Basic Information

Insect: Drosophila pseudotakahashii
Gene Symbol: su(Hw)
Assembly: GCA_035046095.1
Location: JAWNOE010000139.1:58963-62079[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00088 0.074 13.8 1.9 1 20 216 235 216 237 0.94

2 12 2.8e-06 0.00023 21.7 0.4 3 23 288 309 286 309 0.93

3 12 0.26 22 6.1 0.0 1 23 315 337 315 337 0.94

4 12 5.4e-07 4.6e-05 23.9 2.4 1 21 344 364 344 365 0.95

5 12 6.1e-06 0.00052 20.6 1.0 2 23 377 398 376 398 0.96

6 12 0.00028 0.024 15.4 6.3 1 23 409 431 409 431 0.99

7 12 8.1e-05 0.0068 17.1 0.9 1 23 437 459 437 459 0.97

8 12 1.9e-05 0.0016 19.1 0.4 1 23 465 487 465 487 0.98

9 12 1.5e-06 0.00013 22.5 2.5 1 23 493 515 493 515 0.98

10 12 4.1e-06 0.00034 21.2 1.0 1 23 519 541 519 541 0.97

11 12 0.00037 0.031 15.0 0.4 1 21 549 569 549 573 0.92

12 12 2.1e-06 0.00018 22.1 0.4 3 23 594 615 592 615 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00088	0.074	13.8	1.9	1	20	216	235	216	237	0.94
2	12	2.8e-06	0.00023	21.7	0.4	3	23	288	309	286	309	0.93
3	12	0.26	22	6.1	0.0	1	23	315	337	315	337	0.94
4	12	5.4e-07	4.6e-05	23.9	2.4	1	21	344	364	344	365	0.95
5	12	6.1e-06	0.00052	20.6	1.0	2	23	377	398	376	398	0.96
6	12	0.00028	0.024	15.4	6.3	1	23	409	431	409	431	0.99
7	12	8.1e-05	0.0068	17.1	0.9	1	23	437	459	437	459	0.97
8	12	1.9e-05	0.0016	19.1	0.4	1	23	465	487	465	487	0.98
9	12	1.5e-06	0.00013	22.5	2.5	1	23	493	515	493	515	0.98
10	12	4.1e-06	0.00034	21.2	1.0	1	23	519	541	519	541	0.97
11	12	0.00037	0.031	15.0	0.4	1	21	549	569	549	573	0.92
12	12	2.1e-06	0.00018	22.1	0.4	3	23	594	615	592	615	0.97

