Basic Information

Gene Symbol
hang
Assembly
GCA_018904565.1
Location
JAEIHY010018641.1:1202-10257[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.26 26 5.8 1.0 3 23 326 347 325 347 0.93
2 17 0.84 84 4.2 3.1 3 22 455 474 453 474 0.89
3 17 0.00056 0.056 14.2 3.3 1 22 597 618 597 620 0.90
4 17 0.064 6.4 7.7 0.1 2 21 632 651 631 652 0.93
5 17 0.00065 0.065 14.0 0.2 2 23 786 808 785 808 0.95
6 17 0.0019 0.19 12.6 0.1 1 23 816 839 816 839 0.96
7 17 1.5e-05 0.0015 19.2 0.1 2 23 926 947 925 947 0.97
8 17 0.00027 0.027 15.2 2.9 2 23 1032 1054 1031 1054 0.97
9 17 0.021 2.1 9.3 0.2 2 23 1063 1085 1062 1085 0.95
10 17 0.002 0.2 12.5 0.1 1 23 1098 1121 1098 1121 0.97
11 17 0.00012 0.012 16.4 1.1 1 23 1185 1207 1185 1207 0.99
12 17 0.0018 0.18 12.6 0.9 1 23 1215 1238 1215 1238 0.96
13 17 0.71 71 4.5 0.3 2 19 1246 1263 1246 1264 0.93
14 17 3e-05 0.003 18.2 1.4 3 23 1356 1376 1355 1376 0.98
15 17 0.0047 0.47 11.3 0.1 1 23 1411 1433 1411 1433 0.97
16 17 0.0061 0.61 10.9 0.4 3 23 1597 1617 1597 1617 0.98
17 17 9.5e-05 0.0095 16.6 2.1 1 23 1928 1950 1928 1950 0.98

Sequence Information

Coding Sequence
ATGCGCACACACTCTGTTATCAGGCAGCAGGACATTTCATATGATTTGCGCAGTCTTCTGTTTGACGGAGCGGGGGGCAAGATCACCTCACAGGATCGCCTGTCGCTGCACATATGCCACGCCTGCATCAGCTACCTGAACTCATGGCAGAGCTTCAAGAACCGCTGCCTCAGCTCGCAGACAAAGCAGCGCCAGTGGCTGGACACCAGCAACAAGAGCAAGCTCTTCAACTACCTGGACCTGAACAGCGCCGAAAACGGCGGAGCCTCCTCCGATCACCAGCAGCATTCGCAGCCGCATCAACCGCAATCGGAAAATGAGCTCGACGCGGAGAAGGCGATGGCAGCAGCGGCCACAACGGCCGCCAACATATTGGATGGCATTCCCTCGCTGAAGAAACGAAAATCCCTAACAGTCTATCCGCTGCTCTCGGGATTCTCCGGCCTAACCGGAATCGCTGGTGTGGGTGGTGGAATGGAGGGTTTGTCGTTGTCGCTGCCACTTGATTTCAGCCAAAGCTGCAGTACGGGTCACGTCCAACAGTCGGGTCTGCTGCCCCTGGCCACGGCCTCGGCTACGGCTACGGCAACGTCCACAGCGACGTCCACGTCCAATGCTGCTCCGGGCATCGCGTCAGCCACTGCCACTGCCACTTGTGGCTCTGGCTCTGCATCTGCATCAGCCTCCGTGGCGACGGCTCCGCTGCTCATGCCGCCGCTGCCAGCGTTGCCCATCAAAGATGAGCCCATTGACACGGACGACGACTACCAGATGAAGATGATAGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATATGCCGTTGATGGCCTCGGACTATGATTACACGGCACAGCATGGCGTTAATGCCCATTCCCTGGCCGCCGGCCTGCCACCGAATGCGGTGGCCAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCCTGCAGCCTGCAGTTCTCCACCCGAGCCAATGCCCGTCGGCACGAACGCAATCTGCACCCGAACCTCTTCCAGCTCTCCACGGACTCGCTGCACAACACGTCGGTGACGAAGCCAACGCCAGCTCTGGCCGCCGCCTTGGAAATCCAGCGGGCGGCAGCAGCGGCGGCCACCGCAGAGGCGAACCGTGCCGTGGGCGCTGCCGGCGGCAATATCACTCCGCAGAAGTACCGCCAGGTGGTGATGAACGCGTTCATCAAGTGCGAGGGCGGCGGCTACGACTACGACAATCCGGAGCAATACCGCCCGCTGCTCAGCCACGACAAGGTGGAGTTCATCGAGCAGAACGAGGAGTTCCTCGAGCAGTACCAGACGATGACCTGCCGCTGCTGCAGCAAGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTACCCGCTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCACCTCAAGAAGCGCAACTGCATAAATCTCTACAGAGTGCTGAATGCGCTGCGTGGCAAGACGCCAGTACTGCCCGTCTCCGACGCGGATGCGGATGCAGATGCGGATGCAGCTGATGCAGCGGTGGCTGACGAGGGAGCCACAGCTGTGGCGGTGGCAGATGCCGGTGCTGGCGTTGCCACGATGGCCAGTCCCACCGTAATGGTTACCGGAGAGACCGCCGGCACTCCCAGCGGCGGCGGCGAGCGCCCAGAGAAGCTGCGCGCCAAGGAACTGCTGGTCAACAAGCTGTACGAATGCAAGCTCTGCCCCAAGGGCTTCCGCACCAAGCACGAGTTCCGCACCCACGTCTACGACAAGCACGCGGATGTGCAGCGCAAGGACAACAACTCGATTCAGTGCAGCTTCTGCGGCCTGGACTTCGCCGATCCGGTGGACAGGCGGCGCCACTACAACAACATGGACTGCATTGTGCGGCTGCGCTGCATGACGTGCGACGCCAAGCTGGAGACGCACCAGCGCTTCCTCGACCACGTCTACCAGGATCATCTGGGCGGCGTGGGCGGCGGTGCCAGCAGTGATAATGCCTCCACCACAGGCAGCGGTCTGGCCAGGAGCAACAGCATGGAGCATTCGCCCGGCAAGAGGAGTCTGCTCGGTGCCCTGGGCATCGGCGTTGGCTCATCGGCGGAGGAGTCGCGCAGCAGCAGTGTGGCGCCCACGCTGACATCCTCCACGCCCAAGCCAGCGGGAGGCGCAACGGCCACAGCGGCCTCCTCTGCCGCCTCGGCGCCCAGTTCGGCGAATCGCGGTGATGCCTCCGCACCCAAGTCCCAGTACTTTTCGCGCATGCCGCAGGTGTGTCCCATTTGCGGGCAGCAGTACAACAACTACAACAACGTGCTGCGCCACATGGAATCGAAGCACCCGAACAAGCTGCCCGAGACCTACAAGTGCGTGCGCTGCGGCCTGGGCTACCCGCGGATCTCCTACCTGCGCGAGCACATGATCAACGTGCATGGCGTGGACAAGAACCGGCACTCGGGCGGCTTCGAGTACATCGTGAACGCCGATGCCGTGAAGCTGGCGGACGGCAGCACGCCGAATGTGTACACGGGTCGCTACGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACCCTCGACGAAGACGAGGAAGAAGCGACTGGCAGCGCGGCCAAGAAGATCCGCTTGGATGACAGCAGCAACAACAGCAGCCTGACCGGCGTGGCCAGTCAGCAGCAGAAGGAGTGTCCCATTTGCAATGCCGTGTTCAGCAACAACATTGGCCTCTCCAATCACATGCGCTCCCATTACACCGCCGCCAGCGTGGTGACCGCAGCTCTGGCGGCCGCCAATCGCATGACACCCAAATCGCTGACCATAACAGCAGCTCCAGCGGCAGCGGACGCAAGTCCAGAGGCATCTGGAATGGCCCCGGCGGCGACAATGGCCAGCAGCAGCAGCAGTGTTGTGCCGCCGGCAATGGCCAACCAAACGCCGCAGGAGCAGGCCGTCTTCCGACGCAGCTTGGATCAGGCGGCCGACCGTCGCTTCAGGCGAATGCGCTGCCGCATTTGCCAGCGGCGCTTCAGCTCGAAGAAGTCCTACCGCTACCACATGCTGACGGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTCGCCTACGAGAAGGGGCTGAAGGTGCACCTGTTCAAGGTGCACGGGCGGGCGATCAAGGACGAGATGATCATCAAGCAGTTCGAGTGCGAGGTCTGCTCGATTGTGTACAGCTCGGAGCTGGAGCTGCAGCAGCACAAGCGCAGTGTCCACAAGCTAAGCTCTGCCTCGGCATCGGCCTCCGCCTCGGCCTCTGCCTCAGCATCGGCGTCCGCCTCCACTTCCTCGAAGCTGGAGGACGATGTTTTGATGGACGAAGAAGGCAAGCCAGCAGCCGCCGCCGATCTGTCCACCCTTTCGGCCAACGCTTCCGGCCTGGGAGTGGGTGCGCCGCTGTACTGGTACCAGTGCAAGTACTGCCCCTCGAACTTCAACACCAACAAGAAGCTGGCCATCCACATTAACTCGCACGACGAGTTCGACTCGAACGATTACTCCTGCAAGGATTGCGGCAACGTCTACAGCGGACGCAAGAGTCTATGGGTGCACCGCTACAAGAAGCATCCCCAGGTCCCAGATCCGGCCGAGTGCTCGCTGTGCCGCAAGATCTTCTTCGATCGCCAGATGCTGGACAACCACACGCCCACCTGTAACCGCAAGCCCATCACCTCGACAGGTGCCCACCAGCAGCAGGATTCCCTGCAGCAGCAGCAGGCGGCGCTGCAACGCGCTGTTTTCCGCCACAAGACGGGCGACGACGACGACGAGGAGGAGGAGAATGATGGCCAGCAGCAGCAGCAGTTGGAGGAAGGTGATAGCAATGGTGGCGCAGCAGCGTTGGCATCAGGAAGCGCCGCTGTGGCAGCGGCGGCTTCTGTTCCGCCTCCACTGAAGATCCGCATACCGGAGGTGGCCTGCACCATCTGCGGAGCGCGGTTCACCGACCAGGAGCACTTCAGCAAGCACATCCAGAAGCACGAGCAGGAGCTGTACGTGGACAATCCGCTGGCGGCGATGTTCGACGACGGGCCGGCGGACGCGGGTCAGTTCCAGGTGGAGCGGCAGAACGAGAACGGGGAGTACGCGTGCGATTTGTGCGCCAAGACGTTCCCGCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTGCCAGCTCAGCTTCGCGACGAAGGAGCTGTGGATCGAGCACAAGCTGGCCGACGCGAAGGTGGTGCGTCCCTTCTGCCCCTTCCAGTGGGGTTGCGACCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAACCACATCAACAACCATCTCAAGGAGGAGGTCATTGTGCCGGTGGCCACCAAGGCGGCCATTGATCGGGAAGCGGAGGCAACGGCAGCGACAGCAGCAGCTGCGAATGCGACGCAATTAACAGCAGCAGCAGATGATGATGATGAAGTAGATCAAGACGGGGGGCAGAATGACAACAAGAAAGATGCGGCAGGAGCACGAAAAGCAGAGGAAAGCGATGACCTGGACGAGGAGGATAGCTCCGGCGAGGAGGAGGAAAGCTCAGGCACGGGAGACGACGAGGACGATGAGGACGATGACTCCGATGATGATGAGGGCGATGGCGGCGAAGGTGAAGATGAGGAGGGTGTGCAGCCTGGTCACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCGGACGACGATGATCTCGTGGAGGAGGTCTTTAGCTCGGATGATGATGAAGAGAGCGACGATGAGGACGATGTCGATGACGATGAGGATGAGGATGTGGAGGAACCGGAGCCAGTGGCAGTGGCAGTGGCGCTGTCGCCATCGCAGCCGCTGACGAATGGCAATGGCAATGGCAAGGCCAAGTCGAAAATGCCGCCGCTGATCGTGCACAGTTCCGACGATGACGACGATGAGGAGGAGGAGGATGATGGTGTTATGCCCATCGATGACATTATCGAGGAGGAGTTCTACGAGGAGGACGCCCTGCCGGTTGCCGACATCCAGGATGTGGATGATGCCATTGAGGAGGTGGATGACGATGATTTGGATGAGGGGGATGACGACGTGGAGATGGAGGAGGAGGAGGAGGTGGTATCGGCAGCCTCCTCGTCGGAGAGCGAGTCCACATCCACGACCACGTCCAATTCGCACTCGCATTCGCATTCCACGGGTGAGCGGCGCAAGAGGGCTGACGATCAGTTGAATGATCCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTTGATTCCCAGGAGCTACTCCAGAGCCACATCAAAAGCCATTTCCTCAATGGGCCAAAGCTCACAGTGGCAGCAGCAGCCGCCGCCGCAGCAGCCACAACAGCAGACGGCGGCAGTTCGGCAAAGACGAAGCCTGACGCCAAGTCAGCTCTGCTGGCCACCAACAACAACAATAAGAGCAGCAAGACTGTTGCAGCTGCAGCTGCCACAAACTGA
Protein Sequence
MRTHSVIRQQDISYDLRSLLFDGAGGKITSQDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDTSNKSKLFNYLDLNSAENGGASSDHQQHSQPHQPQSENELDAEKAMAAAATTAANILDGIPSLKKRKSLTVYPLLSGFSGLTGIAGVGGGMEGLSLSLPLDFSQSCSTGHVQQSGLLPLATASATATATSTATSTSNAAPGIASATATATCGSGSASASASVATAPLLMPPLPALPIKDEPIDTDDDYQMKMIDESDDMVDPTMFLERSEHEGDMPLMASDYDYTAQHGVNAHSLAAGLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSLHNTSVTKPTPALAAALEIQRAAAAAATAEANRAVGAAGGNITPQKYRQVVMNAFIKCEGGGYDYDNPEQYRPLLSHDKVEFIEQNEEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRGKTPVLPVSDADADADADAADAAVADEGATAVAVADAGAGVATMASPTVMVTGETAGTPSGGGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGASSDNASTTGSGLARSNSMEHSPGKRSLLGALGIGVGSSAEESRSSSVAPTLTSSTPKPAGGATATAASSAASAPSSANRGDASAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDEDEEEATGSAAKKIRLDDSSNNSSLTGVASQQQKECPICNAVFSNNIGLSNHMRSHYTAASVVTAALAAANRMTPKSLTITAAPAAADASPEASGMAPAATMASSSSSVVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSELELQQHKRSVHKLSSASASASASASASASASASTSSKLEDDVLMDEEGKPAAAADLSTLSANASGLGVGAPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAHQQQDSLQQQQAALQRAVFRHKTGDDDDEEEENDGQQQQQLEEGDSNGGAAALASGSAAVAAAASVPPPLKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCQLSFATKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKAAIDREAEATAATAAAANATQLTAAADDDDEVDQDGGQNDNKKDAAGARKAEESDDLDEEDSSGEEEESSGTGDDEDDEDDDSDDDEGDGGEGEDEEGVQPGHXXXXXXXXXXXXXXXXXPDDDDLVEEVFSSDDDEESDDEDDVDDDEDEDVEEPEPVAVAVALSPSQPLTNGNGNGKAKSKMPPLIVHSSDDDDDEEEEDDGVMPIDDIIEEEFYEEDALPVADIQDVDDAIEEVDDDDLDEGDDDVEMEEEEEVVSAASSSESESTSTTTSNSHSHSHSTGERRKRADDQLNDPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKLTVAAAAAAAAATTADGGSSAKTKPDAKSALLATNNNNKSSKTVAAAAATN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00478146;
90% Identity
-
80% Identity
-