Dtru005078.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila truncata
Gene Symbol
-
Assembly
GCA_008042515.1
Location
VNJQ01001263.1:12011-14401[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.067 5.8 7.6 7.0 3 23 251 271 249 271 0.96
2 12 0.0029 0.25 11.9 0.5 1 23 277 302 277 302 0.93
3 12 0.0049 0.43 11.2 0.7 1 23 309 334 309 334 0.94
4 12 4.4e-05 0.0039 17.6 2.5 1 23 343 365 343 365 0.97
5 12 7.2e-05 0.0063 17.0 0.1 1 23 372 394 372 394 0.97
6 12 0.0058 0.51 11.0 0.5 1 23 400 422 400 422 0.97
7 12 0.022 1.9 9.2 1.3 1 23 428 451 428 451 0.97
8 12 0.0095 0.83 10.3 4.5 1 23 457 479 457 479 0.96
9 12 0.00026 0.023 15.2 2.4 2 23 486 507 485 507 0.96
10 12 1.2e-05 0.0011 19.4 1.5 1 23 586 609 586 609 0.96
11 12 0.034 3 8.6 7.1 1 23 615 637 615 637 0.94
12 12 2.8e-06 0.00024 21.4 2.3 1 23 643 665 643 665 0.99

Sequence Information

Coding Sequence
ATGTCTATCTCTGACGGCAGAGAATACTCTATCCACACCGTGTGCCGCACCTGCCTGTCCGCTTTGGACAATACAGCGGCCTACGACCTCTTCCTGGTGCCGGGCCTTGCCAAgaagctgtgtgtgtgcacctCGCTGTCCGTGGAGCAGGCGGACGGTTTCCCCAAGAACCTGTGCACCCTGTGCTACACCAAGCTGAACGATCTGCACGAATTCCAGAAGCTGTGCGTGGATTCGGTGCAAAAGTTCCAGGATTTGGTGGCCAGCAACACCTTTGCCTGCCAGACGAACTTCGATGTCTTGGATCCCAGTGCTGCGGTTGCCGACCTGCcgggcgaggaggaggacaacGTTCACTTTGATCCGCTTTTAAACTCTAAAATCGAAATCATTGAAAACGAGGAGGATGTCTTCAAGATGCTGGAAACGGTGGAGAAGGAAGTGGAAGAGGTGGAAAAGGAGGACATGGACGTGGAGTTGGAGCAGCCCTTTGCCGAAGAAGAAGACTCCTTTGAGAGTGGCAACGACAATGACCAGGATGCAGACTTCCAGCTAAACAGCAGCGACGATGACATTCCGCTGGCCCAGCGCAGCCGGGGACGTCCACGGGGACGCAAGTCAAAGGCCAAGACCAAGCAGGAGAAGGTAACCGATGAGTCCAGCTCCTCAGAGGACTCGGAGGATGACAAGGGCAAGGCCAAGCGTAAAAGGATTCCAGCGGAAGAGCGCGATCGTCATCGTTTGATCGATTGCCACATTTGCCATCAGAAATTCAAGAAGGCCTTCCGCTACGAGGATCATATGAAGCACCACAACGATCTCCTGCCCTTCCAGTGCACCGTCGAGAGCTGCAAGAAGGGCTTCACCACCGCCAATGGGCTGCGCGTTCATGTAGAGCACGCCCACACAGACACCTCGGCCATGCATCCCTGCACCTACGAGGGCTGCAATAGATCCTTTGCCCGGCCTGTTTTGCTTAGCTTTCACATGAAGCGCGTCCATAAGGTGGATACCCCCCAAAGGGACTTCCCCTGCACTGAGTGCGACAAGGTCTTTCGCTGCCCCACCGCCCTCAAGAAGCACATGTACAAGCACACCGGCGAGGAGCTGCCCTTTGCCTGCGAAATCTGCGGCAAGCGGTTTCCTATTAACAGCGTTCTGCGCGATCATCTTTTGCGCCATGCGGGCATCAAGAATCATGTTTGTCCCTACTGCGGCGTTGGCAAGACAACGCGGCAGGAATGGAACAAGCACATTCTCACGCACACCAAGGAGAAGAAATATGAATGCCGGCAGTGCGATCACGCCTCCCACAACAAACAGGCTTTGGCCAACCATGTAAAGGTGGTGCACGAGAAGCGCAAGGATTTCGCGTGTCAATATTGTGGAAAGACCTTTGGCAAGTCGCACGCTTGCAAGATTCACGAGCGAAGTCATACGGGAGACAAATGCTGCGAGTGCAAGATTTGTGGCAAGGTTTTCTTGTTCGAAAAAGGCCTCACCAAGCATCTGAAGACGCACGAAAAGCGGGATCTACCCAAGACTCAACCGCTGAATCCTTTGATGGGCGGTGATCCTGCCacagccgccgctgcagccAGCACTTCGACGATTGCCAAGCCCAGTCCTCATCTGCGAGGCCGTGTGGAGCGTGTGGACATTGCCCAGTTAGCAGGGACGGTGGCCAATCCGATTCCATCGGTCAATCTGCCTTCATGGTCGCCGCAGGTCAACTTCACCAAGAAGGAGGGTCAGCACATTTGTCCCGACTGCGGCAAGGGCTTTAATCACGTGAGCAACATGAAGCTCCACTACAAGGTGGTTCATCAGAAGGTGAAGGACTTCTGCTGTCGCTTCTGTCCCAAGCGGTTTGCCAAGAAGCAGTATCTCCGCCATCATGAGTACATCCACACGGGCGAAAAGCCGTACGAATGCAAGGTTTGCGGCAAGCACTTCCGTCAGGAGCAGGTCCTCAAGACGCACATGAAGGTGCACGACAAGCCGCCCCGTCCGCCCGGCAAGCCAAAGGAGCCATCAGGGCCGAAGGCCGAGACCAGCACTTCTGTGAAGCGTCAGCAGCCGAAGAACTTCGAGCAATACCAAGATCCAGCGGCCGAACGGGCGGCTGCAACTGCTGAGCTGTTGGCCTATCAGATCGAGGAGAACGAGACCAAGCGTAAGGCGGAGGCGGAGCTAAGGAAGATCCAGGAAGCCGCCTTCGAACAGCTGAATAAGTTGCAGAAGCAAACGGGCACGTATCAGGGATTCTCCGCCCAAAAGGCCGAGGCGGAGGGCACCTCGACGGACCACCTCAAGTTGGACCATGTCTGA
Protein Sequence
MSISDGREYSIHTVCRTCLSALDNTAAYDLFLVPGLAKKLCVCTSLSVEQADGFPKNLCTLCYTKLNDLHEFQKLCVDSVQKFQDLVASNTFACQTNFDVLDPSAAVADLPGEEEDNVHFDPLLNSKIEIIENEEDVFKMLETVEKEVEEVEKEDMDVELEQPFAEEEDSFESGNDNDQDADFQLNSSDDDIPLAQRSRGRPRGRKSKAKTKQEKVTDESSSSEDSEDDKGKAKRKRIPAEERDRHRLIDCHICHQKFKKAFRYEDHMKHHNDLLPFQCTVESCKKGFTTANGLRVHVEHAHTDTSAMHPCTYEGCNRSFARPVLLSFHMKRVHKVDTPQRDFPCTECDKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGDKCCECKICGKVFLFEKGLTKHLKTHEKRDLPKTQPLNPLMGGDPATAAAAASTSTIAKPSPHLRGRVERVDIAQLAGTVANPIPSVNLPSWSPQVNFTKKEGQHICPDCGKGFNHVSNMKLHYKVVHQKVKDFCCRFCPKRFAKKQYLRHHEYIHTGEKPYECKVCGKHFRQEQVLKTHMKVHDKPPRPPGKPKEPSGPKAETSTSVKRQQPKNFEQYQDPAAERAAATAELLAYQIEENETKRKAEAELRKIQEAAFEQLNKLQKQTGTYQGFSAQKAEAEGTSTDHLKLDHV