Basic Information

Insect: Drosophila trichaetosa
Gene Symbol: RREB1_1
Assembly: GCA_035043205.1
Location: JAWNNE010000282.1:313165-319884[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.037 2.4 8.8 0.8 1 21 258 278 258 280 0.93

2 13 0.00034 0.023 15.1 0.2 1 23 290 312 290 312 0.98

3 13 0.00026 0.017 15.5 7.2 1 23 318 340 318 340 0.98

4 13 0.9 60 4.4 1.5 2 20 568 586 568 588 0.93

5 13 0.017 1.1 9.8 0.2 1 23 732 754 732 754 0.97

6 13 1.3e-05 0.00084 19.7 0.7 1 23 764 786 764 786 0.99

7 13 0.00085 0.056 13.9 2.0 1 23 792 815 792 815 0.97

8 13 0.003 0.2 12.2 2.0 1 23 1076 1099 1076 1099 0.95

9 13 8.9e-05 0.0059 17.0 0.3 2 23 1483 1504 1482 1504 0.97

10 13 0.15 9.9 6.9 6.3 1 23 1510 1533 1510 1533 0.97

11 13 9.6 6.4e+02 1.2 3.4 1 23 1653 1676 1653 1676 0.78

12 13 0.0086 0.57 10.7 0.5 3 23 1736 1756 1734 1756 0.96

13 13 0.0014 0.091 13.3 4.8 1 23 1762 1784 1762 1784 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.037	2.4	8.8	0.8	1	21	258	278	258	280	0.93
2	13	0.00034	0.023	15.1	0.2	1	23	290	312	290	312	0.98
3	13	0.00026	0.017	15.5	7.2	1	23	318	340	318	340	0.98
4	13	0.9	60	4.4	1.5	2	20	568	586	568	588	0.93
5	13	0.017	1.1	9.8	0.2	1	23	732	754	732	754	0.97
6	13	1.3e-05	0.00084	19.7	0.7	1	23	764	786	764	786	0.99
7	13	0.00085	0.056	13.9	2.0	1	23	792	815	792	815	0.97
8	13	0.003	0.2	12.2	2.0	1	23	1076	1099	1076	1099	0.95
9	13	8.9e-05	0.0059	17.0	0.3	2	23	1483	1504	1482	1504	0.97
10	13	0.15	9.9	6.9	6.3	1	23	1510	1533	1510	1533	0.97
11	13	9.6	6.4e+02	1.2	3.4	1	23	1653	1676	1653	1676	0.78
12	13	0.0086	0.57	10.7	0.5	3	23	1736	1756	1734	1756	0.96
13	13	0.0014	0.091	13.3	4.8	1	23	1762	1784	1762	1784	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcagcagccacaacagcaacaatcgcacacagcagcagcaactgcagtagcagcagcaacacaagaGGATGCTCGGGATTTGGGATTAATAGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGCCGTCGCGCAAGCGAAAACTGCGACAgccacaccagcagcagcaacagttgccgctctccgatgaggagcagcagcagcagcagctgttggatTCGTCAACGCAGCGACCGCGTCACAAGCAGCGGCGcagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGCAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataacaatatcaacaacaatatcagtagtagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcgtcggcaGCGCAGCATGCGTCAAGCGTTAGCAGTTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGgcctcgcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcgacgccAGCAACATGCGGGCGGAGCAGGCGCAACTAGCTCGGGATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGTTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacaacaacaataataataataataagaatgaAGATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATTGAGCAACAAACAGCGACGCCTCAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGATGTGGACAGCGTTGAGAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTATGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGACCGAactggaggagcagcagcagcagcatgaggAGGACCACgaacagcagcacaagcaggaGGAACAGGAGCACACCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAAGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAACCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCATACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGGGAGGATGTGAAACGTGCGATCGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGAGCGATGCCGATATGCTAACCGAGCTGAGCGGCTATCGCTGTCCCACACCCACGGAGCACAGCTCCTCAGCTAGCTCCTCGTCACAGCTAAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTAAaggtaacagcagcagcaacggtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTTGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAtgaattgctgctgcagcagcaacaccaacagcagcagcaacaacagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCACGCCGCCGCCAcctgcaacggcagcaacagcagcagacaagtcaatgccaacaaatccagcagcagcagccggcgcaacagcagcaacaattgctgcaatgCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCATCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcaactgccgcAGCAATGAGTAAtctcagccagcagcaacagttgcagcagcaacagttgcagcattcacattcacatcacGTCCATGCGCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaagcagcagcagcaacaacagttgggCAACAACACTGGCAACTCTTTGGTGATGGACGATGATGAGCCACCCAAGTTGATTATTGACGAGGATGACGAGGATGTGGAGGGAgaggacgatgaggatgaggaggaggagcaggaatTTGATGTCGATGAGGATGAGCAGGAGGATGAAGAGATGGACTTGGACGatgagcaccagcagcagccgcacgaggaggatgacgatgacgatgatgatgatattgctgatgatgttgcagcagcagcaacagaggcgtcgcagcaacaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAGCAGCCGCATACTCAAACAGAGTCCCTGAGCGGCAATAAGCCGGcggcgccaacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTTGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCATATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGTAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACGTGAACTGGAAatggaacgggaacgggagcGGGAACAGCAACATTTGATCCAACAGTATCGCCAACAAatggccgctgctgcagcggctgctgttgccgttgccgctgtCGCTGCACCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAGCACATTAAGCAGCTGCACGCTCACGACTTTGCACTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAactgcagcatcaacagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGATGAGGGTGCTGCTGTCGGCACCAGATCGGGCAAGTATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGCCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacacttgccagaacaacaacaacaacaataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQPQQQQSHTAAATAVAAATQEDARDLGLIETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTAPSRKRKLRQPHQQQQQLPLSDEEQQQQQLLDSSTQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNINNNISSSSSSSAVAQSAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQSTQQQQQPQSQSQQQRRQQHAGGAGATSSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNNNNNNNNKNEDELELEDEQLVLSNKQRRLKAALNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEETELEEQQQQHEEDHEQQHKQEEQEHTEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRSDADMLTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTAAATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATAATAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAATAAAMSNLSQQQQLQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQQQQQQLGNNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEDEQEDEEMDLDDEHQQQPHEEDDDDDDDDIADDVAAAATEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKASEKQPHTQTESLSGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELEMEREREREQQHLIQQYRQQMAAAAAAAVAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQHQQQQQLPMAGGAPHSDDEGAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -