Basic Information

Insect: Drosophila varians
Gene Symbol: -
Assembly: GCA_018150405.1
Location: JAECWK010000130.1:7440728-7444174[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0043 0.4 11.0 2.9 2 23 317 339 316 339 0.96

2 18 0.39 36 4.9 0.4 1 23 346 371 346 371 0.91

3 18 0.021 2 8.8 2.2 2 23 382 403 382 403 0.93

4 18 0.02 1.9 8.9 0.4 3 23 444 465 443 465 0.95

5 18 0.00051 0.048 13.9 0.5 3 23 473 493 471 493 0.95

6 18 0.011 1 9.7 0.2 1 23 501 524 501 524 0.97

7 18 0.00032 0.03 14.6 0.3 2 23 529 550 528 550 0.97

8 18 1.5 1.4e+02 3.0 0.1 2 21 559 578 559 579 0.90

9 18 0.00035 0.033 14.4 2.8 1 23 598 622 598 622 0.91

10 18 0.034 3.2 8.2 1.8 3 21 629 647 629 648 0.90

11 18 0.0036 0.34 11.3 0.3 1 23 667 692 667 692 0.96

12 18 0.17 16 6.0 1.7 2 23 710 732 709 732 0.94

13 18 0.0017 0.16 12.3 0.2 2 23 738 760 737 760 0.92

14 18 0.011 1.1 9.7 0.2 2 23 764 786 763 786 0.95

15 18 1.8e-05 0.0017 18.5 0.9 1 23 792 814 792 814 0.97

16 18 0.003 0.28 11.5 1.0 1 23 818 841 818 841 0.94

17 18 4.1e-06 0.00039 20.5 1.4 1 23 847 870 847 870 0.97

18 18 2e-05 0.0019 18.3 0.2 4 23 877 902 874 902 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0043	0.4	11.0	2.9	2	23	317	339	316	339	0.96
2	18	0.39	36	4.9	0.4	1	23	346	371	346	371	0.91
3	18	0.021	2	8.8	2.2	2	23	382	403	382	403	0.93
4	18	0.02	1.9	8.9	0.4	3	23	444	465	443	465	0.95
5	18	0.00051	0.048	13.9	0.5	3	23	473	493	471	493	0.95
6	18	0.011	1	9.7	0.2	1	23	501	524	501	524	0.97
7	18	0.00032	0.03	14.6	0.3	2	23	529	550	528	550	0.97
8	18	1.5	1.4e+02	3.0	0.1	2	21	559	578	559	579	0.90
9	18	0.00035	0.033	14.4	2.8	1	23	598	622	598	622	0.91
10	18	0.034	3.2	8.2	1.8	3	21	629	647	629	648	0.90
11	18	0.0036	0.34	11.3	0.3	1	23	667	692	667	692	0.96
12	18	0.17	16	6.0	1.7	2	23	710	732	709	732	0.94
13	18	0.0017	0.16	12.3	0.2	2	23	738	760	737	760	0.92
14	18	0.011	1.1	9.7	0.2	2	23	764	786	763	786	0.95
15	18	1.8e-05	0.0017	18.5	0.9	1	23	792	814	792	814	0.97
16	18	0.003	0.28	11.5	1.0	1	23	818	841	818	841	0.94
17	18	4.1e-06	0.00039	20.5	1.4	1	23	847	870	847	870	0.97
18	18	2e-05	0.0019	18.3	0.2	4	23	877	902	874	902	0.83

