Dtro006603.1
Basic Information
- Insect
- Drosophila tropicalis
- Gene Symbol
- -
- Assembly
- GCA_018151085.1
- Location
- JAECWH010000974.1:1367263-1379795[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 8.9 6.9e+02 1.1 0.1 2 13 352 363 351 372 0.81 2 13 5.4 4.2e+02 1.8 0.6 3 20 443 460 442 465 0.90 3 13 0.45 34 5.2 0.4 1 21 554 574 554 578 0.90 4 13 9.5 7.3e+02 1.0 0.2 2 23 621 643 620 643 0.88 5 13 0.31 24 5.7 2.7 1 21 648 668 648 669 0.95 6 13 0.91 71 4.2 0.8 2 23 688 709 687 709 0.89 7 13 0.00017 0.013 15.9 3.4 2 23 722 742 721 742 0.97 8 13 3.7e-05 0.0029 18.0 2.9 1 23 748 771 748 771 0.97 9 13 9.2e-06 0.00071 19.9 0.3 1 23 795 817 795 817 0.99 10 13 0.026 2 9.1 3.9 1 23 825 849 825 849 0.97 11 13 0.051 3.9 8.2 2.9 1 23 854 878 854 878 0.98 12 13 0.016 1.2 9.7 4.1 1 23 886 908 886 908 0.97 13 13 0.0004 0.031 14.8 3.2 1 21 914 934 914 939 0.93
Sequence Information
- Coding Sequence
- ATGAATTCGGCCGATTTAGACGACACTCACCTGTGTATAAAGTGTAATGGAAAAATTTTGGGACTTGCGAAATACATTGATCACCGTAAACGTAACTGTTCGCCTGTGGAAAAGCGAAACTCATCAAGTACTACTGCGCATGGTACAATGACAAGAACGTCACCACCAATAGTTAGTCGAAGCAATTTGGACCACACATACGATAGTTTTCATTTCGTTGAACCAGAGCCCCCAAGCAATTTTTTACAAAAAGCAGGTGAAAGTCATGGTGGAAAATCTTCTAAATCGCTGACCGAGGCTTATGATCTTCCATATGAGTTAGGGGCTGATGTGTTCTTTTCATCGCTGCAATTGCAAAGCGTTTCAACGGGTTGTAAGACCGTACCAGTAGGGCGGGCCGAGATTGGAAGATCCAAAGACGAAGACTGGCATGTTCCCCGTGGAGATCCTCTTCTCAAAGCATTAAGGGAACATGACGATGCGGTATTTAAACCTCTTAAGTTTGAACATGACTCCCCAGAGCTAAGTGATGATGAAGAAGAAGATGACGATCCCGATGAATTTGGGGAGGAAGTTGAAGAAGATTATGATATAAGACGACATTCGCCACCTACGGTTCCAGCTACACATACTGGAGGCAAGTGGAAGCCAGAACATCGGCCCCAACTGCGGCATCCGCACATGGAACGTATTTCCCCTAATTGGGATGAGCCTGGAGATGAAACGTATGCTCATCCACCGGCGGAATATACTAAGGGAAAGTGGATACCTGGTAGTAAGCATTTAGAGTATCGCGAAAACCATAATCTCACCAAGTGTGAGCAATTTGAAGACAGCTATTGGTGTAACATTTGTTGTCGTAAATTAAAAAGCCGTACCAATTACGATCAGCATCTAAAAAGTACCTTCCACTTAAAAAGGGCAGAAACAGAATGCCAACTAGCCCAGGCAACTCTTGGAACTGAGCTGACACTTAGTACACAGTTTTCTGTCGAAGTTCAACAGTCAAAAAAAGATAGAAGTCAATCAAGACAGCGTCGATCTAGTCGCCTCCGGTGTAGTCTTTGCCATTACAGTGTGCCACGTCAGTGGATTGGCAAACATCTCATCTCACATTATCACTATCGACGACTTCAACAGCAATCTCCGGGGCTGCGACAAAGCTCGCTTCAAGATATACTCAATCACATGAGTAGCATTGTAAAACAATCGCCTTTCCAGTGCATGCCTTGCCGCTTCTATGCCAATACAGAAGCTACTTTTCTAAAACATTGGCAATCAGAAAACCATCTGGAACTTACGATTAGACTTGGGGGAAGTTTCTGGTGTGATTACTGTCAGTTTGAGTGTAATTCAAATGAAGCCATGTGGGAACATTTTTTGGAATCAGCACACACAAGCGTCATTTCATCTCTTAATCGCTCTGTTCCGGTTTACATAGCTCAAAGAAGACATATTTACTGTTCTTGCTGCGGTATGCGGTTTCTCTATAACATACAATTACGTAGTCATTTTTCATCCGAACATCCTGGAGTCACGCCCACTGGAAGTGCTGCTGATGATTATCAGTGCCGTTTTCGCTGTCAATTCTGTCAATCACTTCATCGTTCTCGAGTGGCTCTGCAGCGTCACGAGAAGTACAAACATCAATTTATAAGATATTACTGTGCAATTTGTCGATTACAATTTGAAACTTCACTGGAAGCCCGCCGACACCGCAGTCTTATGCAACATAGGATGAAAACTAAACCAAATACGTCAATATCCCAGCCAGAGCAATATACCAATGATATATTTTCTAAAATTTTGGAAGATAGACCTCTAAGGCCTTCTGCCAACAAGCGGAGCATTTTTCAAAAACAGTGCATTGATTGCTCACAAACTTCTGAGTCGCCCCAACTTCTTGACCAACATCTGACTCAGGCCCATCTCTCTGAAAATCATCAATGCCTTAGTTGCGGATGCCATTTCCAATCTGCTCAGGCCTTGGGACGGCACACACGAAGCTGTAAACCAGCACCAACAACGTCTAAACAGGCGCTGCATGAAATGAACATGTGGCCTTGTGACAAATGCAGTTTTAGTTCACAGTATAAATCGGACTTAATCTATCATGAGTTTTTCCATACCCATGGAGACACCATCGACAAAAATGAAGTTCTTCAATGTCCACTATGCAGTAAAAAATTTCGCAAACATTCTCTAAGAGCACATTTACGAAATCACACGGATGAGAAGATTTTTCAATGCCCCGAATGTTTGCAAAAGTTTGCTCGGCGTCACAATCTTAAAAATCATCTAACTAGAATGCATGGTCAAAACCACAAAAATAAACCAAAACTTCAAGCTAAAAATAAAGAGTTACAAAAAAATCAAAAGAAATATCAATGTGAAACCTGTGGAAAAATATTAGCAAAAAAATCCTCCCTAAAAGCTCACGAGATGACTCACAATGCCAACATTGAAAGAAATTTTCATTGCCATTTTAAAGACTGTGCGTATTCAGGTTCCACCCAGGAAAATCTGAGAACCCACTTACTTTCACACTCCCAGGGAAGTTACAAATGTACCGAGGAGAAATGCTTGTACGTAGGAAAAAGTACTATGCATTTAAGAAGGCACCTCAAGTCACATAAGATAGAGAATACTCATTGGTTTTCCTGCAATCAATGCGATTTTAAATCTCGACTTAAGGGACATCTTACCAGACATACACTACAGCACTCTGGAGCTAAACCGCACAAATGCCCATACTGTGATTTTAATTGCAGTACAATAGATAACTTGCGCAAGCACATTATTAAGACAGGCAAGCATCCCGGAAGGTTTATTTATGAGTGCGACCAATGTTTAGCTGATCAAAACAATGCAATTTTTAAAAGCAACAGTTTTAAGGAATATCAAGCACATTTGATCACGCATTTACCAAAATGA
- Protein Sequence
- MNSADLDDTHLCIKCNGKILGLAKYIDHRKRNCSPVEKRNSSSTTAHGTMTRTSPPIVSRSNLDHTYDSFHFVEPEPPSNFLQKAGESHGGKSSKSLTEAYDLPYELGADVFFSSLQLQSVSTGCKTVPVGRAEIGRSKDEDWHVPRGDPLLKALREHDDAVFKPLKFEHDSPELSDDEEEDDDPDEFGEEVEEDYDIRRHSPPTVPATHTGGKWKPEHRPQLRHPHMERISPNWDEPGDETYAHPPAEYTKGKWIPGSKHLEYRENHNLTKCEQFEDSYWCNICCRKLKSRTNYDQHLKSTFHLKRAETECQLAQATLGTELTLSTQFSVEVQQSKKDRSQSRQRRSSRLRCSLCHYSVPRQWIGKHLISHYHYRRLQQQSPGLRQSSLQDILNHMSSIVKQSPFQCMPCRFYANTEATFLKHWQSENHLELTIRLGGSFWCDYCQFECNSNEAMWEHFLESAHTSVISSLNRSVPVYIAQRRHIYCSCCGMRFLYNIQLRSHFSSEHPGVTPTGSAADDYQCRFRCQFCQSLHRSRVALQRHEKYKHQFIRYYCAICRLQFETSLEARRHRSLMQHRMKTKPNTSISQPEQYTNDIFSKILEDRPLRPSANKRSIFQKQCIDCSQTSESPQLLDQHLTQAHLSENHQCLSCGCHFQSAQALGRHTRSCKPAPTTSKQALHEMNMWPCDKCSFSSQYKSDLIYHEFFHTHGDTIDKNEVLQCPLCSKKFRKHSLRAHLRNHTDEKIFQCPECLQKFARRHNLKNHLTRMHGQNHKNKPKLQAKNKELQKNQKKYQCETCGKILAKKSSLKAHEMTHNANIERNFHCHFKDCAYSGSTQENLRTHLLSHSQGSYKCTEEKCLYVGKSTMHLRRHLKSHKIENTHWFSCNQCDFKSRLKGHLTRHTLQHSGAKPHKCPYCDFNCSTIDNLRKHIIKTGKHPGRFIYECDQCLADQNNAIFKSNSFKEYQAHLITHLPK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00571507;
- 90% Identity
- -
- 80% Identity
- -