Basic Information

Insect: Drosophila testacea
Gene Symbol: -
Assembly: GCA_035043265.1
Location: JAWNND010000755.1:2298286-2302914[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0017 0.13 13.0 2.0 1 23 220 242 220 242 0.96

2 25 0.12 9 7.2 2.3 1 23 248 270 248 270 0.97

3 25 0.026 2 9.3 0.9 2 23 302 323 301 323 0.97

4 25 0.0039 0.3 11.9 1.3 1 23 398 421 398 421 0.93

5 25 0.96 73 4.3 0.4 1 20 462 481 462 483 0.92

6 25 0.11 8.1 7.3 0.3 2 23 501 522 500 522 0.96

7 25 0.01 0.79 10.5 1.9 3 23 600 620 598 621 0.93

8 25 0.087 6.6 7.6 0.1 1 22 630 651 630 651 0.95

9 25 0.053 4 8.3 5.2 1 23 660 683 660 683 0.95

10 25 5.9e-05 0.0045 17.6 0.3 2 23 710 731 709 731 0.97

11 25 2.6e-06 0.0002 21.9 3.7 1 23 739 761 739 761 0.98

12 25 0.007 0.53 11.1 0.6 1 23 912 935 912 935 0.95

13 25 0.025 1.9 9.3 1.4 1 22 942 963 942 963 0.95

14 25 0.23 17 6.3 0.4 1 23 972 995 972 995 0.89

15 25 1.2e-05 0.00089 19.8 2.4 1 23 1020 1042 1020 1042 0.98

16 25 0.0012 0.09 13.5 0.8 1 23 1049 1071 1049 1071 0.98

17 25 0.0052 0.4 11.5 0.1 2 20 1098 1116 1097 1118 0.93

18 25 0.013 1 10.2 3.9 1 23 1163 1186 1163 1186 0.96

19 25 0.054 4.1 8.3 0.4 1 23 1223 1246 1223 1246 0.96

20 25 0.001 0.077 13.7 3.5 1 23 1271 1294 1271 1294 0.97

21 25 1.4e-05 0.0011 19.5 0.1 2 23 1321 1342 1320 1342 0.95

22 25 4.9e-05 0.0037 17.9 2.9 1 23 1348 1370 1348 1370 0.99

23 25 2.4e-06 0.00018 22.0 2.0 1 23 1376 1398 1376 1398 0.97

24 25 6.1e-08 4.7e-06 27.0 2.4 1 23 1404 1426 1404 1426 0.99

25 25 0.0012 0.09 13.5 0.2 1 21 1432 1452 1432 1456 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0017	0.13	13.0	2.0	1	23	220	242	220	242	0.96
2	25	0.12	9	7.2	2.3	1	23	248	270	248	270	0.97
3	25	0.026	2	9.3	0.9	2	23	302	323	301	323	0.97
4	25	0.0039	0.3	11.9	1.3	1	23	398	421	398	421	0.93
5	25	0.96	73	4.3	0.4	1	20	462	481	462	483	0.92
6	25	0.11	8.1	7.3	0.3	2	23	501	522	500	522	0.96
7	25	0.01	0.79	10.5	1.9	3	23	600	620	598	621	0.93
8	25	0.087	6.6	7.6	0.1	1	22	630	651	630	651	0.95
9	25	0.053	4	8.3	5.2	1	23	660	683	660	683	0.95
10	25	5.9e-05	0.0045	17.6	0.3	2	23	710	731	709	731	0.97
11	25	2.6e-06	0.0002	21.9	3.7	1	23	739	761	739	761	0.98
12	25	0.007	0.53	11.1	0.6	1	23	912	935	912	935	0.95
13	25	0.025	1.9	9.3	1.4	1	22	942	963	942	963	0.95
14	25	0.23	17	6.3	0.4	1	23	972	995	972	995	0.89
15	25	1.2e-05	0.00089	19.8	2.4	1	23	1020	1042	1020	1042	0.98
16	25	0.0012	0.09	13.5	0.8	1	23	1049	1071	1049	1071	0.98
17	25	0.0052	0.4	11.5	0.1	2	20	1098	1116	1097	1118	0.93
18	25	0.013	1	10.2	3.9	1	23	1163	1186	1163	1186	0.96
19	25	0.054	4.1	8.3	0.4	1	23	1223	1246	1223	1246	0.96
20	25	0.001	0.077	13.7	3.5	1	23	1271	1294	1271	1294	0.97
21	25	1.4e-05	0.0011	19.5	0.1	2	23	1321	1342	1320	1342	0.95
22	25	4.9e-05	0.0037	17.9	2.9	1	23	1348	1370	1348	1370	0.99
23	25	2.4e-06	0.00018	22.0	2.0	1	23	1376	1398	1376	1398	0.97
24	25	6.1e-08	4.7e-06	27.0	2.4	1	23	1404	1426	1404	1426	0.99
25	25	0.0012	0.09	13.5	0.2	1	21	1432	1452	1432	1456	0.92

