Basic Information

Insect: Drosophila tropicalis
Gene Symbol: zfh1
Assembly: GCA_018151085.1
Location: JAECWH010000848.1:15558432-15562646[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.9e-05 0.0015 19.0 1.3 1 23 144 166 144 166 0.97

2 15 0.00079 0.061 13.9 1.2 3 23 174 194 172 194 0.94

3 15 5e-05 0.0039 17.6 0.1 1 23 353 375 353 375 0.98

4 15 0.0006 0.047 14.2 0.8 1 23 381 403 381 403 0.98

5 15 0.00018 0.014 15.9 3.9 1 23 435 458 435 459 0.94

6 15 0.0013 0.1 13.2 0.2 1 23 487 509 487 509 0.95

7 15 0.011 0.85 10.3 1.6 1 23 515 538 515 538 0.97

8 15 0.025 2 9.1 0.4 3 19 547 563 546 564 0.95

9 15 0.00015 0.012 16.1 5.6 1 23 573 595 573 595 0.97

10 15 0.045 3.5 8.3 0.4 2 23 601 622 600 622 0.96

11 15 8.9e-06 0.00068 20.0 1.0 1 23 631 653 631 653 0.98

12 15 0.001 0.078 13.5 0.1 3 23 661 681 659 681 0.97

13 15 5.4e-05 0.0042 17.5 0.5 1 23 687 709 687 710 0.95

14 15 0.15 12 6.7 0.2 1 23 720 742 720 742 0.96

15 15 0.0054 0.42 11.2 0.2 1 23 1300 1322 1300 1322 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.9e-05	0.0015	19.0	1.3	1	23	144	166	144	166	0.97
2	15	0.00079	0.061	13.9	1.2	3	23	174	194	172	194	0.94
3	15	5e-05	0.0039	17.6	0.1	1	23	353	375	353	375	0.98
4	15	0.0006	0.047	14.2	0.8	1	23	381	403	381	403	0.98
5	15	0.00018	0.014	15.9	3.9	1	23	435	458	435	459	0.94
6	15	0.0013	0.1	13.2	0.2	1	23	487	509	487	509	0.95
7	15	0.011	0.85	10.3	1.6	1	23	515	538	515	538	0.97
8	15	0.025	2	9.1	0.4	3	19	547	563	546	564	0.95
9	15	0.00015	0.012	16.1	5.6	1	23	573	595	573	595	0.97
10	15	0.045	3.5	8.3	0.4	2	23	601	622	600	622	0.96
11	15	8.9e-06	0.00068	20.0	1.0	1	23	631	653	631	653	0.98
12	15	0.001	0.078	13.5	0.1	3	23	661	681	659	681	0.97
13	15	5.4e-05	0.0042	17.5	0.5	1	23	687	709	687	710	0.95
14	15	0.15	12	6.7	0.2	1	23	720	742	720	742	0.96
15	15	0.0054	0.42	11.2	0.2	1	23	1300	1322	1300	1322	0.97

