Basic Information

Insect: Drosophila paulistorum
Gene Symbol: ush
Assembly: GCA_018152135.1
Location: JAECXG010000684.1:257916-277137[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0065 0.5 11.0 0.0 1 20 218 237 218 239 0.90

2 9 0.00028 0.022 15.3 0.8 1 23 291 313 291 313 0.98

3 9 0.05 3.9 8.2 1.0 2 21 353 372 353 373 0.92

4 9 0.048 3.7 8.3 2.9 2 21 744 763 743 764 0.93

5 9 0.009 0.69 10.6 0.0 3 21 823 841 821 842 0.91

6 9 0.33 25 5.7 0.0 2 23 902 923 901 923 0.97

7 9 0.0038 0.29 11.8 1.3 1 23 929 951 929 951 0.99

8 9 0.00067 0.052 14.1 0.8 1 23 1010 1033 1010 1033 0.96

9 9 0.3 23 5.8 0.7 2 20 1154 1172 1153 1174 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0065	0.5	11.0	0.0	1	20	218	237	218	239	0.90
2	9	0.00028	0.022	15.3	0.8	1	23	291	313	291	313	0.98
3	9	0.05	3.9	8.2	1.0	2	21	353	372	353	373	0.92
4	9	0.048	3.7	8.3	2.9	2	21	744	763	743	764	0.93
5	9	0.009	0.69	10.6	0.0	3	21	823	841	821	842	0.91
6	9	0.33	25	5.7	0.0	2	23	902	923	901	923	0.97
7	9	0.0038	0.29	11.8	1.3	1	23	929	951	929	951	0.99
8	9	0.00067	0.052	14.1	0.8	1	23	1010	1033	1010	1033	0.96
9	9	0.3	23	5.8	0.7	2	20	1154	1172	1153	1174	0.91

Sequence Information

Coding Sequence: ATGCTTAGCAGTTGCACTAAAGGTGATTGTTCCGATACCACAGAAGAGATGACTGTCGACAGTAGAGAATCCAAAGATTTAGCCGATCACGAGCTGGGCGAGGAGCATCAGTATGATGACCAAACCAACAATAATAATGGAAGCGATCAGGCAACAGAAGCCGAGGAGGAAACCAATTCCTTAGAAGAGTCTATAGATGAATTAGAGGAAATTAATCGAATACAGGGAAAACAGCAACAAGACCCAAAAGAGGAAGGAGAAGATGAATCAATGGCCACGACGCCACCGCGCAGTCCAAAAGCTAAGATTGAGGACGATGCTGCGGCGACGGCCATCAATGTGGACGATGGATCGATAGTCCCCAAATTGGAGGAACCGGCAACACCACCAACACCTCCTTCGCCATGCCTTTCACCTACAAGTCATTCGCCTGCTGCCCCATCGCCCCCTCCGCCACCGCTGGCGGCAGCAGTTTCGCTCCCAAAACTGCGGTTAAATGCATTGCTGGCCTCCGATCCTGCCCTAAAACCAGATGCTAAGGAGCTCAATTTGCTTGGATCACCAGCCATGAGCAAATCCTCTCTGCCCCCACCACCACCACCGTCAACTGAGCAGGCCGAGCTTGTCGAGCCCCTGCTGAAGCCTGCGAGATTCATGTGTTTGCCATGTGGCATAGCCTTCAGTTCACCCTCAACCCTGGAGGCTCATCAGGCCTACTATTGCTCGCACCGGCCCAAGGAAACGCCCGAGCAGGACGAGGCGGGAGGTGAGAAGGCAGCTGATGGATCAATCTCGAATGCAGCCAGCGGCGCAAGCAGTGGCGGCTCCTCCAACGAACCGCCAGCTAAAATGCCGCGCCTGGGCAAGCAATATGCCTGCACGCAGTGCTCCTACAGCGCGGATAAGAAGGTCTCACTCAACCGTCACATGCGGATGCATCAATCATCGCCAGCAACAGCTCCACCAACAGCACCGCCCATTACGGCCAACGGCGTGGGATTGGGGATTAATCAGCTGCAAGAGGACACTTCTAGTCAACATCAGCAAATCGATCGCTATTGCAGTGACTGTGATATCCGTTTCAACAATATCAAGACGTATCGAGCGCATAAGCAACATTATTGCAGTTCCCGGCGATCGGATGGCCAAGTGACACCCAAACCGGAAGGCCAAAGTGCTGCCAGCGGACCCAGTGGCAGTGTAACTGGAGGTGGGCAAGCTGTAGCGGCAAGTGGTGGAGCCAGTGGGGCGCTAAGTCCTCAGACTAATCGCAATCATGCCAATAAGACTCCCACTCCCGCAATGGTAGCTGCTGCGGCGGCTGCTGCTGCTGCAGCGGCTGCCGCTTCTCTGCCCCCGCCTCCTCAGCCGTTTTTGGCGTTGCCCACCAATCCAATCATTATAGTGCCCTGCTCATTGATCAGGGCAGCCAGTCTCATACCCGGACCACTCACCACTGCCACTTCGGGAATTGTAAATCCAGAATCCACCTGCTTTACTCTCGACAGTGGAGCACTTAAACCCCTTGCGACGGCCCTCAACATGGCCAATCCCCTGCTGGAGGCGGGCAAGGAAACGGCCTCATCCTCTTCAACAACGGAGCAGCCAACGGCTGCAGCTAAACCAAGGAGCAGTCCCTCAGAGGGAGTAAAACGCAAAGAAACCACTGGGAATCGTGAAACGGTTCCATTAGATCTCTCATTGTCCCGTCGTTCGCCCATCACTGCTTTGCTCCAGCGACCGGATCTTCTAATGGCTGGCCTAGGCTTTGGCTTGGGATTGGGCAAAGAGAATCTCCTAATGAATGAGAATCATCGTGTGGTGACCCCCGAACAGATTGTCTGTGCCCCATCATTGCCTAGCAGTCCCTCGATGAGTCCTTCTCCAAAGCGACGAGCCGTAAGTCCAGCACCACCACGAAGCTCTTCGGGCGGCGGAAGTACAGCATCCATGTCACCGCCCCAGCAGCAGCAACAGCAGCAGCATTTATTGGACAACTTGCCACCACTGCGTTCCATGTTGCCTGCGGAATACGCTTTAACCGAATCTCTGCTGGCCAAAACGAATCCGGAACTTGCTCTAAAATTGGCTGCCGAGTTAGCTGGGAAACTGGCGGCTGGGTTCACCGGATCAGTGGCCACAGCGCCGACGGTGGCAGCACCTCCACCTGCAGCACCTGTCACTGGTTCCAGCAATCAGCCGCAGATCTATGTGAAACAGGGCGTGTCCAAGTGCAAAGAGTGCAACATCGTTTTCTGTAAATATGAGAACTATTTGGCCCACAAGCAACATTACTGTTCGGCACGCAACCAGGAGACACCTGGAGGAGGAGGCCCGGGAAGTGTTGATGGCGATAACTCCAATTCGAAATCCTCATCACCTCCAGCGGGAGCAGCAGGCGTCTCAAATGCTAGTGGAGTAGCTTCAGCCGAATCTTCACCAGCTGTGGCCTATCAGCAATTGATTTGTGCAGCCTGCGGCATTAAGTACACATCCCTGGATAATCTAAGAGCTCATCAGAACTATTACTGTCCCAAGGGAGCCAATGCGGCTCCAGTTTCCACTGGGCCCACAGCGGATGACCGCCTTATTGTGGTCAAGGAAAAGTGTATGAAGTGCAAAAGTTCGCATGATGCCAACTCGCCGTGTCCTGCAAGTGCCGTAACGAGTGGAACTCCAACTAGTTCCACAACTAGTGTCAACAAATGTCCCGTTTGTGCCGTAGTCAGTCCCAGCGCTGCTCTCGCACGGAAGCATATGGAAATGCATGGAACCGTTAAGGCATTTCGATGCAGTATTTGCCAATACAAGGGCAACACCCTGCGGGGCATGCGCACCCATATCCGGACCCATTTCGACAAAAAGACCAGCGATGTCAACGAGGAGCACTACATGACCTGCATCTTCGAAGAGGAAGCAGCCGCCTTGACAGCCTCAGGAACAGCCGTCGGAGGTGGAGGTGGCGGTGGAGTAGATTTGCCATCGTCAGCTTTAGCACCGGATCAACTGGACCAGCAGCCACAGATTTTCAATTGCGAATATTGCAATTATGCCTCCACCTATAAGGGCAATGTGCTGCGTCACATGAAGCTTCTGCATCCCCATGTGGCTACCATAAACTCACCATCCATATCGCCCGAATCGCGTGATTCACACCAACAGGACATCCTGGGCAACTCCCTATCTGATGTGGTAAACGGAGAACTGGCAAGTTTTCATATAAAATCAGAGCCCATGGATCATACAGTGGCGCCTTCTGCCCTGCCTTCTGCTCTACCTCCACCACCACCGCCCACCTTAAGCTTGATCCATGAGAACAATAACTCGCCCATTGCCACACCGCACATTAAATCTGAACCTGGCCTCGATATTGATGTGTCGCCGCCCAGTTCGCTGGCCTTGGCTCCACCTGTGTCTTCACCTGTTTTAGCTGCTGCTGCAGCGGAGGCCATGAAAAAATACTGTTCCACCTGCGATATATCCTTTAACTATGTGAAAACCTTTTTGGCCCACAAGCAATTCTATTGCAAGAGCAAGCTGCAGCGGCCCGAGGCCAGCGATAGCCCCAGCCCCAATCAGATGAGTAGCGTCGGTGGAGCAGCAACAGGTGGTGGAGTGGTGGGTTTGCTAGGAATGAGTGGCGGCGGCGGTACGGGTGTCCAACCACTGCAATCTCCTAGCGAATTGATGATGCTGCAGAAGAACAAGGAGAATCTACAGGAGGCGGCCATTTGA
Protein Sequence: MLSSCTKGDCSDTTEEMTVDSRESKDLADHELGEEHQYDDQTNNNNGSDQATEAEEETNSLEESIDELEEINRIQGKQQQDPKEEGEDESMATTPPRSPKAKIEDDAAATAINVDDGSIVPKLEEPATPPTPPSPCLSPTSHSPAAPSPPPPPLAAAVSLPKLRLNALLASDPALKPDAKELNLLGSPAMSKSSLPPPPPPSTEQAELVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRPKETPEQDEAGGEKAADGSISNAASGASSGGSSNEPPAKMPRLGKQYACTQCSYSADKKVSLNRHMRMHQSSPATAPPTAPPITANGVGLGINQLQEDTSSQHQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQVTPKPEGQSAASGPSGSVTGGGQAVAASGGASGALSPQTNRNHANKTPTPAMVAAAAAAAAAAAAASLPPPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTATSGIVNPESTCFTLDSGALKPLATALNMANPLLEAGKETASSSSTTEQPTAAAKPRSSPSEGVKRKETTGNRETVPLDLSLSRRSPITALLQRPDLLMAGLGFGLGLGKENLLMNENHRVVTPEQIVCAPSLPSSPSMSPSPKRRAVSPAPPRSSSGGGSTASMSPPQQQQQQQHLLDNLPPLRSMLPAEYALTESLLAKTNPELALKLAAELAGKLAAGFTGSVATAPTVAAPPPAAPVTGSSNQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQETPGGGGPGSVDGDNSNSKSSSPPAGAAGVSNASGVASAESSPAVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGANAAPVSTGPTADDRLIVVKEKCMKCKSSHDANSPCPASAVTSGTPTSSTTSVNKCPVCAVVSPSAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEAAALTASGTAVGGGGGGGVDLPSSALAPDQLDQQPQIFNCEYCNYASTYKGNVLRHMKLLHPHVATINSPSISPESRDSHQQDILGNSLSDVVNGELASFHIKSEPMDHTVAPSALPSALPPPPPPTLSLIHENNNSPIATPHIKSEPGLDIDVSPPSSLALAPPVSSPVLAAAAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLQRPEASDSPSPNQMSSVGGAATGGGVVGLLGMSGGGGTGVQPLQSPSELMMLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612337; iTF_00618677; iTF_00503557; iTF_00604361; iTF_00555360; iTF_00523949;
90% Identity: iTF_00503557; iTF_00523949; iTF_00612337; iTF_00618677;
80% Identity: -