Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: BCL11A
Assembly: GCA_035043285.1
Location: JAWNNB010002033.1:1318219-1334008[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.026 1.9 9.2 2.4 1 23 232 255 232 255 0.95

2 6 1.4e-06 0.0001 22.7 1.5 1 23 722 744 722 744 0.98

3 6 0.012 0.87 10.3 4.7 1 23 750 772 750 772 0.99

4 6 1.1e-06 8.1e-05 23.0 3.2 2 23 1053 1074 1052 1074 0.97

5 6 1.5e-05 0.0011 19.5 3.3 1 23 1080 1102 1080 1102 0.99

6 6 2.7e-05 0.002 18.6 0.4 1 22 1110 1131 1110 1131 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.026	1.9	9.2	2.4	1	23	232	255	232	255	0.95
2	6	1.4e-06	0.0001	22.7	1.5	1	23	722	744	722	744	0.98
3	6	0.012	0.87	10.3	4.7	1	23	750	772	750	772	0.99
4	6	1.1e-06	8.1e-05	23.0	3.2	2	23	1053	1074	1052	1074	0.97
5	6	1.5e-05	0.0011	19.5	3.3	1	23	1080	1102	1080	1102	0.99
6	6	2.7e-05	0.002	18.6	0.4	1	22	1110	1131	1110	1131	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAATGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGTCATTCCGACTCCACAGAGAACGATGCGGTTGCCGCACAGGACATCCTCACGTGCGGCGCCTGCCAGAAGGCATTCGCCCTCTCGGACATTGTCAAGTTCATCCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGCTCCACGCAGGGTCCCCAGATGGACCGTGACACGGAGGAGGGCCGCCCCCTGAGCCTCGTCAATCGCCGTCCCTCGATCTCGGCCATACCCATCACAGGCCGCAAcAGCACGGCCAGCGGCTCCCGTATACACACCCCGCCACCAAGTCCCGCTGATCTGCTGGCCGATGGCGCCAGCAGCACGCCCAAGCGTCTCGTTGACGAGAACGACAACACAACGCCCAAGGACAGCGAGGCGGCAGCCACCACCGTGTCATCCATGCGCGGCAGTCCGGCGGCCATTGAGCGTCAGACGGCCAGCGACATCAGCTGCGATCTGCTCGACGAGGAGCAGCACCCACACACCCCCAAGGTCAAGCAGGAGCCCTTTGCCGGCGACGAGGagatgcagcaggagcagtccGTGATTGCCGATTGCCAGCCCCTGGCCAAGCGGCCCAAAATGGAGCTGGTCGATGCCGAGGCCAACACAGTCCACACAGAGCCCAGCAATTACACATGCTCCACCTGCAAGACCCGCTACACATCCGCGTGGCGCCTCATCCAGCACGTCCAGCACTCGCACGGCGTGAAGATCTATGTGGAGGCCACTGGCGGCGCCACCCTCACCGTGGCCACGCCCGCAGCCCTCAATAACAGCGCCCTGGCCGtcgctgcagccgctgcagcagccgccgctgccgttgcgGCTGGCGTTAGTCCACAGCCCGCTGAGGCGGCGATGAAGCGCAGCAGcccagctggagctggagtcgCCTCCGTCTCCCTGTCCACCTCCGTCAGTTCCACATCCTCCGCGTCGCTGGCCAACACgagcggcggcagcaacagcagccacgcCAGCCACGCCAGCCATGGCAGTGTCAGTGCCGTCAGCATCAGCGCCTCGtccccccagcagcagcagcagcagcagttgcagttgcaccaacagcagcagcagcagcaacaacagcaacaggcagcgcaacagcaacaacagcgcgtgcatcagcagcagcgcgagaaCCTGGCATCGGCAATGGCCGCCGGAATGCGTCATCATCCGCTGCTGGCGCCGCCAGAGGCGATGCATGCCAATCCCTTCCAGCTGCTGCGCATGCCCCTGCCGCCGGCGTTGGCCCAGGGCAATGTAGTTCCTAGCGTGGCGCCACTGTTCGGGCACGGCCGCCCCTCGCCCGCCGACCACTACCGCATGGAGCAGCTGGTGAGCGAACAGTTCCGGCATCACGGCTTCAATctggcagccgctgccgccgccgcccaggCACAGTTCAATGCCAACGGGCAGGTGGGAGGACAGCAGTTGAATGTGTCCGCCAATGTTCCTACCGTCGCCAGTGGCGAGCCGCGTCCACCCTCGagctccagcagcggcagccagcgTGGCTCCGTGCCGCCCGCCGCCCTGCCACCACCGTCTCTCagctcccagcagcagcagcagcagcagcagcagcagcaacaacagcagcagcagcagcaggcaggaggcgCCTCCACGCCCGGTCtggtgggaggaggaggaggaggaggcagtggATCCCTGAAGCTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAGCATTGTTAACTCGAGCTCGCCGAGTCCTCGACAGAAGCAATCGCCGCATTTCGCGAGCCCCTCGCCCTCCCAGCTAccccagcaccaccaccaccagcggcCCCACTCGCTGACGCCGCCAGAGAAGAGCGGAGATGCGGGCTCCGAGAACGGCAGCCTGGGCAGCCTCGGCCTCGCCCTGGCCAGCACCCCGCGATCGGCCAGTACGCCGCCGTCGAAGGGCAGCgccggtgtcggtgtcggtgccGGAGGCCTCAGTTTGGGCCTCAATCTCGGCCAGGTGGgcggaggagtaggagtaggagtaggagtaggagcggaGCAGGCCAGCTGCTATGCGTGCAGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAACCTGATCATCCACCAGCGGACGCACACGGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTTGAGTGCTCCCACATCCAGAAGCTGATGAAGCACATGCGGGTGCACCGCAGTCCTGGGGATGACCAGGACGGACAGGATGGGCCCGACGATGGCAGCAATGCCGATTCGCTGGAGACGAACGAGGCGGACAACGACGAGGATCCCAATCCGGATGAGTCCGAGGAGGAGATGGGCGATGCCGATGGCGACAATGATCCCGACGGTGATGGCGATGTCGATCCCGATgccgatggcgatggcgagggcgacgacgaggacgaggacgagctgGACGACTGCGAGGACATGGACTACAAGGCCGAGGATCTGAGCGTGAGCAACCGCATCGACGgcaagagccagagccccaAGACGACCAGCTCCGGCGCCACCTCCCTGGTCGGGGAGCTGATGGACAAGTTCGGGCTCTCGAACATCGCCCAGTACAGCGAGGCCTACAAGCAGGCGCTGCAGGAGTCCGGCCGCAAGGAGGCCGCCTCCgtggccgccgctgccgccgccgctgcagcagccgcagccgctgtGGACAACAACAACCGGGGCGGAAGCTCGGGACCCGGCTCTGCCTCTGGAGCGGGTGGCGCCGACAAGATGAACGGCCTGCCCGTGGCCGCACTCCGGCTGCGGGACGAGTTCGCCAAGAACTGCAACATGTTCCAGCAGCCGCAGGATGGGCCCGGCCAGGTGCCGCTCTTCAATCCCTTCCCCAATCCCTTCGAGCTGAGCAAGCGCATGAAGATGGACGGCGACTGGTGGGGCATGTCCGCCCTGCACCGCAACGAGGCGCTCTTCGAGAACCTCAAGCTGAAGCCCCTGGGCCTCGGTGGCGCCAATGCGCTCATCCAGGGTCCGCTGCTCAAGAAGGAGAGCCGCCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACGGTCCACCGGCGCAGCCACACGGGCGAGAAGCCGTACAAGTGCGAGCTCTGCTCCTACGCCTGCGCCCAGAGCTCGAAGCTCACCCGCCACATGAAGACGCACGGACGCACCGGCAAGGATGTGTATCGCTGCCGCTTCTGCGACATGCCCTTCAGCGTCCCCTCCACCCTCGAGAAGCACATGCGCAAGTGTGTGGTGAACCAGGGCAAGGCGGCAGCCGCCGCCAATGCCGTAGCCGCTGCTCAGGCCGCCCAAGCTGCcgcccagcagctgcaggcagcCGCCCAGCATGCCCAGGccgcccaacagcagcagcagcagcagcaccagcagtcgcagcagcaacagcagtcgcagcagcagatgccCGTGCAGTCACAGCTGTCGCCCACCTGCCCCATGGGCGTGGTCGGGTATCCGCCACAGTTTGGAGTCTCCGTTGGGGGCCACAACCTCTCGCTGCCGGGCAGCGTGAGCGGGGACAACGACTCGAATGCGTCCTCCAGCCTCACAGTACATCCCATTTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCSTQGPQMDRDTEEGRPLSLVNRRPSISAIPITGRNSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSEAAATTVSSMRGSPAAIERQTASDISCDLLDEEQHPHTPKVKQEPFAGDEEMQQEQSVIADCQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEATGGATLTVATPAALNNSALAVAAAAAAAAAAVAAGVSPQPAEAAMKRSSPAGAGVASVSLSTSVSSTSSASLANTSGGSNSSHASHASHGSVSAVSISASSPQQQQQQQLQLHQQQQQQQQQQQAAQQQQQRVHQQQRENLASAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPSVAPLFGHGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVGGQQLNVSANVPTVASGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQAGGASTPGLVGGGGGGGSGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSIVNSSSPSPRQKQSPHFASPSPSQLPQHHHHQRPHSLTPPEKSGDAGSENGSLGSLGLALASTPRSASTPPSKGSAGVGVGAGGLSLGLNLGQVGGGVGVGVGVGAEQASCYACSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPGDDQDGQDGPDDGSNADSLETNEADNDEDPNPDESEEEMGDADGDNDPDGDGDVDPDADGDGEGDDEDEDELDDCEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAASVAAAAAAAAAAAAAVDNNNRGGSSGPGSASGAGGADKMNGLPVAALRLRDEFAKNCNMFQQPQDGPGQVPLFNPFPNPFELSKRMKMDGDWWGMSALHRNEALFENLKLKPLGLGGANALIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQQLQAAAQHAQAAQQQQQQQHQQSQQQQQSQQQMPVQSQLSPTCPMGVVGYPPQFGVSVGGHNLSLPGSVSGDNDSNASSSLTVHPISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564188;
90% Identity: iTF_00471880;
80% Identity: -