Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:12366541-12371830[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00016 0.0094 16.1 1.2 1 23 163 186 163 186 0.96

2 14 0.0017 0.097 12.9 3.1 2 23 235 257 231 257 0.90

3 14 0.0073 0.42 10.9 0.8 1 23 351 374 351 374 0.93

4 14 0.087 5 7.5 3.1 2 23 423 444 422 445 0.94

5 14 0.00046 0.027 14.7 0.2 1 23 514 537 514 537 0.92

6 14 1.9 1.1e+02 3.3 0.1 2 14 556 568 555 580 0.85

7 14 0.00066 0.038 14.2 3.3 2 23 588 610 588 610 0.96

8 14 7.9 4.5e+02 1.4 0.0 1 20 696 715 696 717 0.89

9 14 0.00037 0.021 15.0 0.2 1 23 751 774 751 774 0.93

10 14 0.0023 0.13 12.5 1.5 2 23 824 846 823 846 0.95

11 14 0.018 1 9.7 1.8 1 23 937 960 937 960 0.91

12 14 0.028 1.6 9.0 1.2 1 21 1012 1032 1012 1033 0.95

13 14 0.8 46 4.5 0.2 3 23 1065 1088 1063 1088 0.85

14 14 3.5 2e+02 2.4 0.1 1 10 1106 1115 1106 1122 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00016	0.0094	16.1	1.2	1	23	163	186	163	186	0.96
2	14	0.0017	0.097	12.9	3.1	2	23	235	257	231	257	0.90
3	14	0.0073	0.42	10.9	0.8	1	23	351	374	351	374	0.93
4	14	0.087	5	7.5	3.1	2	23	423	444	422	445	0.94
5	14	0.00046	0.027	14.7	0.2	1	23	514	537	514	537	0.92
6	14	1.9	1.1e+02	3.3	0.1	2	14	556	568	555	580	0.85
7	14	0.00066	0.038	14.2	3.3	2	23	588	610	588	610	0.96
8	14	7.9	4.5e+02	1.4	0.0	1	20	696	715	696	717	0.89
9	14	0.00037	0.021	15.0	0.2	1	23	751	774	751	774	0.93
10	14	0.0023	0.13	12.5	1.5	2	23	824	846	823	846	0.95
11	14	0.018	1	9.7	1.8	1	23	937	960	937	960	0.91
12	14	0.028	1.6	9.0	1.2	1	21	1012	1032	1012	1033	0.95
13	14	0.8	46	4.5	0.2	3	23	1065	1088	1063	1088	0.85
14	14	3.5	2e+02	2.4	0.1	1	10	1106	1115	1106	1122	0.79

