Basic Information

Gene Symbol
-
Assembly
GCA_035043285.1
Location
JAWNNB010001098.1:3587134-3590783[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.031 2.3 9.0 0.3 2 23 338 360 337 360 0.96
2 18 1.2 85 4.0 0.2 1 23 367 392 367 392 0.94
3 18 0.037 2.6 8.8 2.2 2 23 403 424 403 424 0.93
4 18 3.7 2.7e+02 2.5 0.5 3 23 465 486 464 486 0.92
5 18 0.022 1.6 9.5 0.4 3 23 494 514 493 514 0.93
6 18 0.00032 0.023 15.3 0.4 1 23 522 545 522 545 0.98
7 18 0.00079 0.057 14.0 0.2 2 23 550 571 549 571 0.97
8 18 1.3 90 3.9 0.2 1 20 579 598 579 600 0.91
9 18 2.2e-05 0.0016 18.9 0.7 1 23 619 643 619 643 0.91
10 18 1 72 4.2 0.5 3 21 650 668 650 669 0.89
11 18 0.0083 0.6 10.8 0.9 1 23 688 713 688 713 0.96
12 18 0.81 58 4.5 1.9 2 23 731 753 730 753 0.94
13 18 0.0099 0.72 10.6 0.3 2 23 759 781 758 781 0.92
14 18 0.019 1.4 9.6 0.2 2 23 785 807 784 807 0.95
15 18 5.8e-05 0.0042 17.6 2.0 1 23 813 835 813 835 0.98
16 18 0.012 0.85 10.3 1.4 1 23 839 862 839 862 0.93
17 18 2.4e-05 0.0017 18.8 1.9 1 23 868 891 868 891 0.96
18 18 6.5e-06 0.00047 20.6 0.7 5 23 904 923 895 923 0.85