Sequence Information

Coding Sequence: ATGAGCGCCTCCAAGGAGGGCAAGGAAAAGAAGATCAAGATACTGGGCGTGGAAAACATTTCGCCGCCCAAGGATAAGCGTCCTGCCACCAGGATGAAGCTCTTGAATGACGTGGGAGCAGGCGGAGATGCTGAAACTACCTCCTCATCAAAAACTCCCCCGAATAAGCAGGAGAAACGCGGCAGCGTCACTGGATCCCGCATCAAAATACTCAATGAGGAAATACTGGCCACGCCAAAGGCGGAAAAAAGAGGCGCCACCAAGACCTCAAGTCCTGCCGCCTCCACTGTGAAGATTTTGAACGAGAAGAGGCTACCCAGCGCCACCGTAACAGCCGTGGAAACGGCCAAGATCAAGACATCACCCAGTAAGCGCAAGAAGATGGAGCACTATGTGCTGCAGGCTGTAAAAACGGAAAACAGCAAGGCGGACACCACGGTTACGGTGGCAACCGAAGAAGACGAGGAGACGATTGCCTATATTCTGGCCGATGACGAGGAAGTGGTGCCGGGAAGGATCCAGGACACCAATGGCCAGGAGATCGTTGTCAccgaggaggacgaggacgaaaAGGAAGACGGCGACGAGGACGGCGATGGCGAAGGCAACTCCAGCCACGGGACAAAGATCAAGGAGATCGTCGAGCACGTGTGCGGCAAGTGCTACAAGACCTTCCGCCGCGTTCAGAGTCTCAAGAAACATCTGGAGTTCTGTCGCTACGACAGCGGCTATCATCTGCGCAAGGCCGACATGCTCAAGAACCTGGAGAAGATCGAGAAGGATGCCGTGGTGATGGAGAAAAAGGacatttgcttttgctgcagCGAAAGTTACGACACCTTCCATCTGGGCCACATCAACTGTCCCGACTGCCCCAAGTCGTTTAAGACGCAGACCAGCTACGAGCGTCACATCTTCATCACCCACTCCGAGTTCAGCGACTTTCCGTGCTCCATCTGCAACGCCAATCTGCGCAGTGAGGCCTTGTTGTCGCTCCACGAGGAGCAGCACAAGTCGCGGGGCAAGCCATATGCCTGCAAGATCTGCGGCAAGGACTTCACGCGCTCCTACCACTTGAAGCGCCACCAGAAGTACTCATCGTGCTCGTCGAACGAAACCGATACCATGAGCTGCAAGGTGTGCGATCGCGTCTTCTATCGCCTGGACAACCTGCGATCGCATCTGAAGCAGCATTTGGGGACACAGGTGGTGAAGAAGCCGGAGTACATGTGCCACACGTGCAAGAATTGTTTCTACAGCCTGTCCACACTCAACATACACATACGCACACATACCGGGGAGAAACCGTTTGACTGCGATCTTTGCGACAAGAAGTTCTCCGCTTTGGTGGCCCTAAAAAAGCATCGACGCTATCACACTGGCGAGAAACCCTACAGTTGCACTGTGTGCAACCAAGCCTTTGCTGTCAAGGAAGTGCTCAATCGTCACATGAAGCGTCACACTGGGGAGCGACCACACAAGTGTGAGGAGTGTGGCAAGAGCTTCATCCAGGCCACCCAGCTGCGTACCCATTCCAAGACCCATATTCGCCCCTTTGCCTGCGATCAGTGCGAGGAGAAGTTCAAAACTGAGAAGCAACTTGAGCGCCATATTAAGACTCACTCGCGCACAAAACGTCCCGTCTTCTCCTGCACCGAATGCAAGGCTACCTTCCGCACCACAGCGCTGCTCAAGGAGCACATGGACGAAGGCAAACACATCCCAAAAGAAAAACGGACCACCAAGCGTTCTGCCATCAAAATTATGGAGCGAACAGATTGCGCCATTTGCGATAAGAACTTCGACAGCAGCGAAACACTGCGTCGGCACATTCGTACCGTGCACGAGTGCGATCCCGATGATATCTTCGGCGTTGAACCGCAGCCGTCGAAGCGTGCAAAGAAGGCGCCGCTCACTGAAATCGAAGATGATGAAGAGGTTGTACCGGTGGCGCTAAACACTTCGGCAGGCTCCTTGATTTCCAGCCAAACAGATGGAAATGGTGTTGTGGTGCGAGAATTCCTGGTGGACGAGGGCGATGGCGCTGCCCAGACCATTACACTGGAAAACGAAACTTACACGATTCTGCCTTTGGACGGGGCCATCGAGGGAGAGCAGCTGACGGATGAAAGTGCTGTCAAGCCTGAGGGCAAAAAGGATGAGGCCCAGGTCTCGCCGGTGGTCAAGAAAGAGCAGCGCAAATCCCTGGCGGCCAGCTTGGCTGCTGCCATCGCGGATAATCTAGACGAAGCATCGAGCGAGGATGAGGTTAGCGGCGAAATCCTGACTGAAGAGGATCTAAAGCTTAAGGAGAACGTGGGCAAACTCATTGACATGCTGGTGGATCCGCCCATCTTAAAGAAATACGGCTGGCCCAATGCCCCCGAGGAAATGGTGCTCTGCAAAGTGATTGAGAACTGCGGTCACGACTTGCAAAAAGGTGCCGAGAACTACGCAGAACTGGACTACGGCAGTCGCATGCGAGAGTATTGCAAACTGCTCTTCACCGTTGTTATTCACAACGATTCCATCAAGTCACTGCTCAACAATTTCCCCATCGACGATGTCATCGAGTATGTTCTGGGGGATGAGGATCAGGAAGATGGCTTGGGAAAGGACAAAGAAATCGAGGATAAGTCAACTGCAGAGGATGATGAAGCGGAGACGATCACAGGCGATGCTGAAAAGGAGGAGATCGCTGCGGAAACTAAGAAAAGTACGGTCGCGGCGGAAACTAAAGAGtcaaaaacagaagaaaagaaaaaaggtgCCCCATCGGAAGCTGAAAAAGGAAAGGTTTGA
Protein Sequence: MSASKEGKEKKIKILGVENISPPKDKRPATRMKLLNDVGAGGDAETTSSSKTPPNKQEKRGSVTGSRIKILNEEILATPKAEKRGATKTSSPAASTVKILNEKRLPSATVTAVETAKIKTSPSKRKKMEHYVLQAVKTENSKADTTVTVATEEDEETIAYILADDEEVVPGRIQDTNGQEIVVTEEDEDEKEDGDEDGDGEGNSSHGTKIKEIVEHVCGKCYKTFRRVQSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLSLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHIRPFACDQCEEKFKTEKQLERHIKTHSRTKRPVFSCTECKATFRTTALLKEHMDEGKHIPKEKRTTKRSAIKIMERTDCAICDKNFDSSETLRRHIRTVHECDPDDIFGVEPQPSKRAKKAPLTEIEDDEEVVPVALNTSAGSLISSQTDGNGVVVREFLVDEGDGAAQTITLENETYTILPLDGAIEGEQLTDESAVKPEGKKDEAQVSPVVKKEQRKSLAASLAAAIADNLDEASSEDEVSGEILTEEDLKLKENVGKLIDMLVDPPILKKYGWPNAPEEMVLCKVIENCGHDLQKGAENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEDGLGKDKEIEDKSTAEDDEAETITGDAEKEEIAAETKKSTVAAETKESKTEEKKKGAPSEAEKGKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486704;
90% Identity: iTF_00605714;
80% Identity: -