Basic Information

Insect: Drosophila vallismaia
Gene Symbol: Kr-h1
Assembly: GCA_035047325.1
Location: JAWNPU010000090.1:11585528-11590330[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0039 0.34 11.6 3.0 1 23 225 247 225 247 0.98

2 8 1.7e-06 0.00015 22.2 0.5 1 23 301 323 301 323 0.99

3 8 2e-05 0.0018 18.8 2.3 1 23 329 351 329 351 0.98

4 8 4.2e-07 3.6e-05 24.1 2.8 1 23 357 379 357 379 0.99

5 8 3.2e-07 2.8e-05 24.5 1.3 1 23 385 407 385 407 0.98

6 8 0.00011 0.0096 16.5 1.4 1 23 413 437 413 437 0.99

7 8 0.57 50 4.8 3.7 1 23 443 465 443 465 0.94

8 8 8.8e-07 7.6e-05 23.1 0.6 1 23 471 493 471 493 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0039	0.34	11.6	3.0	1	23	225	247	225	247	0.98
2	8	1.7e-06	0.00015	22.2	0.5	1	23	301	323	301	323	0.99
3	8	2e-05	0.0018	18.8	2.3	1	23	329	351	329	351	0.98
4	8	4.2e-07	3.6e-05	24.1	2.8	1	23	357	379	357	379	0.99
5	8	3.2e-07	2.8e-05	24.5	1.3	1	23	385	407	385	407	0.98
6	8	0.00011	0.0096	16.5	1.4	1	23	413	437	413	437	0.99
7	8	0.57	50	4.8	3.7	1	23	443	465	443	465	0.94
8	8	8.8e-07	7.6e-05	23.1	0.6	1	23	471	493	471	493	0.98

