Basic Information

Insect: Drosophila vallismaia
Gene Symbol: zfh1
Assembly: GCA_035047325.1
Location: JAWNPU010000073.1:7949071-7968902[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0018 0.15 12.7 1.6 2 23 73 95 72 95 0.95

2 9 0.015 1.3 9.7 0.1 1 23 307 329 307 329 0.96

3 9 9.6e-05 0.0084 16.7 1.7 2 23 343 364 342 364 0.97

4 9 4.7e-06 0.00041 20.8 6.3 1 23 373 395 373 395 0.99

5 9 0.00028 0.024 15.2 1.2 3 21 403 421 401 422 0.94

6 9 0.0065 0.56 10.9 0.7 2 21 652 671 651 672 0.92

7 9 9.2e-06 0.0008 19.9 0.5 1 23 991 1013 991 1013 0.95

8 9 4.7e-05 0.004 17.7 7.4 1 23 1019 1041 1019 1041 0.98

9 9 0.0023 0.2 12.3 4.3 1 21 1047 1067 1047 1068 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0018	0.15	12.7	1.6	2	23	73	95	72	95	0.95
2	9	0.015	1.3	9.7	0.1	1	23	307	329	307	329	0.96
3	9	9.6e-05	0.0084	16.7	1.7	2	23	343	364	342	364	0.97
4	9	4.7e-06	0.00041	20.8	6.3	1	23	373	395	373	395	0.99
5	9	0.00028	0.024	15.2	1.2	3	21	403	421	401	422	0.94
6	9	0.0065	0.56	10.9	0.7	2	21	652	671	651	672	0.92
7	9	9.2e-06	0.0008	19.9	0.5	1	23	991	1013	991	1013	0.95
8	9	4.7e-05	0.004	17.7	7.4	1	23	1019	1041	1019	1041	0.98
9	9	0.0023	0.2	12.3	4.3	1	21	1047	1067	1047	1068	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCGTCGTCTTCACGTTTCGGCCAAAAGGATACCATCATTCAGCAGAGCATGCCATCCACAGCCTTCACCATGCAGTTTCCCTCGCTGGCCTCCAGTCTGCACCACCATAACCATAACCAGTCGCCGCACCACAGCAAGCCCGGACCCCAGGATGGCCAGCACGTGCAACCAGGTGCCGCCGCCGACGATTTTCTGGTCAAGTGCACCCAGTGCCACCAGCGCTTCACGGACTTCCAGTCCCTTAGCGAACACATTGCCAGCGAGCATCCCCACGACAAGCTGAATCTGGGAGCCGCGCAGCCGGAGAGCGAGCCGGAGGACGAGCAGAGCAACCTGAGCAGCGGCAGTAGGCGGTACTTGAAGTCGCCGGAGAACACGAATGCCAACGGGGGCAGCGGTATTGCCAACtccagcaataacaacaacaacaacaacagtgatctggccaaaaaccacaacaacaccaacaagcTGTCGCCCATGAGCTCGCCCATTTCCGGTGTAGGAATGGGCGGAGTGGGATCGGGTCCACCCAGCGATCTGTTTGCCCACCTCTCCCACGGCACGCCCCAGCTGCCCGGCCAGCTGCCCGCCCACCTGCAAGCACAGTTCATGGCCGCCGCCGCCCTGGCCATGCAATCCGCCCGCTCCGCCAGCTCCAGCTCCCCCAGCAGCCTCCACCAGTCGCAGCAgacccagcagcagcagcagcaatcctCGCAACTGCAACTCCAGCAataccaccaccagcagcaacagcaacaccaaccaCCCCTGCTGCCGCCCCAGCTACCGGGGAGCAACAGCAGCGTGGGCAGCAACTCCGCCTACGACCTGGATCTGAGTGCTCCGCGGTCAACCTCCAGCCCCGGCTCCACCACCGGGGATCTCAGCGGTGCCTATCCCTGCATGCAGTGCACCGCCGCCTTTGGTTCCAGGGAGCAGCTGGAGCAGCACGAGCTCCTCCACTCGCCCTGCGGCCAGCCAGCGACGCAGAATGTCTCACAGACCTGCCGCATCTGCCACAAGGCCTTCGCCAATGTCTACCGTCTCCAGAGGCACATGATCAGCCACGATGAGAGCGCCCTGCTGAGGAAATTCAAGTGCAAGGAGTGCGACAAGGCGTTCAAGTTCAAGCATCACCTCAAGGAGCACGTGAGGATCCATTCCGGCGAAAAGCCGTTCGGGTGTGACAACTGCGGCAAGAGGTTCTCCCATTCCGGCAGCTTCTCCTCCCACATGACCTCTAAGAAGTGCATCAGCATGGGCCTCAAGCTGAACAACAACCGGGCGCTGCTGAAGAGATTGGAGAAGCGACCGGGATCGGGTGCCTCGGCACGTCTCTCGCCTTCGGACCAGGCCAAGGGAAAGCTCCAGGAGCAGCAGGCATTGCCGGGTCTGCCGAATCCCATGATTTACTTTGCCAGCGATGCCCAGAACCAGGCTGGGAACAGTGGTCCGGCGTCGTTTCCCAATTTCCATCCCACGAACTACATGAATGCCGCCCTGCTGGCCTTTCCCAATCCCTTCATGGCAGCTGCCGCCCTGGATCCTCGCATGCATCCCTACAGCATACAGCGATTGCTGCAACTGACGGCTGCCGGTCAGCAACAGAGGGAGGAGGAGCAGCGGGAGCAGGAGAaccaggaggagcaggagaaccaggaggagcaggaggaggagacACCCGAGGAACCCAAACTGGTGATGGATATCGATGTTCCGGAGATCAAGGAACGGGCTGTCACCCCTCCGATCCACGAGGAAGCCGCTCCCATCAAGCAGGAAGCCAGTCGCGAAGCTTCTCCGGCTCCGGAAAGCTCTCCACCATCGCCCCAGGTCGTCAAGCAGGAAGTGGAGGCGCCACCGCAAGAACCAGAGCCTGAGATCATGGACGAAGAACCCATTCCAGCTCCCGAGCAGCCTGCCGACTTGCGCTGCAGTCGCTGCTCCAAGCAGTTCAACCATCCCACGGAACTGGTCCAGCACGAGAAGGTCCTTTGCGGTCTAATCAAGGAAGAAATGGAGCAGCActtccagcagcagcaacagcagcagcagcagagcctGCAACCCCCAGCCTTTGTCCTGCCGTCCGCCAGCGAGGAAGACGATGaagaggacgaggaggaggagcccAGGAACCAGGAGACTGGCGAACGGAAAGTCCGCGTCCGAACCGCCATCAACgaggaacagcagcagcaactgaaGCAACATTATTCTTCCAACTCCCGACCCAGCAGGGATGAGTTCCGCTTAATAGCCGCCAGGTTGCAGCTGGATCCGCGGGTCGTCCAGGTCTGGTTCCAGAACAATCGCTCGCGGGAGCGCAAGATGCAGAGTTTCCAGAGCAACCAAAGTGCCACGGCCCCTGCCGCAAACGAATCCCAAGGAAATGTGGATCAGCCTCTGGATCTGTCCATTAAGCGGGATCCTCTGACCCCGAAGAGTGAGAGTTCACCCTCGTACATGCCTCCCCAGACGGGCGAAGGACTCAATCCGGAAGCCATCAATCTGAGCCGGAAGTTCTCCAGCTCAGCTTCGATGTCCCCGGCTTCGATTTCTCCCTCATCCGCGGCAGCTTTGTATTTCGGAGCTGCCCCGCCGCCATCACCGCCCAACAACCAACTGGAGGCGAACCCTTCCCGCAGCGGGCAAGCCTTCCCGGGACTGCCCTACATGCTGCCCATGCAGCGACTGCCCATGGAGGCGCTCTTTCAGATGCGACCAGGTGGAGAGTACGCCCCAAACCATCCCCTGATGAACAGTATTAAGCTGCCCGACTACCGAGGCACCAGCCTAAGCCCGGGCGGATCGGAGAAGCGCTCCTGGCGCGACGATGACTCGCGCATCTCGCACGAGGATGACTTCTCCGGCGGCCTGCTGCCCCCCAAGCCGAGGCGCGGCAAGGCGGAGACCCATGGACACGCCGGCGATCCGGACTTGCCTTACGTCTGCGATCAATGCGACAAGGCCTTCGCCAAGCAGAGCTCCCTGGCCCGGCACAAGTACGAGCATTCCGGTCAACGACCCTACCAGTGCATGGACTGCCCCAAGGCCTTCAAGCACAAGCACCATCTGACGGAGCACAAGCGCCTGCATAGCGGGGAGAAGCCCTTTCAGTGCTCCAAGTGCCTGAAACGCTTCTCGCACTCGGGCAGCTACAGCCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSSRFGQKDTIIQQSMPSTAFTMQFPSLASSLHHHNHNQSPHHSKPGPQDGQHVQPGAAADDFLVKCTQCHQRFTDFQSLSEHIASEHPHDKLNLGAAQPESEPEDEQSNLSSGSRRYLKSPENTNANGGSGIANSSNNNNNNNSDLAKNHNNTNKLSPMSSPISGVGMGGVGSGPPSDLFAHLSHGTPQLPGQLPAHLQAQFMAAAALAMQSARSASSSSPSSLHQSQQTQQQQQQSSQLQLQQYHHQQQQQHQPPLLPPQLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTAAFGSREQLEQHELLHSPCGQPATQNVSQTCRICHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKRPGSGASARLSPSDQAKGKLQEQQALPGLPNPMIYFASDAQNQAGNSGPASFPNFHPTNYMNAALLAFPNPFMAAAALDPRMHPYSIQRLLQLTAAGQQQREEEQREQENQEEQENQEEQEEETPEEPKLVMDIDVPEIKERAVTPPIHEEAAPIKQEASREASPAPESSPPSPQVVKQEVEAPPQEPEPEIMDEEPIPAPEQPADLRCSRCSKQFNHPTELVQHEKVLCGLIKEEMEQHFQQQQQQQQQSLQPPAFVLPSASEEDDEEDEEEEPRNQETGERKVRVRTAINEEQQQQLKQHYSSNSRPSRDEFRLIAARLQLDPRVVQVWFQNNRSRERKMQSFQSNQSATAPAANESQGNVDQPLDLSIKRDPLTPKSESSPSYMPPQTGEGLNPEAINLSRKFSSSASMSPASISPSSAAALYFGAAPPPSPPNNQLEANPSRSGQAFPGLPYMLPMQRLPMEALFQMRPGGEYAPNHPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDFSGGLLPPKPRRGKAETHGHAGDPDLPYVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615732;
90% Identity: iTF_00550414;
80% Identity: iTF_00614808;