Basic Information

Insect: Drosophila takahashii
Gene Symbol: su(Hw)
Assembly: GCA_018152695.1
Location: JAECXN010000119.1:417505-421613[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00083 0.051 13.8 1.9 1 20 214 233 214 235 0.94

2 12 2.6e-06 0.00016 21.7 0.4 3 23 286 307 284 307 0.93

3 12 0.25 15 6.1 0.0 1 23 313 335 313 335 0.94

4 12 5.1e-07 3.2e-05 23.9 2.4 1 21 342 362 342 363 0.95

5 12 5.8e-06 0.00036 20.6 1.0 2 23 375 396 374 396 0.96

6 12 0.00026 0.016 15.4 6.3 1 23 407 429 407 429 0.99

7 12 7.6e-05 0.0047 17.1 0.9 1 23 435 457 435 457 0.97

8 12 1.8e-05 0.0011 19.1 0.4 1 23 463 485 463 485 0.98

9 12 1.4e-06 8.8e-05 22.5 2.5 1 23 491 513 491 513 0.98

10 12 1.3e-05 0.00078 19.6 1.0 1 23 517 539 517 539 0.97

11 12 0.00035 0.022 15.0 0.4 1 21 547 567 547 571 0.92

12 12 3.6e-06 0.00022 21.3 0.3 3 23 592 613 590 613 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00083	0.051	13.8	1.9	1	20	214	233	214	235	0.94
2	12	2.6e-06	0.00016	21.7	0.4	3	23	286	307	284	307	0.93
3	12	0.25	15	6.1	0.0	1	23	313	335	313	335	0.94
4	12	5.1e-07	3.2e-05	23.9	2.4	1	21	342	362	342	363	0.95
5	12	5.8e-06	0.00036	20.6	1.0	2	23	375	396	374	396	0.96
6	12	0.00026	0.016	15.4	6.3	1	23	407	429	407	429	0.99
7	12	7.6e-05	0.0047	17.1	0.9	1	23	435	457	435	457	0.97
8	12	1.8e-05	0.0011	19.1	0.4	1	23	463	485	463	485	0.98
9	12	1.4e-06	8.8e-05	22.5	2.5	1	23	491	513	491	513	0.98
10	12	1.3e-05	0.00078	19.6	1.0	1	23	517	539	517	539	0.97
11	12	0.00035	0.022	15.0	0.4	1	21	547	567	547	571	0.92
12	12	3.6e-06	0.00022	21.3	0.3	3	23	592	613	590	613	0.97

