Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: -
Assembly: GCA_035043285.1
Location: JAWNNB010002045.1:1373826-1376982[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0043 0.31 11.7 5.0 1 23 170 193 170 193 0.97

2 16 0.0003 0.022 15.3 1.2 1 23 239 262 239 262 0.95

3 16 0.0036 0.26 11.9 3.6 1 23 329 352 329 352 0.95

4 16 0.0015 0.11 13.1 0.7 2 23 410 431 409 431 0.97

5 16 7.2 5.2e+02 1.6 1.1 1 20 544 563 544 565 0.88

6 16 0.015 1.1 10.0 0.5 1 23 574 596 574 596 0.94

7 16 0.00012 0.0084 16.6 0.9 1 23 603 626 603 626 0.97

8 16 0.0008 0.057 14.0 0.8 2 23 635 656 634 656 0.95

9 16 0.0038 0.27 11.9 0.1 2 20 683 701 682 706 0.90

10 16 0.0018 0.13 12.9 1.6 1 23 741 764 741 764 0.96

11 16 1.4 1e+02 3.7 0.6 3 22 773 792 771 792 0.95

12 16 0.35 25 5.7 1.9 1 23 801 824 801 824 0.95

13 16 4.2e-05 0.003 18.0 0.1 1 23 846 869 846 869 0.97

14 16 0.039 2.8 8.7 0.2 1 23 879 901 879 901 0.94

15 16 6.7e-05 0.0048 17.4 3.7 1 23 907 929 907 929 0.99

16 16 6.9e-06 0.0005 20.5 3.2 1 23 935 957 935 957 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0043	0.31	11.7	5.0	1	23	170	193	170	193	0.97
2	16	0.0003	0.022	15.3	1.2	1	23	239	262	239	262	0.95
3	16	0.0036	0.26	11.9	3.6	1	23	329	352	329	352	0.95
4	16	0.0015	0.11	13.1	0.7	2	23	410	431	409	431	0.97
5	16	7.2	5.2e+02	1.6	1.1	1	20	544	563	544	565	0.88
6	16	0.015	1.1	10.0	0.5	1	23	574	596	574	596	0.94
7	16	0.00012	0.0084	16.6	0.9	1	23	603	626	603	626	0.97
8	16	0.0008	0.057	14.0	0.8	2	23	635	656	634	656	0.95
9	16	0.0038	0.27	11.9	0.1	2	20	683	701	682	706	0.90
10	16	0.0018	0.13	12.9	1.6	1	23	741	764	741	764	0.96
11	16	1.4	1e+02	3.7	0.6	3	22	773	792	771	792	0.95
12	16	0.35	25	5.7	1.9	1	23	801	824	801	824	0.95
13	16	4.2e-05	0.003	18.0	0.1	1	23	846	869	846	869	0.97
14	16	0.039	2.8	8.7	0.2	1	23	879	901	879	901	0.94
15	16	6.7e-05	0.0048	17.4	3.7	1	23	907	929	907	929	0.99
16	16	6.9e-06	0.0005	20.5	3.2	1	23	935	957	935	957	0.98

