Basic Information

Gene Symbol
Aef1
Assembly
GCA_035047365.1
Location
JAWNPT010000057.1:3314204-3315258[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0046 28 5.0 0.1 21 48 202 229 198 233 0.85
2 4 2.5e-05 0.15 12.2 0.0 21 52 230 261 227 263 0.89
3 4 0.028 1.7e+02 2.4 0.1 21 48 258 285 255 289 0.86
4 4 8e-05 0.48 10.6 0.1 21 47 286 312 282 319 0.88

Sequence Information

Coding Sequence
ATGATGCATATCAAGAGCCTGCCACACGCACATCAGGCCGCTGCGGCAATGAGCAATTGTGACATTGTCATTGTTGCCGCGCAACCGCAAACAACtagcgccaacaacaataacaacgataCCGTTACACAGGCCAGCCATGCCAACCATGTGGCGGCCGTTGCCCACGCCCAGCATcaggcgcagcagcagcaacaacagcagcagcaacaacaacaacaacaacagcagcaacaacaacaacagcaacaacaacacaatcaACAACAGCCGCCCGCGCCCTCAGAAATTGCATTGCCCTTTAATATGCATCTTTCGGGCATTGCACAGGAGGCGCACAGTGCCGCTCAAGCGGCCGCCATGGCAGCTGCGCAGGCCGCGGCAGCACAAGCCGCAGCAGCagaccaacagcagcagcagccaccgcAGTCCGCAGCGACGCTGTCGCATCTGGTGGCGAGTGCAACGCATAGTCCGCCCACACAACACGATGCTGGCCAGCATTATGTAACCAGCAATGGGCATGGCAACGATCCAGCCGCTGGCGAGGCGAACGGTTCGAATAGCAGCagtggaggaggcggcggcggtggtggccGGGAGCAGGAGAAACCGTTTCATTGCACGGTGTGCGATCGACGCTTCCGGCAGCTGAGCACGCTGACCAACCACGTGAAGATCCATACGGGCGAGAAGCCCTACAAATGCAACGTTTGTGATAAGACGTTCCGTCAATCGTCCACGCTGACGAATCATCTGAAGATCCATACGGGCGAGAAGCCCTACAACTGCAACTATTGTCCCAAGCATTTCCGTCAGCTCAGCACATTGGCCAATCACGTCAAGATTCATACGGGTGAAAAGCCGTTCGAGTGCGTCATCTGCAAGAAACAATTCCGGCAATCGAGCACGCTCAACAATCACATAAAGATCCATGTCATGGACAAGGTCTATGTGCCTGTCAAGATCAAAACCGAGGAGGACGAGGGGTGA
Protein Sequence
MMHIKSLPHAHQAAAAMSNCDIVIVAAQPQTTSANNNNNDTVTQASHANHVAAVAHAQHQAQQQQQQQQQQQQQQQQQQQQQQQQHNQQQPPAPSEIALPFNMHLSGIAQEAHSAAQAAAMAAAQAAAAQAAAADQQQQQPPQSAATLSHLVASATHSPPTQHDAGQHYVTSNGHGNDPAAGEANGSNSSSGGGGGGGGREQEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00518660;
90% Identity
iTF_00589756;
80% Identity
iTF_00614411;