Sequence Information

Coding Sequence: ATGAGCGCCTCCAAGGAGGGCAAGGAGAAGAAGATCAAGATACTGGGCGTGGAGAACATTTCGCCGCCCAAGGACAAGCGTCCTGCCACCAGAATGAAGCTCTTGAACGAGATAGGAGCAGCCGGAGATCCTGAAACCACCACCAGTAGCTCCTCATCAAAAACTCCCCCGAGTAAGCAGGAAAAACGAGGCACTGCATCCCGCATCAAAATACTCAATGAAGAAATCCTGGCCACGCCAAAGGCGGAGAAAAGGGGCGCCACCAAGGCGACCGCCTCCACAGTGAAGATTCTCAACGAGAAGCGGCTGCCCAGCGCCACCGTAACCGCCGTGGAAACGGCCAAGATCAAGACATCGCCCAGCAAGCGCAAGAAGATGGAGCACTATGTGCTGCAGGCGGTGAAGACCGAGAACAGCAAGGCGGACACCACGGTGACGGTGGCCACCGCCGAGGACGAGGAGACGATTGCCTACATTCTGGCCGACGATGAGGAGGTGGTGCCGGGTAGGATTCAGGACACCAATGGCCAGGAGATCGTTGTCACCGAGGAGGACGAGGACGACAAGGAAGACGGCGAGGAGGATGCGGAGGGCGAGGGCAACTCCAGCCACGGGGCAAAGATCAAGGAGATCGTGGAGCACGTGTGCGGCAAGTGCTACAAGACCTTCCGGCGCGTCCAGAGCCTCAAGAAGCATCTGGAGTTCTGTCGCTACGACAGCGGCTATCATCTGCGCAAGGCCGACATGCTCAAGAACCTGGAGAAGATCGAGAAGGATGCCGTGGTGATGGAGAAGAAGGACATCTGCTTCTGCTGCAGCGAAAGTTACGATACCTTTCATCTGGGCCACATCAACTGCCCCGACTGCCCCAAGTCGTTCAAGACGCAGACCAGCTACGAGCGCCACATCTTCATCACCCACTCCGAGTTCAGCGACTTTCCGTGCTCCATCTGCAATGCCAATCTGCGCAGCGAGGCCTTGCTGTCGCTCCACGAGGAGCAGCACAAGTCGCGTGGCAAGCCCTATGCCTGCAAGATCTGCGGCAAGGACTTCACGCGCTCCTACCACTTGAAGCGCCACCAGAAGTACTCGTCGTGTTCGTCGAACGAAACGGATACCATGAGCTGCAAGGTGTGCGATCGCGTCTTTTATCGCCTGGACAACCTGCGATCGCATCTCAAGCAGCACTTGGGCACGCAGGTGGTGAAGAAGCCCGAGTACATGTGCCACACGTGCAAGAACTGTTTCTACAGCCTGTCCACACTCAACATACACATACGCACACATACCGGCGAGAAACCCTTCGATTGCGATCTGTGCGACAAGAAGTTCTCCGCTTTGGTGGCCCTCAAAAAGCATCGACGCTATCACACTGGCGAGAAACCCTACAGTTGCACTGTGTGCAACCAAGCCTTTGCCGTCAAGGAAGTGCTCAATCGTCACATGAAGCGCCACACTGGCGAGCGACCACACAAGTGTGAGGAGTGCGGCAAGAGCTTCATCCAGGCCACCCAGCTGCGTACCCATTCCAAGACCCATATTCGCCCCTTTGCCTGCGATCAGTGCGAGGAGAAGTTCAAAACTGAGAAGCAACTTGAGCGCCATGTGAAGACTCACTCGCGCACAAAACGTCCCGTCTTCTCCTGCACCGAATGCAAGGCCACCTTCCGCACCACGGCGCTGCTCAAGGAGCACATGGACGAGGGCAAACACATCCCAAAAGAAAAAAGGACCACCAAGCGTTCGGCCATCAAAATTATGGAGCGAACGGATTGCGCCATTTGCGATAAGAACTTCGACAGCAGCGTAACGCTGCGCCGTCACATTCGCACCGTGCACGAGTGCGATCCCGATGATATCTTTGGCGTTGAACCGCAGCCTTCGAAGCGCGCAAAGAAGACGCCGCTCACTGAAATCGAAGATGATGAGGAGGTTGTCCCAGTGGCTCTCAACACTTCGGCGGGCTCCCTGATTTCCAGCCAAACGGATGGGAATGGCGTTGTGGTGCGCGAATTCCTGGTGGACGAGGGCGATGGCGCTGCCCAGACCATTACACTGGAAAACGAAACGTACACGATTCTCCCGTTGGACGGCGCCATCGAGGGAGAGCAGCTGACGGATGAAAGCGGTGTAAAGCCAGAGGGCAAAAAGGATGAGACACAGATCTCACCGGTGGTCAAGAAGGAGCAGCGCAAATCCCTGGCCGCCAGCTTGGCTGCTGCCATCGCGGATAATCTGGACGAAGCATCGAGCGAGGATGAGGTTAGCGGCGAAATCCTGACCGAAGAGGATCTAAAGCTTAAGGAGAACGTGGGCAAACTCATTGACATGCTGGTGGATCCGCCCATCCTGAAGAAATACGGGTGGCCCAATGCCCCCGAGGAGATGGTGCTCTGCAAGGTGATCGAGAACTGCGGCCACGACTTGCAAAAAGGTGCCGAGAACTACGCCGAACTGGACTACGGCAGTCGCATGCGGGAGTATTGCAAACTGCTCTTCACCGTTGTGATTCACAACGATTCCATCAAGTCGCTGCTCAACAATTTCCCCATCGACGATGTCATCGAGTATGTTCTGGGCGATGAGGAGCAGGAAGATGGCTTGGGAAAGGACAAGGAGGTCGAGGATAAGTCAGCTGCAGAGGATGATGAAGCGGAGACAATCACAGGCGATGCTGAAAAGGAGGAGATCCCAGAGAAACCTCAAATAAGTGCGACCTTAGAGGAAACTAAAGAGTCGGTAACAGAAGAGAAGAAAAAAGCTGCCCCATCGGAAACCGAAAAAGAAAAGGTTTGA
Protein Sequence: MSASKEGKEKKIKILGVENISPPKDKRPATRMKLLNEIGAAGDPETTTSSSSSKTPPSKQEKRGTASRIKILNEEILATPKAEKRGATKATASTVKILNEKRLPSATVTAVETAKIKTSPSKRKKMEHYVLQAVKTENSKADTTVTVATAEDEETIAYILADDEEVVPGRIQDTNGQEIVVTEEDEDDKEDGEEDAEGEGNSSHGAKIKEIVEHVCGKCYKTFRRVQSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLSLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHIRPFACDQCEEKFKTEKQLERHVKTHSRTKRPVFSCTECKATFRTTALLKEHMDEGKHIPKEKRTTKRSAIKIMERTDCAICDKNFDSSVTLRRHIRTVHECDPDDIFGVEPQPSKRAKKTPLTEIEDDEEVVPVALNTSAGSLISSQTDGNGVVVREFLVDEGDGAAQTITLENETYTILPLDGAIEGEQLTDESGVKPEGKKDETQISPVVKKEQRKSLAASLAAAIADNLDEASSEDEVSGEILTEEDLKLKENVGKLIDMLVDPPILKKYGWPNAPEEMVLCKVIENCGHDLQKGAENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEEQEDGLGKDKEVEDKSAAEDDEAETITGDAEKEEIPEKPQISATLEETKESVTEEKKKAAPSETEKEKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486704;
90% Identity: iTF_00602746; iTF_00486704; iTF_00604982; iTF_00581675; iTF_00548205; iTF_00578684; iTF_00536912;
80% Identity: -