Basic Information

Insect: Drosophila tanythrix
Gene Symbol: RREB1
Assembly: GCA_035043275.1
Location: JAWNNC010000508.1:4358957-4365818[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.039 2.7 8.7 0.8 1 21 274 294 274 296 0.93

2 12 0.00037 0.026 15.1 0.2 1 23 306 328 306 328 0.98

3 12 0.00027 0.019 15.5 7.2 1 23 334 356 334 356 0.98

4 12 0.96 67 4.4 1.5 2 20 590 608 590 610 0.93

5 12 0.018 1.3 9.8 0.2 1 23 754 776 754 776 0.97

6 12 7.6e-06 0.00053 20.4 1.2 1 23 786 808 786 808 0.99

7 12 0.00091 0.064 13.9 2.0 1 23 814 837 814 837 0.97

8 12 0.0032 0.23 12.1 2.0 1 23 1102 1125 1102 1125 0.95

9 12 9.4e-05 0.0066 17.0 0.3 2 23 1513 1534 1512 1534 0.97

10 12 0.16 11 6.8 6.3 1 23 1540 1563 1540 1563 0.97

11 12 0.0092 0.65 10.7 0.5 3 23 1766 1786 1764 1786 0.96

12 12 0.0015 0.1 13.2 4.8 1 23 1792 1814 1792 1814 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.039	2.7	8.7	0.8	1	21	274	294	274	296	0.93
2	12	0.00037	0.026	15.1	0.2	1	23	306	328	306	328	0.98
3	12	0.00027	0.019	15.5	7.2	1	23	334	356	334	356	0.98
4	12	0.96	67	4.4	1.5	2	20	590	608	590	610	0.93
5	12	0.018	1.3	9.8	0.2	1	23	754	776	754	776	0.97
6	12	7.6e-06	0.00053	20.4	1.2	1	23	786	808	786	808	0.99
7	12	0.00091	0.064	13.9	2.0	1	23	814	837	814	837	0.97
8	12	0.0032	0.23	12.1	2.0	1	23	1102	1125	1102	1125	0.95
9	12	9.4e-05	0.0066	17.0	0.3	2	23	1513	1534	1512	1534	0.97
10	12	0.16	11	6.8	6.3	1	23	1540	1563	1540	1563	0.97
11	12	0.0092	0.65	10.7	0.5	3	23	1766	1786	1764	1786	0.96
12	12	0.0015	0.1	13.2	4.8	1	23	1792	1814	1792	1814	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcaacaatcgcacacagcagcagcaactgcagcagcaacacaagaGGATGCTCGGGATTTGGGCTTAATGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAAAaagttgagcagcagcagtggcgcACCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTGcgacagcaacaccagcagcagcagcagcaacagttgccgctcTCCGAtgaggagcaacagcagcaacagcagcagcagctgttggaTTCGTCAGCGCAGCGACCGCGTCACAAACAGCGACGTagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCGAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTCCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGCAGTGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataacaataacaacaacaataacaacaacaatagcaacaacaataacaacaacaataacaatatcaacaacaatatcagtagtagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcgtcggcaGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAATATGCACCGACACATGCGCACCCATAAGCAACATCAGGcctcgcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcaacagcggcgcCAGCAACATGCGGGCGGAGCAGGCGCAACTGGCTCGGGATCGGGATCGGGTTCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAACagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacaacaacaacaataataataataataataacaatgagGATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATtgagcagcaaacagcgaCGCCTCAAGGCAAccctaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGATGTGGACAGCGTTGAAAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACGTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCTTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAAttggaggagcagcagcagcagcatgaggAGGACCACgaacagcagcacaagcaggaGGAACAGGAGCATGCCGAGCAGCGCGAATGTGAAGATTTCTTTCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCGGTCTTTCCCAATTTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATTCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCATACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGACCGATGCCGATATGCTAAACGAGATGAGCGGCTATCGCTGTCCTACACCCACGGAGCAAAGCTCCTCGGCTAGCTCCTCGTCACAGCTGAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTAAAGgtaacagcaacagtggcagcaacaacatcgctGCCTCAACAACCGCTCAAGATTCAAGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcaacaccaacaacagcagcaacaacaccagcaacagcagcagcagcaacaaatgttcGGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCacgccgccgccaccagcaacggcagcagcagcaacagcagcagacaagtcaatgccaacaaatccagcagcagcagccggggcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCATgtgaagcagcagcatccacagTTCTATGCGTTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagctgccgcagcaaTGAATAATctcagccagcagcaacagttgcagcagcagcagcaacagttgcagcattcacattcacatcaCGTCCATGCGCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaagcagcatcagcaacaacagttgggCAACAACACTGGCAACTCTTTGGTGATGGACGATGATGAGCCGCCCAAGCTGATTATTGACGAGGATGACGAGGATGTGGAGGGAGaggacgatgaggatgaggaggaggagcaggaatTTGATGTCgatgaggaggagcaggaggatgAAGAGATGGACTTGGACGAtgagcatcagcagcagccgcacgaggaagatgacgatgacgatgatgatgatgctgctgccgcagcagcagcagcagcagcagcagcaactgaggcatcgcaacaacaattgcagccaaCAAAGGACAAACTTCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCGAGAAGCAGCCGCATACTCAAGCGGAGTCCCTGGGCGGCAATAAGCCGGcgacgccaacaacaatgaaaacaatgatTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAAGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTAGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTTGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCTGGCACCGAGGATgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACACACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCGGTCGAGGAGATTGAGCTTGAGGAGCAGCGACGTCGCCAGGCGGCCGAGGCCGAACAGGCCGAGCGAGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacgggaacgggagcGGGAACAGCAACATTTGATACAACAGTATCGCCAACAAAtggccgctgctgcagcggctgctgctgccgttgccgctgTCGCTGCACCAGCGCATCCAACACCACCACAACCAGCCCAATCGCCACCGGGCCTGGAAGCGAGCAGTGATCTGCCCTACAAATGCCATCTTTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCACTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAAgtgcagcatcaacagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGATGAGGCTGCTGCCGTCGGCACCAGATCGGGCAAATATCCCGACTACAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGCCGACATATGCGCACTCATTCCGGTGAGCGGCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacacttgccagaacaacaacaataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCAAAAGGAGAACATTGccgaggcaacaacaacgccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagctgtagccAGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQSHTAAATAAATQEDARDLGLMETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHQQQQQQQLPLSDEEQQQQQQQQLLDSSAQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNNNNNNNNNSNNNNNNNNNINNNISSSSSSSAVAQSAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQSTQQQQQPQSQSQQQQQRRQQHAGGAGATGSGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNNNNNNNNNNNNEDELELEDEQLVLSSKQRRLKATLNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYSVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTDADMLNEMSGYRCPTPTEQSSSASSSSQLKHMLLAEPTPAVKVTATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQHQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATAAAATAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAAAAAAMNNLSQQQQLQQQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQHQQQQLGNNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQPHEEDDDDDDDDAAAAAAAAAAAATEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKAEKQPHTQAESLGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQHLIQQYRQQMAAAAAAAAAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQVQHQQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNTCQNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEQKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -