Basic Information

Insect: Drosophila affinis
Gene Symbol: BCL11A
Assembly: GCA_037356375.1
Location: CM074802.1:10682680-10697228[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.026 2.2 9.2 2.4 1 23 245 268 245 268 0.95

2 6 1.4e-06 0.00012 22.7 1.5 1 23 725 747 725 747 0.98

3 6 0.012 1 10.3 4.7 1 23 753 775 753 775 0.99

4 6 1.1e-06 9.4e-05 23.0 3.2 2 23 1055 1076 1054 1076 0.97

5 6 1.5e-05 0.0012 19.5 3.3 1 23 1082 1104 1082 1104 0.99

6 6 2.7e-05 0.0023 18.6 0.4 1 22 1112 1133 1112 1133 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.026	2.2	9.2	2.4	1	23	245	268	245	268	0.95
2	6	1.4e-06	0.00012	22.7	1.5	1	23	725	747	725	747	0.98
3	6	0.012	1	10.3	4.7	1	23	753	775	753	775	0.99
4	6	1.1e-06	9.4e-05	23.0	3.2	2	23	1055	1076	1054	1076	0.97
5	6	1.5e-05	0.0012	19.5	3.3	1	23	1082	1104	1082	1104	0.99
6	6	2.7e-05	0.0023	18.6	0.4	1	22	1112	1133	1112	1133	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAATGCTGTCGATCAGTGAGGATCACGGATTCCGTTCGCTGAGTCATTCCGACTCCACAGAGAACGATGCGGTTGCCGCACAGGACATCCTTACGTGCGGCGCCTGCCAGAAGGCGTTCGCCCTCTCGGACATTGTCAAGTTCATCCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGCTCCACGCAGGGTCCCCAGATGGACCGCGACGCGGAGGAGGGCCGCCCCCTGAGCCTCGTCAACCGCCGGCCCTCGATCTCGGCCATACCCATCACAGGCCGCAAcAGCACGGCCAGCGGCTCCCGCATACACACCCCGCCACCAAGTCCCGCGGATCTGCTGGCCGACGGCGCCAGCAGCACGCCCAAGCGTCTCGTTGACGAGAACGACAACACAACGCCCAAGGACAGCGAGACGGCAGCCACCACCCTGGACTCCAATGCCGTGGCATCCATGCGCGGCAGTCCGGCGGCCATTGAGCGCCAGGCGGCCGGCGACAGCAGCTGCGATCTGCTCGACGAGGAGCAGcatccacacacacccaaGGTCAAGCAGGAGCCCTATGCCGGCGACGAGGAGATGCCCCAGCTCGACCacgaacaggagcaggagcaggagcagtccGTGGCCGACTGCCAGCCCCTGGCCAAGCGGCCCAAAATGGAGCTGGTCGATGCCGAGGCCAATACAGTCCACACAGAACCCAGCAATTACACGTGCTCCACTTGCAAGACCCGCTACACATCCGCGTGGCGCCTCATCCAGCACGTCCAGCACTCGCACGGCGTCAAGATCTACGTGGAGGCCACTGGGGGTGCCACCCTCACCGTGGCCACGCCCGCCGCCCTCAACAACAGCGCCCTGgccgccgctgcagccgctgcagcagccgctgccgccgttGCGGTGGGCGCCAGTCCACAGCCCGCTGAGGCGACGATGAAGCGCAGCAGTCCCGCTGGAGCGGGAGTCGCCTCCGTCTCCCTGTCCACCTCCGTCAGTTCCACATCATCCGCGTCGCTGGCCAACACGAGcatcggcagtggcagcaacagcagtcacGCCAGCGGCAGCGCCGGCGTGAGCATCAGCGCCTCGTCcccccaacaacagcagcagcagcagcagttgcagttgcaccaacagcagcaacaacagcagcagcagcagcaacaggcggtgcaacagcagcagcagcgcgtgcagcagcagcagcgcgagAACCTCGCCTCGGCAATGGCCGCCGGAATGCGTCACCATCCGCTGCTGGCGCCTCCCGAGGCGATGCATGCCAATCCCTTCCAGCTGCTGCGCATGCCCCTGCCGCCGGCGTTGGCCCAGGGAAACGTAGTTCCTAGCGTGGCGCCACTGTTCGGCCACGGCCGCCCCTCGCCCGCCGACCACTACCGCATGGAGCAGCTGGTGAGCGAGCAGTTCCGGCACCACGGCTTCAATctggcagcagccgccgccgccgcccaggCGCAGTTCAACGCCAACGGGCAGGTGGGAGGACAGCAGTTGAATGTGTCCGCCAATGTTCCTACCGTCGCCAGTGGCGAGCCGCGTCCGCCCTCGAgctccagcagcggcagccagcgCGGCTCCGTGCCGCCCGCCGCCCTGCCACCGCCGTCGCTCagctcccagcagcagcagcaacagcagcagcaacaacagcagcagcagcaacagcagcagcagcagcaggcgggaGGCGCCTCCACGCCTGGCCTGGTGGGAGGAGGCAGCGGCTCCTTGAAGCTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAGCATTGTTAACTCGAGCTCGCCGAGTCCTCGACAGAAGCAATCGCCGCATTTCGCGAGCCCCTCGCCCTCCCAGATCccccagcaccaccaccaccagcggCCCCACTCGCTGACTCCCCCCGAGAAGAGCGGAGATGCGGGCTCCGAGAACGGCAGTCTGGGCGGCCTCGGCCTGGCCCTCGCCAGCACCCCGCGGTCGGCCAGCACGCCACCATCGAAGGGCAGCAGCTCCGGCGCCGGCCTCAGTCTAGGCCTCAATCTCGGCCAGGGCGTTGGCGGAGTAGGCGGAGGAGCGGAGCAGGCCAGCTGCTATGCGTGCAGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAACCTGATCATCCACCAGCGGACGCACACGGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTTGAGTGCTCGCACATCCAGAAGCTGATGAAGCACATGCGGGTGCACCGCAGTCCGGGCGACGACCAGGACGGACAGGACGGGCCCGACGACGGCAGCAATGCCGATTCGCTGGAGACGAACGAGGCGGACAACGACGAGGATCCCAATCCCGACGATTCCGAGGAGGAGATGGGCGACGCCGATGGGGACAATGATCCCGATGGCGATGTCGATCCCGATGCCGATGGCGAGGGCgacgatgaggacgaggacgagctGGACGACTGCGAGGACATGGACTACAAGGCCGAGGATCTCAGCGTGAGCAATCGCATCGACggcaagagccagagccccaAGACGACCAGCTCCGGGGCCACCTCCCTGGTCGGGGAGCTGATGGACAAGTTCGGGCTCTCGAACATCGCCCAGTACAGCGAGGCCTACAAGCAGGCGCTGCAGGAGTCCGGCCGCAAGGAGGCCGCCTCCgtggccgctgccgccgccgcggccgccgcagccgccgctgTGGACAACAACAACCGCGGTGGCAGCTCCGGACCTGGCTCCGCCTCAGGAGCGGCTGGAGCGGGTGGGGCCGACAAGATGAACGGCCTGCCCGTGGCCGCGCTCCGGCTGCGGGACGAGTTCGCCAAGAACTGCAACATGTTCCAGCAGCCGCAGGATGGGCCCGGCCAGGTGCCGCTCTTCAACCCCTTCCCCAACCCCTTCGAGCTGAGCAAGCGCATGAAGATGGACGGCGGCGACTGGTGGGGCATGTCCGCCCTGCACCGCAACGAGGCGCTCTTCGAGAACCTCAAGCTGAAGCCCCTGGGCCTGGGCGGGGCCAACGCCCTCATCCAGGGTccgctgctgaagaaggagAGCCGCCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACGGTGCACCGCCGCAGCCACACGGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCCTACGCCTGCGCCCAGAGCTCGAAGCTCACCCGCCACATGAAGACGCACGGACGCACAGGCAAGGACGTGTACCGCTGCCGGTTCTGCGACATGCCCTTCAGCGTCCCCTCCACCCTCGAGAAGCACATGCGCAAGTGTGTCGTGAACCAGGGAAAGGCGGCAGCTGCCGCCAACGCCGTGGCCGCTGCCCAGGCCGCCCAAGCGGCCGCCCAGCAGCTCCAGGCAGCCGCCCAGCACGCCCAGGCcgcccaacagcagcagcagcagcaccagcagtcccagcagcagcagtcgcagcagcagatgcCCGTGCAGTCGCAGCTGTCGCCCACATGCCCCATGGGCGTGGTCGGGTATCCACCACAGTTCGGAGTCTCCGTGGGGGGCCACAACCTCTCGCTGCCGGGCAGCGTGAGCGGGGACAACGACTCGAACGCGTCCTCCAGCCTCACCGCTCACCCCATTTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCSTQGPQMDRDAEEGRPLSLVNRRPSISAIPITGRNSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETAATTLDSNAVASMRGSPAAIERQAAGDSSCDLLDEEQHPHTPKVKQEPYAGDEEMPQLDHEQEQEQEQSVADCQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEATGGATLTVATPAALNNSALAAAAAAAAAAAAVAVGASPQPAEATMKRSSPAGAGVASVSLSTSVSSTSSASLANTSIGSGSNSSHASGSAGVSISASSPQQQQQQQQLQLHQQQQQQQQQQQQAVQQQQQRVQQQQRENLASAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPSVAPLFGHGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVGGQQLNVSANVPTVASGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQAGGASTPGLVGGGSGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSIVNSSSPSPRQKQSPHFASPSPSQIPQHHHHQRPHSLTPPEKSGDAGSENGSLGGLGLALASTPRSASTPPSKGSSSGAGLSLGLNLGQGVGGVGGGAEQASCYACSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPGDDQDGQDGPDDGSNADSLETNEADNDEDPNPDDSEEEMGDADGDNDPDGDVDPDADGEGDDEDEDELDDCEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAASVAAAAAAAAAAAAVDNNNRGGSSGPGSASGAAGAGGADKMNGLPVAALRLRDEFAKNCNMFQQPQDGPGQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANALIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQQLQAAAQHAQAAQQQQQQHQQSQQQQSQQQMPVQSQLSPTCPMGVVGYPPQFGVSVGGHNLSLPGSVSGDNDSNASSSLTAHPISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564188;
90% Identity: iTF_00603587; iTF_00581029; iTF_00581030; iTF_00517965; iTF_00474034; iTF_00575094; iTF_00536283;
80% Identity: -