Basic Information

Insect: Drosophila triauraria
Gene Symbol: ZNF296
Assembly: GCA_014170255.2
Location: CM024337.1:28756702-28761182[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0016 0.12 12.8 1.5 1 23 162 184 162 184 0.96

2 25 1.5 1.1e+02 3.5 3.7 1 21 191 211 191 213 0.84

3 25 0.021 1.6 9.3 0.4 2 23 245 266 244 266 0.95

4 25 0.00032 0.025 15.0 0.9 1 23 339 362 339 362 0.94

5 25 1.1 87 3.9 0.5 1 20 403 422 403 424 0.92

6 25 0.012 0.96 10.0 0.1 2 23 437 458 436 458 0.96

7 25 0.0035 0.27 11.8 1.3 1 23 539 562 539 562 0.96

8 25 0.0091 0.7 10.4 0.3 2 22 572 592 571 592 0.93

9 25 0.26 20 5.9 6.8 1 23 601 623 601 624 0.94

10 25 0.0016 0.12 12.8 1.5 2 23 639 660 638 660 0.97

11 25 1.5e-05 0.0011 19.2 4.3 1 23 667 689 667 689 0.98

12 25 0.012 0.95 10.0 4.1 1 23 827 850 827 850 0.97

13 25 0.021 1.6 9.3 1.2 1 22 857 878 857 878 0.95

14 25 0.021 1.6 9.3 1.4 1 23 887 910 887 910 0.93

15 25 7.8e-05 0.006 17.0 2.3 2 23 929 950 928 950 0.97

16 25 8e-05 0.0062 16.9 0.4 1 23 957 979 957 979 0.98

17 25 0.029 2.2 8.9 0.0 2 21 1006 1025 1005 1026 0.92

18 25 0.0021 0.16 12.4 3.0 1 23 1072 1095 1072 1095 0.97

19 25 0.013 0.99 10.0 0.6 1 23 1132 1155 1132 1155 0.96

20 25 0.00025 0.019 15.4 1.5 1 23 1183 1206 1183 1206 0.97

21 25 4.7e-06 0.00036 20.8 0.2 2 23 1233 1254 1232 1254 0.95

22 25 0.00063 0.048 14.1 3.0 1 23 1260 1282 1260 1282 0.99

23 25 1.9e-06 0.00014 22.1 2.0 1 23 1288 1310 1288 1310 0.98

24 25 1.6e-07 1.3e-05 25.4 2.4 1 23 1316 1338 1316 1338 0.99

25 25 0.0011 0.085 13.3 0.1 1 21 1344 1364 1344 1368 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0016	0.12	12.8	1.5	1	23	162	184	162	184	0.96
2	25	1.5	1.1e+02	3.5	3.7	1	21	191	211	191	213	0.84
3	25	0.021	1.6	9.3	0.4	2	23	245	266	244	266	0.95
4	25	0.00032	0.025	15.0	0.9	1	23	339	362	339	362	0.94
5	25	1.1	87	3.9	0.5	1	20	403	422	403	424	0.92
6	25	0.012	0.96	10.0	0.1	2	23	437	458	436	458	0.96
7	25	0.0035	0.27	11.8	1.3	1	23	539	562	539	562	0.96
8	25	0.0091	0.7	10.4	0.3	2	22	572	592	571	592	0.93
9	25	0.26	20	5.9	6.8	1	23	601	623	601	624	0.94
10	25	0.0016	0.12	12.8	1.5	2	23	639	660	638	660	0.97
11	25	1.5e-05	0.0011	19.2	4.3	1	23	667	689	667	689	0.98
12	25	0.012	0.95	10.0	4.1	1	23	827	850	827	850	0.97
13	25	0.021	1.6	9.3	1.2	1	22	857	878	857	878	0.95
14	25	0.021	1.6	9.3	1.4	1	23	887	910	887	910	0.93
15	25	7.8e-05	0.006	17.0	2.3	2	23	929	950	928	950	0.97
16	25	8e-05	0.0062	16.9	0.4	1	23	957	979	957	979	0.98
17	25	0.029	2.2	8.9	0.0	2	21	1006	1025	1005	1026	0.92
18	25	0.0021	0.16	12.4	3.0	1	23	1072	1095	1072	1095	0.97
19	25	0.013	0.99	10.0	0.6	1	23	1132	1155	1132	1155	0.96
20	25	0.00025	0.019	15.4	1.5	1	23	1183	1206	1183	1206	0.97
21	25	4.7e-06	0.00036	20.8	0.2	2	23	1233	1254	1232	1254	0.95
22	25	0.00063	0.048	14.1	3.0	1	23	1260	1282	1260	1282	0.99
23	25	1.9e-06	0.00014	22.1	2.0	1	23	1288	1310	1288	1310	0.98
24	25	1.6e-07	1.3e-05	25.4	2.4	1	23	1316	1338	1316	1338	0.99
25	25	0.0011	0.085	13.3	0.1	1	21	1344	1364	1344	1368	0.91