Sequence Information

Coding Sequence: ATGTGCAGCGTGCTCTCAGGACATGGAAGGCCGGGAGTTGTGCCTGATATTTGCCGCACGTGTGCGCTACATGATGTAAATATGTTGGCGCTCTCGACGCGCAACGAGAAACACTCGAACAAAAGTTTATGTGACATGTTGCATGAATTAACACAAAGCGATcCTTTAATGGAAGATTGCGATGATAATCTGCCGCAGTATTTGTGTGGCGACTGTTTGCCTAAGCTGGAAGATGCCTATGCATTTGTGTTGCAAGCCCGGAAGGTGCAAGAGCAACTGTTGCACAAAATGCGCAAGGGGCTGGAGTGTCTGGATGAAACACCTATAGACATAGCCACGCAGCAAATAAAGACAGAGGAAGACATTGCCTTGGAGTCCACCCAAGACctcgatgatgatgatgttccAACTGTGTCTGTGGCAGCCTTAAAGATGCAACCGGAGAGTGAGACAGATAGTAGCCAAGTCACCGTGGCTAAcgAAGATGAAATAGACATAGAACCCAAACAGCCGAGACGCAGCCATCGCAAGGCAAAACTTGCTACAGACAGCGAAAATGAAGCGAGCTCTGAAATCTCAAATCCAGTGCCGCTCAAGCGTCGTCGCGGTCGTCCTGCGCGTATTCCCAAAAAGGAAACTATCAACAAGGATGGACGACATGCCTGTGAGGTGTGTGGCAAGACGTTTTCGTGGCATCGCGACATGCAACGCCACGCTCGCGTACACTTTGAGCAGGCTGGCTTCGTGTGTGACAGCTGTGGCAAGAGATTCCTTCGGAAAGACAAGTACATGTTCCATTTGCGATCACACGATAAGCGCCAGGCCAAACAAGAGGCCCTCCAGCTGGGCAAAGAGTGGCGCTTTGCGGAACGTCTCTACAGTTCAGGCCGCCTCAAGCGTCTCGAGTGTAAATTGTGCGGATTAAAGTGCCAGCGAATTCAGGAACTTCGTGAACATCTGGCTACTCATGTCAGTATTGAATCATTGGCGAACCTCAGAGCCAATAGCGATGTTATCGTGGAACAGTTTTCCAGCCAGCAGTTGGACTTGATGCAGATTAAGCAACAGGTGTGTGCAGACATAGCCAAGGGCAGAGAAAATCTGGACAAATACTATGCTGTGGTCAATGCTCATGGCTATGAGCTCTGCCTGAGTGACTCTGATGAAGAGCTAGCTGGAAAGCCGCCTCCATATCAATGCTTGCCTTGCAACACTTCCTTCTCACGCAAATACCGCCTAATGCGACATACGCTGGAGGAGCACACTCAACCGACAACTGAGACAACTTCTTGGCACCGTTGCAACCATTGCCAAATtggatttgtgtgtgtaaaactGTTGGACCAACATCAACGCACACAGTGTCACAATCAGTTGAAACGTTATAGTTGCCCCAACTGTCCAGGCAAATTTATTTGGATGCAGAATCTAAAGCGCCATGCGTGCTCCCAGCGATCTTCAGTGGCACATGATCAGGAGAGAAGTCAAAGTCGCCAAATACAGTGCTGTCTTTGCGATGAGCAGCTGCCAAGTATGTCAGCATTACGTGCTCATTTAGTAAAACATAGCGATGGACAAAGCGGCATTGATCCGGAAAGACATGCTACCTTCTTTCGCTGTAATTATCCTGATGGTTTTACCTGCAACCCGTTGGAGCTGAGCACACGTATTGCGAGTGACTTTGCCGCACAGGATTATGGAAGGTATTTCAATGCCTGCACAGACAGCGGACAGGAGTTGGATTTCTTTGACTCTGATACGGATTTAAGTGATTCTTTAGACTCAACAGTGCATTTGTGTGCTCTGTGTGGCATGAGCACAAAGCGCCTTGCCCAACTCCTGTGGCATCAACAAAATCATCACAGTGAGGTGAAGGACACATTGCCTCATGTGTGTGATAAGTGTGGAGTGGGATATGTGGCAGATTCGTTGCTCCAACAGCATCGCCGGCGGATCTGTAACAAGCGACATGCTAAATTTCATTGTGAGCATTGCAATCTTCACTTTATCTGGCAGTCCAACTACGAGCGACACATGGAACTCCAGCATGAATCGGAGACAGAAGATGTCACCGAGCATATGCCCAATACCAGGCTAAGAAGCAAACGTCATGAAGCTGCCAAACTACAGTGCAATGAGTGTGACAAGgTGTTCATCTGGCCAAAGGATCTGACGCGTCACAAGCGCATTCACCAGCCGCAAGCATTGGCACAATTTGAATGCAGCTACTGCGATCGGAAGTTCCATCGCAAGGATGGCCTCAAGTCCCATATGCGTGTGCATGGCGAGCAGCATTTGGACTTGACAATTATGTCTAACAACGATGTGCCGGATCCGTCAATGTTACAGCGGATGCCAATGGTGTTGACGCAATTGTGTCAACCGAATGGATGTAAGCAGATTCAATGCATGATCTGTCTCTCTCAGCATTCGAAGATCTCTGATCTGCAAACGCATTTGATGAAGCACCAGTTTGTTGTGGAGTTTGCAGAGGAACGTGCCAAGCCGGAGAGCATTGCGAGTATTTGCCGAGCCCTATATCCGGAGCAGGTGACTCCGCTGGATAAGCAACAACTGATTGAGCGCATCCAGAGAGATGTGGCTAACGGAATTGAGTTGGAAAGATTCATATCGATAACCAACGAGGCGGGAATTGAGCTTAGTCTGGACAGCAGCGAAACTGACACGGATTCGGACTCAGCCGAAGTGGAAGGGAGCAGCAACGGACGACAATACAATTGCGATCTTTGCCAGTTGAAGCTGTCGCGTAAATATGAACTCTATGCACATCAGCTGGAGCAGCATACATGGCAGCAGGCAACCTTTATTTGCAGCCACTGTCAGGCGAGATTCATCAATGATCAATTGCTGGAGCATCACTATCGTTCGCTCTGCCGCAATGCCCACAAGCGTTTCCTCTGTCGGAAGTGTCCATTACGCTTCCGCTGGCGTGAGAATCTCAAGTTGCACACGGGTGTGGCGCACCAAGATGGAACTGGAGAACAGACAAGCTTGGGCATACAATTGAATACGGCAAGTCTCCTTCCTGTTAGCAGCTATAATTGCACCGAATGTAATCGCAGCTTTAAGATGCAAAAGGATCTCACACGACACACACTGATGCATGCCCAGGAGTCGAGCATTTATCGGTGTCGTTGGTGTGCTCGTCGCTTCTATCGCATGGCTAATCTCCTGCAGCATATTGAGCGTCATGGCATCAATGCCTCACAGCTGCCTTATGCCGAGTCCCTGCTCAATGCCAGCCGTCATCCTCATGGCCGGAAGAGCATTCAATGCAAGGTGTGCAATATAAGTTTTCCCACAATTGCCACACTACGTTCCCATTTGACGTCCACGGCGAGAGGGACACATCATGATATTGGATCGATGCTCAACTATTCTATTACCAATCAATTGGGCTATGAGTTGCACTTGGATGACTCGGAAACGGATGAGGAGGCCAAGCCACCTGGGATTCCCACACACTACACCTGCGGCATGTGTCAACTGCGCTGTGTGCGTAAATATGAGCtccatcagcatcagcaggcTATGCATCGATTAGAACGGATTACCGATCAGTGTGATCAGTGCATCTATAAGAGCGTTTCTCCTGATCTTATCGCCTATCATCAGCGTGTGCAATGTTGCAATACggaaaaacaattcaaatgcGTTAATTGTGGCTTCAAGTTCATGTGGGAGTCGAATCTGTTGCTGCACATTCAGTTGCAGCATCCTAGCAATAATAATCAGGAGGAAGCGTCATCGGTGCCTGCAACCGAGCCATCTACAACAGAGTGCCAGATCTTTCAGTGCGGTCAGTGTCCTCGGAAATACAATCGAAAGGATCGACTGACAGCCCATGTAAAGAAGTGTCATGCACCAGGTGCAGTTGGTCCAACTGCGAGTCCAAAAACTACGACACCTTCAACTGTTGCCAAACAACAGAAGAGTTTCCTCTGCGCCTTCTGTGGCAAGGCGGTGAGCTCCTCCTCCAATCTCATTATACACATACGTCGTCATACGGGCGAGAAGCCTTTTAAGTGTGATTATTGTGACATGGCATTTCCCCGCTCCTCCGATCTACAGTGTCATCGACGCACGCACACTGGCGAACGACCGCATGTCTGCACCGTGTGCCAAAAGGGATTCGCCCGCTCCTATAAGCTGCAGCAACACATGCGCATTCATAATGGCGAACGTCCCTACAAGTGTACCTATTGTGACAAAAGCTTCACCCAGTCAAATGATCTGACGCTCCACATTCGACGTCACACTGGCGAGCGACCTTATCAGTGTGATACTTGCGGGGAACGCTTCATTCAGGGCACGGCACTGAAGAATCATAGAATACAGAATGGACATTTCGAGGCTGGAGATGGCCTGGCTAAAGATAACTAA
Protein Sequence: MCSVLSGHGRPGVVPDICRTCALHDVNMLALSTRNEKHSNKSLCDMLHELTQSDPLMEDCDDNLPQYLCGDCLPKLEDAYAFVLQARKVQEQLLHKMRKGLECLDETPIDIATQQIKTEEDIALESTQDLDDDDVPTVSVAALKMQPESETDSSQVTVANEDEIDIEPKQPRRSHRKAKLATDSENEASSEISNPVPLKRRRGRPARIPKKETINKDGRHACEVCGKTFSWHRDMQRHARVHFEQAGFVCDSCGKRFLRKDKYMFHLRSHDKRQAKQEALQLGKEWRFAERLYSSGRLKRLECKLCGLKCQRIQELREHLATHVSIESLANLRANSDVIVEQFSSQQLDLMQIKQQVCADIAKGRENLDKYYAVVNAHGYELCLSDSDEELAGKPPPYQCLPCNTSFSRKYRLMRHTLEEHTQPTTETTSWHRCNHCQIGFVCVKLLDQHQRTQCHNQLKRYSCPNCPGKFIWMQNLKRHACSQRSSVAHDQERSQSRQIQCCLCDEQLPSMSALRAHLVKHSDGQSGIDPERHATFFRCNYPDGFTCNPLELSTRIASDFAAQDYGRYFNACTDSGQELDFFDSDTDLSDSLDSTVHLCALCGMSTKRLAQLLWHQQNHHSEVKDTLPHVCDKCGVGYVADSLLQQHRRRICNKRHAKFHCEHCNLHFIWQSNYERHMELQHESETEDVTEHMPNTRLRSKRHEAAKLQCNECDKVFIWPKDLTRHKRIHQPQALAQFECSYCDRKFHRKDGLKSHMRVHGEQHLDLTIMSNNDVPDPSMLQRMPMVLTQLCQPNGCKQIQCMICLSQHSKISDLQTHLMKHQFVVEFAEERAKPESIASICRALYPEQVTPLDKQQLIERIQRDVANGIELERFISITNEAGIELSLDSSETDTDSDSAEVEGSSNGRQYNCDLCQLKLSRKYELYAHQLEQHTWQQATFICSHCQARFINDQLLEHHYRSLCRNAHKRFLCRKCPLRFRWRENLKLHTGVAHQDGTGEQTSLGIQLNTASLLPVSSYNCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRMANLLQHIERHGINASQLPYAESLLNASRHPHGRKSIQCKVCNISFPTIATLRSHLTSTARGTHHDIGSMLNYSITNQLGYELHLDDSETDEEAKPPGIPTHYTCGMCQLRCVRKYELHQHQQAMHRLERITDQCDQCIYKSVSPDLIAYHQRVQCCNTEKQFKCVNCGFKFMWESNLLLHIQLQHPSNNNQEEASSVPATEPSTTECQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAVGPTASPKTTTPSTVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRIQNGHFEAGDGLAKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558059;
90% Identity: iTF_00583838;
80% Identity: -