Basic Information

Insect: Drosophila tanythrix
Gene Symbol: ush
Assembly: GCA_035043275.1
Location: JAWNNC010000351.1:8803997-8809305[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.052 3.7 8.3 0.0 1 20 177 196 177 198 0.89

2 9 0.0003 0.021 15.4 0.8 1 23 253 275 253 275 0.98

3 9 0.054 3.8 8.3 1.0 2 21 325 344 325 345 0.92

4 9 0.037 2.6 8.8 3.0 2 21 706 725 705 726 0.93

5 9 0.0097 0.68 10.6 0.0 3 21 776 794 774 795 0.91

6 9 0.02 1.4 9.7 0.0 2 23 865 886 864 886 0.98

7 9 0.0041 0.29 11.8 1.3 1 23 892 914 892 914 0.99

8 9 0.0013 0.092 13.4 1.8 1 23 983 1006 983 1006 0.96

9 9 0.33 23 5.8 0.7 2 20 1116 1134 1115 1136 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.052	3.7	8.3	0.0	1	20	177	196	177	198	0.89
2	9	0.0003	0.021	15.4	0.8	1	23	253	275	253	275	0.98
3	9	0.054	3.8	8.3	1.0	2	21	325	344	325	345	0.92
4	9	0.037	2.6	8.8	3.0	2	21	706	725	705	726	0.93
5	9	0.0097	0.68	10.6	0.0	3	21	776	794	774	795	0.91
6	9	0.02	1.4	9.7	0.0	2	23	865	886	864	886	0.98
7	9	0.0041	0.29	11.8	1.3	1	23	892	914	892	914	0.99
8	9	0.0013	0.092	13.4	1.8	1	23	983	1006	983	1006	0.96
9	9	0.33	23	5.8	0.7	2	20	1116	1134	1115	1136	0.91