Sequence Information

Coding Sequence: ATGCTACCACCGAATATCTGCCGCACTTGTGCGCTTCAGAACACGGATTTGCGGCCATTTGCCTATGCCTTTGTGGAGCAGGCCAGAAAGGTCAATGGAGAGCTGTTGGTTCGCTTGCGGGAATGCCTGGACGAAATGCCCATTGATATTCCGCAGGAGCAGCAGCAAATCAAGACCGAAGTAGACATCGATGAAACGACTCCCAAGTGTGATGTGGATGTGGATTCCACCGGAATATCGCCTGTGGAGTTTAAATGGCAGCCGGAAAGTGGCAGCGATGAAGAATCTGGTGGAGCCGCAGCCAATGACGAGAATGAGGTCGAGATGAAGCCCTATTCCCTGCGACGTAGCGCGAGGAAAATCAAGCAGCCAGTGGAGAGCGATAATGAGGACTTAATTCCCACGGAACCATCGCCCACCAAACGTCGTCGTGGACGTCCTCCCGGCCCGGCTAAGCGCCAGTCGATGACATCCGACGGACGCCACGCCTGCAAGGTGTGTGGCAAGACCTTTTCCTGGTTCCGTGATATGCAACGCCATGCCCGCATCCATTACGAGAAATCCAATGCCTACGTATGCGATACATGTGGCAAGGGATTTCTGCGCAAGGACAAGTACACATTCCATTTACGCTGCCACGAAAAGCGCGATGCCAAAGGGAAGGCTCTGCAGCTGGGGAGCGAGTGGCGCTTCGCCGAACGACTGTACAGTTCCGGCAGGCTGAAGAGGATTGAGTGTAAGCTGTGTGGCTTGAAGTGTCCAAGAATTCAGGAGCTAAGAATTCACCTGGTCAGTCATCGGAACGTGGAGAGTCTGCTTCAGTTGACGGCGAATAGCGATGTGATCAGGGAGCACTACGCTGACCAGCCCAGCGACTTGGACGGCGTGAAACAACAAATTATCGTGGACATTGCGGCAGGACACATTGATAAGTTTGCCTCCGTGGTGAATTTCTATGGCTATGAGCTGGGATTGTATGACTCGGACGAGGAATCGGCCAGCGAAGAGTCCAAATATGAGTGTACGGTGTGTAATCTTCCCTTCTCCCGGAAACATCAAGTGGTGAGGCACACGCTGGAGGAGCACGCACAGTCCTCCCCCTCAGAGCTTCCCTGGCAACGCTGCAGTTTCTGTAAAATTGGATTCCTCTGCTCCAGACTCTACGATTGCCATGTCAGCACGCAGTGTCAGAGCAAACGGAAGCGCCATAGCTGCCCAAGGTGCCCAGGAAAGTTTATGTGGCCGGAAAATCTGCAGAGGCACGCCTGCTTAAATCGGAACGAGGAAGCCACGCTTGTCCGCCACATCTCCTGCTCCTTGTGCGATGAGTCGCTGCCCACCTTGGCCAAGCTGCGTATCCACCTGGTTACCCACCAAACTGACCTGTGTGGTATCGATCCGGAGCACACCTCCACGTTCTTTCAGTCGTTCCACCCCAACGGATTGGACTGCACTCCGGAGGAGCTGGGTGTTCGCATAGCTGAAGACTTCGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAGGAGCTGGATCTCTTTGACTCCGAGACCGAGCAGAGCGGCGATGAGCAGGAGGAGCGTGAGAAACCCGTCTCGCATACCTGTCTGCTGTGTGGAAAGGTGACGAACAGACTCCTGACCCTGATGCAGCACCAGAACAGCGACCACACAAAGGCGGCGACAGAGTTGCTATGCTCCTGCCAGGATTGTGGTGCTGGCTTTATCAGTGACGCCCTGCTCCAACAGCATCGCCGCCGTGTCTGCGCCAAGAAGCACTTCCGCCATCACTGCCAGAGCTGTAATCTGCGGTTCGTGTGGTCGAGTAATTACGAGCAGCATTTGAGGACCCACCACAACCAGGCTCCAGAGGAGGAGCAACCGGAGGAGGGCAAACTGCAATGCGACGACTGTGAGAAGGTCTTCATCTGGCACAAGGATCTCACTCGTCACAAACGATTGCACCAGCCGCAGTCGGCGCAGTTCGAGTGTCCCCATTGCGAGCGCAAGTTCCACCGCAAGGATGGATTAAAGTCCCACCTGCGGGTGCATTCAGAGGAGCAGCTGGTGGAGCAGCAGCCTCTCACATCCGACAGTGATCAGGTTCTGGCCCTGCTGATTCGTCCTCATGGCTGCAAGCAGATCCAGTGCATGATCTGCCTCTCACGACACGCCAAGATCTCTGATCTCCGAATTCACCTGACCTCCCATCAATACGGATTGAGCTTCTCTCCCGAGGCCGACAGTTCCAGTGTCTCGAAGTCGCTGTATCCGGAACTGGGCACTGCCTTAGACAGTGACGAGCTGGCGGAGAGGATTATGGCTGATGTCGACAAGGGACTGGAGCTGGATCGATTCATTTCCATTACGAACGAAGCTGGCCTCGAACTGAACTTGGATAGCAGCGAAACGGACACTGAATCCGAGCCAGAGACAGAGGAGGAAGACCAATCTAGCCATAACTACTCCTGCTGTCTCTGCCCCACGGAGGTGAAGAGAAAGCACCAACTCTATGCCCACCAACGGGAGACTCATCGGTGGGAGGATGCACCTTTCGTTTGCTCGCACTGCCAGGGTAGGTTCGTCAACGAGTCCCTGCTAGATCACCACTCCAGGACCCTTTGCGGCAATGCCCAGAAGCGCTTCCAGTGTCGCAAGTGTCCACTTCGCTTCCGCTGGCGCGAGAACCTGAAGCTCCACCTGTACCTGTCCCATCAGCAGGCTGAGATGCCAGCTGCAGAGGACTCGCCGCAGGCGGAGGCCGAACTGCAGTGCAGAGAGTGCCAGCGAACGTTCAAGATGCAGAAGGATCTCACTCGGCACACGCTGATGCACGCCCGGGAGGCGACGATCTACCGGTGCCGCTGGTGTGCCCGCCGATTCTACCGTTGGGCCAATCTCCTGCAGCACATCGCGCGCCACGGCATCCGGGCTAGCCAGTTGCACTACGCCGAGGCTCTCCTGGACTCCTACGGAAATCCAGGCGGGCGGAAGACGGTGGTGTGTCGTGTGTGCAATGTTAGCTTCTCCAGCATCGCTGCCCTGCGTCTGCATCTGGAGACCACGCCGGCCGGCAGTCACCACGAGCTCTCCTCGTTGAAGAACTACTCGATCACCAACCAAATGGGTTTCGAGCTGGATCTCCAGGACTCGGAAACGGATGAGGAGCAGTCGAAGCCTCCCGGGGTGCCTGCCTATTACACGTGTGGCATGTGCCAGTTGAGGTGTGTGCGGAAGTTCGAGCTGCAGCAGCACCAGCAGTCCATGCACCGGCTGGAGAAGATTCCCGACGGCTGTGATCAGTGCATCTTTAAGAGCGTCTGTCCCGATTTCATTGCCCACCACAAGAGGACGCAGTGCGGCAATCGGGAGAAGCAGTTCACCTGCGTTCGCTGCGGCTACAAGTTCATGTGGGAGTCGAATCTGCTCACGCACATGCAGCTGCAGCACGGAAAGATCGACAATCTGGAGCCGGAGGAGAGCAAAGAGGCTTCGGCGGAGGAACCGGCCGAAAAGGCCGGTTGCCCAGTCTTCCAGTGTGGCCTCTGCCCCAGGAAGTATAACCGAAAGGATCGCCTGACGGCGCACGTGAAGAAGTTCCATGGGCCCGATGGCAGGGGCCCCGAGGTGGTAAAGGTTCCTCCTAACAGACCCACCTCGCCCAAGGAACCGAAGCGCTTCCTGTGCGCTTTCTGCGGCAAGGCGGTCAGCTCCTCCTCCAACCTGATCATCCACATGCGCCGCCATACCGGCGAAAAGCCTTTCAAGTGTGAGTTCTGCGAGATGGCCTTCCCCCGATCCTCGGACCTCCAGTGCCACCGACGAACCCACACTGGAGAGCGGCCGCACGTTTGCACCGTTTGCCAGAAGGGATTCGCCCGGTCCTACAAGCTGCAGCAGCACATGCGCATCCACAGCGGCGAGCGGCCGTACAAGTGCACCTACTGCGAGAAGAGCTTCACGCAGTCCAACGACCTAACGCTCCACATCCGTCGACACACGGGCGAGCGGCCCTACCAATGCGGCGTCTGCGGCGAACGCTTCATCCAGGGAACGGCGCTGAAGAATCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGAATTCGGGGGAGCCTACAAGGCGCACGGTCTTAGAGCAGTTTACTGTATGA
Protein Sequence: MLPPNICRTCALQNTDLRPFAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQQQIKTEVDIDETTPKCDVDVDSTGISPVEFKWQPESGSDEESGGAAANDENEVEMKPYSLRRSARKIKQPVESDNEDLIPTEPSPTKRRRGRPPGPAKRQSMTSDGRHACKVCGKTFSWFRDMQRHARIHYEKSNAYVCDTCGKGFLRKDKYTFHLRCHEKRDAKGKALQLGSEWRFAERLYSSGRLKRIECKLCGLKCPRIQELRIHLVSHRNVESLLQLTANSDVIREHYADQPSDLDGVKQQIIVDIAAGHIDKFASVVNFYGYELGLYDSDEESASEESKYECTVCNLPFSRKHQVVRHTLEEHAQSSPSELPWQRCSFCKIGFLCSRLYDCHVSTQCQSKRKRHSCPRCPGKFMWPENLQRHACLNRNEEATLVRHISCSLCDESLPTLAKLRIHLVTHQTDLCGIDPEHTSTFFQSFHPNGLDCTPEELGVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDEQEEREKPVSHTCLLCGKVTNRLLTLMQHQNSDHTKAATELLCSCQDCGAGFISDALLQQHRRRVCAKKHFRHHCQSCNLRFVWSSNYEQHLRTHHNQAPEEEQPEEGKLQCDDCEKVFIWHKDLTRHKRLHQPQSAQFECPHCERKFHRKDGLKSHLRVHSEEQLVEQQPLTSDSDQVLALLIRPHGCKQIQCMICLSRHAKISDLRIHLTSHQYGLSFSPEADSSSVSKSLYPELGTALDSDELAERIMADVDKGLELDRFISITNEAGLELNLDSSETDTESEPETEEEDQSSHNYSCCLCPTEVKRKHQLYAHQRETHRWEDAPFVCSHCQGRFVNESLLDHHSRTLCGNAQKRFQCRKCPLRFRWRENLKLHLYLSHQQAEMPAAEDSPQAEAELQCRECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASQLHYAEALLDSYGNPGGRKTVVCRVCNVSFSSIAALRLHLETTPAGSHHELSSLKNYSITNQMGFELDLQDSETDEEQSKPPGVPAYYTCGMCQLRCVRKFELQQHQQSMHRLEKIPDGCDQCIFKSVCPDFIAHHKRTQCGNREKQFTCVRCGYKFMWESNLLTHMQLQHGKIDNLEPEESKEASAEEPAEKAGCPVFQCGLCPRKYNRKDRLTAHVKKFHGPDGRGPEVVKVPPNRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCEMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYEEGQNSGEPTRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00483114;
80% Identity: -