Basic Information

Insect: Drosophila ustulata
Gene Symbol: Hr39
Assembly: GCA_035047365.1
Location: JAWNPT010000105.1:8103119-8107140[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.49 3e+03 -2.7 0.3 146 177 18 46 3 100 0.55

2 4 3 1.8e+04 -13.8 26.5 43 155 177 298 159 340 0.36

3 4 1.1e-22 6.8e-19 68.6 1.1 1 130 494 654 494 666 0.89

4 4 6.5e-83 3.9e-79 267.0 0.4 183 408 677 893 672 893 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.49	3e+03	-2.7	0.3	146	177	18	46	3	100	0.55
2	4	3	1.8e+04	-13.8	26.5	43	155	177	298	159	340	0.36
3	4	1.1e-22	6.8e-19	68.6	1.1	1	130	494	654	494	666	0.89
4	4	6.5e-83	3.9e-79	267.0	0.4	183	408	677	893	672	893	0.96

Sequence Information

Coding Sequence: ATGCCCAACATGTCGAGCATCAAGACGGAGCAAAGCGTGTCTCCAGGCGCCAGCGGCACCAGCTACCAGCTGCCCGTGAACATGTCTTCGACGccctcctccacctccacccGCCACAATGTCTCCGTGACGAACATCAAGTGCGAGCTGGACGAGCTGCCGACACCGAATGGCAACCTGGTGCCCGTTATAGCCAACTACAataatcacaatcacaatcataATCACAATCATGGCGGCAGCCTGCGCATTCCGCTCGGCATGCAGGCGGCCAAGGAGGATGAGTCCGACTCGGAGCCGGAGCTGGCCAGCATTGAGAATCTGCAGAAGGTGCGACGACGGGCGGCCGACAAGAATGGACCGCGACCCATGTCCTGGGAGGGGGAGCTCAGTGAGCCCGAGACGGCGGTCGACGAGGAGCTGATGGACACGGAGACGGTCATCAAGAGCGAGGAGCGAAGCGGCGGCCAAGTGTCGGGCATGATGCAGCCCATCAAAACCGAGCTGGAGCACATAGCTGGcgaattgcagcagcaacaacagctgcagcaggagcagcatcatcatcaccaccatcagcaacaccatcatcatcaccatcagcatcagcatctgcagcagcagcagcatcaacagcatcaacagcagccacagcatcTGCAGCCCATCAAGCAGAACTTTGGCCAGCAGCCGAACAAACTGAAGCTGGCGCCGACGCAAAGTGATCCCATCAACCTGAAGTACGAGCCGACGTCATCGACGACGACGCTCTGCGATCGCAGCAAGTCCAGCAGCGGCGGCCACTTGCCGCTGCTGCCCGCCAATCCCAGTCCAGATTCTGCCATACATTCCGTCTACACGCACAGCAgtccgtcgcagtcgccgctgACGTCGCGCCACGCCCCCTACACGCCTTCGCTGagtcgcaacaacagcgatgcGTCGCACAGCAGctgctacagctacagctccGAGTTCAGTCCCACCCACTCACCCATCCAGGCGCGTCATGCGCCCCCCGGTGGCGCCTCCCTGTTGCCCTCGGCCAGCAGTTATGCcaatggcggcggcggcggcggccctGCTGCACTGCATCATCACAGTGTGCTGTATCGTCCGCTCAACGTGGAGCCGCCGAACGCCGGCAGCTCGAGTGGTGGCCAGGAGGCGCAAAATCTCAGCATGGATGCCAGTGGCGCCGCGTTGGATGCAACGGCTGCGCTGCCTGCCTCGCCGGCGGGCATCTCGCGCCAGCAGCTGATCAACTCACCGTGTCCGATATGTGGCGATAAAATCAGCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCATGCAAGGGCTTCTTCAAGCGCACCGTTCAGAACCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGAAAGAAGTGTCCCGCCTGCCGCTTCGAGAAGTGCCTGCAGAAGGGCATGAAGCTGGAGGCCATACGCGAGGACCGCACCCGAGGCGGTCGCTCCACCTACCAATGCTCCTACACGTTGCCCAACTCGATGCTCAGTCCGCTGCTCAGTCCAGATCAGGCGGCTgccgcggcagcagcggccgcCGTTgtcaaccagcagcagcaacaacagcagcagcagcaacatcaccaACGTCTgcaccagcatcagcagcagcatcagccaCCGCAGAcatcacagcagcaacacggACCACTCAACGGGtttggcggtggcggtggcggcggctgcAGCGGTGGCAGCAGCGTTGGATCCAACTCCCTGCCGGCCAGTCCCAGTCTGGGCACATCTATCAAGACGGAGCAAGCGGAGCCGCTGAATCATCATGCGACGCGCGCCTCAAGCATTCCAGCCCTCCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATACACCGATGCTGAGTTGGCTCGCATCAATCAGCCGCTGTCCTCATTCGCAACTGGCGGCTCCTCGTCAGGCTCTGGCGGAGGATCGGGCACAGGAGGACATCACACTGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAATGGCGAGAACGCCAACCCCGATCTGATCGCCCATCTCTGCAATGTCGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTAATCAACTCGTGGTGCGAGCTCTTGCTCTTCTCCTGCTGCTTTCGTTCCATTGATACGCCCGGCGAGATCAAGATGTCACAGGGCAGGAAGATTACCTTGGCTCAGGCGAAAACCAATGGCTTACAGgCTTGCATTGAGCGTATGTTAAATCTGACGGATCATTTGCGACGTCTACGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGATACCACGGAGCTACATGAGGCGGTCAAGGTACGAGAGTGCCAGGAGAAGGCGCTGCAAGGTCTGCAGGCATATACGCTGGCACACTATCCCGACACGCCGTCCAAATTTGGGGAGCTATTGCTGCGCATTCCCGATCTGCAGCGCACATGTCAGTTGGGCAAGGAGATGCTGACGATCAAGACCCGCGATGGTGCCGATTTCAACTTGTTGATGGAACTGCTGCGGGGAGAGCATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGTSYQLPVNMSSTPSSTSTRHNVSVTNIKCELDELPTPNGNLVPVIANYNNHNHNHNHNHGGSLRIPLGMQAAKEDESDSEPELASIENLQKVRRRAADKNGPRPMSWEGELSEPETAVDEELMDTETVIKSEERSGGQVSGMMQPIKTELEHIAGELQQQQQLQQEQHHHHHHQQHHHHHHQHQHLQQQQHQQHQQQPQHLQPIKQNFGQQPNKLKLAPTQSDPINLKYEPTSSTTTLCDRSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPGGASLLPSASSYANGGGGGGPAALHHHSVLYRPLNVEPPNAGSSSGGQEAQNLSMDASGAALDATAALPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQQQQQQQHHQRLHQHQQQHQPPQTSQQQHGPLNGFGGGGGGGCSGGSSVGSNSLPASPSLGTSIKTEQAEPLNHHATRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSGSGGGSGTGGHHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00614235;
80% Identity: iTF_00614235;