Basic Information

Insect: Drosophila vallismaia
Gene Symbol: zfh1
Assembly: GCA_035047325.1
Location: JAWNPU010000045.1:63393-67527[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.5e-05 0.0022 18.5 1.1 1 23 155 177 155 177 0.97

2 15 0.0018 0.16 12.7 1.2 3 23 185 205 183 205 0.94

3 15 0.00025 0.022 15.4 0.2 1 23 358 380 358 380 0.98

4 15 0.00055 0.048 14.3 1.8 1 23 386 408 386 408 0.98

5 15 3.4e-05 0.003 18.1 1.6 1 23 439 461 439 461 0.97

6 15 0.0095 0.82 10.4 2.7 3 23 494 514 493 514 0.95

7 15 0.093 8.1 7.3 1.2 1 23 520 543 520 543 0.94

8 15 0.024 2.1 9.1 0.4 3 19 552 568 551 569 0.95

9 15 0.00014 0.012 16.1 5.6 1 23 578 600 578 600 0.97

10 15 0.043 3.7 8.4 0.4 2 23 606 627 605 627 0.96

11 15 8.4e-06 0.00073 20.0 1.0 1 23 636 658 636 658 0.98

12 15 0.0042 0.37 11.5 0.2 3 23 666 686 664 686 0.97

13 15 5.1e-05 0.0044 17.6 0.5 1 23 692 714 692 715 0.95

14 15 0.0012 0.11 13.2 0.5 1 23 725 747 725 747 0.97

15 15 0.0049 0.43 11.3 0.3 1 23 1271 1293 1271 1293 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.5e-05	0.0022	18.5	1.1	1	23	155	177	155	177	0.97
2	15	0.0018	0.16	12.7	1.2	3	23	185	205	183	205	0.94
3	15	0.00025	0.022	15.4	0.2	1	23	358	380	358	380	0.98
4	15	0.00055	0.048	14.3	1.8	1	23	386	408	386	408	0.98
5	15	3.4e-05	0.003	18.1	1.6	1	23	439	461	439	461	0.97
6	15	0.0095	0.82	10.4	2.7	3	23	494	514	493	514	0.95
7	15	0.093	8.1	7.3	1.2	1	23	520	543	520	543	0.94
8	15	0.024	2.1	9.1	0.4	3	19	552	568	551	569	0.95
9	15	0.00014	0.012	16.1	5.6	1	23	578	600	578	600	0.97
10	15	0.043	3.7	8.4	0.4	2	23	606	627	605	627	0.96
11	15	8.4e-06	0.00073	20.0	1.0	1	23	636	658	636	658	0.98
12	15	0.0042	0.37	11.5	0.2	3	23	666	686	664	686	0.97
13	15	5.1e-05	0.0044	17.6	0.5	1	23	692	714	692	715	0.95
14	15	0.0012	0.11	13.2	0.5	1	23	725	747	725	747	0.97
15	15	0.0049	0.43	11.3	0.3	1	23	1271	1293	1271	1293	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGAGCTATGGCGGCATCAAGTGGATTCCGCACCCCACCGCGCCGGACTTTTGCGAAGTAGAAATCCTAGAAAACGATGGTGGGAATGCAGTTCAGCAGGCGACGTCGGCATTTGTCGCTGGTGAGGGGGAGGCCGAGGAGGACTTGGACCATATGGCTGCCGAGAACCTTATTTTCATGGCTCGTGACGGTCAGCTAAGCGAGATCATAGCCGCCAACGAGGTATGCGGGGCTGGTGGGGCCGTCCTGGTCACAGCTGATGGCACCACCGTTGCCTACGCAGGGTCTTTCGACGATGACGCGCAAGTGGTCACCGAGGAGGTCATCACCGACGACTGGGTGCAGCACCAGGGGGCCGAGCGAGTGGAAATCGCCGCAGAGCAGATAGCAGACATAAGCAACTCACAGGAACTGCTGGATATGGAGCAGGACGAGTATACCGCCCTTCGACCATATCCTTGCGACTTCTGCAGCCGCCGCTTCAAAAAGAAGGCCAGCTTAAACAACCACATGTTGGCGCACCAGAACGACAGGCCACATCTTTGCAAGCTGTGTGGAGCCCGATTCACGCGCCGCCCTGAGCTAATTAGCCACTTTAAAGCCCACGCCGAGGCACAAGATGCAGCAGATGCTGAggcagcggcaacagcagccGCCGCTTCCTCCGCTTCCATTAAGTTTGAGTACCAGACTCAAGGCCAGTTGGATGACCATTTCTACGAGCAGGAGTGGTCCCTTAATCACCAGGATCACGATCACGATCACGATCAGGCTCATCACGAGCAGCACAATCAATCAGAGCAGCAGCTTAGCTCCTGCAATAATGAAGCTCTGGTGGATAGCTACCCTTCCGCTGTGGCGCCGTCAGTAACACCCGCGCGCGGCAGGATCAGCAGGCTAAAGCCGAAGGAGGAGAGTAGGCAGTTCATCGGGATGGCAGAAAAACAATCGACACCCTACTTGGACAGAGACAAGGGACAGTCAATGGTTACCACCTCGCAATCCGCGGCCTTTGACCCGCCGCCTCAGCCAAAATATCCCGTTTTGGACGATAAAAAGCCATTCGTGTGTCAGCAGTGCGGTCTGGCCTTTGCCCGAGAAAAAGCCCTTGTGTCGCATACGAAGAACCACCGCATGGACTCGCCGTTTGAGTGCAACCATTGCCAGGAGATGTTCTGGGACAATAACAGCCTGCAGGAGCACCTTAAAACTCACCAATTTGAGGAGAGCAATTCGGAGTACGATCCCGCTTCCGCGGAGGACTCTGCTAGTGAATCGGATCCGGAGGAGCAGCTGTACGGTGACTTTTACTGCGCCGAGtgtggcatttcgtttcatcGCCAGGATCTGTTGCGACGCCACGCGAAGCAACATTTGAAACAGCCCGACACATTGGCTGGAGAAAGCAATTCTGCCACCACTGCTGGCGGTGAAGTGGAAACTAAGGAGTCAAGCGGTGGATCTAACTGCTGTCACACATGCGGGAAGTGTTTTCCTAGTCCTCTGGAGATGCTCGCTCACGCTGAGATCCACTCCAGGTTTCCCCCCTTCAAATGCGTCCTATGTGGAATAAGCTTCTATGAAGAGTTGGAAATAAAGCGACACCTTCACAACCGCCACCCCAACGAGCTGAAGGCCAATTCGTGCGTCCTGTGCGGTAAGGAGTGCCGTGACCGAAAGGCCTTAATCAAGCACGCCTGGGACCATTCCCGCGAAAAGTGCCACTCTTGCTCCAAGTGCGGCAAGAACTTTCACAACAAAGCGCGCCTAAAGCGGCACATGGCCTCGCATCGCGACAAGTCGGTGGTGTGTGAGGTGTGCCAGGAAGAGTTTCCGGATGGGCGCACCCTTTCCAACCACCGCCACTCACATAGCACCACCTCGCCCGGTAAACTCTTCCCTTGTCACGAATGCGGCAAGACTTTTGGGTCACGCAGCTCCCAACAGATTCATGTGCGAATTCACACGGGAGAAAGACCCTATGGATGCCGGTTCTGCTGGAAGGCCTTCGCTGATGGAGGTACTCTGCGAAAGCATGAACGGATCCACACGGGCGAGAAGCCTTATGCTTGCTCGGTCTGTCCACGTGCCTTCAACCAACGGGTGGTACTGCGTGAGCACATTCGCTCCCACCACTCGGGTCTGGATGTGGCCCGCAACACTTACCACTGCACGGTATGCTCCGAGGATTTCCCCTCGTCTAACGACCTCATTCAGCACCTTATACAGCACAGCGACTCAAACACTGCCAAGCAGAGACAGCCAATCACCGGACCCCGCAAGTACAAGAGGCGCCGCAAGCTGCAGCCGCATGAAATCGTTCAAATGCGGGCGGAACACAAGGAAGACAATAGCGATGAAGAAGCCGTGGGCGAGGGGGATCGCGACCGCGGGGAAGACGATTACGCCAGCGACATTGACATCTGCGACATTAACGTTGACCAGGTAGACGATTTTTTCGACATAGCAGAGTCCCCTAAAAAAGAGAAGCGCAAAAGAACGTCGGCAAAAACAGCATCTAAACATAATGGTTCGAACGGAGGTACGGGAATGACTGGAGGAGATGGATCGGCAAAGCCGGTTCTGGCAAAGGAAAATACAAAACTGCGATACGATTCCACAAGCAGTCATCAGTCGGATCGCATCTGGGAAGAGAAGTTTCTGCAAGACAGTCAGGCTCCGCTTTTCCAGATTGATTCTTTGGTGGTGGTCAACGATACTACGCTTCCGCCCGCCAGTTCCAGTCAGTCAATGCTGCACAAAACTAGGGCTGCAGTCAAACAACTCTCCAGACCAGCAGAAGCTTTGGCCAGCACGGCTTCGACCACATATTCGTCATCTACATCTTCCAGTCGCAGTCGCAAAAAGGCAGGTTCCAAGACTAGCAACAAGGCTCCATCTGCCATCAGCAGTTCCTCCCGACCTCGTATGATTCACACGGAAAAGGCCAGGGCTACGAAATCGGTGGCAGGCAGTGAGTCCTCCTCCAAGAAAACTCGCTCAAAGGTGTACGTTACGCGCACTGAAACTACCAGCAATTTGGGCGCTCTAGAAAAATCGTGCATCGTGGACGACTATGAGATTATCTCACCAGCCACCCAGCCTCCCAATCAGATTAGTTCGAGTCCTTTGCATAttaagcaggagcaggaacacCAGCAGCATCGGGTCCAGTTGATGTACGATGACAACCTCCTGATAGACGCCGCTCTGCTGCGGGAAAAGACTTACGAAAAGTTCAACCCTAGCATCGTAAACGATCTGGAGGAGATCCTGCGGTCACCGCTAAAGCACGACCGAAACTCCCGTCTCCGCTTTACCAGCGAATCCTCGACTACGCCCCAATTCCTGCCAGAGGAGGAACAAAACCTGATAAAAATCGAGCCCACCTCGCCGGATTTGAGAGAAATGGTGGAGAGTCAGCAAAGAGTCACTTCATCGTCTTCATCCTCGTCAGCTAGAACCTCACGACACTTGCGTCAAATCACTACCAACAACGGACTGAGAGCGGGGAGCAAGCGGTCCGCAAACGGAAAGTCGTCCCCTGGCGAAGGACCTATGACCAAGAAGTTGACGTCCTCCGCCTCGGCTGTCAGCAAAGTAGGCGACTCCTCTTCCTCGTACCTTGGGTACGGGGTGGAAGCGTACAGCGTGAACCAATGCGTACCTGCCAACGGAAGCACTAACGACGTGGGCAGCGGTTTCTTCTCCATTTCGGAAGTGGTCTCCGCTGCCGATGCCGCGGATGCAGCGGCcaaggcggcggcggcggccggAAGATCGGAGCGAAAGACGCGCTACTTCGAGTGTGAGATGTGCACTGCTATCTTCTACGATCGGGCCCAGCTTCTGGATCACGTGCACATCCACATCTAG
Protein Sequence: MNNQSYGGIKWIPHPTAPDFCEVEILENDGGNAVQQATSAFVAGEGEAEEDLDHMAAENLIFMARDGQLSEIIAANEVCGAGGAVLVTADGTTVAYAGSFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIADISNSQELLDMEQDEYTALRPYPCDFCSRRFKKKASLNNHMLAHQNDRPHLCKLCGARFTRRPELISHFKAHAEAQDAADAEAAATAAAASSASIKFEYQTQGQLDDHFYEQEWSLNHQDHDHDHDQAHHEQHNQSEQQLSSCNNEALVDSYPSAVAPSVTPARGRISRLKPKEESRQFIGMAEKQSTPYLDRDKGQSMVTTSQSAAFDPPPQPKYPVLDDKKPFVCQQCGLAFAREKALVSHTKNHRMDSPFECNHCQEMFWDNNSLQEHLKTHQFEESNSEYDPASAEDSASESDPEEQLYGDFYCAECGISFHRQDLLRRHAKQHLKQPDTLAGESNSATTAGGEVETKESSGGSNCCHTCGKCFPSPLEMLAHAEIHSRFPPFKCVLCGISFYEELEIKRHLHNRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDFPSSNDLIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPHEIVQMRAEHKEDNSDEEAVGEGDRDRGEDDYASDIDICDINVDQVDDFFDIAESPKKEKRKRTSAKTASKHNGSNGGTGMTGGDGSAKPVLAKENTKLRYDSTSSHQSDRIWEEKFLQDSQAPLFQIDSLVVVNDTTLPPASSSQSMLHKTRAAVKQLSRPAEALASTASTTYSSSTSSSRSRKKAGSKTSNKAPSAISSSSRPRMIHTEKARATKSVAGSESSSKKTRSKVYVTRTETTSNLGALEKSCIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHRVQLMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHDRNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTSSSSSSSARTSRHLRQITTNNGLRAGSKRSANGKSSPGEGPMTKKLTSSASAVSKVGDSSSSYLGYGVEAYSVNQCVPANGSTNDVGSGFFSISEVVSAADAADAAAKAAAAAGRSERKTRYFECEMCTAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476060;
90% Identity: iTF_00546096; iTF_00504122;
80% Identity: -