Dtro002738.1
Basic Information
- Insect
- Drosophila tropicalis
- Gene Symbol
- -
- Assembly
- GCA_018151085.1
- Location
- JAECWH010000574.1:16316264-16322432[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00031 0.024 15.1 2.0 1 23 158 180 158 180 0.97 2 13 0.73 56 4.5 1.6 3 23 188 209 187 209 0.93 3 13 0.00018 0.014 15.9 2.3 1 23 363 385 363 385 0.98 4 13 0.0011 0.086 13.4 1.9 3 23 704 724 703 724 0.92 5 13 0.045 3.4 8.3 1.4 1 23 730 753 730 753 0.98 6 13 1.3 98 3.8 1.6 2 23 790 811 789 812 0.92 7 13 0.0039 0.3 11.7 0.8 1 23 833 856 833 856 0.97 8 13 0.00086 0.066 13.7 0.6 1 21 1147 1167 1147 1170 0.90 9 13 0.14 11 6.8 4.7 1 23 1182 1204 1182 1204 0.98 10 13 8.6e-06 0.00066 20.0 2.1 1 23 1209 1232 1209 1232 0.97 11 13 0.0006 0.047 14.2 4.1 1 23 1245 1270 1245 1270 0.95 12 13 1.6e-05 0.0013 19.1 0.6 1 23 1275 1297 1275 1297 0.98 13 13 3e-05 0.0023 18.3 0.2 1 23 1304 1327 1304 1327 0.97
Sequence Information
- Coding Sequence
- ATGCCAGTACCAAGACAAATTGAGAGAAGAAGCAATGAAAAGGCAAAAGCGGAGCTTCAGTTCATCAAGTCCAATAAAGATTACGAATACGTTTGTCGTTGCTGTCTCAAATCGGACGCGGATTTTGTTCAACTGGATACGTTGATGGTATCGCGAAATTTGGAGCCAAGTGCTGAATCGGATAAAATCCCTTTATTGCGTTGCTTACTCTTTTGCATACGCACGGATAATAAACCCGATTTGCCCCAATTAATCTGCACGGAGTGTAGCAAGACTTTGCAAATCTCTTACTATTTTCTGCAAAATGCTTTGCGTGCTCATGAAATCCTTTGCCGTAAACTAAGTTCAGATAGGAAAAAACATTCGCGTCTTGGAGTGCAGCTTAATGGCAATTTTAGACATGAGACGGCGGCAAAGGAAGTCATTTCACCAGACAGCAAGGCGAGATCGAACAAGTCGGGTAATATTCGCCATGAATGCAAAATTTGTGGCACCGTGGTACACAATCGGATGGATCTTAAGCAGCACATACGCTTGCATAGAGATACAATCATCCGGAATTGCTCACTGTGCATTTTTAGTACGATCAAGCAGAGCCATCTTATGGAACATTATCGAGTGATGCACAATCTAACAACAGCTCAGGCCGAGGATCGCATTAATTTGGAACAACTTGAACAAAAACTGCAGGAAGGTCCTAAAGTTTGCACTCTGGAGGATATTGAAATGCTTATACCGACTGTATTGACACCCGAGGATTATGCTCAGCCAAAAAGTGAATATAATATTGAGCCACACTCAAAGCCCAATAAGGAAACAAGTGCAAATAATGTTAGCATTGGCACGGAATTTCTTGTCATGCCAGATGGATCACTACAACAAGTAAATGGTGGTGGAGTCCTCTTTGAATATATCGATGACAGCAAAAGTAATGTTGCACCCACAGGCAATTTAAATTTACAAACTCTTCTTGGAAATGACAATGAACCAATGGATATAGATATTAATGAGCTAATTGTGGAGGAGAATTTACCGCAAATAAATACCAAGCCGCGATCTGGAAAAATGGCAGCTGCTACTTTTAAGCATAAGTGCACAATTTGTTTAAAATCATTTCCAACTTTGGCCCGCTTAAAATCTCATCAATTAACCCACAATAATTTACCCAAATTTCATTGCGATCAGTGTAATTTCTTTACGCTGCATAGCTCTGATCTCGCCTATCATCATAGAGTAATGCATACGGAGCCGCCGACCCCAGAACCGGTTCCACCACCGGCTCCACCACCGGCTGTAGAACAGGGTGAACTCTTATCATGCGATCTGTGCCTGTTCGAGACAAGGATATCAAATGAACTGTACGACCATTATACTGACAAACACATGGTCCGTCCAACAGAGGTGCAATTGCGCCCCTGTTGGTCTGCTGAAGTAGAGCCAGTGGTAAACACGCCAATCTATCAACTGCCGGCCGATCAAGGGCAACATGTTGTTAATCCTTATCCAGAGCCTGTGCAGACAATTCTTCCAGAAACCGCCACAGATATTATTATGCAGCAGCCGGTACAGGCGAATACAACAGCAACCATAACACCAATGGGCGATATTAGTGTGGTTGTTGATGCAACACCATTATTTTTTCCCAATGGCACGCAAACCGCTGTGACTACAGTTGCCCCACTGCTACCACCGCTACCATTAACAACACCACAACCACCATCACCATTGCAAGCTCCTACAGCTCCTCCAGCTATTGTGGAAACTAACAATATCAGTAGTACCACAACAAACAATGCATTTGTTCCAGCATTTCCGGAAATATCAGCCAACGATAATATTGTCCAGACAGCTGAGCCAACTATTCCACCACTCCCAAACCCAAATTTAGCATCAACTTTTGGCGATATGCAAGACTTCATCGATAATACAGATGTCGCAGCCATATGCACCATACCAGCGGATGGTATGCCCGTTGTTGATGGCGATGATATAGTTATTGATAATAATAATATAAGTTTGGATTTTGATGCCGAAAATCTCTTTGGTGAATTCGAAGAGGAAGAGGAGGGTGGTGGAGAGGCAGTGTCGAGACATTTGCAAAAACCATATTGCATCTATTGCAACAAAAAGTTTACCAGCCAATACAAATTCGAGAATCATATGTTTGTTCATAGGGGTCTGGCTCCCTACCGCTGTGAATTGTGCACAAATCTTTACAATATGAAACGTTTACTAATACGGCATTACAAGACCGTACACAAACGCATGCCCACCCGAGATATGGTCCAGGCAAAGGGAGATAAAATAACAGTAGCTCGTTCAAATAAGGAAACCATCCAGGCCGAGGTCAATAAAGATCCAATGCTTATGTGCGCCAAATGTCCATTTGAGTGTGAGTCGGATGCGGATATGAAAAAGCATTTAAATGCTCATCATGGCATAAATGATGGTGTTTCCGTACATGCCAATGAAGTGTTTATTATACGTAAATTACCATTTGAGTGCCCACGTTGTATACGTTCGTTTGCTGCTAAACGGACACTAACACGGCATTTACAACGTAGTCACCTGGTGGACACCATAATTGAGCTAAAAAGTCCAGCCCCTACAATAACACCAAACGAAACCCAACCCAATGCGGAGACAAACGAAACCGTGCCATTGCACAATGCCGAAGATGCCACCGCAGATAAGGAAACTGACACCCCGTTGGAGGCTCCTGTGGCTGATGACACAGCGATGGCGGCTCCTGTGGCTGATGACACAGCGATGGCGGCTCCTGTGGCTGATGACACAGCGATGGCGGCTCCCGTTGTTAATGACACAGCGGTGGTTCCTGTTGCTGCTGACACATCGATGGGGGCTGCCTCTGCTAATGCTGAGATAGATGGAATAAATGTCGCCGAATGCGAAACCACCGTTCAAACTGAGAAAGAGGCTGAAGGTGAAGCTGCTGCAGCAGTGGAAAAAAATGAATCTACAGCCAACTCGAAGCCATTTATTTTAAAAGTAACGCCAACTGAAGTTACTACAACTACTGACACTACTACAACTACAACTACAACGGCGGCGAAACCAGCAGCAGCATCAGCTTCACCAACAGTAACCACAGCTTCTACATCTTCAACAATTTTCAATACACCGACACACTTCGATTTCGATTATGATTTTATGGGTGATAGTACATCTACGCCCAATGGTAACATCAATAACCCAAATCCTGATTCCAACAATATTAATACCAGTAGCACCACCACTACTACTAACAATAACAATAATAACAACAACAACAACACTACTACAACAGATGGCTATACACCAGCAGCCGAAGTGCTTCCCAGTCATGTACTCAATGGTAGTGACAAATTATTAACTGCCGCCACCATGGAGCCATCGCCCATTAAGGACGGACGAACGCGTCTTCCACGCACTCCGATCTTTGTATGCAAATTGTGCAATAAGACATTCGATGAACTAAGTAAACTGGCTAAACATGAAACCGATATGCATTCTGGCGGAGAACCGCGTCGTGTTGTCTTTCAGCACAAGTGTTCCACATGTCTTGCAACATTTCGAACCCTGACATTGTTGAAATTCCATATGAAACGGCATTTGGCACGCCGATATCAATGCAACCGCTGTCCCAAGTGCTTTATTAAAAAGCCGGAGCTGGAGCGACATATTTTAATGAAGCACGCAGAAAAGCATGACATGAGCAGCAAAGACAAAGCCTTCAGATGCTCACTGGATGGATGTACGAAGACTTTTAATTTCAAACATCATTTGGTTCGTCATCAAAATGCCGTGCATCTGAAGGTTCGTCATGTCTGCAATATTTGTGGAAAAGATATGGTAAATAGTTTCAATTTGAGAGCTCATATGCGCATTCATAGTGGCAATGGACAGTCGTACAAGTGTCCGAATTGTGATAAAACCTACGTGCGGCGCGGACCGCTTCGTCTGCATGCCCGTCAAGCCCATCAACTTGAGCTAACTGACAGCGATTGGGCCAAAATGTTATGCAATAATGTTCGCTCCAACAATTTGCACGTTAAAAAGACTTCGCGTAAAAAGAAAACTGTAGAGGCACCAGAAGCTGGCGACTAA
- Protein Sequence
- MPVPRQIERRSNEKAKAELQFIKSNKDYEYVCRCCLKSDADFVQLDTLMVSRNLEPSAESDKIPLLRCLLFCIRTDNKPDLPQLICTECSKTLQISYYFLQNALRAHEILCRKLSSDRKKHSRLGVQLNGNFRHETAAKEVISPDSKARSNKSGNIRHECKICGTVVHNRMDLKQHIRLHRDTIIRNCSLCIFSTIKQSHLMEHYRVMHNLTTAQAEDRINLEQLEQKLQEGPKVCTLEDIEMLIPTVLTPEDYAQPKSEYNIEPHSKPNKETSANNVSIGTEFLVMPDGSLQQVNGGGVLFEYIDDSKSNVAPTGNLNLQTLLGNDNEPMDIDINELIVEENLPQINTKPRSGKMAAATFKHKCTICLKSFPTLARLKSHQLTHNNLPKFHCDQCNFFTLHSSDLAYHHRVMHTEPPTPEPVPPPAPPPAVEQGELLSCDLCLFETRISNELYDHYTDKHMVRPTEVQLRPCWSAEVEPVVNTPIYQLPADQGQHVVNPYPEPVQTILPETATDIIMQQPVQANTTATITPMGDISVVVDATPLFFPNGTQTAVTTVAPLLPPLPLTTPQPPSPLQAPTAPPAIVETNNISSTTTNNAFVPAFPEISANDNIVQTAEPTIPPLPNPNLASTFGDMQDFIDNTDVAAICTIPADGMPVVDGDDIVIDNNNISLDFDAENLFGEFEEEEEGGGEAVSRHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKITVARSNKETIQAEVNKDPMLMCAKCPFECESDADMKKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIELKSPAPTITPNETQPNAETNETVPLHNAEDATADKETDTPLEAPVADDTAMAAPVADDTAMAAPVADDTAMAAPVVNDTAVVPVAADTSMGAASANAEIDGINVAECETTVQTEKEAEGEAAAAVEKNESTANSKPFILKVTPTEVTTTTDTTTTTTTTAAKPAAASASPTVTTASTSSTIFNTPTHFDFDYDFMGDSTSTPNGNINNPNPDSNNINTSSTTTTTNNNNNNNNNNTTTTDGYTPAAEVLPSHVLNGSDKLLTAATMEPSPIKDGRTRLPRTPIFVCKLCNKTFDELSKLAKHETDMHSGGEPRRVVFQHKCSTCLATFRTLTLLKFHMKRHLARRYQCNRCPKCFIKKPELERHILMKHAEKHDMSSKDKAFRCSLDGCTKTFNFKHHLVRHQNAVHLKVRHVCNICGKDMVNSFNLRAHMRIHSGNGQSYKCPNCDKTYVRRGPLRLHARQAHQLELTDSDWAKMLCNNVRSNNLHVKKTSRKKKTVEAPEAGD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00571373;
- 90% Identity
- -
- 80% Identity
- -