Basic Information

Insect: Drosophila sucinea
Gene Symbol: -
Assembly: GCA_018150745.1
Location: JAECWP010000127.1:9732360-9734244[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.5e-05 0.0019 18.6 2.8 1 23 104 126 104 126 0.97

2 11 1.1e-06 8.1e-05 22.9 2.5 1 23 132 155 132 155 0.97

3 11 3.9e-05 0.0029 18.0 0.3 1 23 161 183 161 183 0.97

4 11 1.5e-05 0.0011 19.3 0.4 1 23 189 211 189 212 0.95

5 11 1e-06 7.6e-05 23.0 0.5 1 23 219 241 219 241 0.97

6 11 0.0092 0.68 10.5 0.9 1 23 247 270 247 271 0.95

7 11 0.0021 0.16 12.5 0.2 1 23 276 298 276 298 0.97

8 11 2e-05 0.0015 18.9 2.7 1 23 304 326 304 326 0.98

9 11 1.8e-05 0.0013 19.0 4.7 1 23 332 354 332 354 0.99

10 11 0.0056 0.41 11.2 1.1 1 23 360 385 360 385 0.92

11 11 0.0013 0.098 13.2 0.6 1 19 391 409 391 412 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.5e-05	0.0019	18.6	2.8	1	23	104	126	104	126	0.97
2	11	1.1e-06	8.1e-05	22.9	2.5	1	23	132	155	132	155	0.97
3	11	3.9e-05	0.0029	18.0	0.3	1	23	161	183	161	183	0.97
4	11	1.5e-05	0.0011	19.3	0.4	1	23	189	211	189	212	0.95
5	11	1e-06	7.6e-05	23.0	0.5	1	23	219	241	219	241	0.97
6	11	0.0092	0.68	10.5	0.9	1	23	247	270	247	271	0.95
7	11	0.0021	0.16	12.5	0.2	1	23	276	298	276	298	0.97
8	11	2e-05	0.0015	18.9	2.7	1	23	304	326	304	326	0.98
9	11	1.8e-05	0.0013	19.0	4.7	1	23	332	354	332	354	0.99
10	11	0.0056	0.41	11.2	1.1	1	23	360	385	360	385	0.92
11	11	0.0013	0.098	13.2	0.6	1	19	391	409	391	412	0.94

Sequence Information

Coding Sequence: ATGGCACGCAGCCGTCGCAGTTTGTCCAAAGAGGATGCCGTCTCCCTGCTTACAGACAGTGGCATATCGCTATCATCGCCGCCGGCGGCGGGCAGAGACTCATCATCGCCCACAACAACATTATCGATCAAGCGCCGCAAAAGCAGTCTAAGGGACAATAACTATGCGGAGGCTGATGGTGAAGATGATGACACGGAACAGGATTCCCGGGATGCAGACTATATACAGCCCTTGCCCAAGAAATCGTCAAGGAAATCATCGATAGCATCATCATCAGCATCGCCAACCGAATCGGGGCGACGCAAGCATCACGTTTGTACACATTGCTCCAAGGAATTTGGCGGTAAAACTGATCTGCAGCGCCACATGCTCATCCATTCGGATGAGCGGCCACATAAGTGTGCCGAATGTGGTAAATGCTATCGCCAGGCAGTGAATCTTAAGAATCACATAACCACCGCTCATGAGCACAAGAAGCAATTTGCCTGTGGCCAGTGTCCCAAATCGTTTGCCCTCAAAGAGCGACTGCGTCTGCATATGCGTTTGCATTCGGGCGAGAAACCATATCCGTGTGCTCTATGTGATAAGCGTTTCGCCAGGGGTGGTCAGCTCCAGCAGCATATGGTGTCGCATCATAAGACGAGTATACAGCAATTCAATTGCACCGAATGCTCGGCCAGCTTCTCGACCAATGCCAATCTGCGTGTACATATGGAGAGGCATGAGCAGGGAATGGAGCACAGATGCAGCATCTGTGAGAATCCATTTATGAATGAATTGGCACTGCGTGCCCACATCAATCAGGAGCATCATAAGCTCACGAAATTCGATTGTGAGATTTGCCACAAGAGCATCGAACCGGATGAGGATCTCGCCACCCATATGCAAAAGCATGCGACCATTAAAACGCATGTGTGTGAGGTGTGCAATTCGTATTTTACTCAGAAATCGCAATACAATGTCCATATGCGTATGCATACAGGCGAGCGACCATATCAGTGTCGAATCTGTCATCAAACCTTTGCCCACTCGAGTGTACTGAAGCTGCATATACGAAAACACACCGGTGAGAAACCATTTCGTTGTCTCCTATGTACCGATGAAGTGGCCTTCTCGCAATTGGCCCATCTTAAGAATCACATGAAGAAAATCCATAAGCAACAGAAACCCTATATGTGCCATGGATGTCATGAGTTCTTTAAAATCAAGGTGGAACTGCAGGCACATGCCGAAAACTGCGCTAAATGCCAAAAGTCAGGCGATGAGGATGAGAATCAAAGTGAAAATGCTCAGGCATTGTCCACCATGCGTTTCAATATGGCTGTGGTGCTCAAGAAAATTAGCTCCGCCCAGAAACTACGCCAATTGGGCTATGAGAAACGTTTAATTGACAATGTTATAATTGCCTCACTCAAATTGGCCCAGCGTCCGGCTCATGATGATGCCCAATTAACGCCATTGGCTCGCCTACGGCTTAATGTGGAGGAGTTCCTCAAATGGATTGTGCCAGCGCCGACTATGCAGAAATTTAGCGAAGAGTTGCTTTCGGTTGAGACTATTCTCGATAAGATTGCCACCATGTATATGAAGCAAAAGTAG
Protein Sequence: MARSRRSLSKEDAVSLLTDSGISLSSPPAAGRDSSSPTTTLSIKRRKSSLRDNNYAEADGEDDDTEQDSRDADYIQPLPKKSSRKSSIASSSASPTESGRRKHHVCTHCSKEFGGKTDLQRHMLIHSDERPHKCAECGKCYRQAVNLKNHITTAHEHKKQFACGQCPKSFALKERLRLHMRLHSGEKPYPCALCDKRFARGGQLQQHMVSHHKTSIQQFNCTECSASFSTNANLRVHMERHEQGMEHRCSICENPFMNELALRAHINQEHHKLTKFDCEICHKSIEPDEDLATHMQKHATIKTHVCEVCNSYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCLLCTDEVAFSQLAHLKNHMKKIHKQQKPYMCHGCHEFFKIKVELQAHAENCAKCQKSGDEDENQSENAQALSTMRFNMAVVLKKISSAQKLRQLGYEKRLIDNVIIASLKLAQRPAHDDAQLTPLARLRLNVEEFLKWIVPAPTMQKFSEELLSVETILDKIATMYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612236;
90% Identity: iTF_00618578;
80% Identity: iTF_00555254;