Basic Information

Insect: Drosophila tropicalis
Gene Symbol: -
Assembly: GCA_018151085.1
Location: JAECWH010000829.1:11124863-11128461[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 5.7 4.4e+02 1.7 2.5 3 17 61 75 60 76 0.88

2 13 0.006 0.46 11.1 0.0 1 23 211 236 211 236 0.96

3 13 2.6e-05 0.002 18.5 2.1 1 23 241 264 241 264 0.96

4 13 1.9e-05 0.0015 18.9 3.6 1 23 269 291 269 291 0.98

5 13 4.8e-05 0.0037 17.7 4.1 2 23 298 319 297 319 0.97

6 13 0.0011 0.083 13.4 2.1 3 23 331 352 330 352 0.95

7 13 0.0013 0.098 13.2 0.3 1 23 358 381 358 381 0.96

8 13 0.0066 0.51 10.9 0.2 2 23 392 414 391 414 0.96

9 13 7.7e-05 0.0059 17.0 0.2 1 23 442 464 442 464 0.97

10 13 4e-05 0.0031 17.9 4.7 1 23 471 493 471 493 0.96

11 13 8.6e-05 0.0066 16.9 0.2 2 23 500 521 500 521 0.97

12 13 0.00018 0.014 15.9 1.4 1 23 528 550 528 550 0.99

13 13 0.00022 0.017 15.6 2.4 1 23 556 579 556 579 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	5.7	4.4e+02	1.7	2.5	3	17	61	75	60	76	0.88
2	13	0.006	0.46	11.1	0.0	1	23	211	236	211	236	0.96
3	13	2.6e-05	0.002	18.5	2.1	1	23	241	264	241	264	0.96
4	13	1.9e-05	0.0015	18.9	3.6	1	23	269	291	269	291	0.98
5	13	4.8e-05	0.0037	17.7	4.1	2	23	298	319	297	319	0.97
6	13	0.0011	0.083	13.4	2.1	3	23	331	352	330	352	0.95
7	13	0.0013	0.098	13.2	0.3	1	23	358	381	358	381	0.96
8	13	0.0066	0.51	10.9	0.2	2	23	392	414	391	414	0.96
9	13	7.7e-05	0.0059	17.0	0.2	1	23	442	464	442	464	0.97
10	13	4e-05	0.0031	17.9	4.7	1	23	471	493	471	493	0.96
11	13	8.6e-05	0.0066	16.9	0.2	2	23	500	521	500	521	0.97
12	13	0.00018	0.014	15.9	1.4	1	23	528	550	528	550	0.99
13	13	0.00022	0.017	15.6	2.4	1	23	556	579	556	579	0.97

