Basic Information

Insect: Drosophila trichaetosa
Gene Symbol: Hr39
Assembly: GCA_035043205.1
Location: JAWNNE010000075.1:607370-610399[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.47 4.1e+03 -3.2 10.3 32 204 43 209 31 213 0.42

2 3 2 1.8e+04 -10.3 26.7 46 148 197 324 175 363 0.35

3 3 9.6e-100 8.6e-96 321.8 13.2 1 408 496 885 496 885 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.47	4.1e+03	-3.2	10.3	32	204	43	209	31	213	0.42
2	3	2	1.8e+04	-10.3	26.7	46	148	197	324	175	363	0.35
3	3	9.6e-100	8.6e-96	321.8	13.2	1	408	496	885	496	885	0.84

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAAAACATGTCGACGGCGACAGTGACGCCAgcgttgcagcagcatcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcataGCGGCAGCTTGCGCATTTCCCTCGGTGGCAATGGGGATGAGTCCGATTCGGATGCGGAGCTGGCGAACATTGAGAATCTAAAGGTGCGACGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAATGAAACGAATGGCGGCGCCGTCGGCGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcagcagcagcagtgccacaACGATGGCCAGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGGgagatgcaacaacagcaacagcagcagcaacaacagcaacaacagcagcagcagcaacaacagcagcaacaacagcagcagcagcaactgcaacagcaacaacttcaactgcaacaacaacaattgctgccacTGAAGCAACAGAGCTATGCACCGAACAACAAGCTAAAACTAGCGCCAACGCAAAGTGATCccatcaatttgaaatatgagccaacgacaacgacaacatcgtCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccactgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTACACGCCCTCGCTGAGCAGAAACAACAGCGATGCGTcgcacagcagctgctacagctacagctccGAATTCAGTCCCACCCACTCACCGATTCAGGCGCGACATGCGCCACCCGCTGGCGTTGCTGCCTTGTTTGCCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTGAGCATGGATGGTGCGGGTGGTGCAGCGTTGGATGCCAGTGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTAATCAATTCGCCGTGTCCGATTTGTGGGGACAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAaaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGTCCCGCCTGCCGTTTCGAGAAGTGTCTGCAGAAGGGCATGAAATTGGAGGCGATTCGCGAGGATCGCACCCGAGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCggcagccgctgcagctgccgcagccgttgtcaatcagcagcagcagcatcagcaacaccaacagcagcgacttcaacagcatcagcagcagcaacaacagcagcaacagcagcagcagcaacacggCCCACTCAATGGCTTTGGTGGTGGCTCCAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAAGCGGAGCAGCTTAATCATCATACGTTATCTTCAGCGCGAGCCTCAAGCATTCCAGCCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAGTATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCATCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCAGACGGGCAATGCGCAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGATCTGATCGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGATACGCCCGGCGAGATCAAGATGTCGCAGGGCAGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATTGAGCGCATGTTGAATCTGACGGATCATTTGCGACGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAATTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGCcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGTGcagatttcaatttgctgatgGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATVTPALQQHQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRISLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQLQLQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFAGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDGAGGAALDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQHQQHQQQRLQQHQQQQQQQQQQQQQHGPLNGFGGGSNSLPASPSLGGASIKTEQAEQLNHHTLSSARASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQQTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00609932;