Sequence Information

Coding Sequence: ATGAACAATTCGAGTTATGGTAGATTCCAATGGATACAGCACCACGCCTCTGGTGACGAGACGGAGGCGGAAACCATAGTCGGAGGTGATAGTGAGCCCGCAACTGCTTTTTTGGTAAATGGCACTGCCCCGGACGAAGATCTCGATCATATGGCGGCCGAAAATCTAATTTTCATGGCACGCGATGGCCAGCTGGATGAAATTATAGCTGGGAATGATGCGGATTCGGGCGGTGCAGTGCTAGCCTATGCCTCGGACAAACCTTTCGATGATGAAGCTGAGGTGGTCACCGAAGAGGTCATAACCGATGACTGGGTCCAGCATCAGGGGGCGGAGAGGGTGGAAATTGCTGCAGAGCAAATAGCTGGTACCACAAGTTCCCAAGAGCTGTTGGATATGGAGCAGGATGAATATACAGTGCTTCGTCCATATCCCTGTGATTTCTGCAGTCGCCGGTTTCGCAAAAAGGGCAGCCTCAACAATCATATGCAGGCCCATCAGAATGATCGACCCCACCTCTGCAAACTGTGTGGCGCCCGCTTTTCACGTCGCGGGGAATTGATTAGCCATTTTAAAGCCCATGCGGAGGCCCAGGATGCAGCCGATGCTGAAGCAGCAGCAGCTGCGGCCGCTGCTTCCGCAGCGGCGCCATCTTTATCGTGTGCCTCCGTAAAGTACGAACAGCAACAGCAACGCCAACTGGATGATCACTACTACGAGCAGGATTGGCCATTGTATCAGCAAGAGCAGAATCAAGAGCAGCAATGCTTGATCGTATCCAGCAGTGAGGTTCCGCAACTGATGCAACAAACGAACTATATGACCGAAAACAACACCAATGTGGCCACACCAGTGGCATCTGCATCTAGAGGCAGGATAAGTCGACTAAAGCCCAAAGAGGAGACCAGTCAGTATATTGTGATTACCGAGAATGTGCAGAATGAACCGGCCCAGGGCCAGGTGGTGGCCACATCCACTTTAGTTGAACCAGACGTTGTGTCCGCCTCAGATCCTCCTGAACATCTTAATTTCCCAGTCCTAGATGAGGGCAAACCATTTGTCTGTCAGGAATGTGGTTTAGCCTTTGCCCGAGAGAAAGCTTTGGTGTCTCATATTAAGAATCACCGCGTGGACTCACCCTTTGAGTGCAACCAATGCCAAGAAATGTTTTGGGATAACAATAGCCTGCAGGAGCATCAGAAGACACATCAGTTTGAGGAGAGTAACTCGGAATACGATCCGGCTTCAGCGTCAGATAGTGGCAGCGAATCGGAACAGGAGGATCAGCAGCTTTATGGTGAATTCTATTGCAACGAATGCGGCATTTCCTTTCACAGGCAGAATCTACTACGTCGCCATGCCAAAGAGCAACACCACAAGTCCGCCAATGGATCGCACCCATCAGAGAGCCATCAGCAGGAATTTGGAGACGCGGAAAATGCCACGGAAGGCCCTCCGCATAGTTGTCACACATGTGGCAAAGCTTATCCCAGCGCCCTCGAGCTGCTTGCTCATGCAGAGATTCATGCCCGTTTTCCGCCCTTTAAGTGTGTCCTGTGTGGAATGAGTTTCTATGAGGAGCAAGCTATTAAGCGTCATTTGCACACCCGCCATCCCCAAGAACTAAAGCCCAATTCATGCGTGCTATGCGGCAAAGAGTGCAGAGATAGAAAGGCTCTTATCAAACACGCCTGGGACCACTCACGTGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAAAACTTTCACAACAAAGCGCGACTGAAGCGCCATATGGCATCTCATAGGGATAAATCGGTGGTTTGTGAGGTTTGCCAGGAAGAATTCCCCGATGGGCGAACTCTATCAAATCATCGACACTCACACAGCACCACTTCGCCAGGCAAACTGTTTCCTTGTCATGAATGTGGAAAAACATTTGGCTCACGCAGCTCCCAGCAGATCCACGTACGTATCCACACGGGGGAACGTCCATATGGCTGTCGCTATTGCTGGAAAGCCTTCGCCGATGGCGGAACCCTGCGGAAACATGAACGCATTCACACTGGCGAAAAGCCGTATGCCTGCTCGGTCTGTCCACGTGCCTTCAATCAGCGTGTGGTTCTTCGTGAGCATATTCGCTCCCATCATTCGGGTCTCGATGTGACAAAAGGAACCTATCACTGTACAGTCTGTTCGGCCGACTTACCCTCATCCAACGAGTTGATCCAGCATCTCATCCAGCATAGTGACTCAAACACAGCCAAGCAAAGAGCGCCCATTACTGGTCCACGGAAATACAAACGTCGCCGCAAGTTACAGCCTCATGAAATAGCTCAGATGCGGGATGAGCACCAAGATGTTGAAACTGCCGGCGATGATGGTTTAGTGGAGGACGAGGGCGACGAATATGCCACTGACATTGACATCTGTGACTTTGATATGGAGAATGTGGATGATATCTTTGATATGGCTTCATCTACGCATACCAACAAAAAAGAAAGATGCAAGAAACCCGTCACAAAGGACACCAAACCAGTGCGCAATGGAACCGGGGCCAAGGGGCCGGATAAATCTACGTCCAAACAACGCTTTGATTCCAATAGTAGTCAGTCGGAGCGTATGTGGGATGAGAAACTTTTGCAGGATAATCAAGTGGCCTTCTTTCAAATTGACTCGCTGGTGGTGGTTAACGATACCACTCTCGAACCAGCAAGCTCTGTGAGTTGTTCTAACGGTGTGGGAAATGCGGCAAGGACGCGAAGAGCTGTCAAACAATCAGCCCAGACCAAATTGCCTCCTCCAGTTGATAGTAAAACTGATGTGATTGCCACTGTCGCAACCTATGCTGGCAATACGAATAACCGCAGCAAAAAGAAGACTACAAGCAAACCAAGTGCCTCCACCACCTCGCGTCCTCGTATGATACACACTGAAAAGACTAAGATGCCACGAGCCACGGCCACAGAGAGCTCGAATGCTGGTGGTGGTGGAGCGGCAGGGGTGGGTAGCACCAAAAGGACTCGCGCCAAAACATATATAACTCGTACAGAGACCAACAATCTGGACTTGCTTGCGGGCGGTGGCGGCAATCGTGGCAAAGCGGGTTCCACCGCTGCTACGAATATTGTAGACGACTATGAGATCATTTCCCCTGCCACTCAACCTCCTAATCAGATAAGTTCGAGTCCGCTGCACATAAAGCAAGAACAGGAGCAACAGCGTGTTCAGATGATGTACGACGATACGCTCCTCATTGATGCAGCACTCTTGCGTGAGAAGACCTACGAGAAATACAATCCCAGCATTGTTAATGATTTGGAGGAGATTCTTCGGTCACCACTTAAAAACGATCGCAACACGAGTCGCCTGCGTTTCACCAGTGAATCCTCTACAACTCCACAGTTCCTGCCCGGTGAGGAGCAAAACCTGATTAAAATTGAACCAACTTCACCCGATCTACGTGAAATGGTTGAGGGCCAACAACGGATGACAAATTGTAATATTGCCACTCCCACAACATCCTTATCATCGTCGTCAACAGCAGCATCCAATTCCCGGCATTTGCGTCAACTTACTGCCAACAGTCAGAGGACAGCAGGCAACAAGCGTCCTAGCAGCAGCACCAGCACCTCCAGTAAAGCTGCAACAACTGCCTCAACGAGTTCCGCAAAGAAACCCGCTACTTCCACATCCACAGTGGCGGCCATCAAGGCCACCAGAAACACAGTCAGCAATTCCTATCTTAGCTATGGAGTTGGGGTAGATGCCTATAATGTGAATGTACCTGCCAATGCCAGCACTGCCGATGTGAATTCTGGGTTCTTTTCCATCTCAGAAGTTGTCTCCGCTGCCGAGACAGCCGATGCGGCAGCCAAAGAAGCAGCTGCCGGCAAAACGGAGCGCAAGACGCGAAGCTTCGAATGTGAAATGTGTTCGGCCATATTCTATGATCGAGCCCAATTGCTGGACCATGTTCACATTCACATTTAG
Protein Sequence: MNNSSYGRFQWIQHHASGDETEAETIVGGDSEPATAFLVNGTAPDEDLDHMAAENLIFMARDGQLDEIIAGNDADSGGAVLAYASDKPFDDEAEVVTEEVITDDWVQHQGAERVEIAAEQIAGTTSSQELLDMEQDEYTVLRPYPCDFCSRRFRKKGSLNNHMQAHQNDRPHLCKLCGARFSRRGELISHFKAHAEAQDAADAEAAAAAAAASAAAPSLSCASVKYEQQQQRQLDDHYYEQDWPLYQQEQNQEQQCLIVSSSEVPQLMQQTNYMTENNTNVATPVASASRGRISRLKPKEETSQYIVITENVQNEPAQGQVVATSTLVEPDVVSASDPPEHLNFPVLDEGKPFVCQECGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNNSLQEHQKTHQFEESNSEYDPASASDSGSESEQEDQQLYGEFYCNECGISFHRQNLLRRHAKEQHHKSANGSHPSESHQQEFGDAENATEGPPHSCHTCGKAYPSALELLAHAEIHARFPPFKCVLCGMSFYEEQAIKRHLHTRHPQELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVTKGTYHCTVCSADLPSSNELIQHLIQHSDSNTAKQRAPITGPRKYKRRRKLQPHEIAQMRDEHQDVETAGDDGLVEDEGDEYATDIDICDFDMENVDDIFDMASSTHTNKKERCKKPVTKDTKPVRNGTGAKGPDKSTSKQRFDSNSSQSERMWDEKLLQDNQVAFFQIDSLVVVNDTTLEPASSVSCSNGVGNAARTRRAVKQSAQTKLPPPVDSKTDVIATVATYAGNTNNRSKKKTTSKPSASTTSRPRMIHTEKTKMPRATATESSNAGGGGAAGVGSTKRTRAKTYITRTETNNLDLLAGGGGNRGKAGSTAATNIVDDYEIISPATQPPNQISSSPLHIKQEQEQQRVQMMYDDTLLIDAALLREKTYEKYNPSIVNDLEEILRSPLKNDRNTSRLRFTSESSTTPQFLPGEEQNLIKIEPTSPDLREMVEGQQRMTNCNIATPTTSLSSSSTAASNSRHLRQLTANSQRTAGNKRPSSSTSTSSKAATTASTSSAKKPATSTSTVAAIKATRNTVSNSYLSYGVGVDAYNVNVPANASTADVNSGFFSISEVVSAAETADAAAKEAAAGKTERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00501217;
90% Identity: iTF_00503414;
80% Identity: -