Basic Information

Insect: Drosophila merina
Gene Symbol: Kr-h1
Assembly: GCA_035047645.1
Location: JAWNPH010000055.1:11630368-11634517[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0038 0.34 11.7 3.0 1 23 220 242 220 242 0.98

2 8 1.6e-06 0.00015 22.3 0.5 1 23 295 317 295 317 0.99

3 8 1.9e-05 0.0018 18.9 2.3 1 23 323 345 323 345 0.98

4 8 4e-07 3.6e-05 24.2 2.8 1 23 351 373 351 373 0.99

5 8 3.1e-07 2.8e-05 24.5 1.3 1 23 379 401 379 401 0.98

6 8 0.00011 0.0097 16.5 1.4 1 23 407 431 407 431 0.99

7 8 0.55 50 4.8 3.7 1 23 437 459 437 459 0.94

8 8 8.4e-07 7.7e-05 23.1 0.6 1 23 465 487 465 487 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0038	0.34	11.7	3.0	1	23	220	242	220	242	0.98
2	8	1.6e-06	0.00015	22.3	0.5	1	23	295	317	295	317	0.99
3	8	1.9e-05	0.0018	18.9	2.3	1	23	323	345	323	345	0.98
4	8	4e-07	3.6e-05	24.2	2.8	1	23	351	373	351	373	0.99
5	8	3.1e-07	2.8e-05	24.5	1.3	1	23	379	401	379	401	0.98
6	8	0.00011	0.0097	16.5	1.4	1	23	407	431	407	431	0.99
7	8	0.55	50	4.8	3.7	1	23	437	459	437	459	0.94
8	8	8.4e-07	7.7e-05	23.1	0.6	1	23	465	487	465	487	0.98

