Basic Information

Gene Symbol
Aef1
Assembly
GCA_018150745.1
Location
JAECWP010000095.1:6078035-6079207[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0064 58 3.9 0.1 22 48 95 121 88 125 0.84
2 4 8.9e-06 0.081 13.1 0.0 21 52 122 153 120 155 0.89
3 4 0.011 1e+02 3.1 0.1 21 48 150 177 148 181 0.85
4 4 3.3e-05 0.3 11.2 0.1 21 47 178 204 176 211 0.88

Sequence Information

Coding Sequence
ATGATGCATATCAAAACTGGTATATCACCAGGAGCCCATAGTGCCGCCCAAGCGGCAGCCATGGCAGCTGCCCAGGCGGCCGCCGCCCAGGCTGCTGCAGCTGAACAGCAACCGCCTCCCTCATCACATTTAGTGCATCTGGCGACGCATAGTCCGACTATTCCTGGTGAACATTATCTGGCCGCCAATGGGCATGGCGAACATGCGGCTGAGGCCGGAAGTAATGGTTCCTCATCGGCTGCTAATGGTGGAGGCGGCGGTGGTGGTAGTGGACGAGAACCGGATAAACCCTTCCATTGCACTGTGTGCGATCGACGATTTCGCCAGCTGAGCACACTGACCAATCACGTAAAGATTCACACTGGCGAAAAACCATACAAATGCAGCGTTTGTGATAAGACCTTCCGTCAATCGTCAACGCTAACGAATCACCTGAAGATCCATACGGGCGAAAAGCCCTACAATTGCAACTACTGTCCCAAGCATTTCCGTCAGTTGAGCACATTGGCGAATCACGTCAAGATCCATACGGGTGAAAAGCCGTTCGAGTGCGTCATATGCAAGAAACAATTCCGGCAATCGAGTACACTGAATAATCACATAAAGATTCATGTCATGGACAAGGTCTACGTTCCTGTCAAGATCAAAACGGAGGAGGAGGAGGGGTGA
Protein Sequence
MMHIKTGISPGAHSAAQAAAMAAAQAAAAQAAAAEQQPPPSSHLVHLATHSPTIPGEHYLAANGHGEHAAEAGSNGSSSAANGGGGGGGSGREPDKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCSVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEEEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00604341;
90% Identity
iTF_00604341;
80% Identity
iTF_00604341;