Sequence Information

Coding Sequence: ATGGAGGGCATGGATCTGTGGACGTCGATGTTCTCCTCGGATTTCGAGGAGGGTGAGCCGGAGGCGGAACTGGAGGACAGCGAGCAATACAATGGCAATGATGATTTCCTTGGCGATTCGGAAATCCTAGCAGGCGATGCCATTGATGACCTACTGGATGGCGAAGATGACGAAagggaggaggaggaggaggaggactaTGGGAATGCTGCCTCTAGGGGACCAAAGCAACCCGATCCCGACGACGATGCCCTCTTTGACTTCGAAATGGAACCCATTGTGAGCATGGCAGAGCCACAGCATCCGGTTTTGGCTCCTGCTGGTCCAATGGGACAGCAATTGCGTCCCCCAATGCAGCGCCACTCGTTTCCCGGCACTGTGGGTCGTCCCAGATTGGGTCCTGGACTCTCCGTACGCCCCACCACCTCGCAGATCAATGCCACGGATGAGAACGGTGTGCTTATCAACTACGAACTGGGCGTGGTCTACATATGCCCCGCCTGCGGAGGAGAGTTCCGGCAACAGGACCACTGGAAGCGGCATATGAACCACATCCACAAGTACAACACCCTGCGCGGACTGAACTTCACGCCGCTGGACAAGCTCTATCAGCGCTGCAGGGAGTGCAACAAGCGGATCGCCATGCACAGCCGGGAGAACCTgctgaagcacaagttcacgCACCTGCCATTCCGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGGCAAGACCTAATGGTGCACCTGCGCATGGTCCACTGCGACGAAGTGGTGGCCATGATGCGGGAGGGTTACAATGCTGCGGGACGCAAGACACGGGTTCGTGAATCGCGCACCGAGCAGTTGCAGCGGGAGAAGAGTTTCCGAGAGAATAATGACTTCGAGGAGGACCTAGATCGCATTGAGGTGCGAAATGAGCTGCTCGAGCCGGATGGCGATGAGGTCGTTCCCCTCGAACGACCTTTACCGGAGGAGGTTTCCAAGAAAAAATCGACTAGCAATCGAGGAGCAGCCGAACTGTGCGAGGACTACATACACTACATGTGCCCTGACTGTGGCACCGAGTGCGACACCCATGCCCAGTGGAGCCAGCACATCGAGTTCGTCCACGACTATGTCAGTCGGCGGGGACTTAATTTCCGGAGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAAAAAATTGTGACCCCCAACACCATTAAATCGCTGCGCGCCCACAAATTTAGCCATTTGTCGCAGCCCGAGTGGCTGCGCTGTAAACTGTGCTACAAGGGCTACACGGATCATCAGGAAGTGGTCAGACATCTGCTGCAGCACCACCATATGAACACGCTGATGCCCGAGGAAGCCGAGGAAGATGCTGAAGCTCCAATGACCATAATGGCGGAAGATGAAGTCGTCGAGGATAGTGGAAACGGCGAGGGAAATGGGGCCCCCTTAGACGAAGACTCACCCTACTTTGAGGACGCACCCAGACGCGGTGGTCGCATCAGCAGCGACGACATTTTCGAGCCTCACATCGACTATCTTTGTCCGCAGTGCGGCAAAGAGTTCATCGAGAAGAAGCACTGGCGCGCCCACGTGGTCATGGCCCACAACATGAATGATCTGAACAAGCTTAATTTCGAGATGATCAACGAACGGCAGCTGAAGTGCACTGAGTGCGACAAGATCATCACCAATGCTTATGGGATCCAGAATGCACAGCAGCACAGGATCACGCATCTTCCATTTAAGGCGTACGCTAGGTGTCGTAAGTGCCACAAGTCCTACACGGACAGGAAGGGTCTCGTTAAGCATCTGGCTACCTATCATCGCGTTGGCTGGCCCCAAAAGCCGGGAGGACCTGGCCCACCAGCTCCGGTTCTTACGCCCTCTAAGCAGCCGCGGAAGCAGATCGTAACGGTAGCCAATGAAACGTACGAGATAATCTACCTGGACGACGTTGAGCAAGGCAGCATGGAGGAGGAGAACGACTTTGGCGAACAGATGCAGGCGGATGAGGAGGATTTCCCAATTGCGCCGCCTCCACCACCGCCACCGCCGACCTCGCAAAGTAATAATCATCGTTACAAGTGCGTCCACTGCGCCTCACTCTTCCCCACAACGGCGGCTGTCCGGGCTCACCTCATCGAGACCCGTTGCCGGAAGACGGTTCTCAAAAGGCGTCGACAGTCAATGATGAACTCTCGAGTAATGGACCCATCCGTTCCCACCGTGGAACAAAACTACATCTTCCTGTGCCCCTCTTGCGGCATGGAGTACAAGACCCAGTACGAGTGGCGCCGTCACATCAACGAAGTGCACAACTTTGACAAGCGCCAATACCTAAACATGCGGCAGTTGGATAAATTTCGCTACCAGTGCACCCAGTGCAAGGATATTGTGGCCAATTCGAAGCTGAAGGGCTTGCAGGACCATCACTTCCGCCATCTGCCCTACCGACTGTATCTCAAGTGCCTGATCTGCGGCACCTGCTACAATCACAAGCCGAACATAGCTGCGCATTTGAGGGCCCGCCACGCCATCTACGATAGGGAGACCCCGGCGATGATCACCAAACCGAAGCACGTATACGGCCGCTACAAGGATAACAGTAGGGAGAAGCCCAGACTGCCCACTCCTCCTCCGGCAGCGCCCTCTCCACCGGGATGCTCGTCCTCGGCTGCTTCCTCGGCGATGAGTCGTTCCCTGAAACCCCAGCCTGGCGGCTTACCAACCCGACCCGCTGGTCTCAACACGCTGGAGGACAGCATCTCGTACCACAATGCCGTGGACTTGGACTTCATCACGTACTTCTGCCCCAAATGTAATCAGAACTTTGACTCCCATGCCTTCTGGCGCAAACACATCGTGGAGCAGCACAACTTTAACAGCCGTGAGGGACTTAACTTCCGGCAGATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGGGTGACCGTGACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGCCATTTGCCGCATCGATCGTTCAAGTGCTTGACTTGCGACGGCGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCACCTGAATCGTGACACCAATCGATGTGACAATCGCCCGCACCGCGAATTGGATGACGATGAGGCAGAACAGGAGACGCAGCTGCGGTCCATCTACCACCTGGCGTGTCCGCAGTGCGGTGACAACTTCACAACCAGCAACAAGAAGGAGTGGCGCGAGCACATCAACGATTACCACGGTCTTGCCAAGCTGGACCTTTTGCACATGAACAAAGTTGGCGAGAACCTTTATCGATGCCAGGACTGTGACGAGGAGCTGCAGACAAATCGACAGTGGGTGCTACAGTTCCATCGATTCCAGCACCTGCCCCACCCGGCCTACATCCGTTGCAAACTGTGCAAGCAGAGCGGCGAGGCGGGCACGGCAACAGCGGGAGAGTTGCACAGTCTTCGTGAGCTGCAGCAGCACCTTCGTAAGCACCATACTGTGGTGGGCGAAAATGAGATGATATTACTCCGTGAGCAAATCGCCATTGAGGAGAAAGAACAGGAGGAGGCCACGGAACTGGCCGAAGACGGGAAAATCCAGGCTACTCAAGATTCAGGGCCGTATATGCCGTTGCCGCCGCATTTATTGGACGATGGAGACGACGTGGAATTCGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSDFEEGEPEAELEDSEQYNGNDDFLGDSEILAGDAIDDLLDGEDDEREEEEEEDYGNAASRGPKQPDPDDDALFDFEMEPIVSMAEPQHPVLAPAGPMGQQLRPPMQRHSFPGTVGRPRLGPGLSVRPTTSQINATDENGVLINYELGVVYICPACGGEFRQQDHWKRHMNHIHKYNTLRGLNFTPLDKLYQRCRECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQLQREKSFRENNDFEEDLDRIEVRNELLEPDGDEVVPLERPLPEEVSKKKSTSNRGAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSQPEWLRCKLCYKGYTDHQEVVRHLLQHHHMNTLMPEEAEEDAEAPMTIMAEDEVVEDSGNGEGNGAPLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRAHVVMAHNMNDLNKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGWPQKPGGPGPPAPVLTPSKQPRKQIVTVANETYEIIYLDDVEQGSMEEENDFGEQMQADEEDFPIAPPPPPPPPTSQSNNHRYKCVHCASLFPTTAAVRAHLIETRCRKTVLKRRRQSMMNSRVMDPSVPTVEQNYIFLCPSCGMEYKTQYEWRRHINEVHNFDKRQYLNMRQLDKFRYQCTQCKDIVANSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHAIYDRETPAMITKPKHVYGRYKDNSREKPRLPTPPPAAPSPPGCSSSAASSAMSRSLKPQPGGLPTRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDGEFVRKQMFFKHLNRDTNRCDNRPHRELDDDEAEQETQLRSIYHLACPQCGDNFTTSNKKEWREHINDYHGLAKLDLLHMNKVGENLYRCQDCDEELQTNRQWVLQFHRFQHLPHPAYIRCKLCKQSGEAGTATAGELHSLRELQQHLRKHHTVVGENEMILLREQIAIEEKEQEEATELAEDGKIQATQDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486896;
90% Identity: iTF_00578912;
80% Identity: -