Sequence Information

Coding Sequence: ATGACTGATTTCTCGATGAACGATATTCTGAGATCATTTAGGAAAATGCGCATGAACAAGGGAGCGGGTCAAGGCGGTCACCATCAGCATCATCAGAATAACTATCGCCATCAGCCGCCGCAGCACGTTCAAGTCTACCAACCCACTTATCCCATTCAACAGTccaaagatttgaagaaaatcattaaaattattaaaaaaaatctgatCAAGGAGAAAATCACGCATTCAACCGCATCCAAAATGGTTTACTATCCCGCTAACCAGCTGCTTATAAAAACGGAGCAACCCAGTCAGGCGCAGTTCTGCCTGCAGGTTCAGCCCACGCTGACGGCCACGACGACCTCGAACTCGGGTCTGAGGGTCCTCTCCTCCGGCGGTCAGGAGCACTATGAGCTCCTGCAGACGCCGCAGCAGCGACAGTTGcaactccagcagcagcagcagcacctccaggagcagcagcagttcgACAACTACCAGAGAGCtatccagcagcagcagcagatagTTTCCACCTCGACTTCGCCAGTCAACAGGATCAAGACAGAGGTGTCCGTGAACTTTGTCCCAGCAGCGGCACAACCCCAGCTCCAGTCCCAACCCCAAACCCAAGCGCAGGCGCAGCCCCGCAAGTCCGGCGTCAACAAGCCGCAGTTCAAGTGCGAACAGTGTGGCATGACCTTTGGCAGCAAGTCGGCCCACACCTCCCACACCAAGTCGCATGCCAAGAACGCAGAGCTGTCCATGGGAGAAGGAGGCAATCCTTCCGCTGTCACGTTACCGCCTGCCATCGAGCTGAACGAGGCGGGTCTCCCGGTGGGCATCCCCAAGAGCCCCACCATCAAGCCGCTGGCCAATGTGGCCGCCGGAGCCGATCCCTATCAGTGCAATGTGTGCCAGAAGACCTTTGCCGTTCCCGCCAGGCTGATCCGTCACTACCGAACCCATACCGGAGAGCGACCCTTCGAGTGCGAGTTCTGCCACAAACTGTTCAGCGTCAAGGAGAACCTGCAGGTCCATCGGCGCATCCACACCAAGGAGCGTCCCTACAAGTGCGAGGTATGCGGTCGGGCCTTCGAGCACTCCGGCAAGCTGCACCGTCACATGCGCATCCACACCGGCGAGCGACCGCACAAGTGCTCCGTCTGCGAGAAGACATTCATCCAGTCCGGACAACTGGTCATCCACATGCGCACCCACACCGGCGAGAAGCCGTACAAGTGCCCGGAGCCGGGATGCGGCAAGGGATTCACCTGCTCCAAACAGCTGAAGGTGCACTCGCGCACCCATACGGGCGAGAAGCCCTACCACTGCGACATCTGCTTCCGCGACTTTGGCTACAACCACGTCCTGAAGCTGCACCGGGTCCAGCACTACGGCTCCAAGTGCTACAAGTGCACCATCTGCGACGAGACGTTCAAGAACAAGAAGGAGATGGAGGCCCACATCAAGGGCCATGCCAATGAGATTCCCGACGACGAAGCCgaggcggcagcagcaggcacctcctcctcctccgtgGTGTCGCCATCCTCGCACGGCGTTAGCAGCGGAGTCTCcgagagcagcagcaactcgCCGCCCAGCTCTCCGGCAGCCACCAAGAAGCCTCGCCAGCCACGTCAGCCCCGCGGAGCCAAAGCAGCGGCAGCCTCCGTCTCCGCCTCAGCTTCGGCCTCTCCATTCTCTCCCAGCTCGCCCAGCTCCACGTACTCGCCCTCGACCAGCAGCCTGGCCTCGCCTCCGCCCACCCAGGTGGAGCAGGATGCCCTGAGCCGGGACAGCGGCGTCTCCAGCGCCCAGCTAGCCCACAGCAACTATGCGGACGAGGAGCTGCCCACTGACCTCAGCATACAGCAGGTAGCGGCGGGTGGTCAGCTGCCCATCCCGGCTGTCACCTACTACCAGGCCCCGCCCAGTCTACTGGAGCTGCAGCCCCAGCCCGCCGGACTCACCATCAATCCGGCCCTGCTCGAGGCGGCCAGCATGGCACGCCGTCACCACGACATCGACGAGCAAGTGCCGGAACGCGACCAGGACGAGGATGTGCATGCCGCCGCCTTGCAAATGATTCAACTGCGTCGTGGTCATGCAGCCACACCCCCTCCAGAGCAGCAGATGCAATACCAGCCGCctctccagcagcagcaacagcagctgcaCGTCAGCGATCTGGCAGCCAACTATGATGACACCCACGAGGCGACAGTTCTCATCGAGCACTTCAAGCGCGGAGACCTAGCCCGCCATGGACTCCACAAGGGTTACGCCCCAGTGCCCAAGTACGAATCCGCCTTGCCTAATCCGGATATCGTGCGTCGCGTGGAAGCCGCCATCGGACTGCGGTCCAGCACTGAGTCTCCTGAGCGGAGTTCCTCCCCGGAAAGCGACTCCCTGCTGATGGCCGACCGGAATGTGATGACCCTCCCGCTGCGCAAACGCAAACACTACATGAACAAGGGCGACAGCGGCCACGGGGAGTTGGAGAAGCCCCAGAGCGCTGGCGGAGAAGCAAACTCTGCAGCTGCTGGCGCTGACCATCCAGCGATGGATACCTTGGATAGTTCCGGGTCGAAGGTGATGCGGATGAGCTCGGTCATCCAGTTCGCCAAGGCCTCGTAG
Protein Sequence: MTDFSMNDILRSFRKMRMNKGAGQGGHHQHHQNNYRHQPPQHVQVYQPTYPIQQSKDLKKIIKIIKKNLIKEKITHSTASKMVYYPANQLLIKTEQPSQAQFCLQVQPTLTATTTSNSGLRVLSSGGQEHYELLQTPQQRQLQLQQQQQHLQEQQQFDNYQRAIQQQQQIVSTSTSPVNRIKTEVSVNFVPAAAQPQLQSQPQTQAQAQPRKSGVNKPQFKCEQCGMTFGSKSAHTSHTKSHAKNAELSMGEGGNPSAVTLPPAIELNEAGLPVGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCEVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKNKKEMEAHIKGHANEIPDDEAEAAAAGTSSSSVVSPSSHGVSSGVSESSSNSPPSSPAATKKPRQPRQPRGAKAAAASVSASASASPFSPSSPSSTYSPSTSSLASPPPTQVEQDALSRDSGVSSAQLAHSNYADEELPTDLSIQQVAAGGQLPIPAVTYYQAPPSLLELQPQPAGLTINPALLEAASMARRHHDIDEQVPERDQDEDVHAAALQMIQLRRGHAATPPPEQQMQYQPPLQQQQQQLHVSDLAANYDDTHEATVLIEHFKRGDLARHGLHKGYAPVPKYESALPNPDIVRRVEAAIGLRSSTESPERSSSPESDSLLMADRNVMTLPLRKRKHYMNKGDSGHGELEKPQSAGGEANSAAAGADHPAMDTLDSSGSKVMRMSSVIQFAKAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481689;
90% Identity: iTF_00504140; iTF_00615053;
80% Identity: -