Basic Information

Insect: Drosophila sucinea
Gene Symbol: ush
Assembly: GCA_018150745.1
Location: JAECWP010000045.1:138308-142489[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.045 3.3 8.4 0.0 1 20 211 230 211 232 0.89

2 9 0.00026 0.019 15.4 0.8 1 23 284 306 284 306 0.98

3 9 0.047 3.5 8.3 1.0 2 21 347 366 347 367 0.92

4 9 0.045 3.4 8.3 2.9 2 21 744 763 743 764 0.93

5 9 0.0084 0.62 10.6 0.0 3 21 822 840 820 841 0.91

6 9 0.0087 0.64 10.6 0.0 2 23 904 925 903 925 0.98

7 9 0.0035 0.26 11.8 1.3 1 23 931 953 931 953 0.99

8 9 0.00063 0.046 14.2 0.8 1 23 962 985 962 985 0.96

9 9 0.28 21 5.8 0.7 2 20 1104 1122 1103 1124 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.045	3.3	8.4	0.0	1	20	211	230	211	232	0.89
2	9	0.00026	0.019	15.4	0.8	1	23	284	306	284	306	0.98
3	9	0.047	3.5	8.3	1.0	2	21	347	366	347	367	0.92
4	9	0.045	3.4	8.3	2.9	2	21	744	763	743	764	0.93
5	9	0.0084	0.62	10.6	0.0	3	21	822	840	820	841	0.91
6	9	0.0087	0.64	10.6	0.0	2	23	904	925	903	925	0.98
7	9	0.0035	0.26	11.8	1.3	1	23	931	953	931	953	0.99
8	9	0.00063	0.046	14.2	0.8	1	23	962	985	962	985	0.96
9	9	0.28	21	5.8	0.7	2	20	1104	1122	1103	1124	0.91