Sequence Information

Coding Sequence: ATGTGTGAATTCGTGAAAATCGACACTGCAATTAGGGCAACTGGCAATGGGGAGAAGTGGGCGCGcacccaacaacaacagcaacagctcgaGGATCAGGCCGAAGACGAGCAGTTAGAGCAACAGTCGAACAACTCCTCCTTGCAACCCGTCGAGACTTACATGGAACAGGAACTGGAGGAGGCACAAGCGGCAGCACAGGATTCCAGCGAACAGAAGTTGGAGGATAACCCGACAATGACAACGCCGCCGCGTAGCCCAACGCCCGAACTGGTGCCCAAGCTGGAGCGAGCTGATACGCCACCCTCAGTTCCGGTCACGCCCAGTCCACCACCGCGTACGCCCACACCGCCGCCAATTGTGCTGCCCAAACTGCGACTCAATGCGTTGCTTGCCTCCGATCCGGCATTGAAGCCCGATGCCAAGGAGCTGAATTTGCACGAGTCACGACTGCTGGGACCACCGCCCAAGCCGGAGCAGCAACCGAGCCTGCAGCCGGATGTGGAGCCGCTGTTGAAACCGGCGCGATTTATGTGCTTACCCTGCAGCATCGCTTTCAGTTCACCCTCAACGCTGGAGGCGCATCAGGCCTACTACTGCTCGCATCGCAACAAGGATGCTGAGGAGGAGACAAACGCTGCCGGTGATAAGGTGACATCCAACAGCGGTGGCACCTCCAATGCCAACAGCAGCTCCAGCGGCTCAAGTGCCACCGCCTCCGAGCCACCCAACAAGGTGTCCCGCATTGGTAAACAGTATGCGTGCACCCAGTGCTCCTACAGTGCAGACAAGAAGGTCTCCCTCAATCGACACATGCGCATGCATCAAACATCTCCAGCGGCACCCAGCCTAAACAGCCTCTCCAGCTTGACAGCAAATGGTGTTGTTGCCgcggctgctgccgccgctgcggcagctgctgctgctgctggtgcccAGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAACAGCACTACTGCAGCTCCCGTCGCAGCGACGGACAACTGACGCCCGCCGGAGGCGGGTGGCATGACTGGAAGTGGAGTTGGTGGCGCTGGAGCtgTCCACAGACGCGGAACAAGACGCCAACGCCGGCaatggttgctgctgccgccgccgcggctgcggctgctgctgcctcgctGCAGGTGGCACCACCGCAACCCTTCCTAGCGCTGCCCACCAATCCAATTATCATAGTGCCCTGCTCGCTAATACGTGCAGCCAGCTTGATACCGGGACCACTCACCACCTCTACGTCGGGCATTGTGAATCCGGAGTCCACATGCTTCACGCTCGACAATGGCGCTCTGAAGCCTCTAGCCACAGCtctaaacataaatacgctaGGGGGCAGTGCCACGCCTACGCCTATGCCTAGCAGCAATCAGATACCGATTCCCGCTTTAGAGCCAGATCGTCCAACCCCTGTGAGCATTTCAAGCAACCTGGAAACGGAACCCAAGAAAAGTTCACCAGAACCCAAGCGCAAGGAAACAAGCGGCATACGTGAGACGACACCCTTGGATTTATCGCTGAGGCGGTCGCCAATCTCTGCGCTATTGCAGCGCCAGCGTCTCGCGCGCTCTGCCGCTGCGCTGCTGGACGCCGAGGATGCTGCAGGCAAGGATGCTCACTTGGAGAGCATCAGTGGCGGCAGCGTTACACCCGAGCAAATTGTTTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGCCCCTCACCCAAGCGACGTGCTTTAAGTCCACGCAGCTCGGGAGCTGGGAGCGCTTCGTCGATGTCACCTCCAGCCCATCATATATTGGATAATTTGCCGCCGTTGCGCTCCATGCTGCCCTCCGACTTTAATCTCTCCGAATCGCTGCTGGCCAAAACGAATCCAGAGCTGGCTCTCAAactggcggcggcagcagcggctgctgtgGCAGGCGGTGGCTCGGCGGAGCTGGCCAAACTAGGATTTCCAGGAGGTGGTGCAGCAACCAGCAGTGGTGCTACTGCACCATCCTCTGCACAGAATGCACCGCAGATCTATGTGAAGCAGGGCGTCTCCAAGTGTAAGGACTGCAATATTGTATTCTGCAAATATGAGAATTATTTGGCGCACAAGCAACATTATTGTTCGGCACGCAACCAGGAGACGGGCCTGGATGGAGATGCCTCCAAGAGCGCTGTAACGCCTCCCAGTGGACTATCGTCAGTTGGCGGTAATGCTGGCGCCTCCTCTGCAGAAACCACTCCCGTTGCCTATCAGCAACTAATATGCGCCGCCTGCGGCATTAAGTACACATCGCTGGATAATTTGCGTGCACATCAGAATTATTACTGTCTAAAAGGAGgcgctgcggctgctgccacGCCAGCTGaggcagcaccagcaccacaacTGCCACTCGCCCATCCCAAGGAGAAGTGCCCGAAATGCAAGACTCATCATGAGCACGGACAGAATTGtccaccacctccaccaccgGCAACTCCACAACTGCCTGCTCCCTGCTCCACCTCTGCCACGTCGAATAGTGTCAATAAGTGTCCCGTTTGTGGCGTAATTAGTCCCACTGCTGCCCTCGCCCGCAAGCACATGGAGATGCATGGAACGGTGAAGGCTTTTCGCTGCTCCATTTGCCAGTATAAAGGGAACACTCTCCGCGGGATGCGCACCCACATTCGCACCCATTTCGATAAAAAGACCAGCGATGTGAATGAGGAGCACTACATGACATGCATCTTTGAGGAAGAtgctgcagcagtggcagcaacagttgctgctccaACTCAATCCTTGAATATAGATCTGCCCGCtgtggcagcggcggcggcggcggcggcagcagcagcagcagcagctcaagaGCAATTGGAACAGCATCCGGCACAGCTCTTCAATTGCGATCATTGCAATTATGCCTCATCCTACAAGGGCAATGTGCTGCGTCACATGAAACTACTGCATCCGCATGTGGCCATTAGTTCGCCCTCCATTTCACCCGAGTCGCGCGAACAGGAAGCCAATCCTCATGCCCTACCCGAAATATCGCTGGTTAATGGGGAACGGGAAGCAGCATCTATGCCCAGCTTCCACATTAAAACGGAGGCATTGGAGGCACCGGTGGCCACATTGAGTCTGGTGCATGAGAACAACAATTCACCCATTAGCACACCACTTACCCACATTAAAGCAGAGCCCATGGAACTTGGTGTAGATGTATCAGTACCGTCTCTACCCCCGCCGATGGCCAACTCCCCGCTTGGGCCGAGCGCAGCGGAGGCATTGAAAAAATACTGCTCCACCTGCGACATATCCTTCAACTACGTAAAGACATTTCTGGCGCACAAGCAATTCTACTGCAAGAGCAAACCACTTCGACCCGAGGCAAATGATAGCCCCAGTCCGACGGTGGGCGGTGGCGTCTCAATGCCGCTGCAGTCGCCCAgcgagctgctgttgctccagAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MCEFVKIDTAIRATGNGEKWARTQQQQQQLEDQAEDEQLEQQSNNSSLQPVETYMEQELEEAQAAAQDSSEQKLEDNPTMTTPPRSPTPELVPKLERADTPPSVPVTPSPPPRTPTPPPIVLPKLRLNALLASDPALKPDAKELNLHESRLLGPPPKPEQQPSLQPDVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKDAEEETNAAGDKVTSNSGGTSNANSSSSGSSATASEPPNKVSRIGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPSLNSLSSLTANGVVAAAAAAAAAAAAAAGAQLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPAGGGWHDWKWSWWRWSCPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINTLGGSATPTPMPSSNQIPIPALEPDRPTPVSISSNLETEPKKSSPEPKRKETSGIRETTPLDLSLRRSPISALLQRQRLARSAAALLDAEDAAGKDAHLESISGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGAGSASSMSPPAHHILDNLPPLRSMLPSDFNLSESLLAKTNPELALKLAAAAAAAVAGGGSAELAKLGFPGGGAATSSGATAPSSAQNAPQIYVKQGVSKCKDCNIVFCKYENYLAHKQHYCSARNQETGLDGDASKSAVTPPSGLSSVGGNAGASSAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCLKGGAAAAATPAEAAPAPQLPLAHPKEKCPKCKTHHEHGQNCPPPPPPATPQLPAPCSTSATSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAATVAAPTQSLNIDLPAVAAAAAAAAAAAAAAQEQLEQHPAQLFNCDHCNYASSYKGNVLRHMKLLHPHVAISSPSISPESREQEANPHALPEISLVNGEREAASMPSFHIKTEALEAPVATLSLVHENNNSPISTPLTHIKAEPMELGVDVSVPSLPPPMANSPLGPSAAEALKKYCSTCDISFNYVKTFLAHKQFYCKSKPLRPEANDSPSPTVGGGVSMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538480;
90% Identity: iTF_00570666;
80% Identity: -