Basic Information

Insect: Drosophila vallismaia
Gene Symbol: Zfx
Assembly: GCA_035047325.1
Location: JAWNPU010000001.1:5136835-5138826[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0015 0.13 13.0 5.8 1 23 167 189 167 189 0.94

2 15 2.1e-05 0.0018 18.8 4.5 1 23 195 217 195 217 0.98

3 15 3.2e-06 0.00028 21.3 1.8 1 23 235 257 235 257 0.98

4 15 0.00012 0.011 16.4 0.6 1 23 263 286 263 286 0.97

5 15 0.00041 0.036 14.7 3.7 1 23 297 319 297 319 0.98

6 15 0.0035 0.3 11.8 0.4 2 23 352 373 351 373 0.95

7 15 0.0062 0.54 11.0 0.3 1 20 377 396 377 398 0.93

8 15 0.00021 0.018 15.6 1.1 1 23 411 433 411 433 0.98

9 15 1.1e-05 0.00095 19.7 4.4 1 23 439 461 439 461 0.97

10 15 1.7e-05 0.0015 19.0 2.9 1 23 474 496 474 496 0.97

11 15 1.9e-06 0.00016 22.1 1.0 1 23 502 524 502 524 0.98

12 15 2.1e-06 0.00018 21.9 2.6 1 23 530 553 530 553 0.96

13 15 6.2e-07 5.4e-05 23.6 1.1 1 23 559 581 559 581 0.98

14 15 1.2e-05 0.001 19.6 0.4 1 23 587 609 587 609 0.98

15 15 0.25 22 5.9 6.7 1 23 622 644 622 644 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0015	0.13	13.0	5.8	1	23	167	189	167	189	0.94
2	15	2.1e-05	0.0018	18.8	4.5	1	23	195	217	195	217	0.98
3	15	3.2e-06	0.00028	21.3	1.8	1	23	235	257	235	257	0.98
4	15	0.00012	0.011	16.4	0.6	1	23	263	286	263	286	0.97
5	15	0.00041	0.036	14.7	3.7	1	23	297	319	297	319	0.98
6	15	0.0035	0.3	11.8	0.4	2	23	352	373	351	373	0.95
7	15	0.0062	0.54	11.0	0.3	1	20	377	396	377	398	0.93
8	15	0.00021	0.018	15.6	1.1	1	23	411	433	411	433	0.98
9	15	1.1e-05	0.00095	19.7	4.4	1	23	439	461	439	461	0.97
10	15	1.7e-05	0.0015	19.0	2.9	1	23	474	496	474	496	0.97
11	15	1.9e-06	0.00016	22.1	1.0	1	23	502	524	502	524	0.98
12	15	2.1e-06	0.00018	21.9	2.6	1	23	530	553	530	553	0.96
13	15	6.2e-07	5.4e-05	23.6	1.1	1	23	559	581	559	581	0.98
14	15	1.2e-05	0.001	19.6	0.4	1	23	587	609	587	609	0.98
15	15	0.25	22	5.9	6.7	1	23	622	644	622	644	0.98