Sequence Information

Coding Sequence: ATGACCGATTTCTCGATGAACGATATTCTGAGATCATTTAGGAAAATGCGCATGAACAAGGGAGCGGGTCAAGGCGGTCACCATCAACAGCATCATCAGAATAATTATCGCCATCAGCCGCCGCAGCACGTTCAAGTCTACCAACCCACTTATCCCATTCAACAGTCCAAAGATTTGaagaaaattattaaaattattaagaaAAACTTGATCAAGGAGAAAATCACGCATTCAACAACCGCATCCAAAATGGTTTACTATCCCGCTAACCAGCTGCTTATAAAAACGGAGCAACCCAGTCAGGCGCAGTTCTGCCTGCAGGTTCAGCCCGCGCTGACAGCGACAACGACGTCCTCGAACTCGGGTCTGAGAGTCCTTGCCTCCGGCGGCCAGGAGCACTATGAGCTCCTGCAGACACCGCAGCAGCGACAGTTGcaactccagcagcagcagcagcacctccaggagcagcagcagttcgAAAGCTACCAGAGAGCtatccagcagcagcagcagcagcagcagcagatagTTTCCACCTCGACGCCAGGAGTCAACAGGATCAAGACAGAGGTGTCCGTAAACTTTGTCCCAGCAGCGGcacaaccccaaccccaaccccaagcGCAGGCGCAGCCGCAGCCACGCAAGTCCGGAGTCAACAAGCCGCAGTTCAAGTGCGAACAGTGTGGCATGACCTTCGGGAGCAAGTCGGCCCACACCTCCCACACCAAGTCGCATGCCAAGAACGCAGAGCTCTCCATGGTAGAAGGAGGCGGCAATCCTTCTGCCGCCACGTTACCGCCCGCCATCGAGCTGAACGAGGCGGGTCTCCCGGTGGGCATCCCCAAGAGCCCAACCATCAAGCCGCTGGCCAATGTGGCTGCCGGAGCCGATCCCTATCAGTGCAATGTGTGCCAGAAGACCTTTGCCGTTCCTGCCAGGCTGATCCGTCATTACCGAACCCATACCGGAGAGCGACCCTTCGAGTGCGAGTTCTGCCACAAACTGTTCAGCGTCAAGGAGAACCTGCAGGTCCATCGGCGCATCCATACCAAGGAGCGTCCCTACAAGTGCGAGGTATGCGGCCGGGCCTTTGAGCACTCCGGCAAGCTGCATCGCCATATGCGCATCCATACCGGCGAGCGACCGCACAAGTGCTCCGTCTGCGAGAAGACCTTCATCCAGTCGGGCCAGTTGGTCATCCACATGCGCACCCACACCGGCGAAAAGCCGTACAAGTGCCCGGAGCCGGGCTGCGGCAAGGGATTCACCTGCTCCAAACAGCTGAAGGTGCACTCGCGCACCCATACGGGCGAGAAGCCCTACCACTGCGACATCTGCTTCCGCGACTTTGGCTACAACCACGTCCTGAAGCTGCACCGGGTCCAGCACTACGGATCCAAGTGCTACAAGTGCACCATCTGCGACGAGACGTTCAAGAACAAGAAGGAGATGGAGGCCCACATCAAGGGCCATGCCAATGAGATTCCCGACGATGAGGCGGAGGCAGCAGCGGCCGGTACAggcacctcctcctcctccgtgGTGTCACCATCCTCGCACGGCGTCAGCAGCGAAGTCTCCgagagcagcagcaactcGCCGCCCAGCTCTCCGGCAGCCACCAAGAAGCCTCGCCAGTCACGTCAGCCCCGCGGAGCCAAGGCAGCCCCAgcctccgtctccgtctcggCCTCGGCTTCGGCCTCTCCATTCTCTCCCAGTTCTCCCAGCTCCACGTACTCGCCCTCGACGAGCAGCCTGGCCTCGCCGCCGCCCACCTCGGCCCACTATCTGCCCGCCCAGGTGGAGCAGGATGCCCTGAGCCGGGACAGCGGCGTCTCCAGCGCCCAGCTAGCCCACAGCAACTATACGGACGAGGAGCTGCCCACTGACCTCAGCATACAGCAGGTGGCGGGTGGTCAGCTGCCCACCCCGCCTGTCACCTACTACCAGGCCCAACCCAGTCTAGTGGAGCTGCAGCCCCAGGCCGCCGGACTCACCATCAATCCGGCCCTGCTCGAGGCCGCCAGCATGGCACGCCGTCACCACGACATCGACGAGCAAGTGCCGGAACGTGATCAGGACGAGGATGTGCATGCCGCCGCCTTGCAAATGATCCAACTGCGTCGTGGTCATGCCGCCACACCCCCTCCAGAGCAGCAGATGCAATACCAGCCGCCTccccagcagcaacagcagcagcagctgcacgTCAGCGATCTGGCGGCCAACTATGATGACACCCACGAAGCGACAGTTCTCATCGAGCACTTCAAGCGCGGAGATCTGGCCCGCCATGGACTCCACAAGGGTTACGCCCCAGTGCCCAAGTACGAATCCGCCTTGCCTAATCCGGATATCGTGCGTCGCGTGGAGGCCGCcatcggtctgagatcgagcACTGAGTCCCCTGAGCGGAGTTCCTCGCCGGAAAGCGACTCCCTGCTGATGGCCGACCGGAATGTGATGACCCTCCCGCTGCGCAAACGCAAACACTACATGAACAAGGGCGACGGCGGCCACGGGGAGTTGGAGAAGACCCAGGGGGCAGGCGGAGATGCAaactctgctgctgctggcgctgACCATCCAACGATGGATACCTTGGATAGTTCCGGGTCGAAGGTGATGCGGATGAGCTCGGTCATCCAGTTCGCCAAGGCCTCGTAG
Protein Sequence: MTDFSMNDILRSFRKMRMNKGAGQGGHHQQHHQNNYRHQPPQHVQVYQPTYPIQQSKDLKKIIKIIKKNLIKEKITHSTTASKMVYYPANQLLIKTEQPSQAQFCLQVQPALTATTTSSNSGLRVLASGGQEHYELLQTPQQRQLQLQQQQQHLQEQQQFESYQRAIQQQQQQQQQIVSTSTPGVNRIKTEVSVNFVPAAAQPQPQPQAQAQPQPRKSGVNKPQFKCEQCGMTFGSKSAHTSHTKSHAKNAELSMVEGGGNPSAATLPPAIELNEAGLPVGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCEVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKNKKEMEAHIKGHANEIPDDEAEAAAAGTGTSSSSVVSPSSHGVSSEVSESSSNSPPSSPAATKKPRQSRQPRGAKAAPASVSVSASASASPFSPSSPSSTYSPSTSSLASPPPTSAHYLPAQVEQDALSRDSGVSSAQLAHSNYTDEELPTDLSIQQVAGGQLPTPPVTYYQAQPSLVELQPQAAGLTINPALLEAASMARRHHDIDEQVPERDQDEDVHAAALQMIQLRRGHAATPPPEQQMQYQPPPQQQQQQQLHVSDLAANYDDTHEATVLIEHFKRGDLARHGLHKGYAPVPKYESALPNPDIVRRVEAAIGLRSSTESPERSSSPESDSLLMADRNVMTLPLRKRKHYMNKGDGGHGELEKTQGAGGDANSAAAGADHPTMDTLDSSGSKVMRMSSVIQFAKAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481689;
90% Identity: iTF_00546117;
80% Identity: -