Basic Information

Insect: Drosophila varians
Gene Symbol: ZNF212
Assembly: GCA_018150405.1
Location: JAECWK010000130.1:4669376-4672449[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.024 2.3 8.6 0.2 1 18 33 50 33 50 0.91

2 11 0.59 55 4.3 2.1 1 20 114 133 114 134 0.92

3 11 0.00019 0.018 15.3 1.1 2 23 177 198 176 198 0.97

4 11 0.00014 0.013 15.7 0.9 1 23 224 245 224 245 0.98

5 11 9.3e-05 0.0088 16.2 0.4 2 23 253 274 252 274 0.97

6 11 0.00019 0.018 15.2 0.3 1 23 301 323 301 323 0.98

7 11 4.8e-08 4.6e-06 26.6 0.9 1 23 329 351 329 351 0.99

8 11 0.00067 0.063 13.6 5.5 1 23 357 379 357 379 0.98

9 11 1.5e-05 0.0014 18.8 1.4 1 23 385 407 385 407 0.97

10 11 3.6e-05 0.0034 17.5 0.2 1 23 411 433 411 433 0.99

11 11 0.00053 0.05 13.9 0.1 3 23 459 480 457 480 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.024	2.3	8.6	0.2	1	18	33	50	33	50	0.91
2	11	0.59	55	4.3	2.1	1	20	114	133	114	134	0.92
3	11	0.00019	0.018	15.3	1.1	2	23	177	198	176	198	0.97
4	11	0.00014	0.013	15.7	0.9	1	23	224	245	224	245	0.98
5	11	9.3e-05	0.0088	16.2	0.4	2	23	253	274	252	274	0.97
6	11	0.00019	0.018	15.2	0.3	1	23	301	323	301	323	0.98
7	11	4.8e-08	4.6e-06	26.6	0.9	1	23	329	351	329	351	0.99
8	11	0.00067	0.063	13.6	5.5	1	23	357	379	357	379	0.98
9	11	1.5e-05	0.0014	18.8	1.4	1	23	385	407	385	407	0.97
10	11	3.6e-05	0.0034	17.5	0.2	1	23	411	433	411	433	0.99
11	11	0.00053	0.05	13.9	0.1	3	23	459	480	457	480	0.97

Sequence Information

Coding Sequence: ATGTCATCACCGCGCGGGTGTGAGGACGCGGCGATGAGTCCATCCATGCACGTGGAGCACGCAGTCTCCACGGAGTCCGCCACCCAGGAACTCTTTTTCTACTGCGAGCTCTGCGGTAGAGTCTACGAGGACAGTGAGGCCTTTAATAGGGACCACACTCCGCAGTCCAGTTGCTGCGCCGTTGTCAAAGAGGATGTGGATTTTGTAGAGGACCCGACAGTGGAGGAAGAGACCGAGGAAATCGTGGAAGCGGATGTGCCTCTATGGGAAGTGGTTGATGTGCCCGAAACTAGTGCCATGACGGAGCAGAACGAGACTGACCCCAGCCACTCGGAGCGCTATTTCTGCTACGACTGCCATAGCATTTTCGAAAACAGGAGCAGTGCCGAGGATCATGTGTGTCCGGGGGCAGAGCTAGCACATTCGACAAGCATTGAGTCAAATGTCGCCAGCTCTCCCAAGACATCCATCCGAAGGAAGGTTCCAACCACTAATGCAAAAACCGGTAGCAAGGCAGTGTCTTCCATCAGCTGCGACATTTGCAAAACCGTGTTTAGCTCGTCAAAGTTTCTCAAATTCCACATGCGTATACACGAGAAGCGCGGTTCAAAGAGCATTCAAGATGCATTGCCCGTAGGTGCCCACCAACAATACAGCGAACTGAATCAGTTCTACTGCGAGATCTGCAACAAGAGCTTCGACGAAAACCTACTGACAGTGCACAAGCAGATGCACCAGAAAACGGTCTATGAAATCAGTTGCAAAATCTGTAACCGCAAGTTTGAGGATCCTATTACCTACCAGATGCACCTGAAGATTCACGAGAAACCACGCACCGTCGATAGTGTTAAAAAGACTACGGCTCGCTCTAATGTCAGCGGCGGCGACAAGGAGAGAGGCTTTCCGTGCCAGTTCTGTGATAGAGTGTTTGGCCGTCCATATGAGAAAGTCAAGCACGAGCGGGTGCACACAGGCGAGAAGCCCTACTCCTGCGAGGTGTGCGGAAAAACTTTTCGCGTGTCCTACTCGCTCACTCTGCACCTGCGTACGCACACGGATATTCGGCCCTATGTCTGTACTGTTTGCAACAAACGCTTCAAGTCCCACCAAGTGTATTCACATCACCTGCGGATTCATAGTTCTGAGCGCGAATTCGCCTGCGACGTGTGCTCAAAGACCTTTCGTACCTCAGTGCAGCTCTACTCGCACAAAAATTCACACACCAAGCCGTACCAGTGCGCTGTGTGCAATCGACCCTTTTCCTCGATGTACGCCGTCAAGGGCCATATGCAAACCCACCAAGAGGAAAGCAACAAGCCTTCGGCAACTAAGGGTACGACCTCCGGCAAGAGCGTGCCAGTGGCAAAGTTCTGGTGTAAGGTATGTGGAGCTGAATACGCGCGACTCTTTGCCCTGCGCCTGCACATGAAATCGGCCCATGGCGTAACAGAGGACGCAGATGGGCAGCGGGAAGAAGTACGTGAGGCTGAAGAGGCGCACACTGCCGAGTCTGAGGATTCGGAAACGGCTGTGCTGATTGCAGCCGCAGAAGCGGATGCCGCGTATATTAGTGCTGTGGTAAACGATGTGGACTTAGCTGGCTCCGTTCCGACTTACCAGGAGGGTGTTGAGTTTGACGTGGACAACTTCCATAGTGAGGAAATCATAACGGATTGGCTCAAGTAG
Protein Sequence: MSSPRGCEDAAMSPSMHVEHAVSTESATQELFFYCELCGRVYEDSEAFNRDHTPQSSCCAVVKEDVDFVEDPTVEEETEEIVEADVPLWEVVDVPETSAMTEQNETDPSHSERYFCYDCHSIFENRSSAEDHVCPGAELAHSTSIESNVASSPKTSIRRKVPTTNAKTGSKAVSSISCDICKTVFSSSKFLKFHMRIHEKRGSKSIQDALPVGAHQQYSELNQFYCEICNKSFDENLLTVHKQMHQKTVYEISCKICNRKFEDPITYQMHLKIHEKPRTVDSVKKTTARSNVSGGDKERGFPCQFCDRVFGRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTDIRPYVCTVCNKRFKSHQVYSHHLRIHSSEREFACDVCSKTFRTSVQLYSHKNSHTKPYQCAVCNRPFSSMYAVKGHMQTHQEESNKPSATKGTTSGKSVPVAKFWCKVCGAEYARLFALRLHMKSAHGVTEDADGQREEVREAEEAHTAESEDSETAVLIAAAEADAAYISAVVNDVDLAGSVPTYQEGVEFDVDNFHSEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00546114; iTF_00504138; iTF_00615057;
90% Identity: -
80% Identity: -