGACGATGATGATGAGGACTCCGAGGAGGATGTGGAAGACGAGGACGAAGAGGGCGACGGCGGCGAGGGCGAGGACGAGGAGGGCGTGCCGCCGCAACAGCAGCCACCGAAAATGAACATTCCCCAGGACGATGATCTGGTTGAGGAGGTCCTCAGCTCCGACGACGATGTGGAGAGCGACGATGTCGACGAGGACGACATCGATGAAGAGGAGGAGGAGGAGGAGGATGATGTGGAGGATCCTCAGCCTGTGGTGATGAATGGCAAGCCGAAGATACCGCCACTAATTGTGGCCGATTCGGACGAAGAGGAGGAGGAGGAGGATGAGGAGGAGGAGGAAGATGTTGGCATGCTGCCCATTGAGGACATAATCGAGGAGGAGTTTGACGAGGACGCGGCCGATCCAGAGCCGGACGACGATCTGGTCGAGGAGGATGAGGGGGAGGAGGAGGTTGAGGAGATTGAAGAGGAAGAGGTAATCGAAGAGCTAGACGATGACATGGTGGAGGACGAGGTCGAGGAGGCCAACGAAAGGCGCAACTCGTCGTCGGCCAGCGAGTCGACAGCCACCACGACCACGTCGCAATCACATTCCACGGGTGAGCAGCGGCCCAAGAAGCCGCCGGCGCTGCCAGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTACTCCAGAGCCACATCAAAAGCCATTTCCTCAATGGTCCAAAACTGGCCAAAGCCGCCGGAGCATCGCCATCGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCTCCAGTCCATTCGCCATCTCACTTGAAAATGTACAAAGAACCTAG
Protein Sequence
MNNILSKREWNEMEEAAAERITSQDRLSLQICHACISYLNSWQSFKNRSLISQTKQRQWLEANNSSKSKLLNYLDLNSAENGSDPHQHQQQQQHQQQQHQDETDRSPTMSGAATASAAAILDGIPALKKRKSLTVYVSPKPQQLAQLPPPPPPPLLLPPPPPSLSSSSSMNSSSSNSAAQQPSLQTLLLQVPGAAVASSSATVTASLSASSSQPHRDREQHRHYRRHHHHSQQQQLHFQRGRHHHHYHHQQTHHHQTHPQAQRRQRQLRPGIQGRTTSATASSLRKFKPKLYLPLDITVPPLPPLPVTAAPSVSAAPAPAPAPPPPPPPPPPPSAVASGRESLPLDFSQAGCISGALHLQQQTTVASTATATCTSASASASASAPLLMPPLPAVPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSELEGDMPLMTSDYDYTAQHAASAAANLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAEAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYENPEQYRIHLTRDKVEFIEQNEEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNAIRDRAAAKDGALGEAGDGRVAHLDAASSPSVAADIISSTPGSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDSNSTQCNFCGLDIADPVDRRRHYNNMHCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGGGTGGGGVSSDNASTTGNSMEHSPGKRSLLGALGIGVGSSAEESRSSSGALGPLTSTPKPGGGSGSASGSGQQTSNPTGAPPGGGNGSAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEDEPGSVAKKMRLDDSSNNSSLAGVGVSSQQQQQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALTAANRMTPKSLTITATPSAPAATDTTMELLTGSSAPATSAPAVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECEVCSIVYSSELELQQHKRSVHKMSAASSASAGGAAAKLEDDSLFLEDSTLKPAAGDLTDASMNASGAGGLATPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAHQQHQLQQQQMQEALHQQHIALQKQVGLHSGVFRHKTGDDDDEEDEDEQHLGDTAVESGAVGPASVPAPAAPAAAPAAAAASIKIRIPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPPDAGQFQVELEKQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATHLTNNNHTTSNNNNNSSSMLHLRELHAVGLMPNNQQHQMQDQSQQSHLAQQQQHHHHQYQPGNANPNKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLACRRCDLTFATKELWIDHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKGAVDRVAAKPHEAEEGTEAAAAESNRAGAKEEAALDKSKADIQSQSQAKAGQPDSDDLDEDSSGEEEETSGTGDDEGDDDDDEDSEEDVEDEDEEGDGGEGEDEEGVPPQQQPPKMNIPQDDDLVEEVLSSDDDVESDDVDEDDIDEEEEEEEDDVEDPQPVVMNGKPKIPPLIVADSDEEEEEEDEEEEEDVGMLPIEDIIEEEFDEDAADPEPDDDLVEEDEGEEEVEEIEEEEVIEELDDDMVEDEVEEANERRNSSSASESTATTTTSQSHSTGEQRPKKPPALPGFTCDLCQLCFDSQELLQSHIKSHFLNGPKLAKAAGASPSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSPFAISLENVQRT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00550380;
90% Identity
-
80% Identity
-