Sequence Information

Coding Sequence: ATGTCGGAAAACCAGGAAAAACAAAGCTGCCTGCATTGTAGAGTATTCAATCCGAAATTTCAGTACCAGGATATATTCGATGAGTTTGGCACCGAGCTGGGCCTGCAATCCCTACTGGCCAAGCACTTTGACTTCAGGGTGACACAAGATTGCAGTAAAGAGCAGCGTCTCTGCGAGGTTTGCGTAAACAGTTTAATTCGCCTATTTGACATCGATGAACTGCAGCGGGAACAGGATGCGGCTAAGGATAAAACCAAGGGGCCTGCTCCTGATCAGGAGGTGCAGGCGGTTAACCCGGAAAACAGTGATCTACCACCACTACCACCTCTGCAACCAGCTCCAAAACAGGATGTTCTTCAAAAGAGCAAGACCGTAAAAACTGTACCAATCGTCCTTAAAGGAGAAACCATAGGTACCGGTAAAAAGGAACCTCCATCCCCAGCTCTTGTAGCTTCTAATACTTCTAAGGATTTTGACAAAGTCAAGAAGCTGTCAATATCCACGCCTCCCGCAAAACTACAATCTAAGGGGGTCCCAAAGGAATCGGATCAGGAGCAGATCAGCCGTCTTATATGCAACATCCTAAACGATGATGAGACGATCGTTGAGGAGGTAGCGGCTCCAATACCAGCGGAAACCGAAAAACAGAATGAATTGTTGTGCAAGAATCCTTTAGCTGACGATCTTGACCAGGAAGAATATATTTATGACCATGAAGATATCTTGGACCCGGTTTTGGAGAACTTAAAGTTAAAGCCGGAGGCTCGTCCAAAAGTGCAAGCGGAGGATAGCCAGAGTGAGGGAGATATCGATGGAAGTGAATCCAGCAATGTTGTGATCTTTAACTTTGTTGAAATCAAGGATCAAGACGATATTGGTAGCGTTTTCGAATATCTGTCCACTGTGGTAAAAACCAGCTTTGAAAAACTCTCTTTCGAGTGGATTACTGAGTGCAAACACTGTTCTACAAAGTTTCAAAATTTCAAGGCTCTCTTAAGTCATATGCTAAAGGCCCATAAATGTCGAGGCAACATTTTCAAATGTCCTTTCAAAGACTGCAGCAAGGACCTGAAAGGAAGTAAATTTCTGGCAATGCATTTGGTGCTCATGCATGCCAATCTGGTTGATATACCAATCTATGGCAGCTGCCCGGAGTGCAAAATGACATTTTCTAACATTTTACAATATAACAAACACTCCTGTGCCCATGTCATCAAAAAGAAACGAGGTATCCGGCTTTTCTGTGAGATGTGTGCTCAATGTTTTCCCTCCTGGAAGCGATTCAATTTTCACAATCAATTTCATCTGGAGAAACACAGGCCCCGCAATTGTTTCATCTGCGACTATTCCAGCAACAATATTGAAGATCTTTTCCAGCATTTGAATTACTCCCATGAGCCAGAGGGCACCCTTTTCTGTGATATTTGTGATCGCACATTCCGAGATTCTGAGGTTTTCACCGAGCACAAAATCTCCCATGCCAACGTTGGTAGCACCACCTTCTCCTGCGGCGAGTGTATGGCCATGTTTGAGTCCCGTGGCCGGTTGAATGGGCACATGAGAACCATGCATGGCAGCGCCATAAGCTGCGAAATGTGCTCCCGCGAGTTCGCCAGTGAGGCCACTTACAACATTCACATGAAGAAGCACTTGATCATAGAAAAGGATGTGAATGTTTGCAGCAAATGCGGTCAGTTGAGCGAAAACCAGGAGACCATGCTAACACATGTGAATAGTGAGGATTCCCCCTGTTTTGAAGCAAAGTTTGTCACCGAACTCCTTCGCGATGCCTATGCTTGCGAACATTGCTCGCTGAACTTCAAGGAAAAGTCGCATCTGCGTAGCCATCGAGAAACGGGAGTGCACAAGAACGGATTGTATTGGTGTCAGCCGTGTGGCAAGGAATTTTCGCATATGAAACTATACCGCCACCACATACGTAACTTTCAACAAATACGAGGAGATGCCTCCCATCGCAAGCTGGACATTTGTGTTTTCTACATGTGCGATCAGGAGGGATGTTCTGAGGCTTATGCGAATTGGAATTCCCTGTATACGCACAAGCGGCGCACCCATGAATCCTCCACCCAGCAACCTAATAAAGCCTCAAAAACGGAACAAGATTGGGTTTGTCAGTTTTGTTTAAAACAGTGTCGCTCCAAGATGTCCTTGTCGATTCATGTGGCAAGGAGTCACAATAACGACAATGTGGTCTGCCCTTTGTGTAATGCATCTTACAAGAACCAGGAAGCATTGGACAAACACCATGCCTACTGGCACGAGCCCATTGAGTGTCCCCAGTGCTTCAAAATTGTCAAAAACAGGCGGAACTATGATACGCATGTAAACGTGGTCCATTCCAATACGAAGCGCTACGCCTGCGGCGTGTGCCAAAAGGGATTCTATCACAAAAGCGAAATGGAGGCGCATCAAAGGCTCCATGGCCAGTCATACAATTGTGACCAGTGCAGCTTTACCACCAGGAACAAAAAGTCCTTGTCCGTCCACATTCTCGGCCAGCACTACAAGCGATTCGCCTTTGAGTGTAAAATGTGCAACAAGCGATTTGGTCGCCGGCAAGGCCTAAACACCCACATGCAACGTGCTCACGGGTCGAAGTTCATGTGCCGGGACTACTTTGAGGGCGGCTGTGGTCGCACCTTCATCAACAGCTCCCAGTTGAATGTCCACGTGCGGAAGGTGCACAATGGCACAATTTTTCTGACCGAGGAAGAGGAGGAGGAGTTCATCAGCGACGGTCCATCCTCGTCCAAGAAACGCTGCATTCGCATCGACGATGACACCAACATCGAGTTTATAGAGGATCCTGAAACCATCCAAGATGAAATAGAACTGGTGGATGAAATCGAAGAGGATGAATACATGGACGCGGATTTGGACAATAGCTCCATTGCCAAGCATTAA
Protein Sequence: MSENQEKQSCLHCRVFNPKFQYQDIFDEFGTELGLQSLLAKHFDFRVTQDCSKEQRLCEVCVNSLIRLFDIDELQREQDAAKDKTKGPAPDQEVQAVNPENSDLPPLPPLQPAPKQDVLQKSKTVKTVPIVLKGETIGTGKKEPPSPALVASNTSKDFDKVKKLSISTPPAKLQSKGVPKESDQEQISRLICNILNDDETIVEEVAAPIPAETEKQNELLCKNPLADDLDQEEYIYDHEDILDPVLENLKLKPEARPKVQAEDSQSEGDIDGSESSNVVIFNFVEIKDQDDIGSVFEYLSTVVKTSFEKLSFEWITECKHCSTKFQNFKALLSHMLKAHKCRGNIFKCPFKDCSKDLKGSKFLAMHLVLMHANLVDIPIYGSCPECKMTFSNILQYNKHSCAHVIKKKRGIRLFCEMCAQCFPSWKRFNFHNQFHLEKHRPRNCFICDYSSNNIEDLFQHLNYSHEPEGTLFCDICDRTFRDSEVFTEHKISHANVGSTTFSCGECMAMFESRGRLNGHMRTMHGSAISCEMCSREFASEATYNIHMKKHLIIEKDVNVCSKCGQLSENQETMLTHVNSEDSPCFEAKFVTELLRDAYACEHCSLNFKEKSHLRSHRETGVHKNGLYWCQPCGKEFSHMKLYRHHIRNFQQIRGDASHRKLDICVFYMCDQEGCSEAYANWNSLYTHKRRTHESSTQQPNKASKTEQDWVCQFCLKQCRSKMSLSIHVARSHNNDNVVCPLCNASYKNQEALDKHHAYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNTKRYACGVCQKGFYHKSEMEAHQRLHGQSYNCDQCSFTTRNKKSLSVHILGQHYKRFAFECKMCNKRFGRRQGLNTHMQRAHGSKFMCRDYFEGGCGRTFINSSQLNVHVRKVHNGTIFLTEEEEEEFISDGPSSSKKRCIRIDDDTNIEFIEDPETIQDEIELVDEIEEDEYMDADLDNSSIAKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481678;
90% Identity: -
80% Identity: -