Sequence Information

Coding Sequence: ATGGCCAATGAGGTGACCATTAAAAAGACTCCTCAGACAAACTTTCTTGTTAAATCCAAAGATTTAGCCGATCATGAGTTGGGCGAGGAGCAGCAGTTTGATGACCAAACCAACAACAATAATTCAAGCGATCAGGCAACAGAAGCCGAAGAGGAGACAAATTCCTTAGAAGAGTCTATAGATGAACTGGAGGACATCAATCGAATACAGGGAAAACAGCAACAAGACGCAAAAGAGGAAGGAGAAGATGAATCGATGGCAACGACGCCGCCGCGCAGTCCGAGAGCCGAGATTGACAACGATGCTGAGGCAACGGGAATCAATGTGTCGATAGTGCCCAAATTGGAGCAGCCGGCCACACCACCAACACCTCCATCGCCCTGCCCATCACCAGTAAGTGATTCGCCGGTTCTTCCATCGCCCTCGCCACCGCCGCCCCCGCCGCCGGCACCCATAGCGCTACCCAAATTGCGTCTAAATGCACTGCTAGCCTCCGATCCTGCACTCAAACCCGATGCCAAGGAGCTCAATCTGCTAGGATCTCCAGCAATGAGCAAATCATCACTGCCACCGCCACCACCACCCACTGAGCAGGCGGATCTTGTGGAGCCCCTGCTGAAGCCAGCGAGATTCATGTGTTTGCCATGTAGCATAGCCTTCAGTTCACCCTCGACTCTGGAGGCGCATCAGGCCTACTATTGCTCGCACCGGCCCAAGGAGACGCCCGAACAGGATGAGGCGGGAGGGGAGAAGGGCGCGGATGGATCAATCTCAAATGCAGCTAGTGGGACTAGCAGTAGCGGCTCCTCCAACGAACCGCCAGCCAAAATGGCCCGCCTGGGCAAGCAATATGCCTGCACGCAGTGCTCCTACAGTGCGGATAAGAAGGTCTCGCTCAATCGGCACATGCGAATGCATCAATCCTCGCCAGCAACAACAGCTCCATCGGTGGCACCACCCATCACAGCCAACGGAGTGGGTCTGGGGCTTAATCCCCTGCAGGAGGAGACCTCTAGTCAACATCAGCAAATCGATCGCTACTGCAGCGACTGTGATATCCGTTTCAACAATATCAAAACGTATCGAGCCCACAAGCAACATTATTGCAGTTCCCGGCGATCGGATGGCCAATTGACACCCAAACCGGAAGGTCAAAGTGCAGCCAGTGGTGCGAGTGCTGGAGCACTGGTAGGACAAACTGCTGCTGCACCTGGTGGAGCCAGTGGGGCTCTCAGTCCGCAGACTAATCGCAACCATGCCAATAAGACTCCCACTCCCGCCATGGTGGCAGCTGCGGCCGCTGCTGCTGCGGTCGCTGCCGCCTCTTTGCCGCCGGCACCTCAGCCCTTTCTGGCCCTGCCCACCAATCCAATCATCATAGTGCCCTGCTCATTGATTAGGGCAGCCAGTCTCATACCCGGTCCACTCACCACTACCACATCGGGAATTGTGAATCCCGAATCCACCTGCTTTACGCTCGACAATGGAGCACTCAAACCCCTAGCGACGGCTCTTAGCATGGCCAATCCCTTGCTGGATGCGGGTAAAGAAACGCCTTCATCCTCCACGACAACGGAGCAGTCGACAGCCGCAGCCACAGCTAAGCCAAGGAGCAGTCCCTCCGAGGGAATCAAACGCAAAGAAGCCACTGGAAGTCGTGAAACGGTTCCATTGGATCTCTCACTGTCGCGTCGTTCACCCATCTCTGCTTTGCTGCAGCGACCGGATCTTTTGATGGCAGGTCTAGGATTCGGCTTGGGTCTGGGCAAAGAGAATCTCCTAATGAATGAGAATCACCGGGTGGTGACCCCCGAACAGATTGTCTGTGCCCCATCATTGCCCAGCAGCCCATCGATGAGTCCCTCGCCAAAGCGACGCGCTGTGAGTCCAGCTCCAGGACGTAGCTCTTCGGGCGGAGGAAGTACCTCATCCATGTCGCCGCCCCAACAACTACAACAGCAGCAGCAGCAACACCAGCAGCAGCATTTATTGGACAATTTGCCACCTCTGCGTTCCATGTTGCCGGCGGAATACGCATTAACCGAATCCCTGCTGGCCAAAACTAATCCGGAACTTGCTTTGAAATTGGCTGCCGAATTGGCTGGCAAATTGGCAGCTGGATTCACAAGCTCAGTGTCCGCAGCGCCGACGGTGGCAGCACCTCCACCGACAGCGCCTGTCACGAGTTCCACCAATCAGCCGCAGATCTACGTGAAACAGGGTGTCTCCAAGTGCAAGGAGTGCAACATCGTCTTCTGTAAATATGAGAACTATTTGGCCCACAAGCAGCATTATTGTTCGGCACGCAACCAGGAGCCAAGTGGAGCAGGTGGAGGAAGTAATGACGGTGATAACTCCAATTCGAAATCTTCAACGCCACCAGCGGGAGCAGGCGGAATCGCTGGAGCCGGTGGAGTAGCCTCATCTGAGTCTTCACCTGCTGTGGCCTATCAGCAGTTGATTTGTGCTGCCTGCGGCATCAAGTACACATCCCTGGATAATCTAAGAGCTCATCAGAACTATTATTGCCCCAAGGGAGCCAACGCGGCGTCAGCTGCAGCTGCCGCCACAGTGCCACCATCCTCGGATGATCGACTGATAATGGTCAAGGAAAAGTGTATGAAATGCAAGGGTCTACATGATGCCAATCAATCCTGCCCAGCAAATGCAATAACGGCTGGAACTCCAACTAGCTCCACTAGTGTCAATAAATGTCCCGTCTGTGGTGTGGTCAGTCCCAGTGCGGCTCTCGCCCGCAAGCATATGGAAATGCATGGAACTGTAAAGGCATTCCGCTGCAGCATTTGCCAATACAAGGGCAACACCCTGCGTGGCATGCGCACCCACATCCGCACTCATTTCGATAAGAAGACCAGCGATATTTTCAATTGCGAATACTGCAACTATGCCTCCACCTATAAGGGAAATGTGCTTCGTCACATGAAGCTTTTGCATCCTCATGTGGCTACCATAAACTCACCATCCATATCGCCTGAATCGCGAGATCCGCACCAACAGGAAATGCTGCCCCTCCCCGATGTGGTCAACGGAGAAGCGGGAAGTTTCCATATAAAATCGGAGCCAATGGATCATATTGTGGCACCTGCTACACCAACTGCTCTACCGCCGCCACCACCAGCCACCTTAAGCCTGATGCATGAGAACAATAACTCACCCATTGCCACGCCGCACATTAAATCTGAACCTGGTCTCGATATTGATGTTTCGCTGCCCAGTTCCCTGGCCTTGGCTCCACCACCTGTGTCGTCGCCTGTTCTGGCGGCCGCTGCAGCGGATGCCATGAAGAAATACTGTTCCACCTGCGATATATCCTTCAATTATGTGAAAACTTTTTTGGCCCATAAGCAATTCTATTGCAAAAGTAAACTACAGCGACCCGAGGCCAGCGATAGCCCCAGTCCCAATCAAATGAGAATGGGTGGCGGCGGCGGCGGCGTTGGCGTTGGTGGTGTCCAGCCATTGCAATCCCCTAACGAATTGATAATGTTGCAAAAGAACAAGGAGAATCTACAGGAGGCGGCCATTTGA
Protein Sequence: MANEVTIKKTPQTNFLVKSKDLADHELGEEQQFDDQTNNNNSSDQATEAEEETNSLEESIDELEDINRIQGKQQQDAKEEGEDESMATTPPRSPRAEIDNDAEATGINVSIVPKLEQPATPPTPPSPCPSPVSDSPVLPSPSPPPPPPPAPIALPKLRLNALLASDPALKPDAKELNLLGSPAMSKSSLPPPPPPTEQADLVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRPKETPEQDEAGGEKGADGSISNAASGTSSSGSSNEPPAKMARLGKQYACTQCSYSADKKVSLNRHMRMHQSSPATTAPSVAPPITANGVGLGLNPLQEETSSQHQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEGQSAASGASAGALVGQTAAAPGGASGALSPQTNRNHANKTPTPAMVAAAAAAAAVAAASLPPAPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTTTSGIVNPESTCFTLDNGALKPLATALSMANPLLDAGKETPSSSTTTEQSTAAATAKPRSSPSEGIKRKEATGSRETVPLDLSLSRRSPISALLQRPDLLMAGLGFGLGLGKENLLMNENHRVVTPEQIVCAPSLPSSPSMSPSPKRRAVSPAPGRSSSGGGSTSSMSPPQQLQQQQQQHQQQHLLDNLPPLRSMLPAEYALTESLLAKTNPELALKLAAELAGKLAAGFTSSVSAAPTVAAPPPTAPVTSSTNQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEPSGAGGGSNDGDNSNSKSSTPPAGAGGIAGAGGVASSESSPAVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGANAASAAAAATVPPSSDDRLIMVKEKCMKCKGLHDANQSCPANAITAGTPTSSTSVNKCPVCGVVSPSAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDIFNCEYCNYASTYKGNVLRHMKLLHPHVATINSPSISPESRDPHQQEMLPLPDVVNGEAGSFHIKSEPMDHIVAPATPTALPPPPPATLSLMHENNNSPIATPHIKSEPGLDIDVSLPSSLALAPPPVSSPVLAAAAADAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLQRPEASDSPSPNQMRMGGGGGGVGVGGVQPLQSPNELIMLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00571428;
90% Identity: iTF_00555360;
80% Identity: -