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACCTGTGCGCTTTCCATGTTTGTATGCGATTTTGAAAATGGAAACAATAATTTTTTGGACCTATTCCATCCCACATGCTGGCAAAGCGAAATGGGCCAAATACGCATGGAGTTTCTTAACTGGAATTTAAAGATATTACCGAATGATGGACTGCCTCAAAAGATTTGCAGCGATTGTTTTACAAAATTTTGTTCTTTATATACATTTCGGTTAACGTGCCAAGAGGCGCAAGTGAAACTATTAAATATATATGAGAAAATCGATGCCAGCAGTTTGGATGATCATTCGGAAGTGGAACTGGAACCGGATCTGGATACTGAGGAAGTTGATCTGGACTTAAACAATGATATTGATCCCACAAATGAAGCAACAACAAGAACAATGACGGTTTCAACTGAAGCAACACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCCATAGAAATCTATATAGATGCAGCGAATGTGGCAGATGCAACCGAAGAATATTCTTCTGAGCTGGTCATAAGCTACGCTTGCAAATTCTGTTTCAAGCCGCAAGAAAGCTTTCAGTTGCAACAACTGCTTCTGGAGCACATTAGTAGCGAACATGATCCAGAGCAACCATATAATTGTCCTGAACCCGAATGTGAAGAAGCTTTCCAGGATGCCGCCTCGCGAACTGTCCACATGAAAAGTGTTCACGTGGAAAAGCAATTTACTTGTGATGTATGTGGGAAGAAGTATGGGGATCGTCAGAATTTAAGACATCATGTCGAGAAATATCATTCGGACACGGATTTCGAATGCAGCATGTGTGAGAAGCGCTTTTTCACCAAAAAGAGTCTTAAATACCATATGAAATGGCATAGTCCTGATCGCCAATTAAAGTGTCGTCACTGCGATCGATTGTTTATCTCATCTGTACATCTCACTAAACATATGGCCACCCACACCCAAATGGCAAGTGCCCGAAAGAGCGAACATTGTGGACTATGTGGCAAAGCCTTTATACACATTAAAACTCTACGCTGGCATATCTATAGACAACATGGCGGAGAGAAGCCCTACAAATGTAGCAACTGTACCCAAGTCTTTGCATCGTATGCGGAAAAAAGGATACACATGCTGGAGGACCACATGGAGAATCTGACAGCCATTGAGAGAAGTGAGTGCATGCTCTGTAGACAGGTTTTTGGCAATGAACAGGACCTGGTTTACCATATGAAAAGGGAGCACTTAAAGAGCCCATCCGCTCCGGTGATTGTGAATAACAAGCGGGTTTTACAACAAAAACGCGAACGTCAGTATTCGGGCCTGTTCCAGTGCGATAGCTGTCCGCAACGCTTCAATATGAAATCTGCTCTGGAAAGGCATGCAGAGGTGCATTCCGAAAAGGATCGTCCTCATGCCTGTGCGCACTGTTCCAAGCGATTCAAACGTGCCCAGGATATGAAATGGCACATGAAAACGCACGAAAAAGTAAAGCCCAATGTGTGTGATGTGTGTGGCAAGGCGTTTGCCTTGAAGTATGTTCTAACCCAACACAAAAGGAGCCATGAAGTTCTCGAAAAGAACTTCAAGTGCAATATATGCGGACGAACGTATCTCTTTGAAAAATCGCTGCGTCTCCATCAACGAGTTCACACTGGGATGACCTATTACAACTGTGACCTCTGTCAGGAACGTTTTGTTACCCATATTAAGTTAAAAACTCATATGCAAAAGGTTCATGCCCAAACACAGGCAAAGGATTCCTCATTGGATAATTTAATTAACATTGTGATTTCCTAA
Protein Sequence: METCRTCALSMFVCDFENGNNNFLDLFHPTCWQSEMGQIRMEFLNWNLKILPNDGLPQKICSDCFTKFCSLYTFRLTCQEAQVKLLNIYEKIDASSLDDHSEVELEPDLDTEEVDLDLNNDIDPTNEATTRTMTVSTEATXXXXXXXXXXXXXPIEIYIDAANVADATEEYSSELVISYACKFCFKPQESFQLQQLLLEHISSEHDPEQPYNCPEPECEEAFQDAASRTVHMKSVHVEKQFTCDVCGKKYGDRQNLRHHVEKYHSDTDFECSMCEKRFFTKKSLKYHMKWHSPDRQLKCRHCDRLFISSVHLTKHMATHTQMASARKSEHCGLCGKAFIHIKTLRWHIYRQHGGEKPYKCSNCTQVFASYAEKRIHMLEDHMENLTAIERSECMLCRQVFGNEQDLVYHMKREHLKSPSAPVIVNNKRVLQQKRERQYSGLFQCDSCPQRFNMKSALERHAEVHSEKDRPHACAHCSKRFKRAQDMKWHMKTHEKVKPNVCDVCGKAFALKYVLTQHKRSHEVLEKNFKCNICGRTYLFEKSLRLHQRVHTGMTYYNCDLCQERFVTHIKLKTHMQKVHAQTQAKDSSLDNLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00555257;
90% Identity: iTF_00571325;
80% Identity: -