Sequence Information

Coding Sequence: ATGGATTTTGTCATGCCAGATAGTCCGCCGGCGTTCGAAGAAGTGGCGGATCCCGCCGATCTAGAACCCCACTTGTTATTAACGGGAGGAGAGACCGCAGAGTTAAAGGAGTACATATGGGAGGAGGCGTTTCAACGGATGGAGGATGCTGAGGCGGAGCTTAGAGGAGAGTCCTCCTCGTCAGACGTCAGGAACAGCGACCAGATAAAAGTGCCCTTCAACAACACCATAAGCGTAAAGAACGAGCCCATTGATGAAGAGTTCCTGTGGGATCACAGTTCGAAAGAAGCACCCAGTCCAAGTGCATGCCCTCAAATCGATAGCTTTATAAAAGCAGAAGATCCAGAGTTTTATTTCGAAGAAGACTGGGAGCATGCCGAGTCGGATGAGGAAAGCGTGATAGAAGTGTTAAGTCATAGTAGCCGGCAGGAGGAGGATGGCGACGAAGAGGCATCTCAAGGCAGTTCGGAGCCCTCCCACAACGAAAACTCTTCCTTTTTTAAATGCGATCACTGTCCAAGAATCTTCAAATATGCGAAGAGTCTGAAGAATCACTGCATGAGCCACACCGGAGTCCTGCCCTACAATTGCAAGCACTGCAACCAGGCCTTCTCGCAAAAAGGGCGGTACAGAAAGCACATGATCACCCACGGAACGGATCCGAGTTCGGACTTGGAATATGATTCCGATGATGACAAGATGTTCAGATGCGCCCGTTGCCCCAAAAGCTTTAAGTTTGAGTCAAATCTTCGAAAACACGCCCGACTGCACACCGGAAACGTGCCCTTTCAATGCTCGCTATGCAAGGAGATCTTTAGCCAGAAAGCACGTTACGAGAAACACCTCCAGATTCCCCACAGTGCTGACGGTGCACCCATGGATCGGCCCTTTAAATGCACTCAGTGCGAGAAGCGGTTTAAGCTGGAACACGAATTTGACCGCCACATTCGCGGCCATAAACGTACGCAAAAAATGCTTGAAAAGTCAAAACCACCAGACAAACATGCAGATTCCATATACAAGGAAATCCAGGTTGATGGCACAATTATGTTAAAGTGCCCTGTTTGCGCCAACCTCTTCAAATCGCTACGGAACCTCACCAGGCACCGTGCTCTCCACACCAAGACCTTCAACTGCAACCGATGCGACCAGGCCTTCAAGGATAGAGACGTCTACAAAATGCATCTACTGCTAGCTGCAACATCAGACGGAAAGTGCACGGTTCGGTCCTTTAAGTGCACTCAGTGCGGGGAGACACTTTCATCAGAGCTGGAATTCACTCGTCACTATCGGGAACATGACAAGACCTGGTGGCACGAGTGTTTCATTTGCAACAAAACCTTCTACAGCAACTCTGCCCTCTGGAGACATCACAAAATTCACCTCAATCCCAGTGAGCCCAATCCCGATGAGTTTTTACACCCATGCAGTCTTTGTTCGAAAAAGTTCCCCACAGCCCGGCACCTGATGAGCCACATGCGGGCGCACTCCACCGAAAGACCATTCCAATGTGCGCAGTGTCCAAAGAGCTACAAACAGCGAAGCCAGCTCACCAGCCACGCCCTAACCCACACCGGGGAACGGAACCACAAGTGCCCGAAGTGTCCCATGACGTTCGTATACAAGTATTCCCTCACGCGCCATATGGACAGGTTACACACGGATGGGCGGTCCTACCAGTGTCCGGATTGCGATAGAAAATTCACCAGCATGTACAGTCTGCGGGACCACCGAAACATCCACTCCGTTTCGCGGCCCTACAAGTGCTCCGAATGCCCAATCACCTTTGTCTCGGAGCATGGCCTGAAGACCCATATGGGTGTGCACCGCAAAGATCCGGATGCCAAAGTGATCCCGAGACCCTACTCGTGCCATCTGTGCTGCAAGACCTTTATAAGTAAGCACGGCCAGAAGATGCATATGGCTGTCCATGATAGGTCgagttatacaaaaaaaaatctacaaGAGCCTCAACCTAGTCCTGAGAGTTAG
Protein Sequence: MDFVMPDSPPAFEEVADPADLEPHLLLTGGETAELKEYIWEEAFQRMEDAEAELRGESSSSDVRNSDQIKVPFNNTISVKNEPIDEEFLWDHSSKEAPSPSACPQIDSFIKAEDPEFYFEEDWEHAESDEESVIEVLSHSSRQEEDGDEEASQGSSEPSHNENSSFFKCDHCPRIFKYAKSLKNHCMSHTGVLPYNCKHCNQAFSQKGRYRKHMITHGTDPSSDLEYDSDDDKMFRCARCPKSFKFESNLRKHARLHTGNVPFQCSLCKEIFSQKARYEKHLQIPHSADGAPMDRPFKCTQCEKRFKLEHEFDRHIRGHKRTQKMLEKSKPPDKHADSIYKEIQVDGTIMLKCPVCANLFKSLRNLTRHRALHTKTFNCNRCDQAFKDRDVYKMHLLLAATSDGKCTVRSFKCTQCGETLSSELEFTRHYREHDKTWWHECFICNKTFYSNSALWRHHKIHLNPSEPNPDEFLHPCSLCSKKFPTARHLMSHMRAHSTERPFQCAQCPKSYKQRSQLTSHALTHTGERNHKCPKCPMTFVYKYSLTRHMDRLHTDGRSYQCPDCDRKFTSMYSLRDHRNIHSVSRPYKCSECPITFVSEHGLKTHMGVHRKDPDAKVIPRPYSCHLCCKTFISKHGQKMHMAVHDRSSYTKKNLQEPQPSPES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00504113;
90% Identity: -
80% Identity: -