Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: -
Assembly: GCA_035043285.1
Location: JAWNNB010001730.1:853344-856417[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.5e-08 2.5e-06 27.7 0.9 1 23 215 238 215 238 0.97

2 17 0.0032 0.23 12.1 0.4 1 23 245 267 245 267 0.98

3 17 0.23 16 6.3 0.1 2 23 299 320 298 320 0.94

4 17 4.5e-05 0.0033 17.9 3.1 1 23 409 432 409 432 0.97

5 17 0.29 21 6.0 0.5 1 19 439 457 439 460 0.94

6 17 0.027 1.9 9.2 5.2 1 23 469 491 469 491 0.95

7 17 2.2e-05 0.0016 18.9 0.7 1 23 498 521 498 521 0.97

8 17 9e-05 0.0065 17.0 1.2 2 23 529 550 528 550 0.96

9 17 0.0012 0.087 13.4 0.1 2 21 577 596 576 597 0.94

10 17 0.0048 0.35 11.5 2.7 1 23 645 668 645 668 0.98

11 17 0.02 1.4 9.6 1.9 1 23 705 728 705 728 0.96

12 17 0.00014 0.0098 16.4 1.6 2 23 757 779 756 779 0.95

13 17 0.00012 0.0087 16.6 0.2 1 23 793 815 793 815 0.95

14 17 0.00014 0.01 16.4 1.1 1 23 821 843 821 843 0.99

15 17 3.6e-07 2.6e-05 24.5 2.3 1 23 849 871 849 871 0.98

16 17 4e-05 0.0029 18.1 3.8 1 23 877 899 877 899 0.97

17 17 0.0005 0.036 14.6 0.4 1 22 905 926 905 929 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.5e-08	2.5e-06	27.7	0.9	1	23	215	238	215	238	0.97
2	17	0.0032	0.23	12.1	0.4	1	23	245	267	245	267	0.98
3	17	0.23	16	6.3	0.1	2	23	299	320	298	320	0.94
4	17	4.5e-05	0.0033	17.9	3.1	1	23	409	432	409	432	0.97
5	17	0.29	21	6.0	0.5	1	19	439	457	439	460	0.94
6	17	0.027	1.9	9.2	5.2	1	23	469	491	469	491	0.95
7	17	2.2e-05	0.0016	18.9	0.7	1	23	498	521	498	521	0.97
8	17	9e-05	0.0065	17.0	1.2	2	23	529	550	528	550	0.96
9	17	0.0012	0.087	13.4	0.1	2	21	577	596	576	597	0.94
10	17	0.0048	0.35	11.5	2.7	1	23	645	668	645	668	0.98
11	17	0.02	1.4	9.6	1.9	1	23	705	728	705	728	0.96
12	17	0.00014	0.0098	16.4	1.6	2	23	757	779	756	779	0.95
13	17	0.00012	0.0087	16.6	0.2	1	23	793	815	793	815	0.95
14	17	0.00014	0.01	16.4	1.1	1	23	821	843	821	843	0.99
15	17	3.6e-07	2.6e-05	24.5	2.3	1	23	849	871	849	871	0.98
16	17	4e-05	0.0029	18.1	3.8	1	23	877	899	877	899	0.97
17	17	0.0005	0.036	14.6	0.4	1	22	905	926	905	929	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTAATTTGTCGGACATGTGATGCGACAGATGCCGATAATCTTTTGAAGCTGGCCACGCCCACGAAGAAGTACCCAGACAAGTTGCTTTCGGACATCTTGAGCGAACTCACGTCCATTAATATTAATCTGGACACATCTGCTAACCAGAAGCTTCCACAGTGTTTGTGTAGCAGTTGCACCAAGAAATTGATTGGTGCCTATTGCTATGTAAGGCAATGCAAGGCCGCCAATGATCTATTGCTAAAGCACCTAAAAAACGGTACTGATTGCTTGCAAGAAACGCCCATGGAACTATGTGCAGAGCAGCATGTGATGGTGAAGCTAGAAACGGAGGATGAGGATGGCGGGGAATCTGAAACAAACATAAATTGCTCCGGGCTACCTGAAATTGTCCCAGAAGAGAGCCCAGACGAAAAAGATTTCGACAACAAGAAATCTGTTGATCCTCTAATAATGATCGATTCTGTTAAGCAGGAAATTGTGCTGACCAGGATGGAAAAGCATGTAGATTACGAAGCCGTGTCTGACTTTGAGGACGAAGACTCGCTGGATAACTTGCCACTGGGACAGCGCATACTAAAATGGAAGACGGGAAACGGCGATTCCCTGCGAAGCCTGAACCTGTCGCTTTACCAGTGCAATGAATGCCCAAAGAGCTTCAAACGAGCCGATTATCTGAAACGACATCAAATCAGGGCTCATAAGCCAGAATCCCGCTGGTTCTCCTGTTCACTCTGCATCCGGAAGTTCAATAGCAGCGAGGCCTTGGAAATGCATCTTAAAGTACATCGAAATCCCAAGCGCTCGGGCAACATAAGTGAGCATAAAAAGGCAAAGTCTGTGGATCTAAATCTTTGCAAGCCCCATGGCTACAAGCTCATCGAGTGCATGATCTGTCAGAGTCAGTACAACAAGATTGCTGATCTGCGACGCCATTTGGAGGAGCATCCGGAAATTATTAGCTTGGGAGTGCGCCCGAATATGGAGCCCAATGAGTTGGCCGAGTTGATCTATCCCGATGCCAAGGATGTAGGCGAGgatcaattaattaacatgATTCGCAAAGATTTGGCAGGCGGGATTTATCATCGCTTCTATTCAATAACTAATCAGTGTGGCTATGAAATGAACCTAGACAGCTCTGACACTGATAGTGAGCTGGACGTGGAGCCCGAAGATCAGCAAAGAAAGCGAAAAACTAGAAAGGCGCACTACAGCTGCGAGCTGTGCCAACAGAGGTTTACCAGGAAGTATCAACTCTACGATCATCAGCGTCAGACGCACAGCTGGTCCGAAGCACCTCATGTTTGCGGCCGTTGCGATGGCCGCTTTGTCAGCCTGCAAATGCTTAGGCATCATAATGAGTCGCAGTGCAGAAATTCGCAAAAGCGATTCCTTTGCCACAAATGCCCCCTGCGGTTCCGGTGGAAGCACAACCTGAGAGCACACTTCCGAGAGCACCGAATCACTAATCAAACCTTTGAGTGTTCCGAATGCAAGCGTGTTTTTGACAAGAAAAAATCCCTGACTGTCCATTTACTCAGCGCCCATGCTGAGGAATCGAAACTGATTCCGTGTCAGTGGTGTACGCGCAAGTTCTATCGTCGTGACTACCTAGTGAAACATCTAAAGCGGCACGGACTCAAGGAGCAGGACATTCCATTGGCCGAGACCCTGATAGCAGCCACATCTAAGCGGAATGGATCCAAGCGCATTACCTGCAAAATTTGCGACCTGCATTTTGACCGCATCACAGATTTGCGTGCCCACATTCAACTGGAATTAAAGCTGTCTCTCTCGCACCATAGCTACGAGTCCCCGCACAACTACTCTATAACCAATGAATCCGGCTTCGAGATGCAGCTGGAAGATTCGGAAACAGAGGACGAAATACAGCCCGGGTCTGACAACCGTCCCCTCTACGTCTGCGAGCTTTGCAGTGTCCAGTGCAAGCGCAAATTCGAAATGATTCAGCATCAACGGACCATGCACCGCTTCGACAAAATGCCTCATGAGTGTGATAAATGCGTTTTTAAGTGTGTGTCCAagAATATCATGGATCATCATCTTCTAtggcagtgcagcagcacaGAGAAGAAGCATTCGTGCAGCAAGTGCACCTATAAATTCATGTGGCCTGAGAATCTGGAAAAACACGTGCGCCTCCAGCATAGCGAAGTCTCCGAAATCACCAAAGCAGCCAAGCCGTCAAGTGGTCTTGTCGACGATGCCACAGAGGACGGAGTCCAGCTGCTGCAATGCCCGCACTGTGATCGCACCTATCAAATGAAGTCGCGATTGAACAACCACATTCGGGATGTTCATGTCAACGGAGATCGAAAGCGCAAGGATGCGATTAAGAGATTCCTTTGCTCGCTTTGTGGCAGAGAAACGCGgtcggctgctgctctggtTACCCACATGCGACGCCACACCGGCGAGAAGCCCTTTAAATGTGATCTATGTGAAATGGCTTTTCCGAGACACTCGGAGATGGCTTCGCATCGCAGGATGCATACGGGGGAGAAGCCATTCCACTGCACAGTTTGTGGCAAGGATTTTGCCCGGTCCGACAAACTGACGCGGCACATGCTCACCCACAGCGGATTGAAGCCGCACAAGTGCACGTACTGCGAGAAGAGCTACAGGCAGGCCAAGGATCTGAAGCTCCATTTGCAACAGCACACAGGCGAATGTCCATTTATCTGTGGCACTTGTGGCGAACGATTTATACAAAACATAACTCTGGAGAAGCATCGCCTAATGCGCCGCCATTTCGATTGGAGTTTGCCATAA
Protein Sequence: MKLPVICRTCDATDADNLLKLATPTKKYPDKLLSDILSELTSININLDTSANQKLPQCLCSSCTKKLIGAYCYVRQCKAANDLLLKHLKNGTDCLQETPMELCAEQHVMVKLETEDEDGGESETNINCSGLPEIVPEESPDEKDFDNKKSVDPLIMIDSVKQEIVLTRMEKHVDYEAVSDFEDEDSLDNLPLGQRILKWKTGNGDSLRSLNLSLYQCNECPKSFKRADYLKRHQIRAHKPESRWFSCSLCIRKFNSSEALEMHLKVHRNPKRSGNISEHKKAKSVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPEIISLGVRPNMEPNELAELIYPDAKDVGEDQLINMIRKDLAGGIYHRFYSITNQCGYEMNLDSSDTDSELDVEPEDQQRKRKTRKAHYSCELCQQRFTRKYQLYDHQRQTHSWSEAPHVCGRCDGRFVSLQMLRHHNESQCRNSQKRFLCHKCPLRFRWKHNLRAHFREHRITNQTFECSECKRVFDKKKSLTVHLLSAHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGLKEQDIPLAETLIAATSKRNGSKRITCKICDLHFDRITDLRAHIQLELKLSLSHHSYESPHNYSITNESGFEMQLEDSETEDEIQPGSDNRPLYVCELCSVQCKRKFEMIQHQRTMHRFDKMPHECDKCVFKCVSKNIMDHHLLWQCSSTEKKHSCSKCTYKFMWPENLEKHVRLQHSEVSEITKAAKPSSGLVDDATEDGVQLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKDAIKRFLCSLCGRETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSEMASHRRMHTGEKPFHCTVCGKDFARSDKLTRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQNITLEKHRLMRRHFDWSLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487433;
90% Identity: iTF_00611484;
80% Identity: -