Sequence Information

Coding Sequence
ATGTcggaaaacccaaaaacaagcaaaaacgTTCCTAGCTGCCTGCATTGCAGCGCATACGGTTCGAAAGGGAGGTACCAGGAGATATTTGATGAATTTGGCCTGGAACTGGgactccagcagctgctggcgaaGCACTTCGACTTGGATGTGACGCCGAAcgcaaagcagcaacagatcCTTTGCGGGGAGTGCGTAAATGTTCTGATCCGGTTATTTGACATTGAcgagctacagcaacagcaagatgCTGCGATTGCCAAGAAAAAGATCGCTGCTGCACAGGTTTCTCCCGCCGCAAAGAGTGCATCCAAGACGCCTCCACAGACGGCCAAGCCCGTGGCCAAGAAGGCAACGCCGCCGAAGCTACAAGCCAAAGTTGTAAAGGTTGTGCCGGTGGTCCAATTGAGGGAGCGCAGCCGacgtataaataaaatttcggCCGGGGCACTGGCATCTGCTGCCTCCGTAGCAGCCGTAGTTGAAAAAGTCACGGCGCCATCCAAAACTACCGTGCAGGCGTCTTGTCCCACTACAAGAGCTAAGCGTGCTGCGAAGGACGCAGACCAGGAGCAGATTAGTGCCCTTATTCTCAATATTCTAAACGAGGATGAGCCGGACATGGAAGATGAGGCAGATAATGTTGCTCCCGACTCTCCCCAATCGccagcagaaaagaaaagtcgAACAACAATTGATGTGCCTGAGGAGGAAGCGGGGACGGAGGCAGTGACTGAAGAAGATCTAGATGGAGTGGATATTATATACGAGCATGAGGATATTTTACTTGAAGAAGAGGTAAATACCAAGCCAGACATCCGTGAATCCAGACCACAAGTGCAGAAAAGGGATAGCCAGAGCGAGGCGGAAAACGAGGAGAGCGGGACCAGCAATATTGTCGTCTTCAACTTTGTCGAGATCAAAGAAAAGGATGAAATTGACGACCTATACGAATACTTGAGCACGGTGGTGAGGACCAGCTTCCAAAGGCTAACCTTTGACTGGAGCACTGTCTGCAAACTGTGCACAATTAAGTCCGCTACCTTCGAGAACCTGCTGGAGCACATGCTGAAGGTGCACAAGTCCCGGGAGGATGACTTTCAGTGCCCAATCGAGGGCTGTAGTAGGCAGCTAAAAGGATGCAAACTTCTGGCCATGCATTTGGTGGTTCTACATGCACCTGTGGCTGATATTACCATTTACGGTAGCTGTCCGGAATGCAAGATGACATTTTCCAATATTTTGCAGTACAATAAACACTCGTGTGCGCATATCATCAAGAAGAAGCGTGGCGTTCGTTTGTATTGTGAAATGTGCGCTCTGGAGTTTCCCTCCTGGAAGCGCTTCAATTTTCACAATCAATTCCATTTGGAGAAGCACCGACCGCGTGCGTGCTTTGTCTGTGGCTATGAGAACACCAACATTGATGAACTCTTCCAGCATTTGCATTATTCCCACGAGCCAGAGGGCACCCGCTTCTGTGATCTCTGCGATCGCACTTTCCGGGATCCCGCTGTGTTTTCGGAGCACAGCTCGTCGCATGCGAATGTGAGCAACACCATCTACTCCTGCAACGAATGCTTGGCTAGCTTCGAGACGCGCGGCCGATTGAATGGCCACATGAGAACAATGCATGGCAATGTCATCAGCTGTGAGCTCTGCTCCCGCGAGTTTGCTTCTGAGGCCACCTACAACGTGCACATGAAATCCCATTTGATTATCGAACGGGAAGTTCATGTCTGCAGCAATTGTGGCCAGCTGAGTGAGAATCAGGAGAAAATGAACGATCACTTGGGGACCGAGGGCTCTGCCTGCCTTGGGGCGGAGAGTTGCGTGGAACTGCTACGTGATGCCTATGTCTGTGAATACTGCACAACGTACTTTAAGCAGAAGTCTGATCTACAGGCCCATCGCGATACCGGTGTACACAACAATGGGATATTTTGGTGCCAGCCCTGCGAAAAGGAATTTCCCGACATGAAATTGTATCGCCACCATTTGCGCAACTATCAACAGCTGCGCATAGATGTAGCACATCGGAAGCTGGACATTTGCACCTTCTTCATGTGCGATCAGAAGGACTGCTCGGCGTCATATGCGAACTGGAACTCGCTGTATACGCACAAGCGGCGAACTCACGATACGCCCgacaagcagcaggagaaatTCGTCAAGCCGTTGCAGGAATGGCAATGCCAATTCTGTCTGAAGCTATGCCGATCGAAGATGTCCCTATCCGTCCATGTCGCTCGGAGCCATAATAATGACAATGTGGTTTGTTCGCTGTGCAACGCCTCGTACAAGAGCAAGGAAGCCCTGGCCAGCCACCATGACTACTGGCACGAGCCCATCGAGTGTCCGCAGTGCTTCAAGATAGTCAAGAACCGGCGCAACTACGACACCCACGTCAATGTGGTGCACTCAAACAAAAAGCGCTACACTTGCAGTGTTTGCGAGAAGGGATTCTACCACAAGAGCGAGATGGAGGCTCACAAGAGGCTCCATTCCCAGTCGTACAGTTGCGAGCAGTGCAGCTTCACCACCAggaacaagaagtcactgtcTGTTCATACGCTGGGCCAGCACTTCAAGCGATTCGCCTTCGACTGCAAGATGTGCGGCAAACACTTTGGTCGACGCCAGGGACTGACCAATCACATCCAGCGTGTGCACGCCTCCAAGCATGTGTGCCGTAACTACATTGATGACGGCTGCGGACGTTCGTTTACCACCAGTTCCCAGCTTAACATACACCTGCGCAAGGTGCACAACTCCACTTTAGTAGCCGACGATGTGGGCGAAGAAGAGACTTATGTCATTGCCAGGCCGTCGGCAGCGAAGAAACAATGTTTTGGAATTGGGCAAGATGCCAAAGAAGAGTTCAGAGACGACGACACGATGAAAGACGCTGATGACAACATTGAAGAGGAGGTGGATGAAGAGGATGTGGAGGAtgggaggaggaagaggaggatgaATCATGGAAGAAAACACCGTTCGGATGATTAG
Protein Sequence
MSENPKTSKNVPSCLHCSAYGSKGRYQEIFDEFGLELGLQQLLAKHFDLDVTPNAKQQQILCGECVNVLIRLFDIDELQQQQDAAIAKKKIAAAQVSPAAKSASKTPPQTAKPVAKKATPPKLQAKVVKVVPVVQLRERSRRINKISAGALASAASVAAVVEKVTAPSKTTVQASCPTTRAKRAAKDADQEQISALILNILNEDEPDMEDEADNVAPDSPQSPAEKKSRTTIDVPEEEAGTEAVTEEDLDGVDIIYEHEDILLEEEVNTKPDIRESRPQVQKRDSQSEAENEESGTSNIVVFNFVEIKEKDEIDDLYEYLSTVVRTSFQRLTFDWSTVCKLCTIKSATFENLLEHMLKVHKSREDDFQCPIEGCSRQLKGCKLLAMHLVVLHAPVADITIYGSCPECKMTFSNILQYNKHSCAHIIKKKRGVRLYCEMCALEFPSWKRFNFHNQFHLEKHRPRACFVCGYENTNIDELFQHLHYSHEPEGTRFCDLCDRTFRDPAVFSEHSSSHANVSNTIYSCNECLASFETRGRLNGHMRTMHGNVISCELCSREFASEATYNVHMKSHLIIEREVHVCSNCGQLSENQEKMNDHLGTEGSACLGAESCVELLRDAYVCEYCTTYFKQKSDLQAHRDTGVHNNGIFWCQPCEKEFPDMKLYRHHLRNYQQLRIDVAHRKLDICTFFMCDQKDCSASYANWNSLYTHKRRTHDTPDKQQEKFVKPLQEWQCQFCLKLCRSKMSLSVHVARSHNNDNVVCSLCNASYKSKEALASHHDYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNKKRYTCSVCEKGFYHKSEMEAHKRLHSQSYSCEQCSFTTRNKKSLSVHTLGQHFKRFAFDCKMCGKHFGRRQGLTNHIQRVHASKHVCRNYIDDGCGRSFTTSSQLNIHLRKVHNSTLVADDVGEEETYVIARPSAAKKQCFGIGQDAKEEFRDDDTMKDADDNIEEEVDEEDVEDGRRKRRMNHGRKHRSDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00487475;
90% Identity
iTF_00564117;
80% Identity
-