Sequence Information

Coding Sequence: ATGACCCGGACCTGCAGAATCTGTGGCGATGCAAATGGGCGTTACTGGATTGAGACGCCGGTGGAGAAGTATGCCGAGAAGACCTTTAACCAGCTGCTGTTGGAGCTGACCAAGATTGAGTTGACCATGGTCCAGGCCGAGAAGTTGCCCCACTGGATCTGCTCCAGTTGCTCCCAGAAGCTGGAGAGCGCCTATGACTTTGTGCTGCAGGCGCAACAGACGCACAAGCTGTGGCTGCAACAACTGGAGGATACGGGGCAGACAATGAGCACTGGGGCCTTGGAGTGCCTGCGGGAGACACCCATACATCTGTTTGAGATCGAGGGTGTTACCATCAAAACCGAAGCGCTAGAGTCAACCGTGACAGACAACGGGAACAGCTCGTCCGATCCTCTAGTCCGCACACGCGTCAAGAAACGGACCATCTTTCACTTCAGCGACACGGAGGATGACCAGGATGATGTGCCACTGAGGCAGCGCAGGATGGGGAGCTCATTAGAAAAGCTGCATAAGTGCAATCTGTGCGTGAGATCCTTTAGATACATCACAAATCTGTATCGCCACAAGAAAAAAGATCACGGCTATCCAGGGCGTTCGAAGCGTGAGAGCTCCGAATCCTGCCAGGACAGCACACAAAAGAGCGCCGTGGCAGCGCAGGACAGTTCCAATGTGGAacaaaacgatgatgataatgatgggGATGATGACAACTACTACAAATGCGATCAGTGCGACAAATCCTTCAAGTACCTAATGGTGCTGGTCAAGCACAAGCAGAATGCCCATGAAGACAATCAATACCAAATGCCAATCAGATCTGGGCCCAAGCGAAGGAACAGAAGGGATGTGGGTGAAGCGGCCAGTCCAGCTTCTTCCGGGACATCCACACAACATGCCAGAATCAACAACGACAGCCTCGTCCATAGCCTCATCAAAACAGTGGAGTTTTCGGATGAGAATGCAGACAGCGGCACCGATCACTACTACAAGTGTGATCAGTGCCACAGATCGTACACATACATCGTAAGCCTCATCAAGCACAAGTACAAGGATCACAGGGAAGCCGACGACAAAAACTCGGACGCGGACGAGGACAATCAACCATTGGCCTCCACATCTGCCTGCGCCTCCGCAGCCTCGGTCGCTGCCACCAAGGCTTCGCGAATCAATCGTCGCGTGCAGGGCTTCGACCTGCATCGCTGCGAGCCGAATGGTGCGAAGGAAATTCAGTGCATGATCTGTCTGCGGAAATTCACAAAGCTTCGGGAGCTGAGAGATCACCTGAGGGCGCATCCCGCCGACTTTAATTTCCAGGCGCACGGCGAGCCCATCGAACGCATTGCCGAGGGCTTCTTCAAGACGGCTGTGGAGTCGACTGTGGAGGGCTTGAAGAAGCGAATTCAGCATGATCTCAAGATGGGCGTGTTTGGACGCTTCTATTCCATTACCAATGAGGCGCGCTACGAGATGAGTTTGGACAGCTCGGACACGGATAGCGATGGCGATGCAGATGTAGTACTGCGACGAAGCTATGCCTGCGAACTATGCGACTCGCCTGAGGCCAGGTGGCCGCGCAAGTATCAGCTGCACGAGCATCACAGGCAACAGCACACCTGGGAGGAGGCTCCGCATGTCTGCCAACGCTGCGACTCGCGTTTCCTCAGTCTCCAGCTGCTGGAGCATCACACCCTTCAGCTCTGCCAGAACACACTGAAGCGATACATGTGCGACAAGTGTCCGCAGCGCTTCTTCTGGCGAAGAAATCTGCGTGCCCATCTGGTGGAGCACAAGAGCAAGCAAGACAACTATCCGTGCGACCAGTGCCAGCGTAGCTTTCAGGACAAGAGCGCCGTGACCAAGCACAAGTTGACGATGCATCGCGATGAAAAGAATCAGCTTATTCCCTGCCGCTGGTGTTCGCGGACCTTCTATCGTCCCGCGCTCCTGCACAAGCATGTCGAACGGCATGGCTTCACCGGCGACGATTTACCACTGGCGGAAACATTGCTGGCCGATGCAGCCAAGCCAGCGGGCCCAAAGACGGTGCAGTGCAAGATCTGTGACCTGCAGTTCGTAAGCGTAGCGGATCTGCGCCGTCACAACGCAATGCTGGGCCACAGTGAGCGCTTAACCGACTACATGATCAGCACCGAGGCTGGcttcgagctgctgctggaggacaCAGATGACAGCGATGACGACACTACGGGGGGCAGGTCCTACTCGTGCGATCTCTGTCAGATGACGTTCCGTCGCCGCAGGGAGATGAGCGAGCATCAGTATTCGCTGCACGCATTCGACAAGCTGCCGTATGGCTGCGAACATTGCATTTACAAGACCGTGGATAAGATCATGCTGGAGCATCATCTGCGCACACAATGCCTGAACAGCGAGAAGCCATTCAGCTGCTCCCGCTGCCGATACAAGTTCATGTGGAAGGAGAACCTGGAGCAGCACTTTGCCACTCAGCATCCCAAGCAGCCGCCCGCCCAAGAGCAGTCGTCTCTGCCCCTGAGAAGAAGGCGACGCTTCAGGTACCAATGCCCACAGTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTCGATAAGCACATAAGGGACATGCATGTGGCCAAGAGGAATCCGGGCAAGAAGTATCTCTGCTCGCTGTGCGGCCTGGAGTCGCTGACGCCCAACAAGcttaacatacatatgcgtCGCCACAACGGAGAAAAGCCCTTTAAATGCGATCTGTGCGACATGCGCTTCACCGTCCACTACGAGCTGAAGGTCCATCGGCGGAAGCACACCGGCGAGCGGCCCTATCAGTGCACCTTCTGTGACAAGCATTTCGCGCGACCCGACAAACTGAGACGCCATGTCTACATGCACAGTGCTCGTCGTTAG
Protein Sequence: MTRTCRICGDANGRYWIETPVEKYAEKTFNQLLLELTKIELTMVQAEKLPHWICSSCSQKLESAYDFVLQAQQTHKLWLQQLEDTGQTMSTGALECLRETPIHLFEIEGVTIKTEALESTVTDNGNSSSDPLVRTRVKKRTIFHFSDTEDDQDDVPLRQRRMGSSLEKLHKCNLCVRSFRYITNLYRHKKKDHGYPGRSKRESSESCQDSTQKSAVAAQDSSNVEQNDDDNDGDDDNYYKCDQCDKSFKYLMVLVKHKQNAHEDNQYQMPIRSGPKRRNRRDVGEAASPASSGTSTQHARINNDSLVHSLIKTVEFSDENADSGTDHYYKCDQCHRSYTYIVSLIKHKYKDHREADDKNSDADEDNQPLASTSACASAASVAATKASRINRRVQGFDLHRCEPNGAKEIQCMICLRKFTKLRELRDHLRAHPADFNFQAHGEPIERIAEGFFKTAVESTVEGLKKRIQHDLKMGVFGRFYSITNEARYEMSLDSSDTDSDGDADVVLRRSYACELCDSPEARWPRKYQLHEHHRQQHTWEEAPHVCQRCDSRFLSLQLLEHHTLQLCQNTLKRYMCDKCPQRFFWRRNLRAHLVEHKSKQDNYPCDQCQRSFQDKSAVTKHKLTMHRDEKNQLIPCRWCSRTFYRPALLHKHVERHGFTGDDLPLAETLLADAAKPAGPKTVQCKICDLQFVSVADLRRHNAMLGHSERLTDYMISTEAGFELLLEDTDDSDDDTTGGRSYSCDLCQMTFRRRREMSEHQYSLHAFDKLPYGCEHCIYKTVDKIMLEHHLRTQCLNSEKPFSCSRCRYKFMWKENLEQHFATQHPKQPPAQEQSSLPLRRRRRFRYQCPQCWRSFVVQPSLDKHIRDMHVAKRNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSARR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575022;
90% Identity: iTF_00481028;
80% Identity: -