Basic Information

Insect: Drosophila ercepeae
Gene Symbol: Zfx
Assembly: GCA_018150545.1
Location: JAECWL010000197.1:4522797-4524731[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0009 0.063 13.6 7.8 1 23 146 168 146 168 0.97

2 14 2.1e-05 0.0015 18.7 3.6 1 23 174 196 174 196 0.98

3 14 3e-06 0.00021 21.4 1.8 1 23 215 237 215 237 0.98

4 14 0.00011 0.0079 16.4 0.6 1 23 243 266 243 266 0.97

5 14 0.00028 0.019 15.2 3.6 1 23 277 299 277 299 0.98

6 14 0.012 0.85 10.0 0.4 2 23 332 353 331 353 0.95

7 14 0.00047 0.033 14.5 0.4 1 20 357 376 357 378 0.94

8 14 0.0016 0.11 12.8 1.8 1 23 391 413 391 413 0.98

9 14 2.4e-06 0.00017 21.7 4.3 1 23 419 441 419 441 0.97

10 14 0.00013 0.0088 16.3 1.5 1 23 454 476 454 476 0.97

11 14 1.2e-06 8.5e-05 22.6 0.8 1 23 482 504 482 504 0.97

12 14 1.9e-06 0.00013 22.0 2.6 1 23 510 533 510 533 0.96

13 14 2.9e-06 0.0002 21.4 1.3 1 23 539 561 539 561 0.99

14 14 2.8e-05 0.0019 18.3 1.0 1 23 567 589 567 589 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0009	0.063	13.6	7.8	1	23	146	168	146	168	0.97
2	14	2.1e-05	0.0015	18.7	3.6	1	23	174	196	174	196	0.98
3	14	3e-06	0.00021	21.4	1.8	1	23	215	237	215	237	0.98
4	14	0.00011	0.0079	16.4	0.6	1	23	243	266	243	266	0.97
5	14	0.00028	0.019	15.2	3.6	1	23	277	299	277	299	0.98
6	14	0.012	0.85	10.0	0.4	2	23	332	353	331	353	0.95
7	14	0.00047	0.033	14.5	0.4	1	20	357	376	357	378	0.94
8	14	0.0016	0.11	12.8	1.8	1	23	391	413	391	413	0.98
9	14	2.4e-06	0.00017	21.7	4.3	1	23	419	441	419	441	0.97
10	14	0.00013	0.0088	16.3	1.5	1	23	454	476	454	476	0.97
11	14	1.2e-06	8.5e-05	22.6	0.8	1	23	482	504	482	504	0.97
12	14	1.9e-06	0.00013	22.0	2.6	1	23	510	533	510	533	0.96
13	14	2.9e-06	0.0002	21.4	1.3	1	23	539	561	539	561	0.99
14	14	2.8e-05	0.0019	18.3	1.0	1	23	567	589	567	589	0.98

Sequence Information

Coding Sequence: ATGGATTTTGTCATGCCAGATAGTCCACCGGAGTTCCAAGAAGTGGCGCATCCCGCCGGTCAAGAACGCCACTTCATATCAAAGGGAGGAGCGGCCGCACAGTTAACGGAGTACATGTTGGAGGAGGCGTTTCAACAGATGGAGGATGCTGAGGCGGGGCTCAGAGGAGAGTCCTCCTCGCCAGACGTCAAGAACGAGCCCATTGATGAAGAGTTCCTGTGGGATCACAGTTTGAAAAAAGCACCCAATCCAAGTGCAAGCCCTCAAATCGATAGCTTTATAAAAGCAGAAGATCCCGAGTTTTATTTCGAAGAAGACTGGGAGCCTGCCGAGTCGGATGAGGAAAGCTTGATAGAAGTGATAGAAGAGGAGGATTGCGACGAAGAGGCATCTCAAGGCAGTTCGGAGCCCTCCCACAACGAAAACTCTTCCTTTTTTAAATGTGATCACTGTCCAAGAAGCTTTAAATACGAGAAGAGTCTGAAGAATCACTGCAGGAGCCACACCGGAGTCATGCCCTACCAGTGCAAGCACTGCAACCAGGCCTTCTCGCAAAAAGCGCGGTACAGAAGGCACGTGGCCACCCACGAAACGGATCCGAGTTCGGACTTGGAATATGATTCCGATGATGAGGACAAGATCTTCAGATGCGCCCGTTGCCCCAAAAGCTTTAAGTTTGAGTCAAATCTTCGAAAACACGCCCGGCTGCACACCGGAAACGTGCCCTTTCAATGCTCGCTCTGCAAGGAGATCTTTAGCCAGAAAGCACGTTACGAGAAACACCTCCAGATTCCTCACAGTGCGGACGGCACACCCATGGATCGGCCCTTTAAATGCAATCAGTGCGAGAAGAGGTTTAAGCTGGAACACGAATTTGACCGCCACATTCGCGGCCATAAACGTACGCAAAACGCCCTTGATAAGTCAAAACCAACAGACAAACGTGCAAATTCCATTTTCAAGGAAATCCAGGAGGATGGCACAATTATGTTAAAGTGCCCTGTTTGCGCCAACCTCTTCAAATCGATAAGAAACCTCACCCGGCACCGTGATCTCCACACCAAGACCTTCACCTGCAACCGATGCGACAAGGCCTTCAAGGATAGAGACGTCTACAAAATGCATCTACTGCTAGCTCCAACACCAGATGGAAAGTGCTCGGTTCGGTCCTTTAAGTGCACTCAGTGCCAGGAGACGCTTTCATCAGAGCTGGAGTTCACTCGTCACTATCGGGAACATGACAAGATCCGGTGGCACGAGTGCTTCATTTGCAACAAAACCTTCACCAGCAACTCCGCCCTCTGGAGACATCACAAAATACACCTCAATCCCAGTGAGCCCAATCCCGATGAGTTTACACACCCATGCAGTCTTTGTTCGAAAAAGTTCACCGCAGCCCGGTACCTGATGAGCCACATGAGGGCGCACTCCACCGAAAGACCATTCCAATGTGAGCAGTGTCCAAAGAGCTACAAACAGCGTAGCCAGCTCACCAGCCACGCCCTAATCCATACCGGGGAACGGAAGCACAAGTGCCCGAAGTGTCCCATGACGTTCGTATACAAGTATTCCCTCACGCGCCATATGGACAGGTTACACACGGATGGGCGGTCCTACCAGTGTCCGGATTGCGATAGAAAATTCACCACCATGTACAGTATGCGGGACCACCGAAACGTCCACTCCACTTCGCGGCCCTACAAGTGCTCCGAATGCTCAATGACCTTTGTCTCGGAGCATGGCCTGAAGACCCATATGGGTGTGCACCGCAACGATCCGGATGCAAAAGTGATCCCGAGACCCTACTCGTGCCATCTGTGCTGCAAGACCTTTTTAAGTAAGCAAGGCCAGAAGATGCATATGGTTGTCCATGATAGACCGAGTCGTACCAAAAAAAATCTACAAGAAGAGCCTCAACCCAGTCCTGAGAGTTAG
Protein Sequence: MDFVMPDSPPEFQEVAHPAGQERHFISKGGAAAQLTEYMLEEAFQQMEDAEAGLRGESSSPDVKNEPIDEEFLWDHSLKKAPNPSASPQIDSFIKAEDPEFYFEEDWEPAESDEESLIEVIEEEDCDEEASQGSSEPSHNENSSFFKCDHCPRSFKYEKSLKNHCRSHTGVMPYQCKHCNQAFSQKARYRRHVATHETDPSSDLEYDSDDEDKIFRCARCPKSFKFESNLRKHARLHTGNVPFQCSLCKEIFSQKARYEKHLQIPHSADGTPMDRPFKCNQCEKRFKLEHEFDRHIRGHKRTQNALDKSKPTDKRANSIFKEIQEDGTIMLKCPVCANLFKSIRNLTRHRDLHTKTFTCNRCDKAFKDRDVYKMHLLLAPTPDGKCSVRSFKCTQCQETLSSELEFTRHYREHDKIRWHECFICNKTFTSNSALWRHHKIHLNPSEPNPDEFTHPCSLCSKKFTAARYLMSHMRAHSTERPFQCEQCPKSYKQRSQLTSHALIHTGERKHKCPKCPMTFVYKYSLTRHMDRLHTDGRSYQCPDCDRKFTTMYSMRDHRNVHSTSRPYKCSECSMTFVSEHGLKTHMGVHRNDPDAKVIPRPYSCHLCCKTFLSKQGQKMHMVVHDRPSRTKKNLQEEPQPSPES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00546091; iTF_00615026;
90% Identity: iTF_00546091;
80% Identity: -