Basic Information

Insect: Drosophila vallismaia
Gene Symbol: -
Assembly: GCA_035047325.1
Location: JAWNPU010000025.1:2315728-2320434[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 9.2e-16 2.3e-12 46.5 0.0 7 74 498 561 492 563 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	9.2e-16	2.3e-12	46.5	0.0	7	74	498	561	492	563	0.89

Sequence Information

Coding Sequence: ATGAGCTCGCCAGATGACACTCCTGGAACGTCGAAGTCGCACAGGACACGACGTGAAAAGTCCTCGTCACGCAGCTCCAGCATTGAGTTCCTCGCCGACCGCCCGGCCTCTAGGAATGGTCATGGTGGTGCAGCTGCTTCCCCGTCGCCGGGACACTCCGATGGCCGCAGCCCCAGTGCTGGTCGCAGTCCCGCCTCTGCCATAGGACCCAGCAACATGCGTGACCGCCTCCTGTTGTCCAACGCCTTGGGCAGGGAGATGTCACTGAGCTCTGGGAACGAGGACACTACTACTAGCTCCTCATCGCCGCGCATGAATGGCGATCACGAGGAGAACGGTGGCGCCAAACACGGTtctaagaaaaagaaaaagaagaccAGGAAGTTGCGCGAACGCTTGCTGTCGGGTGAAGCCGCTCTGATCGGCTGGACGGGGAGCTTCCCCAAGCTCTCCACCACGCACAGCATCGACAGTCTCTCCGACCTGGAGTCGCAGTCGCCAGTCGAGCTGCGTGCGTTGGGCAACAGTGGTCTACGGGTGTTTCCTCGAGAAGAATTGCCGGGACCTGAGATGGCAGAGCCAGCTGAAGGCGTACTCGAAGTTGAAGCGGAAGTCTCGGTGGATCAAGTGGCGATGGAGaatccgcagcagcagcaacaacaacagccgcAGCAAGAtcaagagcagcagcagcagcaggcgctTGCCACGCCTCCATCGCCGGAGTCCTCTTTGTTCTCCAGCTTTGATTCAGAACGAAATGTGACAACGGTGGTAACGCCACCTGCGATTGAGGTTCGCTCTGATCGAGCCTCCCCAATCGATCAGCAAATCCAGACCGATCCTGGACCAgagccagaaccagaaccacaaccagagccagagccagaggcagAACTGCAAATAACTAGTACAAGTCTGACAACGACCTCGAGCTCGGCGTCAATTCCAAGCAACATTCAACAATCAGAGTTAGACAACCAGGAGAAAAATGAGTGTAAGCCGGAGCAGGTGTCGGAGCAGATGCCCAAGCAGGAGGAGAAGCTGGCCATGCAGGAGGAGGGGAAGCCAGAGCAGGACCCGGTACCGGTGCGCGACGACGATGTAGAAaagaagcagcaacagcagaagccagaccagcatcagcagcagcagcagcatgaAGCAGTAGAGAAGCCAGCCTTGGCAGGAGTTATTGAAatcgatgatgatgatgatgatgatgaagagGTTGTGATATTATCCCCAAAAACGTTAATTAAGAGAACAGCTAGTTCTTCCAAAGAGGTAATGGAAGAGCCGTCTGAGGAATCGCTGGCCAAACGCCCCAAGTCGGCTTGCAGCCAGGATTCTAACCAAGTAATTACAGAATCTGTGTCCGAGTTGGAGCTAGAGCTCCGCAAGGAGGCCAAGCCTCAGTCCATGCCGCCTCAGGTGGAGGCGCCGCCAACTCCCGCGGGCAACCTGAAACTGAAGCCAACCGACGAGTTCTATCGCCTGCCCTTCGCCTACGGCTGGAAAAGGGAACTTGTCCTGCCCAGCAACGGAAATCCCAAGCGTCGCACTGGCGATGTCTTCTTCATTTCCCCCACTGGAAAGAAGTTGCGCTCGCGCGAAGATATCATACCTTTGCTTGAGGGTGAACTGACCATTGAGCATTTCTGCTTTCAGCGCCAGCCGCAGATGGCTGGTTCGGACTTCGAACTAGTGCGTCGGGCCACACCCGCCCCGCTGCGAGGCAAGTCCCAGGGGCAGGCTCAGCCGCCGCCTGTTCCGCCGGTTACAGGAAAGCGTGTGCCCAAGCCAAAGGTGCCCAAGGGAGCCAGTCCTCCGTCTGAGGGCTGGACCGCCACTAGCGCAGTCAAAGGAAACGCTAGGGTTTTGGCCTCTAATGGAGGCAGCGGAGCGGCAGGAGCCGCTGGAGCTGGGCCATCGGGTTCATCCAGTTCTCGGAAGCGAAGCATCACGTCCAAGCCGCCGACTAGAGCCCAGAACTGCGTAACCTGTCAGGGACCCCTGGTGGTGTCCAAGCAGCAGGGATCTCCCAAGAGCAACATATGCCTGAACTGCTGGAAGTCCAAGATGGAGAAGCGCGAGAAACCAGCTGCCGCCCAGGCCATGGAAGTCAATGTGGATTCTCCACAGAACCAAAACGATAACCAGGACCAAGAGGACACTGTCAGCGGTGGCAGCATGTTGGAGGTCGGCGAGGAGATCGAGTTGCCTGGCCAGCTGCCGCCGGCGCAGCTTTTCAGCGATATTTCGGCACTGCGCCGTTCGCCCAGGGAACAGGAGGTGGTGGTGATTGGCGGCCGTAAGGCCATTGCCATCCTGGCTGATCCCCCACGCCCACGTATGATGAAAATTGTGCCCCGTCCGCCGGACTTGACCACCTATGATAAGATCTACAATAAGCGCATCCTGGCCAGGAAGACGCGGCAGGAAGTTATGGGGTACCTGGGCGATGCCCATAATGGCTGCCAGGTTCTGATGGCCGTCATGAAGACTATGAATCTGAAGGAGAGGGCCAACATGGCGCGAGTGTGCAAGACCTGGGCCATGGTGAGCCGCGAGATGAGCGTGTGGCGTTCGGTTTGCCTCCGGGACACGGTCATCGGCAACTGGGTGCTGTTTCTGCGCGAACTGGCGCGTCATCGCACCCGCGAACTGGACATGATGGGTGTTGTCAGCAAGCCCCAGACCCGAATGACTGGAGACTTGCGCATTTTGAAGACACTGCGTGTCCTGCGTACGGATCCCTCCGATTCGGAGTTTTTGCAGCTGGTCTTCCGGCATCTGCCGCATCTCCTAGAACTACGAGTGACCTGTGTGAGCGGCTCTCTGAGCCTGGCGAACCTGGAGCGCATGGAGGGGCTACGCGTGCTCCGCCTGCACATGACGGACCCAAAAGCCACGGCCAGCTCATTCGGTACGCTGGGAAAGCTGAAGAATCTGAAGGAGCTGAGCTTGCGCGGAGTTACCAACTTGGGAAAGATGCCATCGCAACTGCTGAAGTCGTTGCCTCACCTGGAGATTCTTTCGCTGGGATTCTGCCAGGATATGGACTGCGTAAAGCTGGGCAAGGATGTGCTGCCCATCCTAAAGTCGCTGCATACTTTCCGTCTCGAAAACGATCACCGCAGCATGGCCCTCTTCCCGGTGGACGACATTATGGCTGGCTTAGCGCAGGCTGGCGGGGTGCGCCGCCTGGAGTTGCTGAACGTGGACGTCGATGACGGTTTCAGTGCCATGCTCGCCAACTGCCCGACCATCAAGGAGCTGCTTCTGACTCCCAACTGCATGCACAACGCCGCCAACATGATCAACGCCGTGATGCAGGCCGTCAGCAGCAATGGGGAGCAGCTGAGCGTGTTCCGCCTGGGATTGGTCAACCAGCTGCTGAGTGTCACCGGCAACCTGTACAAGGGATCCGGCAAGGATGTGATACCAGTACGCCGCCCAGTGCCTGGCATACCGGCCAACGATGCATTGAACTGCTGTTCTCCGGAGGATAATTGCCTGGAGACGGACCATTCGCAGTGCGTGGCCTTCCTGCCAGTGGAGCGTCTGGAGTCCATTCTGCACCACATGGTGCCCCAGACCTGGCTCTCGGTAGCCAAGGTGGCCATGTGCGACACCACCAAGTTGCAGTTTCTGCCACAGCCACGCAACGTAAGCGTCGCCAGCCAAGCGCCGGCGCCGTCTTCAGGTCCATAG
Protein Sequence: MSSPDDTPGTSKSHRTRREKSSSRSSSIEFLADRPASRNGHGGAAASPSPGHSDGRSPSAGRSPASAIGPSNMRDRLLLSNALGREMSLSSGNEDTTTSSSSPRMNGDHEENGGAKHGSKKKKKKTRKLRERLLSGEAALIGWTGSFPKLSTTHSIDSLSDLESQSPVELRALGNSGLRVFPREELPGPEMAEPAEGVLEVEAEVSVDQVAMENPQQQQQQQPQQDQEQQQQQALATPPSPESSLFSSFDSERNVTTVVTPPAIEVRSDRASPIDQQIQTDPGPEPEPEPQPEPEPEAELQITSTSLTTTSSSASIPSNIQQSELDNQEKNECKPEQVSEQMPKQEEKLAMQEEGKPEQDPVPVRDDDVEKKQQQQKPDQHQQQQQHEAVEKPALAGVIEIDDDDDDDEEVVILSPKTLIKRTASSSKEVMEEPSEESLAKRPKSACSQDSNQVITESVSELELELRKEAKPQSMPPQVEAPPTPAGNLKLKPTDEFYRLPFAYGWKRELVLPSNGNPKRRTGDVFFISPTGKKLRSREDIIPLLEGELTIEHFCFQRQPQMAGSDFELVRRATPAPLRGKSQGQAQPPPVPPVTGKRVPKPKVPKGASPPSEGWTATSAVKGNARVLASNGGSGAAGAAGAGPSGSSSSRKRSITSKPPTRAQNCVTCQGPLVVSKQQGSPKSNICLNCWKSKMEKREKPAAAQAMEVNVDSPQNQNDNQDQEDTVSGGSMLEVGEEIELPGQLPPAQLFSDISALRRSPREQEVVVIGGRKAIAILADPPRPRMMKIVPRPPDLTTYDKIYNKRILARKTRQEVMGYLGDAHNGCQVLMAVMKTMNLKERANMARVCKTWAMVSREMSVWRSVCLRDTVIGNWVLFLRELARHRTRELDMMGVVSKPQTRMTGDLRILKTLRVLRTDPSDSEFLQLVFRHLPHLLELRVTCVSGSLSLANLERMEGLRVLRLHMTDPKATASSFGTLGKLKNLKELSLRGVTNLGKMPSQLLKSLPHLEILSLGFCQDMDCVKLGKDVLPILKSLHTFRLENDHRSMALFPVDDIMAGLAQAGGVRRLELLNVDVDDGFSAMLANCPTIKELLLTPNCMHNAANMINAVMQAVSSNGEQLSVFRLGLVNQLLSVTGNLYKGSGKDVIPVRRPVPGIPANDALNCCSPEDNCLETDHSQCVAFLPVERLESILHHMVPQTWLSVAKVAMCDTTKLQFLPQPRNVSVASQAPAPSSGP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00545958; iTF_00503983;
90% Identity: iTF_00545958;
80% Identity: -